Gary Patti
@gjpattij.bsky.social
metabophile (muh-tab-uh-fil'): a person obsessed with all things metabolism, metabolomics
Reposted by Gary Patti
“The prohibited activities would include joint research, co-authorship on papers, and advising a foreign graduate student or postdoctoral fellow. The language is retroactive, meaning any interactions during the previous 5 years could make a scientist ineligible for future federal funding.”
U.S. Congress considers sweeping ban on Chinese collaborations
Researchers speak out against proposal that would bar funding for U.S. scientists working with Chinese partners or training Chinese students
www.science.org
November 14, 2025 at 1:03 AM
“The prohibited activities would include joint research, co-authorship on papers, and advising a foreign graduate student or postdoctoral fellow. The language is retroactive, meaning any interactions during the previous 5 years could make a scientist ineligible for future federal funding.”
Reposted by Gary Patti
Gut microbiota protect against hepatic steatosis by degrading sorbitol derived from dietary glucose @gjpattij.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
October 30, 2025 at 12:00 AM
Gut microbiota protect against hepatic steatosis by degrading sorbitol derived from dietary glucose @gjpattij.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Gary Patti
6/ So what can you do?
✔️ Choose supplements that are third-party tested for heavy metals (USP, NSF, or Informed Sport).
✔️ Prioritize whole-food protein sources when possible.
✔️ Advocate for stronger supplement regulation as the industry has little oversight.
✔️ Choose supplements that are third-party tested for heavy metals (USP, NSF, or Informed Sport).
✔️ Prioritize whole-food protein sources when possible.
✔️ Advocate for stronger supplement regulation as the industry has little oversight.
October 21, 2025 at 6:20 PM
6/ So what can you do?
✔️ Choose supplements that are third-party tested for heavy metals (USP, NSF, or Informed Sport).
✔️ Prioritize whole-food protein sources when possible.
✔️ Advocate for stronger supplement regulation as the industry has little oversight.
✔️ Choose supplements that are third-party tested for heavy metals (USP, NSF, or Informed Sport).
✔️ Prioritize whole-food protein sources when possible.
✔️ Advocate for stronger supplement regulation as the industry has little oversight.
Reposted by Gary Patti
Excited to share our work on discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine biosynthesis. @cp-cellmetabolism.bsky.social www.cell.com/cell-metabol...
Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis
Khan et al. apply machine learning to identify substrates of UNC93A, SLC45A4, and
SLC25A45. Biochemical assays and in vivo metabolite tracing establish SLC25A45 as
a key mediator of mitochondrial impo...
www.cell.com
October 11, 2025 at 4:15 PM
Excited to share our work on discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine biosynthesis. @cp-cellmetabolism.bsky.social www.cell.com/cell-metabol...
Reposted by Gary Patti
1/ RFK Jr.’s promised autism “report” landed this week. Instead of new science, we got headlines, a press conference, and far-reaching claims drawn from decades of existing research. Parents and pregnant people were left with overwhelming anxiety. Here’s what the evidence actually says 👇
September 25, 2025 at 2:22 PM
1/ RFK Jr.’s promised autism “report” landed this week. Instead of new science, we got headlines, a press conference, and far-reaching claims drawn from decades of existing research. Parents and pregnant people were left with overwhelming anxiety. Here’s what the evidence actually says 👇
The Washington Post did a great job of summarizing a complex topic. There is still so much to learn about the connections between the exposome and cancer. Thanks for including me.
Gift link!
Toxins, Tech and Tumors: Is Modern Life Fueling the Rise of Cancer in Millennials?
By Ariana Eunjung Cha, Álvaro Valiño and Dan Keating
@arianaec.bsky.social @alvarovalino.bsky.social and @dtkeating.bsky.social
Toxins, Tech and Tumors: Is Modern Life Fueling the Rise of Cancer in Millennials?
By Ariana Eunjung Cha, Álvaro Valiño and Dan Keating
@arianaec.bsky.social @alvarovalino.bsky.social and @dtkeating.bsky.social
What researchers suspect may be fueling cancer among millennials
Studies suggest modern life may be fueling the rise of cancer in younger adults, with factors like ultra-processed foods and chemicals under scrutiny.
wapo.st
September 24, 2025 at 11:12 PM
The Washington Post did a great job of summarizing a complex topic. There is still so much to learn about the connections between the exposome and cancer. Thanks for including me.
