ImmuNoah's Ark (Noe Rodriguez)
@immunoah.bsky.social
Group Leader @MRC LMB. Passionate about (neuro)immunology, the universe & every now & then some good old fashion fantasy🏳️🌈(he/him). Opinions are my own.
https://www2.mrc-lmb.cam.ac.uk/group-leaders/n-to-s/noe-rodriguez/
https://orcid.org/0000-0001-7825-5634
https://www2.mrc-lmb.cam.ac.uk/group-leaders/n-to-s/noe-rodriguez/
https://orcid.org/0000-0001-7825-5634
Reposted by ImmuNoah's Ark (Noe Rodriguez)
How is the integrated stress response terminated?
@annebertolotti.bsky.social’s group have revealed the mechanism of termination of the ISR, answering a decades-old question surrounding the ISR pathway, which is crucial to cellular homeostasis.
www2.mrc-lmb.cam.ac.uk/how-is-the-i...
#LMBReserch
@annebertolotti.bsky.social’s group have revealed the mechanism of termination of the ISR, answering a decades-old question surrounding the ISR pathway, which is crucial to cellular homeostasis.
www2.mrc-lmb.cam.ac.uk/how-is-the-i...
#LMBReserch
November 14, 2025 at 9:30 AM
How is the integrated stress response terminated?
@annebertolotti.bsky.social’s group have revealed the mechanism of termination of the ISR, answering a decades-old question surrounding the ISR pathway, which is crucial to cellular homeostasis.
www2.mrc-lmb.cam.ac.uk/how-is-the-i...
#LMBReserch
@annebertolotti.bsky.social’s group have revealed the mechanism of termination of the ISR, answering a decades-old question surrounding the ISR pathway, which is crucial to cellular homeostasis.
www2.mrc-lmb.cam.ac.uk/how-is-the-i...
#LMBReserch
Definitely not the acknowledgement I was expecting when @dannbiostda.bsky.social told me about it (tbh I was not expecting any), but you are more than welcome! 🤣🤩
Congrats on the paper!
Congrats on the paper!
November 10, 2025 at 7:21 PM
Definitely not the acknowledgement I was expecting when @dannbiostda.bsky.social told me about it (tbh I was not expecting any), but you are more than welcome! 🤣🤩
Congrats on the paper!
Congrats on the paper!
Reposted by ImmuNoah's Ark (Noe Rodriguez)
GPR34 is a splenic cDC1 receptor that is required for efferocytosis and for the cross-presentation of apoptotic cell–associated antigen to CD8 T cells @jem.org
rupress.org/jem/article/...
rupress.org/jem/article/...
November 10, 2025 at 5:59 PM
GPR34 is a splenic cDC1 receptor that is required for efferocytosis and for the cross-presentation of apoptotic cell–associated antigen to CD8 T cells @jem.org
rupress.org/jem/article/...
rupress.org/jem/article/...
I had not had a chance to read the paper until now. Now I can say it is even cooler than I had anticipated. Congrats to all the authors.
Thus: Genetic/pharmacological modulation demonstrates GPR68’s role in acid-induced colonic nociception, supporting its therapeutic potential for pain management in colitis.
November 8, 2025 at 11:55 AM
I had not had a chance to read the paper until now. Now I can say it is even cooler than I had anticipated. Congrats to all the authors.
Reposted by ImmuNoah's Ark (Noe Rodriguez)
Acid-induced pain is complex: there are LOTS of acid sensors; acid-induced pain is common in the animal kingdom, but not naked mole-rats, see @interlukein.bsky.social’s review royalsocietypublishing.org/doi/10.1098/...
November 4, 2025 at 4:49 PM
Acid-induced pain is complex: there are LOTS of acid sensors; acid-induced pain is common in the animal kingdom, but not naked mole-rats, see @interlukein.bsky.social’s review royalsocietypublishing.org/doi/10.1098/...
Reposted by ImmuNoah's Ark (Noe Rodriguez)
This is a glimpse of the cytoskeletal structures we found doing U-ExM in more than 200 species, now in Cell🤩: shorturl.at/6oHvi
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy
November 7, 2025 at 1:35 PM
This is a glimpse of the cytoskeletal structures we found doing U-ExM in more than 200 species, now in Cell🤩: shorturl.at/6oHvi
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy
Reposted by ImmuNoah's Ark (Noe Rodriguez)
LMB scientists showcased their research at the @pborostemfest.bsky.social with hands-on activities focused on the microscopic world 🔬
Read about the event here: www2.mrc-lmb.cam.ac.uk/peterborough... #LMBNews
#PeterboroughSTEMFestival
Read about the event here: www2.mrc-lmb.cam.ac.uk/peterborough... #LMBNews
#PeterboroughSTEMFestival
November 6, 2025 at 9:51 AM
LMB scientists showcased their research at the @pborostemfest.bsky.social with hands-on activities focused on the microscopic world 🔬
Read about the event here: www2.mrc-lmb.cam.ac.uk/peterborough... #LMBNews
#PeterboroughSTEMFestival
Read about the event here: www2.mrc-lmb.cam.ac.uk/peterborough... #LMBNews
#PeterboroughSTEMFestival
Reposted by ImmuNoah's Ark (Noe Rodriguez)
TODAY@16:00 CET: How do scientists make policy impact?
