Inbal Shainer 🎗️
@ishainer.bsky.social
assistant professor at https://www.technion.ac.il/, studying visual neuroethology in zebrafish 🐟🔬🏳️🌈
https://shainer-lab.net.technion.ac.il/
https://shainer-lab.net.technion.ac.il/
Pinned
Inbal Shainer 🎗️
@ishainer.bsky.social
· Feb 13
Excited to share our new paper in Nature! 'Transcriptomic neuron types vary topographically in function and morphology' explores how neurons in the zebrafish optic tectum exhibit diverse functions and shapes despite similar transcriptional profiles.
🔗 rdcu.be/d9GVM
🔗 rdcu.be/d9GVM
Reposted by Inbal Shainer 🎗️
Convergent thyroid-ATPase interactions regulate collective behavior in Danionella
Convergent thyroid-ATPase interactions regulate collective behavior in Danionella
Zada, Kadobianskyi et al. develop methods for measuring and manipulating gene expression in the schooling glassfish Danionella cerebrum, identifying circadian genes and the thyroid-klf9-atp1a1 pathway as commonly regulated across multiple models of impaired or immature collective behavior.
dlvr.it
January 13, 2026 at 12:23 AM
Convergent thyroid-ATPase interactions regulate collective behavior in Danionella
Reposted by Inbal Shainer 🎗️
Engineering a Mechanoresponsive DNA Origami Capsule for Drug Delivery to Narrowed Arteries pubs.acs.org/doi/10.1021/...
Glad we could contribute to this interesting work from Yuval Garini's lab. Kudos to Hadas Omer and the team:
Hadeel_Khamis, Zipora Lansky, Netanel Korin, Racheli Boeangiu
Glad we could contribute to this interesting work from Yuval Garini's lab. Kudos to Hadas Omer and the team:
Hadeel_Khamis, Zipora Lansky, Netanel Korin, Racheli Boeangiu
Engineering a Mechanoresponsive DNA Origami Capsule for Drug Delivery to Narrowed Arteries
Since their inception, DNA origami nanostructures (DONs) have attracted great interest for their programmable geometry, nanoscale precision, and biocompatibility. Here, we present mechanoresponsive DO...
pubs.acs.org
January 6, 2026 at 1:47 PM
Engineering a Mechanoresponsive DNA Origami Capsule for Drug Delivery to Narrowed Arteries pubs.acs.org/doi/10.1021/...
Glad we could contribute to this interesting work from Yuval Garini's lab. Kudos to Hadas Omer and the team:
Hadeel_Khamis, Zipora Lansky, Netanel Korin, Racheli Boeangiu
Glad we could contribute to this interesting work from Yuval Garini's lab. Kudos to Hadas Omer and the team:
Hadeel_Khamis, Zipora Lansky, Netanel Korin, Racheli Boeangiu
Reposted by Inbal Shainer 🎗️
Reposted by Inbal Shainer 🎗️
Excited to see this preprint out! Siyuan Mei did exceptional work leading this project, and it was a great experience working with the Herz lab. How do zebrafish update their internal compass? They use a multi ring shifter network, similar to flies despite 550M years of divergence. Full thread ⬇️
1/n: A new collaborative preprint from the lab to start the year: "A multi-ring shifter network computes head direction in zebrafish" together with Siyuan Mei, Martin Stemmler and Andreas Herz from the LMU, Munich.
January 7, 2026 at 2:09 PM
Excited to see this preprint out! Siyuan Mei did exceptional work leading this project, and it was a great experience working with the Herz lab. How do zebrafish update their internal compass? They use a multi ring shifter network, similar to flies despite 550M years of divergence. Full thread ⬇️
Reposted by Inbal Shainer 🎗️
Do you love quantifying animal behavior as much as we do? We have just the tool for you! Presenting #OCTRON - a pipeline that helps you create rich annotation data and enables training of custom segmentation models. Have a look, particularly if you work with non-model / invertebrate organisms!
