Hari Kalidindi
@harikalidindi.bsky.social
Postdoctoral researcher, Sensorimotor & Computational Neuroscience @UCLouvain | Studying how brain produces movements
Reposted by Hari Kalidindi
This work is so, so good. Really elegant demonstration of why low-dimensional neural dynamics in movement may follow from simple control principles. Highly complementary to arguments from Peiran Gao and @suryaganguli.bsky.social.
Fred Crevecoeur
@fredericcrevec1
🚨preprint time by @harikalidindi.bsky.social
for our work on neural population dynamics: we show that features of neural population activity during reaching emerge from a simple linear body-network system 🧵👇
biorxiv.org/content/10.1...
@fredericcrevec1
🚨preprint time by @harikalidindi.bsky.social
for our work on neural population dynamics: we show that features of neural population activity during reaching emerge from a simple linear body-network system 🧵👇
biorxiv.org/content/10.1...
November 13, 2025 at 7:35 PM
This work is so, so good. Really elegant demonstration of why low-dimensional neural dynamics in movement may follow from simple control principles. Highly complementary to arguments from Peiran Gao and @suryaganguli.bsky.social.
Reposted by Hari Kalidindi
Reposted by Hari Kalidindi
July 12, 2025 at 7:36 PM
Reposted by Hari Kalidindi
1/3) This may be a very important paper, it suggests that there are no prediction error encoding neurons in sensory areas of cortex:
www.biorxiv.org/content/10.1...
I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction.
But...
🧠📈 🧪
www.biorxiv.org/content/10.1...
I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction.
But...
🧠📈 🧪
Sensory responses of visual cortical neurons are not prediction errors
Predictive coding is theorized to be a ubiquitous cortical process to explain sensory responses. It asserts that the brain continuously predicts sensory information and imposes those predictions on lo...
www.biorxiv.org
July 11, 2025 at 3:45 PM
1/3) This may be a very important paper, it suggests that there are no prediction error encoding neurons in sensory areas of cortex:
www.biorxiv.org/content/10.1...
I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction.
But...
🧠📈 🧪
www.biorxiv.org/content/10.1...
I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction.
But...
🧠📈 🧪
Reposted by Hari Kalidindi
When we reach for an object, we adapt to unexpected dynamics and respond to disturbances. These two mechanisms work online, and when you perturb them at the right time, you can see interference...
Full story ➡️ www.biorxiv.org/content/10.1...
Full story ➡️ www.biorxiv.org/content/10.1...
Interference between flexible and adaptive reaching control
Humans rapidly update the control of an ongoing movement following changes in contextual parameters. This involves adjusting the controller to exploit redundancy in the movement goal, such as when rea...
www.biorxiv.org
July 1, 2025 at 7:45 AM
When we reach for an object, we adapt to unexpected dynamics and respond to disturbances. These two mechanisms work online, and when you perturb them at the right time, you can see interference...
Full story ➡️ www.biorxiv.org/content/10.1...
Full story ➡️ www.biorxiv.org/content/10.1...
Reposted by Hari Kalidindi
Hot take: I like a lot of research on "digital twins" but I think it's kind of a lame name for a cognitive model!
I'm sorry I didn't say that in my paper: osf.io/preprints/ps...
I'm sorry I didn't say that in my paper: osf.io/preprints/ps...
OSF
osf.io
July 8, 2025 at 4:19 AM
Hot take: I like a lot of research on "digital twins" but I think it's kind of a lame name for a cognitive model!
I'm sorry I didn't say that in my paper: osf.io/preprints/ps...
I'm sorry I didn't say that in my paper: osf.io/preprints/ps...
