Joanna Groom
@groomlab.bsky.social
Immunologist @WEHI_research. Passionate about inclusive conversations and diversity, both in and outside the Immune system. She/her
Reposted by Joanna Groom
Jacques Miller?
“It started by taking a thymus out of a mouse,” said Jo Handelsman, the director of the Wisconsin Institute for Discovery at the University of Wisconsin-Madison. “Who would have thought that would be an exciting idea for the future of medicine?”
“It started by taking a thymus out of a mouse,” said Jo Handelsman, the director of the Wisconsin Institute for Discovery at the University of Wisconsin-Madison. “Who would have thought that would be an exciting idea for the future of medicine?”
'All three awards (...) honored achievements rooted in fundamental research from decades ago. Some experts interpret the selections by the Royal Swedish Academy of Sciences as representing the importance of slow, basic science, work pursued out of a desire to better understand the world.'
Nobel Prizes This Year Offer Three Cheers for Slow Science
www.nytimes.com
October 10, 2025 at 6:54 AM
Jacques Miller?
“It started by taking a thymus out of a mouse,” said Jo Handelsman, the director of the Wisconsin Institute for Discovery at the University of Wisconsin-Madison. “Who would have thought that would be an exciting idea for the future of medicine?”
“It started by taking a thymus out of a mouse,” said Jo Handelsman, the director of the Wisconsin Institute for Discovery at the University of Wisconsin-Madison. “Who would have thought that would be an exciting idea for the future of medicine?”
Thanks @10xgenomics.bsky.social for the shout out and for making your data publicly available
Why waste precious resources ($$) to reinvent data that already exists? Cool human datasets ready to go
(Although now we have scratched the spatial itch, we may need to do more @chinweetan.bsky.social 🤔)
Why waste precious resources ($$) to reinvent data that already exists? Cool human datasets ready to go
(Although now we have scratched the spatial itch, we may need to do more @chinweetan.bsky.social 🤔)
How do cytokines tune immune helpers?
Nature Immunology study from @groomlab.bsky.social ’s lab at @wehi-research.bsky.social used @10xgenomics.bsky.social single-cell & spatial tech to map T follicular helper (TFH) cells diversity.
🔗 www.nature.com/articles/s41...
#Immunology #SpatialBiology
Nature Immunology study from @groomlab.bsky.social ’s lab at @wehi-research.bsky.social used @10xgenomics.bsky.social single-cell & spatial tech to map T follicular helper (TFH) cells diversity.
🔗 www.nature.com/articles/s41...
#Immunology #SpatialBiology
October 9, 2025 at 9:54 AM
Thanks @10xgenomics.bsky.social for the shout out and for making your data publicly available
Why waste precious resources ($$) to reinvent data that already exists? Cool human datasets ready to go
(Although now we have scratched the spatial itch, we may need to do more @chinweetan.bsky.social 🤔)
Why waste precious resources ($$) to reinvent data that already exists? Cool human datasets ready to go
(Although now we have scratched the spatial itch, we may need to do more @chinweetan.bsky.social 🤔)
Reposted by Joanna Groom
Today is the last day to make a submission! You don't have to fill in the survey l, you can just upload a letter or even a video
🫵🏻Advocate for fundamental research👊🏻
@nhmrc.bsky.social need your feedback to develop the best strategy for the future of Australian medical research
Link in the 🧵
🫵🏻Advocate for fundamental research👊🏻
@nhmrc.bsky.social need your feedback to develop the best strategy for the future of Australian medical research
Link in the 🧵
Dear Everyone, I've read the #NHMRC draft strategy and I have notes ...
So I'm going to...🧵🤔🧵😱🧵😵💫🧵🙏🧵🧵🧵
This is a repost from X because you all need to know!
#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience
@nhmrc.bsky.social
So I'm going to...🧵🤔🧵😱🧵😵💫🧵🙏🧵🧵🧵
This is a repost from X because you all need to know!
#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience
@nhmrc.bsky.social
October 7, 2025 at 11:49 PM
Today is the last day to make a submission! You don't have to fill in the survey l, you can just upload a letter or even a video
🫵🏻Advocate for fundamental research👊🏻
@nhmrc.bsky.social need your feedback to develop the best strategy for the future of Australian medical research
Link in the 🧵
🫵🏻Advocate for fundamental research👊🏻
@nhmrc.bsky.social need your feedback to develop the best strategy for the future of Australian medical research
Link in the 🧵
Reposted by Joanna Groom
Dear Everyone, I've read the #NHMRC draft strategy and I have notes ...
