Reposted by Aleyah E. Goins
PhD students and Postdocs: The Night Science Podcast (@nightsciencepod.bsky.social) is producing an episode highlighting young scientists talking about their creative process. DM me if you'd like us to consider you for this, & read below what PhD student Davis Garner will contribute! ⬇️
November 23, 2025 at 12:27 AM
PhD students and Postdocs: The Night Science Podcast (@nightsciencepod.bsky.social) is producing an episode highlighting young scientists talking about their creative process. DM me if you'd like us to consider you for this, & read below what PhD student Davis Garner will contribute! ⬇️
#BookSky I have not been reading as much as I want lately so big reviews have been on hold. I finished off Haruki Murakami's Dance Dance Dance. Fun to read, it was OK. I tried Hermann Hesse's Steppenwolf. Also, just OK. Maybe it's a sign of growth these literary characters aren't packing a punch. 🤷
November 20, 2025 at 3:19 PM
#BookSky I have not been reading as much as I want lately so big reviews have been on hold. I finished off Haruki Murakami's Dance Dance Dance. Fun to read, it was OK. I tried Hermann Hesse's Steppenwolf. Also, just OK. Maybe it's a sign of growth these literary characters aren't packing a punch. 🤷
Reposting this as a reminder to check back when this book comes out 👍
Big news: I’m writing a book!!
I’ll be writing & illustrating a beginner’s guide to appreciating wildlife in cities/suburbs, & how all of us can make our neighborhoods better for those animals.
Thank you to my book agent @ericsmithrocks.bsky.social & the folks at Storey for believing in this book!
I’ll be writing & illustrating a beginner’s guide to appreciating wildlife in cities/suburbs, & how all of us can make our neighborhoods better for those animals.
Thank you to my book agent @ericsmithrocks.bsky.social & the folks at Storey for believing in this book!
November 20, 2025 at 3:14 PM
Reposting this as a reminder to check back when this book comes out 👍
Pretty exciting to develop simpler, faster ways to target specific neuronal subtypes 🤩 I'm looking forward to seeing this be expanded and integrated in future pain studies ☄️ #PainResearch #Neuroscience #DRG #FACS
Want to flow-analyze or FACS your sensory neurons without relying on reporter mice? Check out our new short report 👇https://www.biorxiv.org/content/10.1101/2025.11.19.688847v1
A novel method to sort and enrich sensory neurons
Peripheral sensory neurons, residing in the dorsal root ganglia (DRG), relay sensory information from the periphery to the central nervous system. Although single-cell transcriptomic studies have iden...
www.biorxiv.org
November 20, 2025 at 2:54 PM
Pretty exciting to develop simpler, faster ways to target specific neuronal subtypes 🤩 I'm looking forward to seeing this be expanded and integrated in future pain studies ☄️ #PainResearch #Neuroscience #DRG #FACS
Reposted by Aleyah E. Goins
Are You Cold, or Do You Have Cold? The Answer Defines Your Identity and How You Perceive the World
www.ocrampal.com/i-am-cold-vs...
#philosophy #science #psychology #AI #intelligence #physics #biology #philmind #philsci #philsky #philpsy #neurosky #neuroskyence
www.ocrampal.com/i-am-cold-vs...
#philosophy #science #psychology #AI #intelligence #physics #biology #philmind #philsci #philsky #philpsy #neurosky #neuroskyence
I Am Cold vs. I Have Cold: A Philosophy in Two Words
There's a curious linguistic asymmetry that might explain one of the deepest divides in Western philosophy. It hides in plain sight, in something as simple as how we talk about feeling cold.
The Col...
www.ocrampal.com
November 19, 2025 at 2:43 PM
Are You Cold, or Do You Have Cold? The Answer Defines Your Identity and How You Perceive the World
www.ocrampal.com/i-am-cold-vs...
#philosophy #science #psychology #AI #intelligence #physics #biology #philmind #philsci #philsky #philpsy #neurosky #neuroskyence
www.ocrampal.com/i-am-cold-vs...
#philosophy #science #psychology #AI #intelligence #physics #biology #philmind #philsci #philsky #philpsy #neurosky #neuroskyence
Reposted by Aleyah E. Goins
🎉 Join the 1st NYC Area Pain Research Meet-Up!