Go beyond data: engage with the values the motivate decisions
Join myself (EGU) & Mario Scharfbillig (EU Commission) as we explore strategies to help your message resonate with policy-makers
www.egu.eu/webinars/564...
#Science4Policy #SciComm
Go beyond data: engage with the values the motivate decisions
Join myself (EGU) & Mario Scharfbillig (EU Commission) as we explore strategies to help your message resonate with policy-makers
www.egu.eu/webinars/564...
#Science4Policy #SciComm
www.egu.eu
November 6, 2025 at 9:44 AM
TODAY@16:00 CET: How do scientists make policy impact?
Go beyond data: engage with the values the motivate decisions
Join myself (EGU) & Mario Scharfbillig (EU Commission) as we explore strategies to help your message resonate with policy-makers
www.egu.eu/webinars/564...
#Science4Policy #SciComm
Go beyond data: engage with the values the motivate decisions
Join myself (EGU) & Mario Scharfbillig (EU Commission) as we explore strategies to help your message resonate with policy-makers
www.egu.eu/webinars/564...
#Science4Policy #SciComm
Reposted by ImmuNoah's Ark (Noe Rodriguez)
AAI Member Elizabeth Delery shared a video explaining how the flu shot works and why as an immunologist, she gets her flu shot every year. Follow #ImmunologyExplained on Instagram, Facebook, or TikTok to see the full video and share it with your network!
October 30, 2025 at 12:17 PM
AAI Member Elizabeth Delery shared a video explaining how the flu shot works and why as an immunologist, she gets her flu shot every year. Follow #ImmunologyExplained on Instagram, Facebook, or TikTok to see the full video and share it with your network!
Reposted by ImmuNoah's Ark (Noe Rodriguez)
How can public engagement transform how we teach #Immunology?
Join this parallel session organised by the BSI Teaching Affinity Group at BSI Congress to explore how collaboration and lived experience enrich education & research.
Register for #BSI25: https://bit.ly/3IkxWq8
Join this parallel session organised by the BSI Teaching Affinity Group at BSI Congress to explore how collaboration and lived experience enrich education & research.
Register for #BSI25: https://bit.ly/3IkxWq8
November 5, 2025 at 11:35 AM
How can public engagement transform how we teach #Immunology?
Join this parallel session organised by the BSI Teaching Affinity Group at BSI Congress to explore how collaboration and lived experience enrich education & research.
Register for #BSI25: https://bit.ly/3IkxWq8
Join this parallel session organised by the BSI Teaching Affinity Group at BSI Congress to explore how collaboration and lived experience enrich education & research.
Register for #BSI25: https://bit.ly/3IkxWq8
Reposted by ImmuNoah's Ark (Noe Rodriguez)
A new #PainResearch paper from us at @phar.cam.ac.uk 😃 Led by Luke Paine from the Bulmer Lab, supported by @javimmunopain.bsky.social & others, & it’s all about acid; not the hallucinogenic kind, but rather H+ www.cmghjournal.org/article/S235...
GPR68, a proton-sensing GPCR, mediates acid-induced visceral nociception
Localised acidification from immune cell infiltration and heightened glycolysis contributes
to colitis pathology by activating acid-sensing receptors such as GPR68, a proton-sensing
GPCR expressed on ...
www.cmghjournal.org
November 4, 2025 at 4:49 PM
A new #PainResearch paper from us at @phar.cam.ac.uk 😃 Led by Luke Paine from the Bulmer Lab, supported by @javimmunopain.bsky.social & others, & it’s all about acid; not the hallucinogenic kind, but rather H+ www.cmghjournal.org/article/S235...
Reposted by ImmuNoah's Ark (Noe Rodriguez)
Statistical thinking is a core part of solid biological results. However, many studies still include insufficient sample sizes, have poor experimental design, or select incorrect statistical tests.
Here, the authors present ten statistical tips for cell biology
www.nature.com/articles/s41...