So I'm going to...🧵🤔🧵😱🧵😵💫🧵🙏🧵🧵🧵
This is a repost from X because you all need to know!
#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience
@nhmrc.bsky.social
So I'm going to...🧵🤔🧵😱🧵😵💫🧵🙏🧵🧵🧵
This is a repost from X because you all need to know!
#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience
@nhmrc.bsky.social
October 6, 2025 at 9:27 PM
Dear Everyone, I've read the #NHMRC draft strategy and I have notes ...
So I'm going to...🧵🤔🧵😱🧵😵💫🧵🙏🧵🧵🧵
This is a repost from X because you all need to know!
#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience
@nhmrc.bsky.social
So I'm going to...🧵🤔🧵😱🧵😵💫🧵🙏🧵🧵🧵
This is a repost from X because you all need to know!
#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience
@nhmrc.bsky.social
"Biology is messy and sometimes we need to embrace the mess"
www.nature.com/articles/s41...
Huge thanks to Amy Weinmann and Danielle Chisolm for beautifully highlighting our work and the importance of our approaches @natimmunol.nature.com
www.nature.com/articles/s41...
Huge thanks to Amy Weinmann and Danielle Chisolm for beautifully highlighting our work and the importance of our approaches @natimmunol.nature.com
TFH cell programs by pathogen and species - Nature Immunology
CD4+ T follicular helper (TFH) cells that develop in response to a range of pathogens share aspects of a common gene signature. However, cytokine environments, rather than pathogen class, shape diversity in programming potential.
www.nature.com
September 30, 2025 at 9:08 PM
"Biology is messy and sometimes we need to embrace the mess"
www.nature.com/articles/s41...
Huge thanks to Amy Weinmann and Danielle Chisolm for beautifully highlighting our work and the importance of our approaches @natimmunol.nature.com
www.nature.com/articles/s41...
Huge thanks to Amy Weinmann and Danielle Chisolm for beautifully highlighting our work and the importance of our approaches @natimmunol.nature.com
Reposted by Joanna Groom
WEHI scientists led by @groomlab.bsky.social @chinweetan.bsky.social map how Tfh cells tailor instructions based on infection type. A step toward smarter vaccines and therapies.
📄 In @natimmunol.nature.com: www.nature.com/articles/s41...
🔗 Read more: www.wehi.edu.au/news/unlocki...
📄 In @natimmunol.nature.com: www.nature.com/articles/s41...
🔗 Read more: www.wehi.edu.au/news/unlocki...
September 24, 2025 at 12:42 AM
WEHI scientists led by @groomlab.bsky.social @chinweetan.bsky.social map how Tfh cells tailor instructions based on infection type. A step toward smarter vaccines and therapies.
📄 In @natimmunol.nature.com: www.nature.com/articles/s41...
🔗 Read more: www.wehi.edu.au/news/unlocki...
📄 In @natimmunol.nature.com: www.nature.com/articles/s41...
🔗 Read more: www.wehi.edu.au/news/unlocki...
Thrilled to have our latest research @wehi-research.bsky.social published in @natimmunol.nature.com
www.nature.com/articles/s41...
This work was an outstanding partnership between talented PhD student Len Dalit (now postdoc, no 🦋) and bioinformatician @chinweetan.bsky.social
Thread below...
www.nature.com/articles/s41...
This work was an outstanding partnership between talented PhD student Len Dalit (now postdoc, no 🦋) and bioinformatician @chinweetan.bsky.social
Thread below...
Divergent cytokine and transcriptional signatures control functional T follicular helper cell heterogeneity - Nature Immunology
Dalit, Tan and colleagues provide a multiomic profile of T follicular helper (TFH) cells responses to diverse pathogens, revealing a blueprint for transcriptional flexibility and new tools to interrog...
www.nature.com
September 12, 2025 at 2:20 AM
Thrilled to have our latest research @wehi-research.bsky.social published in @natimmunol.nature.com
www.nature.com/articles/s41...
This work was an outstanding partnership between talented PhD student Len Dalit (now postdoc, no 🦋) and bioinformatician @chinweetan.bsky.social
Thread below...
www.nature.com/articles/s41...
This work was an outstanding partnership between talented PhD student Len Dalit (now postdoc, no 🦋) and bioinformatician @chinweetan.bsky.social
Thread below...
Reposted by Joanna Groom
Abstract deadline extended to Monday, June 30! And travel grants are still available to student and post-doc members. Don't miss out - REPOST to share the info with others.
