Marek Glombik
@glombikm.bsky.social
postdoc in De Vega lab, Earlham Institute, Norwich, UK.
Pangenomes, polyploid crops, evolution and improvement.
Pangenomes, polyploid crops, evolution and improvement.
Reposted by Marek Glombik
A really nice article in The Scientist about q.e.d!
@qedscience.bsky.social - If you're not using it yet, now's the time!
www.the-scientist.com/q-e-d-an-ai-...
@qedscience.bsky.social - If you're not using it yet, now's the time!
www.the-scientist.com/q-e-d-an-ai-...
q.e.d: An AI Tool for Smarter Manuscript Review
A team of researchers developed q.e.d, an AI-powered system designed to deliver rigorous and constructive feedback on scientific manuscripts in minutes.
www.the-scientist.com
November 19, 2025 at 1:49 PM
A really nice article in The Scientist about q.e.d!
@qedscience.bsky.social - If you're not using it yet, now's the time!
www.the-scientist.com/q-e-d-an-ai-...
@qedscience.bsky.social - If you're not using it yet, now's the time!
www.the-scientist.com/q-e-d-an-ai-...
Reposted by Marek Glombik
Our latest paper has just been published in Cell!
doi.org/10.1016/j.ce...
We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.
doi.org/10.1016/j.ce...
We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.
November 5, 2025 at 5:20 PM
Our latest paper has just been published in Cell!
doi.org/10.1016/j.ce...
We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.
doi.org/10.1016/j.ce...
We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.
Reposted by Marek Glombik
I am looking for a PhD student to start in my lab at UCSB in Fall 2026, studying evolutionary biology. See attached flyer for more information. Please also share with potentially interested students. Thanks!
November 3, 2025 at 5:27 PM
I am looking for a PhD student to start in my lab at UCSB in Fall 2026, studying evolutionary biology. See attached flyer for more information. Please also share with potentially interested students. Thanks!
Reposted by Marek Glombik
I'm recruiting PhD students for the Barker Lab @uofa-eeb.bsky.social We study plant evolutionary genomics - polyploidy, hybridization & machine learning for genome evolution. Work with Selaginella, Xanthisma, Brassica & more. Funding available via CAMBIUM Fellowships. Reach out if interested! 🧬🌵🤖
October 24, 2025 at 5:01 AM
I'm recruiting PhD students for the Barker Lab @uofa-eeb.bsky.social We study plant evolutionary genomics - polyploidy, hybridization & machine learning for genome evolution. Work with Selaginella, Xanthisma, Brassica & more. Funding available via CAMBIUM Fellowships. Reach out if interested! 🧬🌵🤖
Reposted by Marek Glombik
Chromatin organization is measured in single cells using droplet microfluidics go.nature.com/3NCqwO1
rdcu.be/eNah5
rdcu.be/eNah5
Droplet Hi-C enables scalable, single-cell profiling of chromatin architecture in heterogeneous tissues - Nature Biotechnology
Chromatin organization is measured in single cells using droplet microfluidics.
go.nature.com
October 30, 2025 at 1:36 AM
Chromatin organization is measured in single cells using droplet microfluidics go.nature.com/3NCqwO1
rdcu.be/eNah5
rdcu.be/eNah5
Reposted by Marek Glombik
🚀 New preprint!
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
Natural variation in regulatory code revealed through Bayesian analysis of plant pan-genomes and pan-transcriptomes
Understanding the genetic code of cis-regulatory elements (CREs) is essential for engineering gene expression and modulating agronomic traits in crops. In plants, CREs underlying rapid evolution of ge...
biorxiv.org
October 29, 2025 at 4:47 PM
🚀 New preprint!
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
Reposted by Marek Glombik
Our new publication on HOBIT, a software tool for polyploid gene expression analysis. Compared with our previous method HomeoRoq (2014), HOBIT enables direct and higher-quality analysis of complex allohexaploid species such as bread wheat.
HOBIT: LRT to detect homeolog expression shifts in allopolyploids
Sun et al.
nph.onlinelibrary.wiley.com/doi/10.1111/...
Sun et al.
nph.onlinelibrary.wiley.com/doi/10.1111/...