🗓 Fri, Dec 5 | 3–6 PM @nyupainresearch.bsky.social , 433 1st Ave, NY, NY
Don’t miss Dr. Steve Davidson’s keynote: “Humanizing Pain Neurobiology for Translational Gain” — plus great company & treats!
Registration below 👇 💫 #PainResearch
🗓 Fri, Dec 5 | 3–6 PM @nyupainresearch.bsky.social , 433 1st Ave, NY, NY
Don’t miss Dr. Steve Davidson’s keynote: “Humanizing Pain Neurobiology for Translational Gain” — plus great company & treats!
Registration below 👇 💫 #PainResearch
November 19, 2025 at 5:03 PM
🎉 Join the 1st NYC Area Pain Research Meet-Up!
🗓 Fri, Dec 5 | 3–6 PM @nyupainresearch.bsky.social , 433 1st Ave, NY, NY
Don’t miss Dr. Steve Davidson’s keynote: “Humanizing Pain Neurobiology for Translational Gain” — plus great company & treats!
Registration below 👇 💫 #PainResearch
🗓 Fri, Dec 5 | 3–6 PM @nyupainresearch.bsky.social , 433 1st Ave, NY, NY
Don’t miss Dr. Steve Davidson’s keynote: “Humanizing Pain Neurobiology for Translational Gain” — plus great company & treats!
Registration below 👇 💫 #PainResearch
Reposted by Aleyah E. Goins
The Maldives just became the first country to ban tobacco for an entire generation. Anyone born on or after Jan 1, 2007 can never buy or use tobacco — residents and tourists included.
www.empr.com/news/maldive....
www.empr.com/news/maldive....
November 14, 2025 at 1:00 AM
The Maldives just became the first country to ban tobacco for an entire generation. Anyone born on or after Jan 1, 2007 can never buy or use tobacco — residents and tourists included.
www.empr.com/news/maldive....
www.empr.com/news/maldive....
Reposted by Aleyah E. Goins
Reposted by Aleyah E. Goins
📢🔬Check out our latest study on the specific role of endocytic mediators in pain-related synaptic transmission, now out in PAIN. @mariafialho.bsky.social #PainResearch #Neuroscience #SynapticTransmission
Fialho et al. find that synaptojanin 1, endophilin A1, dynamin 1, and adaptor-associated protein kinase-1 mediate synaptic vesicle recycling and neurotransmission in nociceptive circuits in the spinal cord. Learn more in #PAIN bit.ly/3WIf08B
November 13, 2025 at 6:53 PM
📢🔬Check out our latest study on the specific role of endocytic mediators in pain-related synaptic transmission, now out in PAIN. @mariafialho.bsky.social #PainResearch #Neuroscience #SynapticTransmission
Reposted by Aleyah E. Goins
Help:
We have developed an organoid model of diabetic neuropathy.
It has oligodendrocytes, myelin, and adding diabetic stimuli makes them lose myelination, and break down mitochondria.
Further yet, we show this can be prevented with pharmacological intervention.
Which foundations may like this?
We have developed an organoid model of diabetic neuropathy.
It has oligodendrocytes, myelin, and adding diabetic stimuli makes them lose myelination, and break down mitochondria.
Further yet, we show this can be prevented with pharmacological intervention.
Which foundations may like this?
a fluffy cat is sitting on a wooden table with the words `` help '' written on it .
ALT: a fluffy cat is sitting on a wooden table with the words `` help '' written on it .
media.tenor.com
November 13, 2025 at 5:22 PM
Help:
We have developed an organoid model of diabetic neuropathy.
It has oligodendrocytes, myelin, and adding diabetic stimuli makes them lose myelination, and break down mitochondria.
Further yet, we show this can be prevented with pharmacological intervention.
Which foundations may like this?
We have developed an organoid model of diabetic neuropathy.
It has oligodendrocytes, myelin, and adding diabetic stimuli makes them lose myelination, and break down mitochondria.
Further yet, we show this can be prevented with pharmacological intervention.
Which foundations may like this?
Reposted by Aleyah E. Goins
Brain-wide single-neuron bases of working memory for sounds in humans https://www.biorxiv.org/content/10.1101/2025.11.10.687666v1
November 11, 2025 at 10:15 AM
Brain-wide single-neuron bases of working memory for sounds in humans https://www.biorxiv.org/content/10.1101/2025.11.10.687666v1
unbelievable
The 59.2 kWh lithium-ion battery is mounted under the floor, between the chassis rails.
insideevs.com/news/778442/...
insideevs.com/news/778442/...