Don't forget 📆 Abstract deadline for poster or oral presentations is June 18. Please repost to your network to spread the word! More info or register at seattle.cytokinesociety.org
June 25, 2025 at 6:59 PM
Abstract deadline extended to Monday, June 30! And travel grants are still available to student and post-doc members. Don't miss out - REPOST to share the info with others.
Reposted by Joanna Groom
🌏 Make your mark in Melbourne! 🌏 We are looking for innovative researchers to join WEHI as Laboratory Heads and help lead the next wave of biomedical discovery.
For more information and to apply 👇
For more information and to apply 👇
Make your future Melbourne
Lead the next wave of biomedical discovery
www.wehi.edu.au
May 15, 2025 at 7:03 AM
🌏 Make your mark in Melbourne! 🌏 We are looking for innovative researchers to join WEHI as Laboratory Heads and help lead the next wave of biomedical discovery.
For more information and to apply 👇
For more information and to apply 👇
Reposted by Joanna Groom
🧠🍔 Just 48 hours on a high-fat diet can weaken gut immunity. Our new study shows saturated fats rapidly impair ILC3s!
Proud to see this featured by
@wehi-research.bsky.social as I continue to explore these questions @monashuniversity.bsky.social with the IMI Lab!
Proud to see this featured by
@wehi-research.bsky.social as I continue to explore these questions @monashuniversity.bsky.social with the IMI Lab!
A landmark WEHI-led study has uncovered how our daily food choices are having an immediate effect on our gut health.
Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity.
www.wehi.edu.au/news/fast-fo...
Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity.
www.wehi.edu.au/news/fast-fo...
May 19, 2025 at 3:45 AM
🧠🍔 Just 48 hours on a high-fat diet can weaken gut immunity. Our new study shows saturated fats rapidly impair ILC3s!
Proud to see this featured by
@wehi-research.bsky.social as I continue to explore these questions @monashuniversity.bsky.social with the IMI Lab!
Proud to see this featured by
@wehi-research.bsky.social as I continue to explore these questions @monashuniversity.bsky.social with the IMI Lab!
Reposted by Joanna Groom
ICYMI: explore our #Immunology collection, highlighting B cells, CD8+ T cell stemness, priming and differentiation, CD4+ T cell heterogeneity, autoimmunity, lymphatic immunophysiology and innate immune signaling. 👉 rupress.org/jem/collecti...
#AAI2025
#AAI2025
May 9, 2025 at 7:15 PM
ICYMI: explore our #Immunology collection, highlighting B cells, CD8+ T cell stemness, priming and differentiation, CD4+ T cell heterogeneity, autoimmunity, lymphatic immunophysiology and innate immune signaling. 👉 rupress.org/jem/collecti...
#AAI2025
#AAI2025
Reposted by Joanna Groom
So excited to share our first neuro focused paper from the lab, we show that CXCL4 (PF4) is transported into the brain by proteoglycans within the endothelial glycocalyx and that GAG binding also mediates the pro neurogenesis effects of CXCL4. www.biorxiv.org/content/10.1...
April 28, 2025 at 7:42 AM
So excited to share our first neuro focused paper from the lab, we show that CXCL4 (PF4) is transported into the brain by proteoglycans within the endothelial glycocalyx and that GAG binding also mediates the pro neurogenesis effects of CXCL4. www.biorxiv.org/content/10.1...
Excited to have our latest research published in @jem.org this week and also highlighted by @natrevimmunol.nature.com
@wehi-research.bsky.social @benjbroom.bsky.social
@wehi-research.bsky.social @benjbroom.bsky.social
May 8, 2025 at 11:31 PM
Excited to have our latest research published in @jem.org this week and also highlighted by @natrevimmunol.nature.com
@wehi-research.bsky.social @benjbroom.bsky.social
@wehi-research.bsky.social @benjbroom.bsky.social
Thanks to @cytokinesociety.bsky.social Signals+ for highlighting our recent work @benjbroom.bsky.social @wehi-research.bsky.social
Proud to share the latest publication from ICIS Member Joanna Groom's lab @groomlab.bsky.social at WEHI: Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection signals.cytokinesociety.org/2025/04/14/b...
April 24, 2025 at 12:56 AM
Thanks to @cytokinesociety.bsky.social Signals+ for highlighting our recent work @benjbroom.bsky.social @wehi-research.bsky.social
Reposted by Joanna Groom
#WeekendRead! #InterferonFriendOrFoe!