December 23, 2025 at 7:52 PM
Do you love quantifying animal behavior as much as we do? We have just the tool for you! Presenting #OCTRON - a pipeline that helps you create rich annotation data and enables training of custom segmentation models. Have a look, particularly if you work with non-model / invertebrate organisms!
Reposted by Inbal Shainer 🎗️
Do direction and orientation preferences form maps in the mouse superior colliculus (SC)?
We examined how motion and orientation tuning are organized in SC neurons and their retinal inputs—and how the retinal topography is transformed by collicular circuits.
tinyurl.com/mr2zt5rm
🧵👇
We examined how motion and orientation tuning are organized in SC neurons and their retinal inputs—and how the retinal topography is transformed by collicular circuits.
tinyurl.com/mr2zt5rm
🧵👇
December 24, 2025 at 1:41 PM
Do direction and orientation preferences form maps in the mouse superior colliculus (SC)?
We examined how motion and orientation tuning are organized in SC neurons and their retinal inputs—and how the retinal topography is transformed by collicular circuits.
tinyurl.com/mr2zt5rm
🧵👇
We examined how motion and orientation tuning are organized in SC neurons and their retinal inputs—and how the retinal topography is transformed by collicular circuits.
tinyurl.com/mr2zt5rm
🧵👇
Reposted by Inbal Shainer 🎗️
🥁We are recruiting PhD students/Postdocs with strong proven background in developmental/molecular/cell biology & related areas, for various projects- check out our lab website👇🏼
We offer: competitive stipends, super equipped lab, fun international team!
yanivelkoubylab.com
We offer: competitive stipends, super equipped lab, fun international team!
yanivelkoubylab.com
The Elkouby Lab - Cell and developmental biology of early oogenesis
The Elkouby Lab Illuminating unpredicted cellular machineries in gonad development, germ cell production, and reproduction A Journey to Before the Beginning of Life Exploring the Unknown Developing eg...
yanivelkoubylab.com
December 22, 2025 at 7:50 PM
🥁We are recruiting PhD students/Postdocs with strong proven background in developmental/molecular/cell biology & related areas, for various projects- check out our lab website👇🏼
We offer: competitive stipends, super equipped lab, fun international team!
yanivelkoubylab.com
We offer: competitive stipends, super equipped lab, fun international team!
yanivelkoubylab.com
Reposted by Inbal Shainer 🎗️
A study from the Baier Departement, published in Nature in February 2025, has now been selected for the Nature Highlights List 2025.
Congratulations to all the researchers involved on this well-deserved recognition!
👉 Nature Highlights 2025: www.nature.com/articles/d41...
@ishainer.bsky.social
Congratulations to all the researchers involved on this well-deserved recognition!
👉 Nature Highlights 2025: www.nature.com/articles/d41...
@ishainer.bsky.social
Neurons with identical transcriptomes can have different morphologies and functions! A new study by the Baier Lab published in @nature.com shows that temporal and spatial factors expand the repertoire of genetically similar neurons: www.nature.com/articles/s41...
@ishainer.bsky.social
@ishainer.bsky.social
December 18, 2025 at 11:59 AM
A study from the Baier Departement, published in Nature in February 2025, has now been selected for the Nature Highlights List 2025.
Congratulations to all the researchers involved on this well-deserved recognition!
👉 Nature Highlights 2025: www.nature.com/articles/d41...
@ishainer.bsky.social
Congratulations to all the researchers involved on this well-deserved recognition!
👉 Nature Highlights 2025: www.nature.com/articles/d41...
@ishainer.bsky.social
Very proud to see our paper selected as one of Nature’s 2025 highlights!
@johanneskappel.bsky.social @jlarsch.bsky.social @mpiforbi.bsky.social
www.nature.com/articles/d41...
@johanneskappel.bsky.social @jlarsch.bsky.social @mpiforbi.bsky.social
www.nature.com/articles/d41...
