glabrahams.bsky.social
@glabrahams.bsky.social
Reposted
I'd love to say lots of nice things about this invaluable preventable disease tracker from @monscience.bsky.social and team at Think Global Health. It's an incredible resource.

But I can't get over my anger & sadness that this resource is even needed.
www.thinkglobalhealth.org/article/vacc...
Vaccine-Preventable Disease: A Global Tracker | Think Global Health
This map is updated weekly and visualizes outbreaks of nine childhood diseases in collaboration with the International Society for Infectious Diseases
www.thinkglobalhealth.org
October 29, 2025 at 12:35 PM
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In Feb 2025, Louisiana Surgeon General Ralph Abraham ordered the state health department to stop promoting vaccines.

Now, the news comes out that the health department failed to inform the public or even healthcare professionals about the largest whooping cough outbreak in more than a decade.
Louisiana officials waited months to warn public of whooping cough outbreak
After a whooping cough outbreak killed two infants, Louisiana health officials waited months to officially alert physicians or do public outreach. That's not the typical public health response.
www.npr.org
October 30, 2025 at 2:25 AM
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A new Nature Medicine study analyzing health records from >100 million people in the US offers compelling evidence that reactivation of varicella-zoster virus (VZV) ,the same virus that causes chickenpox and shingles may contribute to dementia risk.
www.nature.com/articles/s41...
Varicella-zoster virus reactivation and the risk of dementia - Nature Medicine
Large-scale longitudinal health records reveal consistent association of varicella-zoster virus reactivation with dementia.
www.nature.com
October 6, 2025 at 4:46 PM
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The virus hijacks the host ribosome by installing a translation initiation complex with preference for viral mRNA
October 6, 2025 at 9:34 PM
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Important piece from Sarah Stanley at Berkeley on new NIH definitions that can be construed to arbitrarily halt research that is both safe and important to public health and future cures www.statnews.com/2025/10/06/g... via @statnews.com
The NIH ordered me to stop my ‘dangerous’ gain-of-function research. It isn’t dangerous at all
Safe gain-of-function research is necessary to identify new treatments for diseases like for tuberculosis — but the NIH has imposed unfounded stops.
www.statnews.com
October 6, 2025 at 12:15 PM
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This is quite cool!

"the AveloMask Kit, a user-friendly, non-invasive face mask that captures exhaled aerosols and transfers them into a buffer tube for molecular detection of respiratory tract infections"
#IDSky #ClinMicro #TBSky
journals.asm.org/doi/10.1128/...
AveloMask, a novel breath aerosol collection kit for airborne Mycobacterium tuberculosis: a proof-of-principle assessment | Journal of Clinical Microbiology
Tuberculosis (TB) remains the world’s deadliest infectious disease, yet diagnosis still relies heavily on sputum, which many patients struggle to produce. This study introduces the AveloMask Kit, a…
journals.asm.org
September 13, 2025 at 3:10 PM
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Connecticut, Maine,
Massachusetts, New Jersey, New York State, Pennsylvania, Rhode Island and New York City formed the Northeast Public Health Collaborative.

They’ll issue their own vaccine recommendations & coordinate public health efforts.

Photo: @luckytran.com

🧪 www.nyc.gov/site/doh/abo...
September 18, 2025 at 6:47 PM
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@era4tb.bsky.social researchers found compounds that block TB’s ESX-1 system (used to damage immune cells) while also improving effectiveness of ethionamide. A dual-action step against drug-resistant TB.

👉 𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: bit.ly/3VJJJBw
September 11, 2025 at 8:17 AM
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#Tuberculosis severity varies widely between people; why is this? This study uses the #CollaborativeCross mouse panel to identify the protease #cathepsin Z (CTSZ) as a conserved regulator of #TB outcomes via its influence on CXCL1 in mice & in humans @plosbiology.org 🧪 plos.io/4phwRA8
September 11, 2025 at 8:23 AM
Selection at the GSDMC locus in horses and its implications for human mobility | Science www.science.org/doi/10.1126/...
Selection at the GSDMC locus in horses and its implications for human mobility
Horsepower revolutionized human history through enhanced mobility, transport, and warfare. However, the suite of biological traits that reshaped horses during domestication remains unclear. We scanned...
www.science.org
September 1, 2025 at 9:12 PM
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Melanocyte-dependent macrophage redistribution enhances skin immunity upon acute stress | PNAS www.pnas.org/doi/10.1073/... 🧪
Melanocyte-dependent macrophage redistribution enhances skin immunity upon acute stress | PNAS
It is well established that stress generally suppresses immunity. However, under certain conditions, acute stress has been shown to stimulate the i...
www.pnas.org
August 26, 2025 at 5:46 PM
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Good news for a change!