@benjbroom.bsky.social @groomlab.bsky.social &co show @jem.org that transient type I IFN inhibition upon LCMV infection or a mRNA vaccine boosts stem-like memory CD8 T cells by altering their location within the draining lymph node, potentiating virus protection
@benjbroom.bsky.social @groomlab.bsky.social &co show @jem.org that transient type I IFN inhibition upon LCMV infection or a mRNA vaccine boosts stem-like memory CD8 T cells by altering their location within the draining lymph node, potentiating virus protection
Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection | Journal of Experimental Medicine | Rockefeller University Press
Broomfield et al. demonstrate that early type I interferon blockade alters CXCR3 chemokine regulation and cell location to promote an antigen-dependent CD8
rupress.org
March 15, 2025 at 3:03 PM
#WeekendRead! #InterferonFriendOrFoe!
@benjbroom.bsky.social @groomlab.bsky.social &co show @jem.org that transient type I IFN inhibition upon LCMV infection or a mRNA vaccine boosts stem-like memory CD8 T cells by altering their location within the draining lymph node, potentiating virus protection
@benjbroom.bsky.social @groomlab.bsky.social &co show @jem.org that transient type I IFN inhibition upon LCMV infection or a mRNA vaccine boosts stem-like memory CD8 T cells by altering their location within the draining lymph node, potentiating virus protection
Reposted by Joanna Groom
Gonna guess immunologists will regret the "precursor of exhausted" T cell name in the future.
@benjbroom.bsky.social et al. @groomlab.bsky.social show that early type I interferon blockade alters CXCR3 chemokine regulation & cell location to promote an antigen-dependent CD8+ T cell transition of precursor of exhausted T cells to stem cell–like memory CD8+ T cells rupress.org/jem/article/...
March 10, 2025 at 7:27 PM
Gonna guess immunologists will regret the "precursor of exhausted" T cell name in the future.
Very excited our work out in @jem.org “Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection”
@wehi-research.bsky.social led by talented (and determined) PhD student @benjbroom.bsky.social
Thread below.
@wehi-research.bsky.social led by talented (and determined) PhD student @benjbroom.bsky.social
Thread below.
@benjbroom.bsky.social et al. @groomlab.bsky.social show that early type I interferon blockade alters CXCR3 chemokine regulation & cell location to promote an antigen-dependent CD8+ T cell transition of precursor of exhausted T cells to stem cell–like memory CD8+ T cells rupress.org/jem/article/...
March 11, 2025 at 3:26 AM
Very excited our work out in @jem.org “Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection”
@wehi-research.bsky.social led by talented (and determined) PhD student @benjbroom.bsky.social
Thread below.
@wehi-research.bsky.social led by talented (and determined) PhD student @benjbroom.bsky.social
Thread below.
Reposted by Joanna Groom
Transient inhibition of type I IFN enhances CD8+ T cell stemness and vaccine protection @jem.org @groomlab.bsky.social @benjbroom.bsky.social
doi.org/10.1084/jem....
doi.org/10.1084/jem....
March 10, 2025 at 6:34 PM
Transient inhibition of type I IFN enhances CD8+ T cell stemness and vaccine protection @jem.org @groomlab.bsky.social @benjbroom.bsky.social
doi.org/10.1084/jem....
doi.org/10.1084/jem....
Reposted by Joanna Groom
Our paper on nurturing a #PositiveResearchCulture within your #research #team published by @wellcometrust.bsky.social gives useful tips for your lab. As well as making you a good team leader, nurturing culture pays off in building your science: 1/11
wellcomeopenresearch.org/articles/9-3...
wellcomeopenresearch.org/articles/9-3...
wellcomeopenresearch.org
January 14, 2025 at 9:55 AM
Our paper on nurturing a #PositiveResearchCulture within your #research #team published by @wellcometrust.bsky.social gives useful tips for your lab. As well as making you a good team leader, nurturing culture pays off in building your science: 1/11
wellcomeopenresearch.org/articles/9-3...
wellcomeopenresearch.org/articles/9-3...
Kicking off the new year searching for a postdoc to join our team @wehi-research.bsky.social
Apply now and spread the word
Apply now and spread the word
Research Officer
Job Title Research Officer Job Description An excellent opportunity is available for a Research Officer to join the Groom Laboratory in the Immunology Division at Australia’s pre-eminent biomedical re...
wehi.wd3.myworkdayjobs.com
January 15, 2025 at 5:41 AM
Kicking off the new year searching for a postdoc to join our team @wehi-research.bsky.social
Apply now and spread the word
Apply now and spread the word
Congratulations @jenjuno.viralvaxlab.com and team for this essential update to the field
Cue the purchase of anti-CXCR4 to increase antigen-specificity in CD4 T cell activation assays
Cue the purchase of anti-CXCR4 to increase antigen-specificity in CD4 T cell activation assays
As a first #ImmunoSky post, I’m excited to share our latest pre-print, by the fantastic Mitchell Zheng!
www.biorxiv.org/content/10.1...
