Jeremy Kay
@jnklab.bsky.social
Neuroscientist, retina nerd at Duke. Dept of Neurobiology & Duke Eye Center. Studying nervous system development, cell-cell recognition, and vision.
Reposted by Jeremy Kay
Our latest paper is out! While the circadian photoentrainment circuit has been extensively studied, the mechanisms regulating its development remain poorly understood. Here we show that retinal Müller glia play a key role in this process. Check it out! www.sciencedirect.com/science/arti...
Retinal glia regulate development of the circadian photoentrainment circuit
Circadian photoentrainment depends on intrinsically photosensitive retinal ganglion cells (ipRGCs), which convey environmental light information to th…
www.sciencedirect.com
October 29, 2025 at 2:27 PM
Our latest paper is out! While the circadian photoentrainment circuit has been extensively studied, the mechanisms regulating its development remain poorly understood. Here we show that retinal Müller glia play a key role in this process. Check it out! www.sciencedirect.com/science/arti...
Reposted by Jeremy Kay
I wrote a quick-start guide for people to replicate this across the country. It was, in our experience, a very effective way to get real action in a short amount of time.
People are willing to talk to scientists! And when you provide everything, they are happy to contact their reps too. Try it!
People are willing to talk to scientists! And when you provide everything, they are happy to contact their reps too. Try it!
June 16, 2025 at 5:49 PM
I wrote a quick-start guide for people to replicate this across the country. It was, in our experience, a very effective way to get real action in a short amount of time.
People are willing to talk to scientists! And when you provide everything, they are happy to contact their reps too. Try it!
People are willing to talk to scientists! And when you provide everything, they are happy to contact their reps too. Try it!
Reposted by Jeremy Kay
I have previously posted about the slow issuance of NIH award in fiscal year 2025 compared to fiscal year 2024.
jeremymberg.github.io/jeremyberg.g...
These data were across all of the institutes and centers at NIH.
The results can be examined for each institute and center.
1/n
jeremymberg.github.io/jeremyberg.g...
These data were across all of the institutes and centers at NIH.
The results can be examined for each institute and center.
1/n
NIH_since_1_20_25
jeremymberg.github.io
May 7, 2025 at 11:59 AM
I have previously posted about the slow issuance of NIH award in fiscal year 2025 compared to fiscal year 2024.
jeremymberg.github.io/jeremyberg.g...
These data were across all of the institutes and centers at NIH.
The results can be examined for each institute and center.
1/n
jeremymberg.github.io/jeremyberg.g...
These data were across all of the institutes and centers at NIH.
The results can be examined for each institute and center.
1/n
Check out our new preprint! Microglia in different layers of the developing retina express distinct gene profiles - implications for how microglia influence development not just in the retina but throughout the CNS.
Microglia and myeloid cell populations of the developing mouse retina https://www.biorxiv.org/content/10.1101/2025.04.07.646926v1
April 8, 2025 at 2:43 AM
Check out our new preprint! Microglia in different layers of the developing retina express distinct gene profiles - implications for how microglia influence development not just in the retina but throughout the CNS.
Reposted by Jeremy Kay
☀️📣 Looking for a STATE LEAD and VOLUNTEERS to help us #standupforscience2025 in North Carolina!
Know someone interested? Fill out this form: airtable.com/app4h5wUssMG...
#scienceforall #sciencenotsilence
Know someone interested? Fill out this form: airtable.com/app4h5wUssMG...
#scienceforall #sciencenotsilence
February 20, 2025 at 1:43 AM
☀️📣 Looking for a STATE LEAD and VOLUNTEERS to help us #standupforscience2025 in North Carolina!
Know someone interested? Fill out this form: airtable.com/app4h5wUssMG...
#scienceforall #sciencenotsilence
Know someone interested? Fill out this form: airtable.com/app4h5wUssMG...
