King Lab at McGill University
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ikinglab.bsky.social
King Lab at McGill University
@ikinglab.bsky.social
Mucosal Immunology lab in Montreal studying helminths, intestinal physiology and the microbiome: www.king-lab.com 🏳️‍🌈
Reposted by King Lab at McGill University
I finally got around to putting together a quick overview of what my book is all about.

youtu.be/xPt1xy4_i-o?...

#epigenetics #epigeneticsbook #epigenome
Epigenetics: History, Molecules, and Diseases -- Book overview
YouTube video by John Greally
youtu.be
January 2, 2026 at 7:26 PM
Reposted by King Lab at McGill University
@drjonlim.bsky.social & @reisesousalab.bsky.social show cDC1s & DNGR1 favor "tethered" neoantigens from F-actin proteins, trapping them in necrotic debris for better cross-presentation! Calls for prioritizing these neoantigens for cancer vaccine design #Immunotherapy www.nature.com/articles/s41...
Cross-presentation of dead cell-associated antigens shapes the neoantigenic landscape of tumor immunity - Nature Immunology
Here the authors show DNGR-1 expressed by cDC1s promotes CD8⁺ T cell priming to cytoskeletal neoantigens from dying tumor cells, thereby shaping cancer immune visibility and tumor evolution through im...
www.nature.com
January 2, 2026 at 7:19 PM
Reposted by King Lab at McGill University
My main PhD paper is finally out! 🎉

After ~5 years, it’s published today in 𝘕𝘢𝘵𝘶𝘳𝘦 𝘐𝘮𝘮𝘶𝘯𝘰𝘭𝘰𝘨𝘺.
@natimmunol.nature.com

It all started with an unexpected observation 🔍:
👉 Mice lacking the dendritic cell receptor DNGR-1 developed tumours earlier ⏩ and more frequently 📈 than wild-type mice.

1/11 🧵
January 2, 2026 at 4:57 PM
Reposted by King Lab at McGill University
The @nytimes.com Lost Science series continues. Here's my Q&A with a scientist who was studying how wildfire smoke threatens human health when the EPA decided that her research was no longer a funding priority. Gift link: nyti.ms/4jhpw14
December 27, 2025 at 5:11 PM
Reposted by King Lab at McGill University
Reposted by King Lab at McGill University
Need more info before signing petition for state-backed research institute? Get the full behind-the-scenes 🎞️ of how the Empire Biomedical Research Institute proposal came to be, what’s needed to move it forward, and how other states can follow suit: keypoint.keystonesymposia.org/home/shruti-...
December 18, 2025 at 9:23 PM
Was a great year for our Centre and very much looking forward to developing new microbiome projects and collaborations in 2026!
December 18, 2025 at 8:15 PM
Reposted by King Lab at McGill University
Reaching maturity: Thymic γδ T cell differentiation in mice and humans

#gdTcells
Reaching maturity: Thymic γδ T cell differentiation in mice and humans
γδ T cell differentiation into specialized effector subsets during both early life and adulthood is reviewed.
www.science.org
December 13, 2025 at 11:43 AM
Reposted by King Lab at McGill University
Today, we see the fruit of 5+ years of teamwork. We have built a map of the neutrophil compartment (mostly in mice - but also humans). It provides a biological structure that focuses on a single immune cell lineage to discover the many ways in which neutrophils "interpret" physiology.
I’m thrilled to introduce you to the NeuMap! our latest work in@nature.com. A global, comprehensive, single-cell transcriptional atlas of neutrophils across 47 biological conditions in human and mice. A real tour de force www.nature.com/articles/s41...
Architecture of the neutrophil compartment - Nature
Mapping of the neutrophil compartment using single-cell transcriptional data from multiple physiological and patological states reveals its organizational architecture and how cell state dynamics and ...
www.nature.com
December 3, 2025 at 6:57 PM
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NYC Postdocs: Join us for our next Postdoc Night Science session to practice how to get new ideas using "puzzle-switching"! This time we're in Columbia U. on Dec 3 at 5pm.
Free registration: docs.google.com/forms/d/1onf... @stearnslab.bsky.social @kelseymonson.bsky.social @jaeseunghahn.bsky.social
November 23, 2025 at 6:29 PM
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Another banger from the @harriswang.bsky.social Lab this month!