October 28, 2025 at 7:32 PM
Our new publication on HOBIT, a software tool for polyploid gene expression analysis. Compared with our previous method HomeoRoq (2014), HOBIT enables direct and higher-quality analysis of complex allohexaploid species such as bread wheat.
Please spread the word to anyone who might be interested! #PhD available in our group
PHD: Looking for a computational #PhD with training in plant genomics, bioinformatics, and statistical modelling?
Apply for this fully-funded four year project at the Earlham Institute in collaboration with @ibers.bsky.social looking at genome regulation in Miscanthus hybrids.
Apply for this fully-funded four year project at the Earlham Institute in collaboration with @ibers.bsky.social looking at genome regulation in Miscanthus hybrids.
Understanding genome regulation in Miscanthus hybrids for sustainable bioenergy
4-year Norwich Research Park Biosciences Doctoral Training Partnership (NRPDTP) PhD
buff.ly
October 27, 2025 at 11:05 AM
Please spread the word to anyone who might be interested! #PhD available in our group
Reposted by Marek Glombik
Pre-phasing long reads improves structural variant genotyping. #LongReads #Sequencing #ReadsPhasing #StructuralVariants #Genotyping #Genomics #Bioinformatics
academic.oup.com/bioinformati...
academic.oup.com/bioinformati...
October 25, 2025 at 7:32 AM
Pre-phasing long reads improves structural variant genotyping. #LongReads #Sequencing #ReadsPhasing #StructuralVariants #Genotyping #Genomics #Bioinformatics
academic.oup.com/bioinformati...
academic.oup.com/bioinformati...
Reposted by Marek Glombik
Published today: One of the biggest #science #communication studies to date. We asked 71,922 people in 68 countries how they #engage with information about #science and combined the data with several country-level factors: journals.sagepub.com/doi/10.1177/... #OpenAccess
October 21, 2025 at 12:27 PM
Published today: One of the biggest #science #communication studies to date. We asked 71,922 people in 68 countries how they #engage with information about #science and combined the data with several country-level factors: journals.sagepub.com/doi/10.1177/... #OpenAccess
Reposted by Marek Glombik
Lunch today halfway around the world in Hangzhou and met a new asst professor who was very thankful for this resource. Please help out folks like them and other early career scientists with examples of job apps. Submit yours!
github.com/RILAB/statem...
github.com/RILAB/statem...
GitHub - RILAB/statements: Successful Job Applications and Grants
Successful Job Applications and Grants. Contribute to RILAB/statements development by creating an account on GitHub.
github.com
October 21, 2025 at 6:55 AM
Lunch today halfway around the world in Hangzhou and met a new asst professor who was very thankful for this resource. Please help out folks like them and other early career scientists with examples of job apps. Submit yours!
github.com/RILAB/statem...
github.com/RILAB/statem...
Reposted by Marek Glombik
Today we have published a new analysis of UK immigration costs, comparing the 2025 costs of skilled worker, researcher and student visas in the UK and 17 other leading science nations. This updates previous analysis from 2019, 2021 and 2024:
royalsociety.org/news-resourc...
royalsociety.org/news-resourc...
UK immigration costs: an international comparison of skilled worker, researcher and student visas in 2025 | Royal Society
2025 update to the Royal Society's analyses of upfront immigration costs in the UK and 17 other leading science nations.
royalsociety.org
October 21, 2025 at 9:23 AM
Today we have published a new analysis of UK immigration costs, comparing the 2025 costs of skilled worker, researcher and student visas in the UK and 17 other leading science nations. This updates previous analysis from 2019, 2021 and 2024:
royalsociety.org/news-resourc...
royalsociety.org/news-resourc...
Reposted by Marek Glombik
q.e.d Science
Critical Thinking AI for constructive criticism and science evaluation
qedscience.com
October 15, 2025 at 12:22 PM
Reposted by Marek Glombik
We extended the functionality of DMRcaller ( bioconductor.org/packages/DMR...) to incorporate ONT data directly from Dorado aligned bam files and maintain the information of the read the modification was detected on.
