Gomes Lab
@gomeslab.bsky.social
We are focused on understanding how aging and other factors that shape host physiology regulate cancer progression, evolution and treatment responses
https://lab.moffitt.org/gomes/
https://lab.moffitt.org/gomes/
Pinned
Gomes Lab
@gomeslab.bsky.social
· Jul 11
Cancer progression through the lens of age-induced metabolic reprogramming - Nature Reviews Cancer
In this Perspective, Lazure and Gomes argue that metabolic changes that occur as a result of ageing may shape tumour initiation and progression and the development of metastatic disease.
www.nature.com
Super excited to share our newest piece out today @natrevcancer.nature.com linking age-induced metabolic reprogramming to cancer development. www.nature.com/articles/s41...
So proud of Felicia Lazure, who spearheads our studies on aging and lung cancer, for her American Lung Association Catalyst Award. Thank you for the continued support of our studies @moffittnews.bsky.social #proudPI
July 25, 2025 at 3:50 PM
So proud of Felicia Lazure, who spearheads our studies on aging and lung cancer, for her American Lung Association Catalyst Award. Thank you for the continued support of our studies @moffittnews.bsky.social #proudPI
Super proud of @standrapela.bsky.social, this just cements what I have known all along, you have a bright future ahead of you! #proudPI
Grateful to @NIH for being awarded prestigious K99/R00 Pathway to Independence award. Huge thanks to @gomeslab.bsky.social and @moffittnews.bsky.social for the opportunity to further my research in a supportive environment. Excited for what’s ahead!
July 22, 2025 at 11:26 PM
Super proud of @standrapela.bsky.social, this just cements what I have known all along, you have a bright future ahead of you! #proudPI
Super excited to share our newest piece out today @natrevcancer.nature.com linking age-induced metabolic reprogramming to cancer development. www.nature.com/articles/s41...
Cancer progression through the lens of age-induced metabolic reprogramming - Nature Reviews Cancer
In this Perspective, Lazure and Gomes argue that metabolic changes that occur as a result of ageing may shape tumour initiation and progression and the development of metastatic disease.
www.nature.com
July 11, 2025 at 4:42 PM
Super excited to share our newest piece out today @natrevcancer.nature.com linking age-induced metabolic reprogramming to cancer development. www.nature.com/articles/s41...
Reposted by Gomes Lab
A big thank you to all the co-authors and collaborators on this study for their contributions to bring this to the finish line! @standrapela.bsky.social
@gomeslab.bsky.social
@jaguirreghisolab.bsky.social
And the majority not on BlueSky!
@gomeslab.bsky.social
@jaguirreghisolab.bsky.social
And the majority not on BlueSky!
May 27, 2025 at 1:39 PM
A big thank you to all the co-authors and collaborators on this study for their contributions to bring this to the finish line! @standrapela.bsky.social
@gomeslab.bsky.social
@jaguirreghisolab.bsky.social
And the majority not on BlueSky!
@gomeslab.bsky.social
@jaguirreghisolab.bsky.social
And the majority not on BlueSky!
So happy to share the newest pre-print from the lab where we show that old age significantly changes the traits that evolve in established lung adenocarcinoma. This work sheds light into the importance of modeling age-related cancers in the context of old age. www.biorxiv.org/content/10.1...
Aging directs the differential evolution of KRAS-driven lung adenocarcinoma
Lung adenocarcinoma (LUAD), the most common histological subtype of lung cancer( [1][1], [2][2] ), is a disease of the elderly, with an average age of diagnosis of about 70 years of age( [3][3] ). Old...
www.biorxiv.org
February 3, 2025 at 7:13 PM
So happy to share the newest pre-print from the lab where we show that old age significantly changes the traits that evolve in established lung adenocarcinoma. This work sheds light into the importance of modeling age-related cancers in the context of old age. www.biorxiv.org/content/10.1...
Reposted by Gomes Lab
You cannot underestimate all the positive and long-term benefits of having a supportive #mentor
One could argue this is at least as important as the research topic 🧪
Do choose wisely..
#MentoringMonth
One could argue this is at least as important as the research topic 🧪
Do choose wisely..
#MentoringMonth
January 8, 2025 at 1:07 PM
You cannot underestimate all the positive and long-term benefits of having a supportive #mentor
One could argue this is at least as important as the research topic 🧪
Do choose wisely..