#scienceforall #sciencenotsilence
Reposted by Jeremy Kay
Let's just say it gets bigger everyday... @standupforscifr.bsky.social
We're doing this for the next generation of scientists. To uphold the integrity of science, protect its accessibility, and ensure its benefits serve all people.
Join us.
@standupforscience.bsky.social
We're doing this for the next generation of scientists. To uphold the integrity of science, protect its accessibility, and ensure its benefits serve all people.
Join us.
@standupforscience.bsky.social
Scientists are now organizing events, called Stand Up for Science, on 7 March in Washington, D.C., and state capitals.
So far, they have attracted more than 100 volunteers from some 30 states who are hoping to rally support for research as a public good. scim.ag/4328LAD
So far, they have attracted more than 100 volunteers from some 30 states who are hoping to rally support for research as a public good. scim.ag/4328LAD
‘I really wanted something to happen.’ The students behind the Stand Up for Science protests
New group hopes to turn out researchers for 7 March demonstrations against Trump administration policies
scim.ag
February 19, 2025 at 5:49 PM
Let's just say it gets bigger everyday... @standupforscifr.bsky.social
We're doing this for the next generation of scientists. To uphold the integrity of science, protect its accessibility, and ensure its benefits serve all people.
Join us.
@standupforscience.bsky.social
We're doing this for the next generation of scientists. To uphold the integrity of science, protect its accessibility, and ensure its benefits serve all people.
Join us.
@standupforscience.bsky.social
Reposted by Jeremy Kay
The Senate Committee on Health, Education, Labor, and Pensions, led by Senator Bill Cassidy (R-LA) - a gastroenterologist with an MD from LSU, just released a report entitled NIH IN THE 21st CENTURY: ENSURING TRANSPARENCY AND AMERICAN BIOMEDICAL LEADERSHIP. Since he is the ranking Republican,
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December 18, 2024 at 9:37 PM
The Senate Committee on Health, Education, Labor, and Pensions, led by Senator Bill Cassidy (R-LA) - a gastroenterologist with an MD from LSU, just released a report entitled NIH IN THE 21st CENTURY: ENSURING TRANSPARENCY AND AMERICAN BIOMEDICAL LEADERSHIP. Since he is the ranking Republican,
1/n
1/n
Reposted by Jeremy Kay
Horace Barlow, by all accounts, was thinking about 30 years ahead of his time. Here is a transcript of the opening keynote I gave at a symposium honoring Horace's scientific legacy: markusmeister.com/2024/12/14/h....
December 14, 2024 at 9:41 PM
Horace Barlow, by all accounts, was thinking about 30 years ahead of his time. Here is a transcript of the opening keynote I gave at a symposium honoring Horace's scientific legacy: markusmeister.com/2024/12/14/h....
Reposted by Jeremy Kay
3 reviews on planning, execution, & validation of transcriptomic experiments in neuroscience published in @natureportfolio.bsky.social #NatureNeuroscience.
A MUST READ if you're doing transcriptomics.
3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year!
(mini thread)
A MUST READ if you're doing transcriptomics.
3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year!
(mini thread)
December 11, 2024 at 5:04 PM
3 reviews on planning, execution, & validation of transcriptomic experiments in neuroscience published in @natureportfolio.bsky.social #NatureNeuroscience.
A MUST READ if you're doing transcriptomics.
3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year!
(mini thread)
A MUST READ if you're doing transcriptomics.
3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year!
(mini thread)
Reposted by Jeremy Kay
New preprint! A wonderful collaboration of our @FellerMarla lab with Matthew Po, and @shekharlab. Here, we dive into the impact of spontaneous activity on the transcriptome of retinal ganglion cells (RGCs), the sole output neurons of the retina. www.biorxiv.org/content/10.1...
