Cyril Seillet, PhD
@seilletlab.bsky.social
Immunologist, NHMRC Fellow & Lab Head, Integrated Mucosal Immunity Lab
@MonashUni
@MonashUni
Reposted by Cyril Seillet, PhD
We're looking for a post-doc to join our team
@wehi-research.bsky.social
The project is fast paced and challenging, but its going to be a ton of fun!
Apply now and please spread the word
wehi.wd3.myworkdayjobs.com/broadbean_ex....
@wehi-research.bsky.social
The project is fast paced and challenging, but its going to be a ton of fun!
Apply now and please spread the word
wehi.wd3.myworkdayjobs.com/broadbean_ex....
Senior Research Officer
Job Title Senior Research Officer Job Description An exciting opportunity exists for a talented and commercially focused researcher with a strong interest in immunology to join the Putoczki Laboratory...
wehi.wd3.myworkdayjobs.com
June 6, 2025 at 5:32 AM
We're looking for a post-doc to join our team
@wehi-research.bsky.social
The project is fast paced and challenging, but its going to be a ton of fun!
Apply now and please spread the word
wehi.wd3.myworkdayjobs.com/broadbean_ex....
@wehi-research.bsky.social
The project is fast paced and challenging, but its going to be a ton of fun!
Apply now and please spread the word
wehi.wd3.myworkdayjobs.com/broadbean_ex....
Interesting approach from Chao Zhong’s group to dissect the role of RORgt in activated ILC3 highlighting its essential function in driving HB-EGF expression, rather than IL-22.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
RORγt is crucial for gut homeostasis by regulating the expression of HB-EGF rather than IL-22 in activated ILC3s
Li et al. show that RORγt, the ILC3 master regulator, still plays a crucial role during
the ILC3 activation phase. Although it is dispensable for ILC3 maintenance and their
IL-22 production, it is req...
www.cell.com
June 6, 2025 at 7:16 AM
Interesting approach from Chao Zhong’s group to dissect the role of RORgt in activated ILC3 highlighting its essential function in driving HB-EGF expression, rather than IL-22.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted by Cyril Seillet, PhD
Thrilled to share our latest review on how the gut microbiome connects diet to health, now published in Nature Reviews Gastro & Hepa! Honored to co-sign this piece with outstanding PIs @eranelinav.bsky.social @jfcryan.bsky.social Yolanda Sanz Mélanie Deschasaux Rebekka Lambrecht rdcu.be/epret
The gut microbiome connects nutrition and human health
Nature Reviews Gastroenterology & Hepatology - In this Review, Sanz and colleagues discuss how diet shapes the gut microbiome, the role of diet–microbiome interactions on the immune,...
rdcu.be
June 4, 2025 at 7:56 PM
Thrilled to share our latest review on how the gut microbiome connects diet to health, now published in Nature Reviews Gastro & Hepa! Honored to co-sign this piece with outstanding PIs @eranelinav.bsky.social @jfcryan.bsky.social Yolanda Sanz Mélanie Deschasaux Rebekka Lambrecht rdcu.be/epret
Reposted by Cyril Seillet, PhD
Not one, not two .... but FIVE recent papers highlighting a role for RORgt+ antigen-presenting cells in the gut in establishing tolerance to food antigens
#oraltolerance #immunosky #foodallergy
#oraltolerance #immunosky #foodallergy
RORγt+ antigen-presenting cells mediate food tolerance - Nature Reviews Immunology
Five recent papers identify the RORγt+ antigen-presenting cells that induce food-antigen-specific regulatory T cells and establish food tolerance.
www.nature.com
May 29, 2025 at 3:46 PM
Not one, not two .... but FIVE recent papers highlighting a role for RORgt+ antigen-presenting cells in the gut in establishing tolerance to food antigens
#oraltolerance #immunosky #foodallergy
#oraltolerance #immunosky #foodallergy
🎓 PhD positions available @MonashUni
Join our lab to explore how neurons and immune cells shape gut immunity!
🧬 Single-cell RNAseq
🔬 3D imaging
🧠 Neuro-immune interactions
👥 Great mentoring & collaborations
Apply now 👉 tinyurl.com/Seilletlab
Join our lab to explore how neurons and immune cells shape gut immunity!
🧬 Single-cell RNAseq
🔬 3D imaging
🧠 Neuro-immune interactions
👥 Great mentoring & collaborations
Apply now 👉 tinyurl.com/Seilletlab
Understanding the neuroimmune regulation of innate immunity | Supervisor Connect
tinyurl.com
June 2, 2025 at 6:59 AM
🎓 PhD positions available @MonashUni
Join our lab to explore how neurons and immune cells shape gut immunity!