Here, the authors present ten statistical tips for cell biology
www.nature.com/articles/s41...
Ten essential tips for robust statistics in cell biology - Nature Cell Biology
Statistical thinking is a core part of solid, trustworthy biology. However, many studies still include insufficient sample sizes, have poor experimental design or select an incorrect statistical metho...
www.nature.com
November 4, 2025 at 7:52 PM
Statistical thinking is a core part of solid biological results. However, many studies still include insufficient sample sizes, have poor experimental design, or select incorrect statistical tests.
Here, the authors present ten statistical tips for cell biology
www.nature.com/articles/s41...
Here, the authors present ten statistical tips for cell biology
www.nature.com/articles/s41...
Reposted by ImmuNoah's Ark (Noe Rodriguez)
'When Mendel began his investigation, his first inclination was to try breeding mice of different colors. However, before his mice experiment really got going, Mendel was forced to switch the subject of his experiments to peas by a prudish bishop uncomfortable with animals having sex in the abbey.'
Origins of the Lab Mouse
How the mouse found its way from Victorian novelty to a biomedical mainstay.
www.asimov.press
November 3, 2025 at 6:25 PM
'When Mendel began his investigation, his first inclination was to try breeding mice of different colors. However, before his mice experiment really got going, Mendel was forced to switch the subject of his experiments to peas by a prudish bishop uncomfortable with animals having sex in the abbey.'
Reposted by ImmuNoah's Ark (Noe Rodriguez)
Last chance to apply - closing Nov 3rd: www.jobs.cam.ac.uk/job/52936/ Consider coming to Cambridge to work on a highly collaborative project on lung stem cells and lung disease with @labrawlins.bsky.social and @jennydickens41.bsky.social
October 31, 2025 at 4:29 PM
Last chance to apply - closing Nov 3rd: www.jobs.cam.ac.uk/job/52936/ Consider coming to Cambridge to work on a highly collaborative project on lung stem cells and lung disease with @labrawlins.bsky.social and @jennydickens41.bsky.social
NK cell definitely as a Jedi:
Travelling the Galaxy (BM to Liver and beyond)
Innately sensing the force (Receptors & antigens on other cells)
Controlling it (IFNg secretion)
Wielding a lightsaber (cytotoxic granules)
....If they embrace the dark side, immunopathology 👻
Travelling the Galaxy (BM to Liver and beyond)
Innately sensing the force (Receptors & antigens on other cells)
Controlling it (IFNg secretion)
Wielding a lightsaber (cytotoxic granules)
....If they embrace the dark side, immunopathology 👻
🎃 Happy Halloween! Ever wondered what your immune cells would wear to a costume party?
🚑 Neutrophil as an EMT: First responder on duty!
🥷 Killer T-Cell as a K-Pop Demon Hunter: Eliminating threats with precision!
What do you think each immune cell would wear for Halloween?
🚑 Neutrophil as an EMT: First responder on duty!
🥷 Killer T-Cell as a K-Pop Demon Hunter: Eliminating threats with precision!
What do you think each immune cell would wear for Halloween?
October 31, 2025 at 5:58 PM
NK cell definitely as a Jedi:
Travelling the Galaxy (BM to Liver and beyond)
Innately sensing the force (Receptors & antigens on other cells)
Controlling it (IFNg secretion)
Wielding a lightsaber (cytotoxic granules)
....If they embrace the dark side, immunopathology 👻
Travelling the Galaxy (BM to Liver and beyond)
Innately sensing the force (Receptors & antigens on other cells)
Controlling it (IFNg secretion)
Wielding a lightsaber (cytotoxic granules)
....If they embrace the dark side, immunopathology 👻
Reposted by ImmuNoah's Ark (Noe Rodriguez)
🎃 Happy Halloween! Ever wondered what your immune cells would wear to a costume party?
🚑 Neutrophil as an EMT: First responder on duty!
🥷 Killer T-Cell as a K-Pop Demon Hunter: Eliminating threats with precision!
What do you think each immune cell would wear for Halloween?
🚑 Neutrophil as an EMT: First responder on duty!
🥷 Killer T-Cell as a K-Pop Demon Hunter: Eliminating threats with precision!
What do you think each immune cell would wear for Halloween?
October 31, 2025 at 5:25 PM
🎃 Happy Halloween! Ever wondered what your immune cells would wear to a costume party?
🚑 Neutrophil as an EMT: First responder on duty!
🥷 Killer T-Cell as a K-Pop Demon Hunter: Eliminating threats with precision!
What do you think each immune cell would wear for Halloween?