Reposted by Hari Kalidindi
This is fun - to make RL models more like mice in the paths they select, you gotta give them the fear of death:
arxiv.org/abs/2505.12204
🧠📈 🧪
arxiv.org/abs/2505.12204
🧠📈 🧪
Of Mice and Machines: A Comparison of Learning Between Real World Mice and RL Agents
Recent advances in reinforcement learning (RL) have demonstrated impressive capabilities in complex decision-making tasks. This progress raises a natural question: how do these artificial systems comp...
arxiv.org
June 30, 2025 at 7:08 PM
This is fun - to make RL models more like mice in the paths they select, you gotta give them the fear of death:
arxiv.org/abs/2505.12204
🧠📈 🧪
arxiv.org/abs/2505.12204
🧠📈 🧪
Reposted by Hari Kalidindi
🚨PhD position alert!🚨
Joint PhD position with @fedemar.bsky.social @predictivebrain.bsky.social and Sonja Kotz, to investigate the neurobiological underpinnings of perceptual decisions
vacancies.maastrichtuniversity.nl/job/Maastric...
Please share and if you have questions, send me a message!
Joint PhD position with @fedemar.bsky.social @predictivebrain.bsky.social and Sonja Kotz, to investigate the neurobiological underpinnings of perceptual decisions
vacancies.maastrichtuniversity.nl/job/Maastric...
Please share and if you have questions, send me a message!
PhD position in biological foundations of neural control
PhD position in biological foundations of neural control
vacancies.maastrichtuniversity.nl
June 2, 2025 at 7:27 AM
🚨PhD position alert!🚨
Joint PhD position with @fedemar.bsky.social @predictivebrain.bsky.social and Sonja Kotz, to investigate the neurobiological underpinnings of perceptual decisions
vacancies.maastrichtuniversity.nl/job/Maastric...
Please share and if you have questions, send me a message!
Joint PhD position with @fedemar.bsky.social @predictivebrain.bsky.social and Sonja Kotz, to investigate the neurobiological underpinnings of perceptual decisions
vacancies.maastrichtuniversity.nl/job/Maastric...
Please share and if you have questions, send me a message!
Reposted by Hari Kalidindi
Huh. Looks like Plato was right.
A new paper shows all language models converge on the same "universal geometry" of meaning. Researchers can translate between ANY model's embeddings without seeing the original text.
Implications for philosophy and vector databases alike. arxiv.org/pdf/2505.12540
A new paper shows all language models converge on the same "universal geometry" of meaning. Researchers can translate between ANY model's embeddings without seeing the original text.
Implications for philosophy and vector databases alike. arxiv.org/pdf/2505.12540
May 23, 2025 at 2:44 AM
Huh. Looks like Plato was right.
A new paper shows all language models converge on the same "universal geometry" of meaning. Researchers can translate between ANY model's embeddings without seeing the original text.
Implications for philosophy and vector databases alike. arxiv.org/pdf/2505.12540
A new paper shows all language models converge on the same "universal geometry" of meaning. Researchers can translate between ANY model's embeddings without seeing the original text.
Implications for philosophy and vector databases alike. arxiv.org/pdf/2505.12540
Reposted by Hari Kalidindi
Does publishing serve science or is science serving publishing?
Damian Pattinson and I (@elife.bsky.social) argue scientific publishing has evolved into a system that, rather than facilitate scholarly communication, distorts and dictates it.
onlinelibrary.wiley.com/doi/10.1002/...
#OpenScience
Damian Pattinson and I (@elife.bsky.social) argue scientific publishing has evolved into a system that, rather than facilitate scholarly communication, distorts and dictates it.
onlinelibrary.wiley.com/doi/10.1002/...
#OpenScience
May 19, 2025 at 2:52 PM
Does publishing serve science or is science serving publishing?
Damian Pattinson and I (@elife.bsky.social) argue scientific publishing has evolved into a system that, rather than facilitate scholarly communication, distorts and dictates it.
onlinelibrary.wiley.com/doi/10.1002/...
#OpenScience
Damian Pattinson and I (@elife.bsky.social) argue scientific publishing has evolved into a system that, rather than facilitate scholarly communication, distorts and dictates it.
onlinelibrary.wiley.com/doi/10.1002/...