Reposted by Gary Patti
Research in Scientific Reports suggests that blue-throated macaws can learn new actions by watching other macaws interact. The study indicates that this approach to learning is not exclusive to humans. go.nature.com/4g8p43m 🧪
September 14, 2025 at 1:15 AM
Research in Scientific Reports suggests that blue-throated macaws can learn new actions by watching other macaws interact. The study indicates that this approach to learning is not exclusive to humans. go.nature.com/4g8p43m 🧪
Reposted by Gary Patti
defunding children's brain cancer research. @endpts.com
August 25, 2025 at 11:43 PM
defunding children's brain cancer research. @endpts.com
Reposted by Gary Patti
I have a first serious attempt to estimate the consequences of multi-year funding for July.
For new R01s, the amount of additional expenditure was
$135 M
The number of additional R01s that could have been funded is
182
1/9
For new R01s, the amount of additional expenditure was
$135 M
The number of additional R01s that could have been funded is
182
1/9
a man in a shirt and tie is touching his forehead
ALT: a man in a shirt and tie is touching his forehead
media.tenor.com
August 14, 2025 at 8:54 PM
I have a first serious attempt to estimate the consequences of multi-year funding for July.
For new R01s, the amount of additional expenditure was
$135 M
The number of additional R01s that could have been funded is
182
1/9
For new R01s, the amount of additional expenditure was
$135 M
The number of additional R01s that could have been funded is
182
1/9
Reposted by Gary Patti
Here are some of the highlights of the appropriations bill that the Senate appropriations committee just approved:
$48.7 billion for NIH, an increase of $400 million
Rejects the proposal to cap
indirect cost rates at 15%
Includes a provision to prevent MYF that would reduce the number of grants
$48.7 billion for NIH, an increase of $400 million
Rejects the proposal to cap
indirect cost rates at 15%
Includes a provision to prevent MYF that would reduce the number of grants
www.appropriations.senate.gov
July 31, 2025 at 7:31 PM
Here are some of the highlights of the appropriations bill that the Senate appropriations committee just approved:
$48.7 billion for NIH, an increase of $400 million
Rejects the proposal to cap
indirect cost rates at 15%
Includes a provision to prevent MYF that would reduce the number of grants
$48.7 billion for NIH, an increase of $400 million
Rejects the proposal to cap
indirect cost rates at 15%
Includes a provision to prevent MYF that would reduce the number of grants
Reposted by Gary Patti
Even with flat funding for the NIH, under the current FY26 plan, there will be 60% less cancer research and much less research funded overall. We need to make sure Congress understands these tricks and protects against them in their budget plan.
Odds of winning NIH grants plummet as new funding policy and spending delays bite
Funding multiyear grants up front will sharply cut number of investigators receiving awards
www.science.org
July 29, 2025 at 11:30 AM
Even with flat funding for the NIH, under the current FY26 plan, there will be 60% less cancer research and much less research funded overall. We need to make sure Congress understands these tricks and protects against them in their budget plan.
Reposted by Gary Patti
1/ Since January, over 5,500 NIH-funded projects have been paused. That includes cancer trials, Alzheimer’s research, maternal health studies. This is work that directly impacts our lives.
And people aren't talking about it enough.
Let’s fix that 🧵
And people aren't talking about it enough.
Let’s fix that 🧵
July 23, 2025 at 9:24 PM
1/ Since January, over 5,500 NIH-funded projects have been paused. That includes cancer trials, Alzheimer’s research, maternal health studies. This is work that directly impacts our lives.
And people aren't talking about it enough.
Let’s fix that 🧵
And people aren't talking about it enough.
Let’s fix that 🧵
Reposted by Gary Patti
RIP Alan Marshall, one of the greatest mass spectrometrists ever, and a great human to boot.
nationalmaglab.org/careers/meet...
nationalmaglab.org/careers/meet...
Alan Marshall: A scientist and a Gentleman - MagLab
Meet one of the greatest innovators in the history of mass spectrometry, hard at work.
nationalmaglab.org
June 12, 2025 at 2:03 PM
RIP Alan Marshall, one of the greatest mass spectrometrists ever, and a great human to boot.
nationalmaglab.org/careers/meet...
nationalmaglab.org/careers/meet...
Reposted by Gary Patti
Join @drwendieberg.bsky.social for this half hour of discussion of supplemental breast cancer screening for women with dense breast tissue.