October 14, 2025 at 8:21 AM
We extended the functionality of DMRcaller ( bioconductor.org/packages/DMR...) to incorporate ONT data directly from Dorado aligned bam files and maintain the information of the read the modification was detected on.
Reposted by Marek Glombik
Apple is entering the protein folding arena.
SimpleFold: Folding Proteins is Simpler than You Think arxiv.org/abs/2509.18480 🧬🖥️🧪 github.com/apple/ml-sim...
SimpleFold: Folding Proteins is Simpler than You Think arxiv.org/abs/2509.18480 🧬🖥️🧪 github.com/apple/ml-sim...
September 25, 2025 at 9:02 AM
Apple is entering the protein folding arena.
SimpleFold: Folding Proteins is Simpler than You Think arxiv.org/abs/2509.18480 🧬🖥️🧪 github.com/apple/ml-sim...
SimpleFold: Folding Proteins is Simpler than You Think arxiv.org/abs/2509.18480 🧬🖥️🧪 github.com/apple/ml-sim...
Reposted by Marek Glombik
I get that the news cycle is packed right now, but I just heard from a colleague at the Smithsonian that this is fully a GIANT SQUID BEING EATEN BY A SPERM WHALE and it’s possibly the first ever confirmed video according to a friend at NOAA
10 YEAR OLD ME IS LOSING HER MIND (a thread 🧵)
10 YEAR OLD ME IS LOSING HER MIND (a thread 🧵)
September 24, 2025 at 8:30 PM
I get that the news cycle is packed right now, but I just heard from a colleague at the Smithsonian that this is fully a GIANT SQUID BEING EATEN BY A SPERM WHALE and it’s possibly the first ever confirmed video according to a friend at NOAA
10 YEAR OLD ME IS LOSING HER MIND (a thread 🧵)
10 YEAR OLD ME IS LOSING HER MIND (a thread 🧵)
Reposted by Marek Glombik
Later TODAY at 15:00 CEST! Efficient evidence-based genome annotation with EviAnn 🧬
👉 www.erga-biodiversity.eu/post/efficie... #genomeannotation #genomes #seminar #research #EviAnn @ebpgenome.bsky.social
👉 www.erga-biodiversity.eu/post/efficie... #genomeannotation #genomes #seminar #research #EviAnn @ebpgenome.bsky.social
September 23, 2025 at 7:17 AM
Later TODAY at 15:00 CEST! Efficient evidence-based genome annotation with EviAnn 🧬
👉 www.erga-biodiversity.eu/post/efficie... #genomeannotation #genomes #seminar #research #EviAnn @ebpgenome.bsky.social
👉 www.erga-biodiversity.eu/post/efficie... #genomeannotation #genomes #seminar #research #EviAnn @ebpgenome.bsky.social
Reposted by Marek Glombik
Reposted by Marek Glombik
I am editing a collection on "plant epigenetic regulation" for BMC Plant Biology. If you think that your paper might fit there please contact me or send it through the submission system to our collection: www.biomedcentral.com/collections/...
Call for papers - Plant epigenetic regulation
www.biomedcentral.com
September 16, 2025 at 1:24 PM
I am editing a collection on "plant epigenetic regulation" for BMC Plant Biology. If you think that your paper might fit there please contact me or send it through the submission system to our collection: www.biomedcentral.com/collections/...
Reposted by Marek Glombik
🌎👩🔬 For 15+ years biology has accumulated petabytes (million gigabytes) of🧬DNA sequencing data🧬 from the far reaches of our planet.🦠🍄🌵
Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open.
doi.org/10.1101/2024...
Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open.
doi.org/10.1101/2024...
September 3, 2025 at 8:39 AM
🌎👩🔬 For 15+ years biology has accumulated petabytes (million gigabytes) of🧬DNA sequencing data🧬 from the far reaches of our planet.🦠🍄🌵
Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open.
doi.org/10.1101/2024...
Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open.
doi.org/10.1101/2024...
Reposted by Marek Glombik
I'm looking to recruit a PhD student to study patterns of local adaptation and introgression across the spruce hybrid zone in the Rockies near Calgary. Projects can include field work, bioinformatics, pop gen theory, or comparison to plant/ conifer species
yeamanlab.weebly.com/uploads/5/7/...
yeamanlab.weebly.com/uploads/5/7/...