#OpenScience
Reposted by Hari Kalidindi
New preprint from the lab, led by grad student Brandon Pratt, on the encoding properties and sensorimotor function of proprioceptive limit detectors (ie, hair plates) in the fly leg.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
May 19, 2025 at 1:44 PM
New preprint from the lab, led by grad student Brandon Pratt, on the encoding properties and sensorimotor function of proprioceptive limit detectors (ie, hair plates) in the fly leg.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Hari Kalidindi
@pessoabrain.bsky.social drops knowledge on us. Neuron spiking is highly coordinated. Waves of electric field influences are a great way to do that.
The brain is much less like a machine than it is like the murmurations of a flock of starlings
aeon.co/essays/how-t...
#neuroscience
The brain is much less like a machine than it is like the murmurations of a flock of starlings
aeon.co/essays/how-t...
#neuroscience
How the human brain is like a murmuration of starlings | Aeon Essays
The brain is much less like a machine than it is like the murmurations of a flock of starlings or an orchestral symphony
aeon.co
May 19, 2025 at 11:32 AM
@pessoabrain.bsky.social drops knowledge on us. Neuron spiking is highly coordinated. Waves of electric field influences are a great way to do that.
The brain is much less like a machine than it is like the murmurations of a flock of starlings
aeon.co/essays/how-t...
#neuroscience
The brain is much less like a machine than it is like the murmurations of a flock of starlings
aeon.co/essays/how-t...
#neuroscience
Reposted by Hari Kalidindi
🧠What do random neural networks have in common with the motor cortex?
Turns out, a lot!
Both exhibit similar low‑dimensional dynamics across sensorimotor tasks.👇🧵
Turns out, a lot!
Both exhibit similar low‑dimensional dynamics across sensorimotor tasks.👇🧵
May 15, 2025 at 12:07 PM
🧠What do random neural networks have in common with the motor cortex?
Turns out, a lot!
Both exhibit similar low‑dimensional dynamics across sensorimotor tasks.👇🧵
Turns out, a lot!
Both exhibit similar low‑dimensional dynamics across sensorimotor tasks.👇🧵
Reposted by Hari Kalidindi
A fantastic paper linking control theory with neural networks! Congrats Hari and Frec
I am very happy to share our work with
@fredcrevecoeur.bsky.social
Here, we move away from the complexity of training a neural network and ask - what minimal ingredients produce motor‑cortex-style dynamics?
t.co/MkLJcrzZdm
@fredcrevecoeur.bsky.social
Here, we move away from the complexity of training a neural network and ask - what minimal ingredients produce motor‑cortex-style dynamics?
t.co/MkLJcrzZdm
https://www.biorxiv.org/content/10.1101/2025.05.15.654192v1
t.co
May 15, 2025 at 4:33 PM
A fantastic paper linking control theory with neural networks! Congrats Hari and Frec
Reposted by Hari Kalidindi
I have seen folks waste so much time by not properly planning research. Missed literature, missing controls, ignored hypotheses, etc. Lack of planning also produces bad science (e.g. analysis until significant). So I am writing an app. Looking for feedback. scientific-paper-planner-test.vercel.app
Scientific Paper Planner
Scientific Paper Planner Application
scientific-paper-planner-test.vercel.app
May 15, 2025 at 2:28 PM
I have seen folks waste so much time by not properly planning research. Missed literature, missing controls, ignored hypotheses, etc. Lack of planning also produces bad science (e.g. analysis until significant). So I am writing an app. Looking for feedback. scientific-paper-planner-test.vercel.app
Reposted by Hari Kalidindi
Fred Crevecoeur
@fredericcrevec1
🚨preprint time by @harikalidindi.bsky.social
for our work on neural population dynamics: we show that features of neural population activity during reaching emerge from a simple linear body-network system 🧵👇
biorxiv.org/content/10.1...
@fredericcrevec1
🚨preprint time by @harikalidindi.bsky.social
for our work on neural population dynamics: we show that features of neural population activity during reaching emerge from a simple linear body-network system 🧵👇
biorxiv.org/content/10.1...