The New Toyota Hilux Is An EV
The trusty pickup will also gain a hydrogen fuel cell version, as Toyota pushes forward its “multi-pathway approach.”
insideevs.com
November 11, 2025 at 5:27 AM
unbelievable
Reposted by Aleyah E. Goins
People moan about AI taking people’s jobs, so interact and keep demand high for in person jobs
- Go to the post office when you need to renew/post/register things
- Go to the bank and get money out
- Go to the shops and spend money, stop buying online
- Go use public transport
- Go to the library
- Go to the post office when you need to renew/post/register things
- Go to the bank and get money out
- Go to the shops and spend money, stop buying online
- Go use public transport
- Go to the library
November 10, 2025 at 7:52 AM
People moan about AI taking people’s jobs, so interact and keep demand high for in person jobs
- Go to the post office when you need to renew/post/register things
- Go to the bank and get money out
- Go to the shops and spend money, stop buying online
- Go use public transport
- Go to the library
- Go to the post office when you need to renew/post/register things
- Go to the bank and get money out
- Go to the shops and spend money, stop buying online
- Go use public transport
- Go to the library
Very grateful to be at the right place and the right time to run alongside a champion.
#NYC #NYCMarathon #Legend #Kipchoge
#NYC #NYCMarathon #Legend #Kipchoge
November 11, 2025 at 4:36 AM
Very grateful to be at the right place and the right time to run alongside a champion.
#NYC #NYCMarathon #Legend #Kipchoge
#NYC #NYCMarathon #Legend #Kipchoge
Important announcement 📣 i’m serving face i’m sorry
November 11, 2025 at 4:32 AM
Important announcement 📣 i’m serving face i’m sorry
Reposted by Aleyah E. Goins
So true. But then MORE THINGS arrive to get done. And that's just rude.
IT HAPPENED TO ME: I stopped faffing about and Did The Thing and it turns out that this is What Gets Things Done.
November 10, 2025 at 8:42 PM
So true. But then MORE THINGS arrive to get done. And that's just rude.
November 11, 2025 at 4:01 AM
Reposted by Aleyah E. Goins
That’s exciting!
From an accidental discovery of hidden biology to a new framework to understanding and diagnosing rare disease. Thrilled to share the most recent work from our lab and the amazing Jimmy Ly.
wi.mit.edu/news/alterna...
wi.mit.edu/news/alterna...
Alternate proteins from the same gene contribute differently to health and rare disease | Whitehead Institute
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of rare disease, and present case studies of affected patients thro...
wi.mit.edu
November 8, 2025 at 1:35 PM
That’s exciting!
Reposted by Aleyah E. Goins
New human DRG atlas just dropped! 🌟
The BIG DRG paper is now up on @biorxiv-neursci.bsky.social www.biorxiv.org/content/10.1... so many people worked so hard to make this happen. Props to the whole PRECISION Human Pain Network.
A Reference Atlas of the Human Dorsal Root Ganglion
Somatosensory perception largely emerges from diverse peripheral sensory neurons whose cell bodies reside in dorsal root ganglia (DRG). Damage or dysfunction of DRG neurons is a major cause of chronic...
www.biorxiv.org
November 7, 2025 at 11:26 AM
New human DRG atlas just dropped! 🌟
Despite some controversy, a science giant has fallen to the very thing he showed a great mastery of; biology. #Biology #Neuroscience #genetics
James Watson, who co-discovered the structure of DNA, has died at age 97
James Watson, who co-discovered the structure of DNA has died at age 97. He was a scientific superstar until he made racist remarks that made him an outcast.
www.npr.org
November 8, 2025 at 2:28 AM
Despite some controversy, a science giant has fallen to the very thing he showed a great mastery of; biology. #Biology #Neuroscience #genetics
Reposted by Aleyah E. Goins
Excited to announce my thesis paper with is now in print at ELIfe! Excited to share our updated work on automating evoked touch/pain assays in rodents, and the further advancements we’ve made for #PainResearch!
elifesciences.org/reviewed-pre...
elifesciences.org/reviewed-pre...
