Shane Gonen
@gonenshane.bsky.social
Assistant Professor, University of California Irvine. All opinions my own #CryoEM #ProteinDesign #Biochemistry #MembraneProteins #UCI
cryoem.bio.uci.edu
cryoem.bio.uci.edu
Reposted by Shane Gonen
Our home department of Molecular Biology & Biochemistry at UC Irvine is looking to hire a new tenure-track assistant professor in the broad area of structural biology. Come be our colleague! recruit.ap.uci.edu/JPF09887
Please apply and/or share this post.
Please apply and/or share this post.
Assistant Professor in Structural Biology and Biochemistry, Department of Molecular Biology & Biochemistry
University of California, Irvine is hiring. Apply now!
recruit.ap.uci.edu
October 17, 2025 at 11:23 PM
Our home department of Molecular Biology & Biochemistry at UC Irvine is looking to hire a new tenure-track assistant professor in the broad area of structural biology. Come be our colleague! recruit.ap.uci.edu/JPF09887
Please apply and/or share this post.
Please apply and/or share this post.
Reposted by Shane Gonen
Herculean effort by the Wiles lab @UCIBioSci Congrats to the entire team and the first author postdoc Liz for this amazing cover art! Proud of #Nicholaslab members Naveena and Julio for the small role we played in this groundbreaking work
"Phollow" the link to our May issue to read about...
💥lysing bacterial pathogens
⛽microbial alkane oxidation
🌱importance of seed-borne bacteria
🙅♀️protective antibodies for norovirus
🚰E. coli in urban drinking water
...and more!👇
www.nature.com/nmicrobiol/v...
💥lysing bacterial pathogens
⛽microbial alkane oxidation
🌱importance of seed-borne bacteria
🙅♀️protective antibodies for norovirus
🚰E. coli in urban drinking water
...and more!👇
www.nature.com/nmicrobiol/v...
May 6, 2025 at 5:49 PM
Herculean effort by the Wiles lab @UCIBioSci Congrats to the entire team and the first author postdoc Liz for this amazing cover art! Proud of #Nicholaslab members Naveena and Julio for the small role we played in this groundbreaking work
Reposted by Shane Gonen
We’re thrilled to be featured on the May cover of Nature Microbiology... And our Research Briefing is out now—check it out, it’s 🔥! www.nature.com/articles/s41...
May 6, 2025 at 7:18 PM
We’re thrilled to be featured on the May cover of Nature Microbiology... And our Research Briefing is out now—check it out, it’s 🔥! www.nature.com/articles/s41...
Reposted by Shane Gonen
"Phollow" the link to our May issue to read about...
💥lysing bacterial pathogens
⛽microbial alkane oxidation
🌱importance of seed-borne bacteria
🙅♀️protective antibodies for norovirus
🚰E. coli in urban drinking water
...and more!👇
www.nature.com/nmicrobiol/v...
💥lysing bacterial pathogens
⛽microbial alkane oxidation
🌱importance of seed-borne bacteria
🙅♀️protective antibodies for norovirus
🚰E. coli in urban drinking water
...and more!👇
www.nature.com/nmicrobiol/v...
May 6, 2025 at 4:19 PM
"Phollow" the link to our May issue to read about...
💥lysing bacterial pathogens
⛽microbial alkane oxidation
🌱importance of seed-borne bacteria
🙅♀️protective antibodies for norovirus
🚰E. coli in urban drinking water
...and more!👇
www.nature.com/nmicrobiol/v...
💥lysing bacterial pathogens
⛽microbial alkane oxidation
🌱importance of seed-borne bacteria
🙅♀️protective antibodies for norovirus
🚰E. coli in urban drinking water
...and more!👇
www.nature.com/nmicrobiol/v...
Beautiful new work from our colleagues down the hall 🔬🥂
I am thrilled to share the first manuscript from the Wiles lab! We present "Phollow", an in vivo phage-tagging approach that enables direct observation of phage outbreaks with single-virion resolution by live imaging. Here some highlights 👇 www.nature.com/articles/s41...
Phollow reveals in situ phage transmission dynamics in the zebrafish gut microbiome at single-virion resolution
Nature Microbiology - ‘Phollow’ is a live imaging-based fluorescence tagging approach that can track phage replication and spread in situ with single-virion resolution.
www.nature.com
April 19, 2025 at 12:54 AM
Beautiful new work from our colleagues down the hall 🔬🥂
Our #CryoEM study on the binding of a Tarantula toxin to a full-length human voltage-gated sodium channel has been published. Very proud of the awesome people in my lab 🥳🥂
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I - Nature Communications
Animal toxins can modulate action potentials and are important leads for therapeutics. Here, the authors use cryo-EM to show the interaction of the tarantula venom peptide Protoxin-I with a human volt...
www.nature.com
February 7, 2025 at 9:01 PM
Our #CryoEM study on the binding of a Tarantula toxin to a full-length human voltage-gated sodium channel has been published. Very proud of the awesome people in my lab 🥳🥂
www.nature.com/articles/s41...
www.nature.com/articles/s41...
buckle up out there
February 1, 2025 at 9:04 PM
buckle up out there
Reposted by Shane Gonen
Groundbreaking work by @matthewkhoward.bsky.social and Nicholas Hoppe (not on bsky?) from the @willowcoyote.bsky.social @amanglik.bsky.social labs.
Mapping function to structure with deep mutational scanning to resolve the mechanisms of pH sensing GPCRs
www.sciencedirect.com/science/arti...
Mapping function to structure with deep mutational scanning to resolve the mechanisms of pH sensing GPCRs
www.sciencedirect.com/science/arti...
Molecular basis of proton sensing by G protein-coupled receptors
Three proton-sensing G protein-coupled receptors (GPCRs)—GPR4, GPR65, and GPR68—respond to extracellular pH to regulate diverse physiology. How proton…
www.sciencedirect.com
January 2, 2025 at 5:35 PM
Groundbreaking work by @matthewkhoward.bsky.social and Nicholas Hoppe (not on bsky?) from the @willowcoyote.bsky.social @amanglik.bsky.social labs.
Mapping function to structure with deep mutational scanning to resolve the mechanisms of pH sensing GPCRs
www.sciencedirect.com/science/arti...
Mapping function to structure with deep mutational scanning to resolve the mechanisms of pH sensing GPCRs
www.sciencedirect.com/science/arti...
Reposted by Shane Gonen
Ok, trying to bring my community back together... I created a starter pack for lipids and membrane protein aficionados!
Feel free to share, add and distribute, so we can come together again! 😍
go.bsky.app/AEeXh86
Feel free to share, add and distribute, so we can come together again! 😍
go.bsky.app/AEeXh86
November 16, 2024 at 3:53 AM
Ok, trying to bring my community back together... I created a starter pack for lipids and membrane protein aficionados!
Feel free to share, add and distribute, so we can come together again! 😍
go.bsky.app/AEeXh86
Feel free to share, add and distribute, so we can come together again! 😍
go.bsky.app/AEeXh86
Reposted by Shane Gonen
November 8, 2024 at 10:01 PM