🧬 Single-cell RNAseq
🔬 3D imaging
🧠 Neuro-immune interactions
👥 Great mentoring & collaborations
Apply now 👉 tinyurl.com/Seilletlab
Join our lab to explore how neurons and immune cells shape gut immunity!
🧬 Single-cell RNAseq
🔬 3D imaging
🧠 Neuro-immune interactions
👥 Great mentoring & collaborations
Apply now 👉 tinyurl.com/Seilletlab
Reposted by Cyril Seillet, PhD
Excited to have our latest research published in @jem.org this week and also highlighted by @natrevimmunol.nature.com
@wehi-research.bsky.social @benjbroom.bsky.social
@wehi-research.bsky.social @benjbroom.bsky.social
May 8, 2025 at 11:31 PM
Excited to have our latest research published in @jem.org this week and also highlighted by @natrevimmunol.nature.com
@wehi-research.bsky.social @benjbroom.bsky.social
@wehi-research.bsky.social @benjbroom.bsky.social
Reposted by Cyril Seillet, PhD
Excited to see our work published on @cp-immunity.bsky.social.
Also shared by a nice commentary. really like the last sentence:
“Not all fuel nourishes; some, once ignited, may burn beyond control.”
Also shared by a nice commentary. really like the last sentence:
“Not all fuel nourishes; some, once ignited, may burn beyond control.”
May 18, 2025 at 10:53 PM
Excited to see our work published on @cp-immunity.bsky.social.
Also shared by a nice commentary. really like the last sentence:
“Not all fuel nourishes; some, once ignited, may burn beyond control.”
Also shared by a nice commentary. really like the last sentence:
“Not all fuel nourishes; some, once ignited, may burn beyond control.”
Reposted by Cyril Seillet, PhD
Thrilled to share our work now published on @cp-immunity.bsky.social . Big thanks to our collaborators. Here we show that short-term High-Fat diet impairs ILC3 functions in producing IL-22 through microbiota-dependent and-independent mechanisms.
Online now: Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis
Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis
Xiong et al. report that short-term, high-fat diet exposure rapidly alters the gut microbial and immune environment, disrupting tissue homeostasis. IL-22 production by group 3 innate lymphoid cells (ILC3s) is impaired, compromising gut barrier integrity. Saturated fatty acids intrinsically suppress ILC3 function, reducing their ability to control gut inflammation.
dlvr.it
April 15, 2025 at 1:25 AM
Thrilled to share our work now published on @cp-immunity.bsky.social . Big thanks to our collaborators. Here we show that short-term High-Fat diet impairs ILC3 functions in producing IL-22 through microbiota-dependent and-independent mechanisms.
Reposted by Cyril Seillet, PhD
A landmark WEHI-led study has uncovered how our daily food choices are having an immediate effect on our gut health.
Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity.
www.wehi.edu.au/news/fast-fo...
Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity.
www.wehi.edu.au/news/fast-fo...
May 19, 2025 at 1:41 AM
A landmark WEHI-led study has uncovered how our daily food choices are having an immediate effect on our gut health.
Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity.
www.wehi.edu.au/news/fast-fo...
Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity.
www.wehi.edu.au/news/fast-fo...
🧠🍔 Just 48 hours on a high-fat diet can weaken gut immunity. Our new study shows saturated fats rapidly impair ILC3s!
Proud to see this featured by
@wehi-research.bsky.social as I continue to explore these questions @monashuniversity.bsky.social with the IMI Lab!
Proud to see this featured by
@wehi-research.bsky.social as I continue to explore these questions @monashuniversity.bsky.social with the IMI Lab!
A landmark WEHI-led study has uncovered how our daily food choices are having an immediate effect on our gut health.
Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity.
www.wehi.edu.au/news/fast-fo...
Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity.
www.wehi.edu.au/news/fast-fo...
May 19, 2025 at 3:45 AM
🧠🍔 Just 48 hours on a high-fat diet can weaken gut immunity. Our new study shows saturated fats rapidly impair ILC3s!
Proud to see this featured by
@wehi-research.bsky.social as I continue to explore these questions @monashuniversity.bsky.social with the IMI Lab!
Proud to see this featured by
@wehi-research.bsky.social as I continue to explore these questions @monashuniversity.bsky.social with the IMI Lab!