#MentoringMonth
One could argue this is at least as important as the research topic 🧪
Do choose wisely..
#MentoringMonth
Reposted by Gomes Lab
🔔 We're hiring a Research Technician to join our team!
The ideal candidate will be down to work with mice and human tissues, be available to join us for at least two years, and enjoy being a part of an ambitious research team.
Apply here: correialab.com/join-the-team/
Funded by La Caixa Foundation
The ideal candidate will be down to work with mice and human tissues, be available to join us for at least two years, and enjoy being a part of an ambitious research team.
Apply here: correialab.com/join-the-team/
Funded by La Caixa Foundation
January 12, 2025 at 11:11 AM
🔔 We're hiring a Research Technician to join our team!
The ideal candidate will be down to work with mice and human tissues, be available to join us for at least two years, and enjoy being a part of an ambitious research team.
Apply here: correialab.com/join-the-team/
Funded by La Caixa Foundation
The ideal candidate will be down to work with mice and human tissues, be available to join us for at least two years, and enjoy being a part of an ambitious research team.
Apply here: correialab.com/join-the-team/
Funded by La Caixa Foundation
Happy Holidays from the Gomes Lab 🎄🎅
December 24, 2024 at 9:04 PM
Happy Holidays from the Gomes Lab 🎄🎅
Congratulations @standrapela.bsky.social, very well deserved #ProudPI
Big thanks to #ForbesCesko for spreading a word about our #AmericanCancerSociety postdoc scholar. @moffittnews.bsky.social #MoffittResearch
Full article (Czech only) here: forbes.cz/cesti-vedci-...
Full article (Czech only) here: forbes.cz/cesti-vedci-...
Čeští vědci získali v USA prestižní granty. Dozvěděli se to v úkrytu před hurikánem | Forbes
Čeští vědci Stanislav Drápela a Tomáš Zelenka z institutu Moffitt Cancer Center v americké Tampě získali nezávisle na sobě prestižní granty na výzkum proti rakovině.
forbes.cz
November 25, 2024 at 3:32 PM
Congratulations @standrapela.bsky.social, very well deserved #ProudPI
For a starter package on Cancer and Aging 👇🏻 Thanks Sandy ☺️
November 25, 2024 at 1:33 PM
For a starter package on Cancer and Aging 👇🏻 Thanks Sandy ☺️
Reposted by Gomes Lab
Join us in Boston! The Department of Molecular Metabolism (MET) at the Harvard T.H. Chan School of Public Health has just opened a Jr. Faculty search. Apply by January 15, 2025 at academicpositions.harvard.edu/postings/14371
Assistant Professor, Department of Molecular Metabolism
The Department of Molecular Metabolism (MET) at the Harvard T.H. Chan School of Public Health invites applications for the level of assistant professor. The shared interest of MET faculty is to explor...
academicpositions.harvard.edu
November 21, 2024 at 12:59 AM
Join us in Boston! The Department of Molecular Metabolism (MET) at the Harvard T.H. Chan School of Public Health has just opened a Jr. Faculty search. Apply by January 15, 2025 at academicpositions.harvard.edu/postings/14371
Reposted by Gomes Lab
new out in Nature www.nature.com/articles/s41...
Normal breast tissues harbour rare populations of aneuploid epithelial cells - Nature
Using single-cell DNA sequencing we show that most healthy women harbour rare populations of aneuploid epithelial cells with copy number alteration events in their breast tissue that expand and accumu...
www.nature.com
November 20, 2024 at 5:08 PM
new out in Nature www.nature.com/articles/s41...
So proud of our student Devesh and postdoc @standrapela.bsky.social representing our lab at #AACRtumorenviron24
November 20, 2024 at 1:48 PM
So proud of our student Devesh and postdoc @standrapela.bsky.social representing our lab at #AACRtumorenviron24
Reposted by Gomes Lab
🦋Introductory post 🦋
The Metastasis Research Society (MRS) is a professional society for metastasis researchers. The MRS is dedicated to promoting research into all aspects of metastasis, and the exchange of information amongst key stakeholders including scientists, clinicians & patients.
