Nature - Experiments with human volunteers and macaques show that expectations produced by probabilistic cueing of future sensory inputs shape motor circuit dynamics in order to increase the...

Communications Medicine - Meine, McPherson et al. assess risk and resilience factors in Swiss medical interns predicting skills improvement, burnout, wellbeing and career motivation. Based on...

Data passively obtained from smartphones and wearables can provide nearly continuous objective information that enables quantification of states and traits across broad physiological, behavioral, and ...

An expert recommendation is presented for the design and evaluation of research studies using transcranial electrical stimulation, resulting in the selection of a 66-point checklist aimed at improving the quality of transcranial electrical stimulation studies.

Scientific Reports - Leveling up fun: learning progress, expectations, and success influence enjoyment in video games

A core strength of computational psychiatry is its focus on theory-driven research, in which cognitive processes are precisely quantified using computational models that formalize specific theoretical mechanisms. However, the data used in these studies often come from traditional laboratory-based cognitive tasks, which have unclear ecological validity. In this review we propose that the same theoretical frameworks and computational models can be applied to real-world data such as experience sampling, passive data, and digital-behavior data (e.g., online activity such as on social media). In turn, modeling real-world data can benefit from a theory-driven computational approach to move from purely predictive to explanatory power. We illustrate these points using emerging studies and discuss the challenges and opportunities of using real-world data in computational psychiatry.

Interactions between metabolic interoception and regulation may drive comorbidity between mental and metabolic ill-health.

Reframing of arousal as a latent dynamical system can reconstruct multidimensional measurements of large-scale spatiotemporal brain dynamics on the timescale of seconds in mice.

The relationship between subjective (self-reported) and objective (performance-based) cognitive functioning has significant clinical implications acro…

“Am I hungry? Did I overeat at lunch?” Gastric interoception - the sensing, interpretation, and regulation of signals from the gastrointestinal system…

Background: Ecological momentary assessment (EMA) is increasingly being incorporated into intervention studies to acquire a more fine-grained and ecologically valid assessment of change. The added uti...

Mental health symptoms, like those in obsessive-compulsive disorder (OCD), show pronounced fluctuations over time. However, little is known about the underlying factors driving these fluctuations. Whi...

Interoception-the sensing and perception of the internal viscera-is widely cast as a transdiagnostic mechanism linking brain-body interaction to mental illness. Prevailing models propose that altered ...

ALT: a penguin is sticking his head out of a hole next to a job application