May 15, 2025 at 2:17 PM
Fred Crevecoeur
@fredericcrevec1
🚨preprint time by @harikalidindi.bsky.social
for our work on neural population dynamics: we show that features of neural population activity during reaching emerge from a simple linear body-network system 🧵👇
biorxiv.org/content/10.1...
@fredericcrevec1
🚨preprint time by @harikalidindi.bsky.social
for our work on neural population dynamics: we show that features of neural population activity during reaching emerge from a simple linear body-network system 🧵👇
biorxiv.org/content/10.1...
🧠What do random neural networks have in common with the motor cortex?
Turns out, a lot!
Both exhibit similar low‑dimensional dynamics across sensorimotor tasks.👇🧵
Turns out, a lot!
Both exhibit similar low‑dimensional dynamics across sensorimotor tasks.👇🧵
May 15, 2025 at 12:07 PM
🧠What do random neural networks have in common with the motor cortex?
Turns out, a lot!
Both exhibit similar low‑dimensional dynamics across sensorimotor tasks.👇🧵
Turns out, a lot!
Both exhibit similar low‑dimensional dynamics across sensorimotor tasks.👇🧵
Reposted by Hari Kalidindi
Amazing #cosyne25 @cosynemeeting.bsky.social Lots of feedback, tons of idea, wonderful exchanges !! @harikalidindi.bsky.social
April 2, 2025 at 11:10 AM
Amazing #cosyne25 @cosynemeeting.bsky.social Lots of feedback, tons of idea, wonderful exchanges !! @harikalidindi.bsky.social
Reposted by Hari Kalidindi
(1/5) Excited to share my work with @engeltatiana.bsky.social , out now in Nat Neuro! We show that RNNs use low-d latent circuit mechanisms for cognitive tasks. We find that context-dependent decisions in both RNNs and PFC arise from latent inhibitory mechanisms. www.nature.com/articles/s41...
Latent circuit inference from heterogeneous neural responses during cognitive tasks - Nature Neuroscience
The latent circuit model identifies low-dimensional mechanisms of task execution from heterogenous neural responses. This approach reveals a latent inhibitory mechanism for context-dependent decisions...
www.nature.com
February 12, 2025 at 6:16 PM
(1/5) Excited to share my work with @engeltatiana.bsky.social , out now in Nat Neuro! We show that RNNs use low-d latent circuit mechanisms for cognitive tasks. We find that context-dependent decisions in both RNNs and PFC arise from latent inhibitory mechanisms. www.nature.com/articles/s41...
Reposted by Hari Kalidindi
DAY 24: Advent of Comp Neuro 🎄🤖🧠🧪
Top-down inputs can select and amplify certain sensory inputs while suppressing others! Orthogonalization for the win!
“Early selection of task-relevant features through population gating”
@jbarbosa.org et al
www.nature.com/articles/s41...
Top-down inputs can select and amplify certain sensory inputs while suppressing others! Orthogonalization for the win!
“Early selection of task-relevant features through population gating”
@jbarbosa.org et al
www.nature.com/articles/s41...
December 24, 2024 at 12:12 PM
DAY 24: Advent of Comp Neuro 🎄🤖🧠🧪
Top-down inputs can select and amplify certain sensory inputs while suppressing others! Orthogonalization for the win!
“Early selection of task-relevant features through population gating”
@jbarbosa.org et al
www.nature.com/articles/s41...
Top-down inputs can select and amplify certain sensory inputs while suppressing others! Orthogonalization for the win!
“Early selection of task-relevant features through population gating”
@jbarbosa.org et al
www.nature.com/articles/s41...
Reposted by Hari Kalidindi
For those of us who are not professional biologists, it can be daunting to hear about transcription factors, signaling pathways and non-coding RNA. But this poignant piece from @philipcball.bsky.social opened my eyes to how deep and essential these ideas truly are. nautil.us/how-life-rea...