Transcriptomic changes in retinal ganglion cell types associated with the disruption of cholinergic retinal waves
In the early stages of retinal development, a form of correlated activity known as retinal waves causes periodic depolarizations of immature retinal ganglion cells (RGCs). Retinal waves are crucial fo...
www.biorxiv.org
December 10, 2024 at 11:00 AM
New preprint! A wonderful collaboration of our @FellerMarla lab with Matthew Po, and @shekharlab. Here, we dive into the impact of spontaneous activity on the transcriptome of retinal ganglion cells (RGCs), the sole output neurons of the retina. www.biorxiv.org/content/10.1...
Reposted by Jeremy Kay
RNA-programmable cell type monitoring and manipulation in the human cortex with CellREADR https://www.biorxiv.org/content/10.1101/2024.12.03.626590v1
December 7, 2024 at 1:15 AM
RNA-programmable cell type monitoring and manipulation in the human cortex with CellREADR https://www.biorxiv.org/content/10.1101/2024.12.03.626590v1
Reposted by Jeremy Kay
“While even the agency’s defenders acknowledge that the NIH needs modernization, the radical reforms proposed would be difficult, if not impossible, without YEARS of legal wrangling and significant support from Congress”
Exactly! So let’s work on allies in congress
www.nytimes.com/2024/12/01/h...
Exactly! So let’s work on allies in congress
www.nytimes.com/2024/12/01/h...
Long a ‘Crown Jewel’ of Government, N.I.H. Is Now a Target
The agency long benefited from broad bipartisan support. But Republican criticism has intensified, and new choices for top health posts hope to upend the organization.
www.nytimes.com
December 2, 2024 at 1:15 AM
“While even the agency’s defenders acknowledge that the NIH needs modernization, the radical reforms proposed would be difficult, if not impossible, without YEARS of legal wrangling and significant support from Congress”
Exactly! So let’s work on allies in congress
www.nytimes.com/2024/12/01/h...
Exactly! So let’s work on allies in congress
www.nytimes.com/2024/12/01/h...
Reposted by Jeremy Kay
Parable time: After the incredible successes of quantum electrodynamics in the late 1940s, particle physics went through what is now considered a pretty fallow period in the the 1950s and 60s. Many interesting ideas from that time that survived (selectively summarized much later in Coleman) 1/n
Aspects of Symmetry
For almost two decades, Sidney Coleman has been giving review lectures on frontier topics in theoretical high-energy physics at the International School of Subnuclear Physics held each year at Erice, ...
www.google.com
November 30, 2024 at 2:21 AM
Parable time: After the incredible successes of quantum electrodynamics in the late 1940s, particle physics went through what is now considered a pretty fallow period in the the 1950s and 60s. Many interesting ideas from that time that survived (selectively summarized much later in Coleman) 1/n
Reposted by Jeremy Kay
While our bodies seem static, our cells are constantly changing shape or on the move during tissue homeostasis or wound repair & even more dramatically during embryonic development, during events like gastrulation. Defining how cellular machines mediate these events is a key task for our field 1/n
November 30, 2024 at 2:17 PM
While our bodies seem static, our cells are constantly changing shape or on the move during tissue homeostasis or wound repair & even more dramatically during embryonic development, during events like gastrulation. Defining how cellular machines mediate these events is a key task for our field 1/n
Reposted by Jeremy Kay
This is one of my all-time favorite figures. It shows the size comparison between a retinal bipolar cell and a cortical pyramidal cell in a mouse. Scale bars are great and all but sometimes the sizes just don't compute.
Masland. (2012). The Neuronal Organization of the Retina.
🧪 #neuroskyence
Masland. (2012). The Neuronal Organization of the Retina.
🧪 #neuroskyence
November 27, 2024 at 12:24 AM
This is one of my all-time favorite figures. It shows the size comparison between a retinal bipolar cell and a cortical pyramidal cell in a mouse. Scale bars are great and all but sometimes the sizes just don't compute.
Masland. (2012). The Neuronal Organization of the Retina.