Asteroids, antibiotics and ants: a year of remarkable science
Highlights from News & Views published in 2025.
www.nature.com
December 18, 2025 at 9:42 AM
Very proud to see our paper selected as one of Nature’s 2025 highlights!
@johanneskappel.bsky.social @jlarsch.bsky.social @mpiforbi.bsky.social
www.nature.com/articles/d41...
@johanneskappel.bsky.social @jlarsch.bsky.social @mpiforbi.bsky.social
www.nature.com/articles/d41...
Reposted by Inbal Shainer 🎗️
Very excited to share this thread on our recent paper! We show how Zebrafish integrate visual navigation signals in aligned topographic maps. Full thread below🧵
(1/n) We are excited to share our new paper in Nature Communications, by Hagar Lavian (@hlavian.bsky.social) and team, revealing how the zebrafish brain integrates visual navigation signals! www.nature.com/articles/s41...
Visual motion and landmark position align with heading direction in the zebrafish interpeduncular nucleus - Nature Communications
How are various visual signals integrated in the vertebrate brain for navigation? Here authors show that different spatial signals are topographically organized and align to one another in the zebrafi...
www.nature.com
December 4, 2025 at 8:46 AM
Very excited to share this thread on our recent paper! We show how Zebrafish integrate visual navigation signals in aligned topographic maps. Full thread below🧵
Reposted by Inbal Shainer 🎗️
(1/n) We are excited to share our new paper in Nature Communications, by Hagar Lavian (@hlavian.bsky.social) and team, revealing how the zebrafish brain integrates visual navigation signals! www.nature.com/articles/s41...
Visual motion and landmark position align with heading direction in the zebrafish interpeduncular nucleus - Nature Communications
How are various visual signals integrated in the vertebrate brain for navigation? Here authors show that different spatial signals are topographically organized and align to one another in the zebrafi...
www.nature.com
November 24, 2025 at 4:17 PM
(1/n) We are excited to share our new paper in Nature Communications, by Hagar Lavian (@hlavian.bsky.social) and team, revealing how the zebrafish brain integrates visual navigation signals! www.nature.com/articles/s41...
Reposted by Inbal Shainer 🎗️
The Trojan Horse Gene of the Marine Virus www.technion.ac.il/en/blog/arti...
The Trojan Horse Gene of the Marine Virus - הטכניון-מכון טכנולוגי לישראל
www.technion.ac.il
November 23, 2025 at 2:42 PM
The Trojan Horse Gene of the Marine Virus www.technion.ac.il/en/blog/arti...
Reposted by Inbal Shainer 🎗️
When a larval zebrafish twitches its tail, the vascular endothelium lights up with a calcium signal, mediated by Piezo1. We used to think mechanosensing in endothelial cells was about sensing blood flow, but at least in this case it's about sensing body motion.
November 14, 2025 at 8:34 PM
When a larval zebrafish twitches its tail, the vascular endothelium lights up with a calcium signal, mediated by Piezo1. We used to think mechanosensing in endothelial cells was about sensing blood flow, but at least in this case it's about sensing body motion.
Reposted by Inbal Shainer 🎗️
Viral NblA proteins negatively affect oceanic cyanobacterial photosynthesis www.nature.com/articles/s41...
this project was led by @omernadel.bsky.social and is a joint work between the labs of @bejalab.bsky.social, Debbie Lindell and Oded Kleifeld from @biologytechnion.bsky.social
this project was led by @omernadel.bsky.social and is a joint work between the labs of @bejalab.bsky.social, Debbie Lindell and Oded Kleifeld from @biologytechnion.bsky.social
the sun is shining through the clouds in the sky above the ocean
ALT: the sun is shining through the clouds in the sky above the ocean
media.tenor.com
November 12, 2025 at 4:00 PM
Viral NblA proteins negatively affect oceanic cyanobacterial photosynthesis www.nature.com/articles/s41...