How Life Really Works
Just as I uncovered a new way to understand life, I got news about my own.
nautil.us
December 24, 2024 at 1:05 PM
For those of us who are not professional biologists, it can be daunting to hear about transcription factors, signaling pathways and non-coding RNA. But this poignant piece from @philipcball.bsky.social opened my eyes to how deep and essential these ideas truly are. nautil.us/how-life-rea...
Reposted by Hari Kalidindi
In our preprint we show that expectations about future sensory inputs shape neural population dynamics in motor circuits, supporting the idea that movement is governed by the sophisticated manipulation of sensory feedback.
https://www.biorxiv.org/content/10.1101/2024.12.22.629295v1
2/
https://www.biorxiv.org/content/10.1101/2024.12.22.629295v1
2/
Sensory expectations shape neural population dynamics in motor circuits
The neural basis of movement preparation has been extensively studied during self-initiated actions where motor cortical activity during preparation shows a lawful relationship to the parameters of…
www.biorxiv.org
December 23, 2024 at 1:00 PM
In our preprint we show that expectations about future sensory inputs shape neural population dynamics in motor circuits, supporting the idea that movement is governed by the sophisticated manipulation of sensory feedback.
https://www.biorxiv.org/content/10.1101/2024.12.22.629295v1
2/
https://www.biorxiv.org/content/10.1101/2024.12.22.629295v1
2/
Reposted by Hari Kalidindi
Can the motor system use sensory expectations to prepare for unexpected events?
Excited to share my latest work with @andpru.bsky.social – where we establish that sensory expectations shape neural population dynamics in motor circuits!
🧵 and paper below
1/
Excited to share my latest work with @andpru.bsky.social – where we establish that sensory expectations shape neural population dynamics in motor circuits!
🧵 and paper below
1/
December 23, 2024 at 1:00 PM
Can the motor system use sensory expectations to prepare for unexpected events?
Excited to share my latest work with @andpru.bsky.social – where we establish that sensory expectations shape neural population dynamics in motor circuits!
🧵 and paper below
1/
Excited to share my latest work with @andpru.bsky.social – where we establish that sensory expectations shape neural population dynamics in motor circuits!
🧵 and paper below
1/
Reposted by Hari Kalidindi
What is or isn't a "BCI"?
We argue in Nature BME today that if the tech stimulates or records brain activity AND does computation, it's a BCI.
www.nature.com/articles/s41...
But we still need a way to discuss different types of BCI separately... 🧵
#BCI #BrainComputerInterface
We argue in Nature BME today that if the tech stimulates or records brain activity AND does computation, it's a BCI.
www.nature.com/articles/s41...
But we still need a way to discuss different types of BCI separately... 🧵
#BCI #BrainComputerInterface
An application-based taxonomy for brain–computer interfaces - Nature Biomedical Engineering
Naming brain–computer interfaces according to their intended application will assist stakeholders in the evaluation of the benefits and risks of neurotechnologies.
www.nature.com
December 23, 2024 at 4:04 PM
What is or isn't a "BCI"?
We argue in Nature BME today that if the tech stimulates or records brain activity AND does computation, it's a BCI.
www.nature.com/articles/s41...
But we still need a way to discuss different types of BCI separately... 🧵
#BCI #BrainComputerInterface
We argue in Nature BME today that if the tech stimulates or records brain activity AND does computation, it's a BCI.
www.nature.com/articles/s41...
But we still need a way to discuss different types of BCI separately... 🧵
#BCI #BrainComputerInterface
Reposted by Hari Kalidindi
Here @sresch.bsky.social and I respond to a Latash piece on definitions in biological motor control. Our view: let's not caught up in prosecuting definitions -- we're in the meat of the discovery stage. doi.org/10.1123/mc.2...
Terms Are Tools in Biological Motor Control
"Terms Are Tools in Biological Motor Control" published on 23 Dec 2024 by Human Kinetics.
doi.org
December 23, 2024 at 6:03 PM
Here @sresch.bsky.social and I respond to a Latash piece on definitions in biological motor control. Our view: let's not caught up in prosecuting definitions -- we're in the meat of the discovery stage. doi.org/10.1123/mc.2...