The Metastasis Research Society (MRS) is a professional society for metastasis researchers. The MRS is dedicated to promoting research into all aspects of metastasis, and the exchange of information amongst key stakeholders including scientists, clinicians & patients.
November 20, 2024 at 7:47 AM
🦋Introductory post 🦋
The Metastasis Research Society (MRS) is a professional society for metastasis researchers. The MRS is dedicated to promoting research into all aspects of metastasis, and the exchange of information amongst key stakeholders including scientists, clinicians & patients.
The Metastasis Research Society (MRS) is a professional society for metastasis researchers. The MRS is dedicated to promoting research into all aspects of metastasis, and the exchange of information amongst key stakeholders including scientists, clinicians & patients.
Reposted by Gomes Lab
Check out our News and views on @carman-mc-li.bsky.social cool study about the molecular regulation of Brca1 deficiency mammary oncogenesis - with Steven Lewis www.nature.com/articles/s41...
Epigenetic scars of Brca1 loss point toward breast cancer cell of origin - Nature Genetics
The two-hit hypothesis suggests that a second mutation is necessary for cancer development in cells with a defective tumor-suppressor gene, such as BRCA1. However, a study now shows that the loss of j...
www.nature.com
November 20, 2024 at 12:31 PM
Check out our News and views on @carman-mc-li.bsky.social cool study about the molecular regulation of Brca1 deficiency mammary oncogenesis - with Steven Lewis www.nature.com/articles/s41...
We had a lot of fun conceptualizing and writing this perspective. If you want to know more about metabolism and cancer dormancy check it out 👇🏻
Let’s start this bsky positively with a free full text of our @gomeslab.bsky.social and @alpcorreia.bsky.social recently published review on metabolism and dormancy. www.sciencedirect.com/science/arti...
Metabolic landscape of disseminated cancer dormancy
Cancer dormancy is a phenomenon defined by the entry of cancer cells into a reversible quiescent, nonproliferative state, and represents an essential …
www.sciencedirect.com
November 19, 2024 at 1:26 PM
We had a lot of fun conceptualizing and writing this perspective. If you want to know more about metabolism and cancer dormancy check it out 👇🏻
Reposted by Gomes Lab
Mind blowing talk by James DeGregori on viral infection, awakening, and maintenance of metastatic outgrowth. Not good news for those of us that have had multiple Covid-19 infections.
#AACRtumorenviron24
#AACRtumorenviron24
November 18, 2024 at 5:15 PM
Mind blowing talk by James DeGregori on viral infection, awakening, and maintenance of metastatic outgrowth. Not good news for those of us that have had multiple Covid-19 infections.
#AACRtumorenviron24
#AACRtumorenviron24
Super cool work from @vonmeyennlab.bsky.social www.nature.com/articles/s41...
Adipose tissue retains an epigenetic memory of obesity after weight loss - Nature
Stable epigenetic changes indicate the existence of an obesogenic memory in mouse adipocytes that primes cells for pathological responses in an obesogenic environment and potentially contributes to th...
www.nature.com
November 18, 2024 at 5:54 PM
Super cool work from @vonmeyennlab.bsky.social www.nature.com/articles/s41...
Reposted by Gomes Lab
Let's start the week at Bluesky with an updated Starter Pack V3.0 #metabolism and #mitochondrialbiology are super strong here!
go.bsky.app/VavECSX
go.bsky.app/VavECSX
November 18, 2024 at 8:13 AM
Let's start the week at Bluesky with an updated Starter Pack V3.0 #metabolism and #mitochondrialbiology are super strong here!
go.bsky.app/VavECSX
go.bsky.app/VavECSX
Super happy to share our lab new paper spearheaded by graduate student Joanne Tejero describing a role for the age-induced oncometabolite methylamlonic acid in promoting T cell exhaustion and contributing to lung cancer immune evasion. www.nature.com/articles/s41...
Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8+ T cells to suppress anti-tumor immunity - Oncogene
Oncogene - Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8+ T cells to suppress anti-tumor immunity
www.nature.com
November 16, 2024 at 2:47 PM
Super happy to share our lab new paper spearheaded by graduate student Joanne Tejero describing a role for the age-induced oncometabolite methylamlonic acid in promoting T cell exhaustion and contributing to lung cancer immune evasion. www.nature.com/articles/s41...