August 20, 2025 at 8:19 PM
I'm looking to recruit a PhD student to study patterns of local adaptation and introgression across the spruce hybrid zone in the Rockies near Calgary. Projects can include field work, bioinformatics, pop gen theory, or comparison to plant/ conifer species
yeamanlab.weebly.com/uploads/5/7/...
yeamanlab.weebly.com/uploads/5/7/...
Reposted by Marek Glombik
Postdoc opportunity with @tomasbruna.bsky.social here at @jgi.doe.gov @berkeleylab.lbl.gov:
Develop, benchmark, and apply Plant Genomic Language Models (gLMs) 🌿🧬💻
jobs.lbl.gov/jobs/computa...
#AI #PlantGenomics #gLMs #Postdoc
Develop, benchmark, and apply Plant Genomic Language Models (gLMs) 🌿🧬💻
jobs.lbl.gov/jobs/computa...
#AI #PlantGenomics #gLMs #Postdoc
August 21, 2025 at 12:05 AM
Postdoc opportunity with @tomasbruna.bsky.social here at @jgi.doe.gov @berkeleylab.lbl.gov:
Develop, benchmark, and apply Plant Genomic Language Models (gLMs) 🌿🧬💻
jobs.lbl.gov/jobs/computa...
#AI #PlantGenomics #gLMs #Postdoc
Develop, benchmark, and apply Plant Genomic Language Models (gLMs) 🌿🧬💻
jobs.lbl.gov/jobs/computa...
#AI #PlantGenomics #gLMs #Postdoc
Reposted by Marek Glombik
Happy to be able to finally share our NLR pangenome paper, out now in CHM.
"Pangenomic context reveals the extent of intraspecific plant NLR evolution"
www.cell.com/cell-host-mi...
#plantscience #plantimmunity #pangenomes #science #nlr
"Pangenomic context reveals the extent of intraspecific plant NLR evolution"
www.cell.com/cell-host-mi...
#plantscience #plantimmunity #pangenomes #science #nlr
Pangenomic context reveals the extent of intraspecific plant NLR evolution
Individual- and population-level diversity is required for pathogen defense by nucleotide-binding
site leucine-rich repeat (NLR) proteins. Teasdale et al. leverage annotated, divergent
A. thaliana gen...
www.cell.com
August 14, 2025 at 5:55 AM
Happy to be able to finally share our NLR pangenome paper, out now in CHM.
"Pangenomic context reveals the extent of intraspecific plant NLR evolution"
www.cell.com/cell-host-mi...
#plantscience #plantimmunity #pangenomes #science #nlr
"Pangenomic context reveals the extent of intraspecific plant NLR evolution"
www.cell.com/cell-host-mi...
#plantscience #plantimmunity #pangenomes #science #nlr
Reposted by Marek Glombik
Prompt-based bioinformatics: a new interface for multi-omics analysis www.nature.com/articles/s41... read free: rdcu.be/eAnf4
Vibeoinformatics... computational vibeology... 🧬🖥️🧪
Vibeoinformatics... computational vibeology... 🧬🖥️🧪
Prompt-based bioinformatics: a new interface for multi-omics analysis - Nature Reviews Genetics
Prompt-based methods, which involve the careful design of inputs to guide large language model (LLM) outputs, are beginning to reshape bioinformatic analytical workflows. The authors compare prompt-dr...
www.nature.com
August 14, 2025 at 11:51 AM
Prompt-based bioinformatics: a new interface for multi-omics analysis www.nature.com/articles/s41... read free: rdcu.be/eAnf4
Vibeoinformatics... computational vibeology... 🧬🖥️🧪
Vibeoinformatics... computational vibeology... 🧬🖥️🧪
Reposted by Marek Glombik
Oxford Nanopore @nanoporetech.com CEO will leave the company in 2026 after 20 years in the role.
August 11, 2025 at 8:48 AM
Oxford Nanopore @nanoporetech.com CEO will leave the company in 2026 after 20 years in the role.