🚑 Neutrophil as an EMT: First responder on duty!
🥷 Killer T-Cell as a K-Pop Demon Hunter: Eliminating threats with precision!
What do you think each immune cell would wear for Halloween?
Reposted by ImmuNoah's Ark (Noe Rodriguez)
Exciting day for the lab: our 1rst paper is officially out in @currentbiology.bsky.social 🥳 Wonderful collaboration wt @gautamdey.bsky.social showing how Cryo-ExM achieves consistent immunostaining in diverse diatoms, from the lab and the natural environment 1/n
#ProtistsOnSky
tinyurl.com/2zxaund7
#ProtistsOnSky
tinyurl.com/2zxaund7
October 31, 2025 at 3:27 PM
Exciting day for the lab: our 1rst paper is officially out in @currentbiology.bsky.social 🥳 Wonderful collaboration wt @gautamdey.bsky.social showing how Cryo-ExM achieves consistent immunostaining in diverse diatoms, from the lab and the natural environment 1/n
#ProtistsOnSky
tinyurl.com/2zxaund7
#ProtistsOnSky
tinyurl.com/2zxaund7
Reposted by ImmuNoah's Ark (Noe Rodriguez)
Now in #Science #Immunology: Hirahara lab reports activated #TH2 cells store LC-UFAs present in inflamed #lung within #lipid droplets. Subsequent catabolism via #microlipophagy induces ST2-hi effector & memory TH2 cell phenotypes, exacerbating #type2 #airway #inflammation!
#asthma #immunometabolism
#asthma #immunometabolism
Lipolysis-microlipophagy cascade regulated by adipose triglyceride lipase drives pathogenic adaptive type 2 immunity
Enzymatic and autophagic catabolism of lipid droplets after unsaturated fatty acid uptake induces pathogenic TH2 cells.
www.science.org
October 24, 2025 at 6:54 PM
Now in #Science #Immunology: Hirahara lab reports activated #TH2 cells store LC-UFAs present in inflamed #lung within #lipid droplets. Subsequent catabolism via #microlipophagy induces ST2-hi effector & memory TH2 cell phenotypes, exacerbating #type2 #airway #inflammation!
#asthma #immunometabolism
#asthma #immunometabolism
Reposted by ImmuNoah's Ark (Noe Rodriguez)
📌 Join us in our plenary seminar tomorrow, with Dr. María Mittelbrunn, from the @cbm-csic-uam.bsky.social.
🤝 Host: Dr. @analechugavieco.bsky.social (@mitotherapx-lab.bsky.social)
Register here ➡️ https://shorturl.at/Ct3vY
#AgeingResearch #AgingResearch #Immunology #Research #Seminar
🤝 Host: Dr. @analechugavieco.bsky.social (@mitotherapx-lab.bsky.social)
Register here ➡️ https://shorturl.at/Ct3vY
#AgeingResearch #AgingResearch #Immunology #Research #Seminar
October 23, 2025 at 9:02 AM
📌 Join us in our plenary seminar tomorrow, with Dr. María Mittelbrunn, from the @cbm-csic-uam.bsky.social.
🤝 Host: Dr. @analechugavieco.bsky.social (@mitotherapx-lab.bsky.social)
Register here ➡️ https://shorturl.at/Ct3vY
#AgeingResearch #AgingResearch #Immunology #Research #Seminar
🤝 Host: Dr. @analechugavieco.bsky.social (@mitotherapx-lab.bsky.social)
Register here ➡️ https://shorturl.at/Ct3vY
#AgeingResearch #AgingResearch #Immunology #Research #Seminar
Reposted by ImmuNoah's Ark (Noe Rodriguez)
We are recruiting!!! Postdoc position available in my lab to develop this exciting project with @alexfsantos2401.bsky.social advance our understanding of food allergy and oral tolerance in early life. #ILC #organoids #FoodAllergy
www.kcl.ac.uk/jobs/128585-...
www.kcl.ac.uk/jobs/128585-...
Research Associate | King's College London
www.kcl.ac.uk
October 21, 2025 at 3:03 PM
We are recruiting!!! Postdoc position available in my lab to develop this exciting project with @alexfsantos2401.bsky.social advance our understanding of food allergy and oral tolerance in early life. #ILC #organoids #FoodAllergy
www.kcl.ac.uk/jobs/128585-...
www.kcl.ac.uk/jobs/128585-...
Reposted by ImmuNoah's Ark (Noe Rodriguez)
We hiring! Please share this post with your talented ECRs
We're looking for a postdoc interested in the formation and function of tertiary lymphoid structures - project funded by Wellcome
Based at @lmcb-ucl.bsky.social at University College London
Apply here:
www.jobs.ac.uk/job/DPD418/r...