October 30, 2025 at 3:19 PM
Excited to announce my thesis paper with is now in print at ELIfe! Excited to share our updated work on automating evoked touch/pain assays in rodents, and the further advancements we’ve made for #PainResearch!
elifesciences.org/reviewed-pre...
elifesciences.org/reviewed-pre...
When cancer invades nerves, inflammation pops off and causes pain! Ouch! 😬 Then, IL-6/IFNγ drives resistance to anti-PD-1 cancer treatment, lowers effectiveness 😱. The resistance was reversed by targeting nerve-injury signaling pathways. Critical discovery connecting #PainResearch to immunotherapy!
Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy - PubMed
Perineural invasion (PNI) is a well-established factor of poor prognosis in multiple cancer types<sup>1</sup>, yet its mechanism remains unclear. Here we provide clinical and mechanistic insights into...
pubmed.ncbi.nlm.nih.gov
October 8, 2025 at 5:10 PM
When cancer invades nerves, inflammation pops off and causes pain! Ouch! 😬 Then, IL-6/IFNγ drives resistance to anti-PD-1 cancer treatment, lowers effectiveness 😱. The resistance was reversed by targeting nerve-injury signaling pathways. Critical discovery connecting #PainResearch to immunotherapy!
Novel perineural invasion (PNI) mouse model mimics the intractable pain of head & neck cancer in humans 🤯, revealing that cancer-related nerve damage shares features with neurodegeneration. 🧠 Crucial tool for testing future pain treatments! 📈 #NYU #PainResearch #PNI #HNSCC
Perineural Invasion Exhibits Traits of Neurodegeneration - PubMed
Perineural invasion (PNI) frequently occurs in head and neck squamous cell carcinoma (HNSCC), which correlates with poor survival and induces intractable pain and numbness. There is no effective treat...
pubmed.ncbi.nlm.nih.gov
October 8, 2025 at 4:53 PM
Novel perineural invasion (PNI) mouse model mimics the intractable pain of head & neck cancer in humans 🤯, revealing that cancer-related nerve damage shares features with neurodegeneration. 🧠 Crucial tool for testing future pain treatments! 📈 #NYU #PainResearch #PNI #HNSCC
Reposted by Aleyah E. Goins
A blood test for pain?
New work in Nature identifies circulating biomarkers that distinguish chronic pain states—offering a path toward objective, biologically grounded diagnostics.
#PainResearch #Neuroskyence #Biomarkers #ScienceWatch #SciComm #ScienceInTranslation #ChronicPain
New work in Nature identifies circulating biomarkers that distinguish chronic pain states—offering a path toward objective, biologically grounded diagnostics.
#PainResearch #Neuroskyence #Biomarkers #ScienceWatch #SciComm #ScienceInTranslation #ChronicPain
Next-generation precision medicine for pain - Molecular Psychiatry
Molecular Psychiatry - Next-generation precision medicine for pain
www.nature.com
August 29, 2025 at 3:07 PM
A blood test for pain?
New work in Nature identifies circulating biomarkers that distinguish chronic pain states—offering a path toward objective, biologically grounded diagnostics.
#PainResearch #Neuroskyence #Biomarkers #ScienceWatch #SciComm #ScienceInTranslation #ChronicPain
New work in Nature identifies circulating biomarkers that distinguish chronic pain states—offering a path toward objective, biologically grounded diagnostics.
#PainResearch #Neuroskyence #Biomarkers #ScienceWatch #SciComm #ScienceInTranslation #ChronicPain
Reposted by Aleyah E. Goins
Incredible! A new imaging system has allowed researchers to map the entire adult mouse peripheral nervous system at micrometer resolution. This is a massive leap in understanding cellular interactions in health and disease. #Neuroscience www.sciencedirect.com/science/arti...
High-speed mapping of whole-mouse peripheral nerves at subcellular resolution
In contrast to the rapid advancements in mesoscale connectomic mapping of the mammalian brain, similar mapping of the peripheral nervous system has re…
www.sciencedirect.com
August 29, 2025 at 7:10 PM
Incredible! A new imaging system has allowed researchers to map the entire adult mouse peripheral nervous system at micrometer resolution. This is a massive leap in understanding cellular interactions in health and disease. #Neuroscience www.sciencedirect.com/science/arti...