Hari Kalidindi
harikalidindi.bsky.social
Hari Kalidindi
@harikalidindi.bsky.social
Postdoctoral researcher, Sensorimotor & Computational Neuroscience @UCLouvain | Studying how brain produces movements
Thank you so much for the compliment! Indeed, we also think it aligns well with Gao&Ganguli's theory, while highlighting the role of state-feedback control in low-D dynamics. We have updated the preprint to include more comparisons with M1 recordings.

www.biorxiv.org/content/10.1...
A model of neural population dynamics for flexible sensorimotor control
Modern large-scale recordings have revealed that motor cortex activity during reaching follows low-dimensional dynamics, thought to reflect sensorimotor computations underlying muscle activation. Howe...
www.biorxiv.org
November 14, 2025 at 10:24 AM
Thanks a lot Josh! very encouraging to know the work is being well received!
July 12, 2025 at 4:47 PM
Thank you for your comments :) Indeed the system has to be controllable. In fact, the formulation we use is MPC (receding horizon scheme). LQR was used to resolve the control gains at each step and repeating until task ends, ensuring that the controller is sensitive to sudden changes in task demands
May 20, 2025 at 6:43 AM
Yes, it makes sense! Interconnections will reduce effective dimensions. what happens if a high D input is given, in general, is something i need to think about. You might find this article useful for when effective low ranks appear in random networks www.nature.com/articles/s41...
The low-rank hypothesis of complex systems - Nature Physics
Although using low-rank matrices is the go-to approach to model the dynamics of complex systems, its validity remains formally unconfirmed. An analysis of random networks and real-world data now sheds...
www.nature.com
May 16, 2025 at 6:42 PM
*correcting the username of my coauthor @fredcrevecoeur.bsky.social
May 16, 2025 at 5:00 PM
...though a recent preprint from @runewberg.bsky.social group looks into distance depent connectivity and in the context of spinal cord dynamics
May 16, 2025 at 4:53 PM
I didn't look into this aspect. But I'm curious to know the motivation behind it. In the current model, even if I present a high D input, the gains associated with task irrelevant info will be suppressed hence ending up with low D. But I didn't check distance dependent kernels...
May 16, 2025 at 4:52 PM
I forgot to mention above...the last result (low-rank hypothesis) in fact suggests that low dimensionality must directly follow from the low dimensionality in task and limb dynamics. Hence, low D is expected in many networks including feedforward
May 16, 2025 at 1:36 PM
Also, freezing the network gains while varying the task parameters (load level, force field, or target redundancy etc.,) did not inhibit flexibility. While gains of limb were necessary to tune motor output to task demands (2/2)
May 16, 2025 at 1:13 PM
Thank you so much :) recurrent connectivity in the random networks can influence the shape of the trajectories, but low D dynamics appear even in feedforward case due to the gain-controlled feedback (1/2)
May 16, 2025 at 1:10 PM
Thanks Kevin! your feedback on the manuscript has been super helpful :)
May 15, 2025 at 4:35 PM