🧪 #neuroskyence
Masland. (2012). The Neuronal Organization of the Retina.
🧪 #neuroskyence
Reposted by Jeremy Kay
Excited to publish a broad set of enhancers to target interneuron types in the brain, along with a broad set of collaborators. Part of the BI armamentarium. Together this will help revolutionize the targeting of brain circuits.https://www.biorxiv.org/content/10.1101/2024.07.17.603924v2
November 24, 2024 at 3:01 AM
Excited to publish a broad set of enhancers to target interneuron types in the brain, along with a broad set of collaborators. Part of the BI armamentarium. Together this will help revolutionize the targeting of brain circuits.https://www.biorxiv.org/content/10.1101/2024.07.17.603924v2
Reposted by Jeremy Kay
New @bioRxiv #preprint with @chiarafornetto.bsky.social and @teuler.bsky.social : www.biorxiv.org/content/10.1...
November 20, 2024 at 9:31 AM
New @bioRxiv #preprint with @chiarafornetto.bsky.social and @teuler.bsky.social : www.biorxiv.org/content/10.1...
Reposted by Jeremy Kay
There are lots of us missing, but so many joining so quickly
Please do share, and comment below to be added
go.bsky.app/5f2V6L6
(microglia starter pack also here by @mancusorenzo.bsky.social - bsky.app/starter-pack...)
Please do share, and comment below to be added
go.bsky.app/5f2V6L6
(microglia starter pack also here by @mancusorenzo.bsky.social - bsky.app/starter-pack...)
November 17, 2024 at 7:10 PM
There are lots of us missing, but so many joining so quickly
Please do share, and comment below to be added
go.bsky.app/5f2V6L6
(microglia starter pack also here by @mancusorenzo.bsky.social - bsky.app/starter-pack...)
Please do share, and comment below to be added
go.bsky.app/5f2V6L6
(microglia starter pack also here by @mancusorenzo.bsky.social - bsky.app/starter-pack...)
Reposted by Jeremy Kay
go.bsky.app/Eaua5Jk my starter for neuroimmunology
November 19, 2024 at 4:50 AM
go.bsky.app/Eaua5Jk my starter for neuroimmunology
Reposted by Jeremy Kay
November 16, 2024 at 5:13 AM
Reposted by Jeremy Kay
Neural development community coming together like Voltron with Sergiu’s Starter Pack!
November 16, 2024 at 2:32 PM
Neural development community coming together like Voltron with Sergiu’s Starter Pack!
Reposted by Jeremy Kay
The retina provides pretty pictures even when antibodies misbehave. I'm calling this one "bipolars in a starry sky".
November 14, 2024 at 12:42 AM
The retina provides pretty pictures even when antibodies misbehave. I'm calling this one "bipolars in a starry sky".
Reposted by Jeremy Kay
"However, since the specific aims are abstracted for internal management and public reporting, including figures can interfere with application processing. Please advise your colleagues and other investigators not to include figures in the Specific Aims attachment of an NIH grant application."
November 12, 2024 at 2:35 PM
"However, since the specific aims are abstracted for internal management and public reporting, including figures can interfere with application processing. Please advise your colleagues and other investigators not to include figures in the Specific Aims attachment of an NIH grant application."
Our paper on retinal mosaic patterning came out in today’s issue of Cell Reports. See below for a thread I wrote last fall and check out the full paper here: www.cell.com/cell-reports...
Congrats to co-authors Chris Kozlowski and Sarah Hadyniak!
Congrats to co-authors Chris Kozlowski and Sarah Hadyniak!
August 27, 2024 at 10:02 PM
Our paper on retinal mosaic patterning came out in today’s issue of Cell Reports. See below for a thread I wrote last fall and check out the full paper here: www.cell.com/cell-reports...
Congrats to co-authors Chris Kozlowski and Sarah Hadyniak!
Congrats to co-authors Chris Kozlowski and Sarah Hadyniak!