Our group is interested in virus-specific CD4 T cells, which means we often use in vitro stimulations (like the AIM assay) to find our cells of interest. 🧵 1/9
www.biorxiv.org/content/10.1...
Our group is interested in virus-specific CD4 T cells, which means we often use in vitro stimulations (like the AIM assay) to find our cells of interest. 🧵 1/9
www.biorxiv.org
January 7, 2025 at 7:38 AM
Congratulations @jenjuno.viralvaxlab.com and team for this essential update to the field
Cue the purchase of anti-CXCR4 to increase antigen-specificity in CD4 T cell activation assays
Cue the purchase of anti-CXCR4 to increase antigen-specificity in CD4 T cell activation assays
Reposted by Joanna Groom
So lucky to be in a lab that does great science AND indulges in a weird photoshoot 🫶
Happy holidays!
Happy holidays!
Please enjoy the 2024 edition of our #AwkwardLabPhoto
Feel incredibly proud and privileged to work with this crew @wehi-research.bsky.social
Credits:
Creative vision and execution: @benjbroom.bsky.social
Wardrobe: @brigetteduckworth.bsky.social
Best pose (always): @raymondqin.bsky.social
Feel incredibly proud and privileged to work with this crew @wehi-research.bsky.social
Credits:
Creative vision and execution: @benjbroom.bsky.social
Wardrobe: @brigetteduckworth.bsky.social
Best pose (always): @raymondqin.bsky.social
December 19, 2024 at 6:54 AM
So lucky to be in a lab that does great science AND indulges in a weird photoshoot 🫶
Happy holidays!
Happy holidays!
Please enjoy the 2024 edition of our #AwkwardLabPhoto
Feel incredibly proud and privileged to work with this crew @wehi-research.bsky.social
Credits:
Creative vision and execution: @benjbroom.bsky.social
Wardrobe: @brigetteduckworth.bsky.social
Best pose (always): @raymondqin.bsky.social
Feel incredibly proud and privileged to work with this crew @wehi-research.bsky.social
Credits:
Creative vision and execution: @benjbroom.bsky.social
Wardrobe: @brigetteduckworth.bsky.social
Best pose (always): @raymondqin.bsky.social
December 19, 2024 at 5:51 AM
Please enjoy the 2024 edition of our #AwkwardLabPhoto
Feel incredibly proud and privileged to work with this crew @wehi-research.bsky.social
Credits:
Creative vision and execution: @benjbroom.bsky.social
Wardrobe: @brigetteduckworth.bsky.social
Best pose (always): @raymondqin.bsky.social
Feel incredibly proud and privileged to work with this crew @wehi-research.bsky.social
Credits:
Creative vision and execution: @benjbroom.bsky.social
Wardrobe: @brigetteduckworth.bsky.social
Best pose (always): @raymondqin.bsky.social
Reposted by Joanna Groom
Amanda Proudfoot Tribute Award for Advances in Chemokine Biology by a Trainee cytokinesociety.org/amanda-e-i-p... Donations are also accepted to help fund this Annual Award for those interested in Chemokine Biology. Submission Deadline is 15 May for Cytokines 2025 in Seattle @crgglasgow.bsky.social
December 17, 2024 at 3:48 PM
Amanda Proudfoot Tribute Award for Advances in Chemokine Biology by a Trainee cytokinesociety.org/amanda-e-i-p... Donations are also accepted to help fund this Annual Award for those interested in Chemokine Biology. Submission Deadline is 15 May for Cytokines 2025 in Seattle @crgglasgow.bsky.social
Incredibly exciting announcement at @wehi-research.bsky.social today
Repost / Apply (Melbourne is calling you)
Repost / Apply (Melbourne is calling you)
📢 World-leading Immunologists. The Nossal Endowed Chair of Immunology has just been announced @wehi-research.bsky.social. This is your chance to move (or return) to Australia to do ground-breaking research and join a thriving environment for discovery and translation.
WEHI - The Sir Gustav Nossal Professor of Immunology - Alumni Global
The Professor will lead transformative research into the complexities of the immune system, building on Sir Gustav Nossal’s pioneering work. By fostering a culture of scientific excellence and innovat...
alumniglobal.com
December 2, 2024 at 6:43 AM
Incredibly exciting announcement at @wehi-research.bsky.social today
Repost / Apply (Melbourne is calling you)
Repost / Apply (Melbourne is calling you)