“Fecal exfoliome sequencing captures immune dynamics of the healthy and inflamed gut” www.nature.com/articles/s41...
Fecal exfoliome sequencing captures immune dynamics of the healthy and inflamed gut - Nature Biotechnology
Profiling host RNA shed in feces reveals disease states in the gut.
www.nature.com
November 18, 2025 at 12:59 AM
Reposted by King Lab at McGill University
So so grateful to all donors and to the fantastic TFRI team!
Thanks to the incredible generosity of our donors, $14.5 million in new funding has just been announced through the @terryfoxresearch.bsky.social's 2025 Terry Fox New Frontiers Program Project Grants (PPGs). Learn more: www.tfri.ca/updates/news...
October 29, 2025 at 10:27 AM
Reposted by King Lab at McGill University
Reposted by King Lab at McGill University
📚NEW #gdTcell PAPER ALERT! 'Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling' is now out in @mucosalimmunol.bsky.social! #gastrosky #GIsky #IBDsky Join us for a Bluetorial 🧵...
Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling
Intraepithelial lymphocytes expressing the γδ T cell receptor (γδ IEL) provide continuous surveillance of the intestinal epithelium. We report that mi…
www.sciencedirect.com
August 7, 2025 at 9:36 PM
Reposted by King Lab at McGill University
👇🏻👇🏻
October 17, 2025 at 2:15 PM
Reposted by King Lab at McGill University
Excited to share our review on Thetis cells and dendritic cells, and their roles in mucosal immunity and tolerance @natimmunol.nature.com rdcu.be/eLtB1
Antigen-presenting cells as arbiters of mucosal tolerance and immunity
Nature Immunology - Brown and colleagues review the heterogeneity of mucosal antigen-presenting cells that orchestrate T cell immunity to intestinal antigens.
urldefense.com
October 17, 2025 at 12:22 PM
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The Zwick Lab website is live! 🔬🌀🌈
Check out our research and team at www.zwicklab.org
Home - Zwick Lab
Our organs don’t just grow once – they grow with us. While some are more adaptable than others, many remodel throughout life to meet the body’s changing needs, from daily challenges to the extraordina...
www.zwicklab.org
October 16, 2025 at 8:27 PM
Reposted by King Lab at McGill University
Reposted by King Lab at McGill University
Happy to share that my first first-authored paper is finally out in @mucosalimmunol.bsky.social in time for the long weekend!
This work would not have been possible without the current and past members of @theonlylabever.bsky.social
Check it out here:
www.sciencedirect.com/science/arti...
ScienceDirect.com | Science, health and medical journals, full text articles and books.
authors.elsevier.com
October 10, 2025 at 9:15 PM
Reposted by King Lab at McGill University
In our latest work we've explored associations between the fecal bile acid pool and helminth infection status in school aged children in Uganda. Have a read and see what we found!
July 16, 2025 at 2:43 AM
Reposted by King Lab at McGill University
Delighted to share my latest publication as a PhD candidate in @drlarey.bsky.social’s lab at @uvicscience.bsky.social!
With our international collaborators we’re excited to share our findings on the associations between #helminths and fecal bile acids! 🪱

doi.org/10.1038/s415...
Associations between helminth infection status and the composition and concentration of fecal bile acids in school-age children in Uganda - Scientific Reports
Scientific Reports - Associations between helminth infection status and the composition and concentration of fecal bile acids in school-age children in Uganda
doi.org
July 15, 2025 at 8:44 PM
Reposted by King Lab at McGill University
Immunotherapy researcher Miriam Merad from Icahn Mount Sinai says the reason that cancer research has slowed is because of funding issues, which is something taxpayers don’t have to accept.

“We fight for patients, we fight for science, and we have to fight for progress.”
#STATSummit
October 15, 2025 at 8:36 PM
Reposted by King Lab at McGill University
Excited to see the PhD work led by Sarah Danchuk published today. Virulence hierarchies within the Mycobacterium tuberculosis complex. Thanks to all the authors and collaborators, and especially kudos to Sarah: www.pnas.org/doi/10.1073/...
https://pnas.org/doi/10.1073/pn…
October 16, 2025 at 6:39 PM
Reposted by King Lab at McGill University
SMI member Valerie Abadie reviews gut mucosal immune responses and their implications for celiac disease and food allergy at Seminars in Immunology: www.sciencedirect.com/science/arti...

#SMIMemberPaper #MucosalImmunology #Immunology
Gut mucosal immune responses – Implications for celiac disease and food allergy
The intestinal mucosa employs a diverse set of defense mechanisms—from mucosal barrier regulation to immunoregulatory pathways—to maintain homeostasis…
www.sciencedirect.com
October 9, 2025 at 2:32 PM