this project was led by @omernadel.bsky.social and is a joint work between the labs of @bejalab.bsky.social, Debbie Lindell and Oded Kleifeld from @biologytechnion.bsky.social
this project was led by @omernadel.bsky.social and is a joint work between the labs of @bejalab.bsky.social, Debbie Lindell and Oded Kleifeld from @biologytechnion.bsky.social
Reposted by Inbal Shainer 🎗️
November 10, 2025 at 3:20 PM
Reposted by Inbal Shainer 🎗️
How does a fish know when to blend in? Scientists identified a key circuit controlling camouflage in zebrafish – from cells in the retina sensing light to nerve cells in the brain controlling the release of a hormone that pales the skin to match bright backgrounds.
www.bi.mpg.de/news/2025-11...
www.bi.mpg.de/news/2025-11...
November 10, 2025 at 3:08 PM
How does a fish know when to blend in? Scientists identified a key circuit controlling camouflage in zebrafish – from cells in the retina sensing light to nerve cells in the brain controlling the release of a hormone that pales the skin to match bright backgrounds.
www.bi.mpg.de/news/2025-11...
www.bi.mpg.de/news/2025-11...
Reposted by Inbal Shainer 🎗️
Excited to share our paper now published in Cell!
'Zebrafish use spectral information to suppress the visual background'
Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social
@cellpress.bsky.social @cp-cell.bsky.social
👇🏻
www.cell.com/cell/fulltex...
'Zebrafish use spectral information to suppress the visual background'
Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social
@cellpress.bsky.social @cp-cell.bsky.social
👇🏻
www.cell.com/cell/fulltex...
Zebrafish use spectral information to suppress the visual background
Vertebrate eyes first evolved in water, where spectral content rapidly fades with
distance. Zebrafish exploit this loss by antagonizing cone signals to suppress the
background, pointing to distance es...
www.cell.com
November 4, 2025 at 9:16 AM
Excited to share our paper now published in Cell!
'Zebrafish use spectral information to suppress the visual background'
Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social
@cellpress.bsky.social @cp-cell.bsky.social
👇🏻
www.cell.com/cell/fulltex...
'Zebrafish use spectral information to suppress the visual background'
Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social
@cellpress.bsky.social @cp-cell.bsky.social
👇🏻
www.cell.com/cell/fulltex...
Reposted by Inbal Shainer 🎗️
Now online! Zebrafish use spectral information to suppress the visual background
Zebrafish use spectral information to suppress the visual background
Vertebrate eyes first evolved in water, where spectral content rapidly fades with distance. Zebrafish exploit this loss by antagonizing cone signals to suppress the background, pointing to distance estimation—rather than color—as an ancestral cone function.
dlvr.it
November 3, 2025 at 3:59 PM
Now online! Zebrafish use spectral information to suppress the visual background
Reposted by Inbal Shainer 🎗️
Out now in @currentbiology.bsky.social led by Kaarthik A Balakrishnan: We identify medullary circuits that represent the valence of thermal stimuli and control both long-term strategies of cold-avoidance and short term hot avoidance behaviors to enable thermoregulation. www.cell.com/current-biol...
Behavioral and circuit principles of temperature gradient navigation
Behavioral thermoregulation is critical for survival across animals. Balakrishnan
and Haesemeyer discover that thermoregulatory behavior in larval zebrafish is organized
into longer-term swim modes. T...
www.cell.com
October 24, 2025 at 2:57 PM
Out now in @currentbiology.bsky.social led by Kaarthik A Balakrishnan: We identify medullary circuits that represent the valence of thermal stimuli and control both long-term strategies of cold-avoidance and short term hot avoidance behaviors to enable thermoregulation. www.cell.com/current-biol...
Reposted by Inbal Shainer 🎗️
🧠🌟🐭 Excited to share some of my postdoc work on the evolution of dexterity!
We compared deer mice evolved in forest vs prairie habitats. We found that forest mice have:
(1) more corticospinal neurons (CSNs)
(2) better hand dexterity
(3) more dexterous climbing, which is linked to CSN number🧵
We compared deer mice evolved in forest vs prairie habitats. We found that forest mice have:
(1) more corticospinal neurons (CSNs)
(2) better hand dexterity
(3) more dexterous climbing, which is linked to CSN number🧵
October 22, 2025 at 8:41 PM
🧠🌟🐭 Excited to share some of my postdoc work on the evolution of dexterity!