We're looking for a postdoc interested in the formation and function of tertiary lymphoid structures - project funded by Wellcome
Based at @lmcb-ucl.bsky.social at University College London
Apply here:
www.jobs.ac.uk/job/DPD418/r...
October 21, 2025 at 3:57 PM
We hiring! Please share this post with your talented ECRs
We're looking for a postdoc interested in the formation and function of tertiary lymphoid structures - project funded by Wellcome
Based at @lmcb-ucl.bsky.social at University College London
Apply here:
www.jobs.ac.uk/job/DPD418/r...
We're looking for a postdoc interested in the formation and function of tertiary lymphoid structures - project funded by Wellcome
Based at @lmcb-ucl.bsky.social at University College London
Apply here:
www.jobs.ac.uk/job/DPD418/r...
Reposted by ImmuNoah's Ark (Noe Rodriguez)
⏰ Not long left! Early bird registration for #BSI25 closes TOMORROW.
Don’t miss your chance to save. Register now and secure your place at the UK’s biggest immunology conference in Liverpool!
🔗 https://bit.ly/3IkxWq8
Don’t miss your chance to save. Register now and secure your place at the UK’s biggest immunology conference in Liverpool!
🔗 https://bit.ly/3IkxWq8
October 21, 2025 at 8:20 AM
⏰ Not long left! Early bird registration for #BSI25 closes TOMORROW.
Don’t miss your chance to save. Register now and secure your place at the UK’s biggest immunology conference in Liverpool!
🔗 https://bit.ly/3IkxWq8
Don’t miss your chance to save. Register now and secure your place at the UK’s biggest immunology conference in Liverpool!
🔗 https://bit.ly/3IkxWq8
Reposted by ImmuNoah's Ark (Noe Rodriguez)
CD8 T engage tumor cells in Ag presentation molecule-rich pockets termed CRATERs that expand & breach tumor mass from the stromal compartment, as major site of tumor killing during treatment @cellcellpress.bsky.social @ayaludin.bsky.social
www.cell.com/cell/fulltex...
@bostonchildrens.bsky.social
www.cell.com/cell/fulltex...
@bostonchildrens.bsky.social
October 18, 2025 at 5:16 PM
CD8 T engage tumor cells in Ag presentation molecule-rich pockets termed CRATERs that expand & breach tumor mass from the stromal compartment, as major site of tumor killing during treatment @cellcellpress.bsky.social @ayaludin.bsky.social
www.cell.com/cell/fulltex...
@bostonchildrens.bsky.social
www.cell.com/cell/fulltex...
@bostonchildrens.bsky.social
Reposted by ImmuNoah's Ark (Noe Rodriguez)
New pre-print from @phar.cam.ac.uk & Bellefroid lab at ULB! Led by @mayadannawi.bsky.social w support from @interlukein.bsky.social & more! We investigate impact of overexpressing the zinc finger transcriptional regulator Prdm12 on sensory neuron function / joint pain. #neuroskyence #PainResearch
AAV-mediated overexpression of Prdm12 in knee-innervating afferents reduces inflammatory joint pain and neuronal hyperexcitability in mice
Inflammatory joint pain features in numerous musculoskeletal disorders that affect millions globally. The Prdm12 gene encodes a conserved zinc finger transcriptional regulator expressed selectively in...
www.biorxiv.org
October 16, 2025 at 6:29 AM
New pre-print from @phar.cam.ac.uk & Bellefroid lab at ULB! Led by @mayadannawi.bsky.social w support from @interlukein.bsky.social & more! We investigate impact of overexpressing the zinc finger transcriptional regulator Prdm12 on sensory neuron function / joint pain. #neuroskyence #PainResearch
Reposted by ImmuNoah's Ark (Noe Rodriguez)
#ICYMI, @jefferis.bsky.social’s group recently published the first complete connectome of an entire male Drosophila central nervous system with @hhmijanelia.bsky.social and other collaborators.
Read more about the work here: www.janelia.org/project-team...
#LMBintheNews 🧪🪰
Read more about the work here: www.janelia.org/project-team...
#LMBintheNews 🧪🪰
October 15, 2025 at 3:13 PM
#ICYMI, @jefferis.bsky.social’s group recently published the first complete connectome of an entire male Drosophila central nervous system with @hhmijanelia.bsky.social and other collaborators.
Read more about the work here: www.janelia.org/project-team...
#LMBintheNews 🧪🪰
Read more about the work here: www.janelia.org/project-team...
#LMBintheNews 🧪🪰