🎉 A new clinical trial in South Africa appears to have cured* a young woman of HIV. 🎉

10 people have been cured before, but this time is different 👇

*(Cure= in remission for 2+ years w/o treatment)
Whatever happened to ... the race to cure HIV? There's promising news
At the International AIDS Society meeting this year, a young woman from South Africa spoke. She is the first Black woman from Africa to be potentially cured of HIV.
www.npr.org
August 26, 2025 at 4:03 PM
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A fun 15 minute talk by evolutionary anthropologist David Samson putting human sleep in context with that of other great apes, primates, and other species 🧪 #BioAnth www.youtube.com/watch?v=joHF...
The Mystery of Primate Sleep
YouTube video by David R. Samson
www.youtube.com
August 26, 2025 at 7:45 PM
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Wind turbines kill a massive number of bats. These animals seem to be unusually attracted to turbines, and researchers have long puzzled over why. 🦇🧪

For @science.org, I wrote about a new study that suggests they might be responding to a visual cue. www.science.org/content/arti...
Bats may mistake wind turbines for open sky, causing deadly collisions
Study may help explain why giant blades kill millions of the animals every year
https://www.science.org/content/article/bats-may-mistake-wind-turbines-open-sky-causing-deadly-collisions🧪
August 26, 2025 at 8:43 PM
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Our #CryoET story on how a top antimalarial drug candidate perturbs the native malarial translation machinery is out @natsmb.nature.com🥳 rdcu.be/eBbrH

A massive team effort led by @leonieanton.bsky.social Meseret Haile & Wenjing Cheng in collaboration with Jerzy Dziekan & the Alan Cowman! #TeamTomo
Integrated structural biology of the native malarial translation machinery and its inhibition by an antimalarial drug
Nature Structural & Molecular Biology - Integrated structural biology approach leveraging in situ cryo-electron tomography reveals molecular details of the native malarial translation...
rdcu.be
August 18, 2025 at 12:13 PM
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1/ Excited to share the first preprint from my lab! 🎉

My postdoc Paz asked how cholera toxin (CT) helps Vibrio cholerae thrive in the gut.

Turns out, CT rewires epithelial metabolism toward L-lactate production—fueling pathogen growth in the small intestine during disease
Cholera toxin-induced disease generates epithelial cell-derived L-lactate that promotes Vibrio cholerae growth in the small intestine
Cholera toxin (CT) promotes Vibrio cholerae colonization by altering gut metabolism to favor pathogen growth. We have previously found that CT-induced disease leads to increased concentrations of L-la...
www.biorxiv.org
August 18, 2025 at 9:13 PM
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I spoke about my forthcoming book with @peterhotezmdphd.bsky.social, #ScienceUnderSiege, in the Islesboro Forum, Islesboro Maine, August 10:
www.youtube.com/watch?v=s9uu...
The Islesboro Forum 8/10/25 August 10 @ 5:30 pm - 6:30 pmDr. Michael E. Mann "Science Under Siege"
YouTube video by Glotzl Creative Imaging
www.youtube.com
August 17, 2025 at 6:29 PM
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How AI Can Enhance Early Detection of Emerging #Viruses: @unlv.edu study

Coupling #wastewater #surveillance and a newly developed AI algorithm can help public health organizations more quickly predict potential outbreaks

www.unlv.edu/news/article...
How AI Can Enhance Early Detection of Emerging Viruses: UNLV Study
Coupling wastewater surveillance and a newly developed AI algorithm can help public health organizations more quickly predict potential outbreaks.
www.unlv.edu
August 18, 2025 at 3:36 PM
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#NewResearch

Prion-like proteins in Escherichia coli trigger an abortive infection mechanism in response to phage infection—a process similar to amyloid-mediated immune signalling in fungi and animals.

#MicroSky 🦠

www.nature.com/articles/s41...
Characterization of an amyloid-based antiphage defence system in Escherichia coli - Nature Microbiology
Prion-like proteins in Escherichia coli trigger an abortive infection mechanism in response to phage infection—a process similar to amyloid-mediated immune signalling in fungi and animals.
www.nature.com
August 15, 2025 at 2:53 PM
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Read the associated news and views:

Microbial chocolatiers of fine flavour 🍫

by Pablo Cruz-Morales

www.nature.com/articles/s41...
August 18, 2025 at 3:37 PM
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Sign the letter from the Canadian Aerosol Transmission Coalition: We support the latest draft CSA Z94.4, Selection, Use and Care of Respirators – to protect ALL workers, especially healthcare.

www.aerosoltransmissioncoalition.ca
aerosoltransmissioncoalition.ca
The home page of the Canadian Aerosol Transmission Coalition – a group of individuals sharing their knowledge and expertise to help guide government leaders and public health officials with their deci...
www.aerosoltransmissioncoalition.ca
August 17, 2025 at 6:59 AM