We compared deer mice evolved in forest vs prairie habitats. We found that forest mice have:
(1) more corticospinal neurons (CSNs)
(2) better hand dexterity
(3) more dexterous climbing, which is linked to CSN number🧵
We compared deer mice evolved in forest vs prairie habitats. We found that forest mice have:
(1) more corticospinal neurons (CSNs)
(2) better hand dexterity
(3) more dexterous climbing, which is linked to CSN number🧵
Reposted by Inbal Shainer 🎗️
I am excited to share my PhD work on head-direction cells recorded in the wild, now published in @science.org, where we recorded neurons in bats flying outdoors on an island.
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
October 16, 2025 at 6:04 PM
I am excited to share my PhD work on head-direction cells recorded in the wild, now published in @science.org, where we recorded neurons in bats flying outdoors on an island.
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
Reposted by Inbal Shainer 🎗️
Excited to share our new #biorxivpreprint:
“Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1...
We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10
“Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1...
We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10
October 15, 2025 at 4:17 PM
Excited to share our new #biorxivpreprint:
“Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1...
We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10
“Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1...
We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10
Reposted by Inbal Shainer 🎗️
Our review is out 🎉
We discuss how neural computations in the retina shape behavior, continuing the top-down tradition of Lettvin et al.'s classic bug-detector neurons
Check it out 👀 arevie.ws/46HMEjd @annualreviews.bsky.social w/ coauthors @serenariccitelli.bsky.social @annaintegrated.bsky.social
We discuss how neural computations in the retina shape behavior, continuing the top-down tradition of Lettvin et al.'s classic bug-detector neurons
Check it out 👀 arevie.ws/46HMEjd @annualreviews.bsky.social w/ coauthors @serenariccitelli.bsky.social @annaintegrated.bsky.social
October 7, 2025 at 11:39 AM
Our review is out 🎉
We discuss how neural computations in the retina shape behavior, continuing the top-down tradition of Lettvin et al.'s classic bug-detector neurons
Check it out 👀 arevie.ws/46HMEjd @annualreviews.bsky.social w/ coauthors @serenariccitelli.bsky.social @annaintegrated.bsky.social
We discuss how neural computations in the retina shape behavior, continuing the top-down tradition of Lettvin et al.'s classic bug-detector neurons
Check it out 👀 arevie.ws/46HMEjd @annualreviews.bsky.social w/ coauthors @serenariccitelli.bsky.social @annaintegrated.bsky.social
Reposted by Inbal Shainer 🎗️
“Blame your parents if you can’t pay enough attention." At least when you are a zebrafish! Our new study on attentional switching together with Kumaresh Krishnan, @paulapflitsch.bsky.social , @zwitscherarmin.bsky.social and Florian Engert is out in Science Advances:
doi.org/10.1126/scia...
doi.org/10.1126/scia...
October 3, 2025 at 9:23 PM
“Blame your parents if you can’t pay enough attention." At least when you are a zebrafish! Our new study on attentional switching together with Kumaresh Krishnan, @paulapflitsch.bsky.social , @zwitscherarmin.bsky.social and Florian Engert is out in Science Advances:
doi.org/10.1126/scia...
doi.org/10.1126/scia...
Reposted by Inbal Shainer 🎗️
Our latest study on the neurobiology of collective behavior is now posted as a preprint, led by UCSD PhD student Jo-Hsien Yu @anitajhyu.bsky.social @ucsandiego.bsky.social @danionella.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
September 30, 2025 at 7:36 PM
Our latest study on the neurobiology of collective behavior is now posted as a preprint, led by UCSD PhD student Jo-Hsien Yu @anitajhyu.bsky.social @ucsandiego.bsky.social @danionella.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...