Join me on Sirius XM Doctor Radio (Channel 110) Monday 6/2/25 at 1:00-1:30 pm ET with Dr. Miriam Greene @nyulangone.bsky.social discussing @densebreastinfo.bsky.social and supplemental screening for women with dense breasts. Thank you @bcrfcure.bsky.social for supporting our research on CEM.
June 1, 2025 at 9:29 PM
Join @drwendieberg.bsky.social for this half hour of discussion of supplemental breast cancer screening for women with dense breast tissue.
Reposted by Gary Patti
"Gold standard science"
May 31, 2025 at 3:00 PM
"Gold standard science"
Reposted by Gary Patti
![[Person with ponytail wearing lab coat hands balloon to another person in front of a springboard, a magnet hanging from above, and then a target] PERSON WITH PONYTAIL to Person 2: Rub this balloon against your head, then go jump past that magnet toward the target on the wall. [caption] Before the bathroom scale was invented, the only way to weigh people was mass spectrometry.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cz73r7iyiqn26upot4jtjdhk/bafkreid7lnvd7afmasx3nxi6anxmyhbatpaw54za3kiw3eaoclrf722faq@jpeg)
Reposted by Gary Patti
May 25, 2025 at 3:27 PM
Reposted by Gary Patti
"Protein may be hot, but it’s fiber that Americans need to eat a lot more of."
"To get the full health benefits of fiber, it’s important to eat a variety of naturally fiber-rich foods and not rely on supplements...could actually lead to health problems..."
gift link www.wsj.com/health/welln...
"To get the full health benefits of fiber, it’s important to eat a variety of naturally fiber-rich foods and not rely on supplements...could actually lead to health problems..."
gift link www.wsj.com/health/welln...
Americans Don’t Eat Enough Fiber. Here’s Why That Worries Nutrition Experts
The latest science suggests our fiber-poor diets trigger inflammation and contribute to a range of related diseases.
www.wsj.com
May 25, 2025 at 4:05 PM
"Protein may be hot, but it’s fiber that Americans need to eat a lot more of."
"To get the full health benefits of fiber, it’s important to eat a variety of naturally fiber-rich foods and not rely on supplements...could actually lead to health problems..."
gift link www.wsj.com/health/welln...
"To get the full health benefits of fiber, it’s important to eat a variety of naturally fiber-rich foods and not rely on supplements...could actually lead to health problems..."
gift link www.wsj.com/health/welln...
Reposted by Gary Patti
Senate Democrats Host Forum on HHS: Day 2
YouTube video by Senator Peter Welch
www.youtube.com
May 22, 2025 at 9:52 AM
Reposted by Gary Patti
Another good use of 5 minutes of your time.
Academic workers across the country are calling 📞 Legislators to ask them to sign on to bipartisan letters ✉️ in support of robust NIH funding and opposing the 15% indirect cost caps. Take 5 minutes to call your legislators today. Deadline is May 19th.
docs.google.com/document/d/1...
docs.google.com/document/d/1...
May 15, 2025 at 6:27 PM
Another good use of 5 minutes of your time.
Reposted by Gary Patti
I have previously posted about the slow issuance of NIH award in fiscal year 2025 compared to fiscal year 2024.
jeremymberg.github.io/jeremyberg.g...
These data were across all of the institutes and centers at NIH.
The results can be examined for each institute and center.
1/n
jeremymberg.github.io/jeremyberg.g...
These data were across all of the institutes and centers at NIH.
The results can be examined for each institute and center.
1/n
NIH_since_1_20_25
jeremymberg.github.io
May 7, 2025 at 11:59 AM
I have previously posted about the slow issuance of NIH award in fiscal year 2025 compared to fiscal year 2024.
jeremymberg.github.io/jeremyberg.g...
These data were across all of the institutes and centers at NIH.
The results can be examined for each institute and center.
1/n
jeremymberg.github.io/jeremyberg.g...
These data were across all of the institutes and centers at NIH.
The results can be examined for each institute and center.
1/n
Reposted by Gary Patti
The Sable Award lecture at METPHYS2025 was really remarkable!
Tremendous congratulations to this years exceptional member of our community Kivanc Birsoy
Tremendous congratulations to this years exceptional member of our community Kivanc Birsoy
May 1, 2025 at 10:04 PM
The Sable Award lecture at METPHYS2025 was really remarkable!
Tremendous congratulations to this years exceptional member of our community Kivanc Birsoy
Tremendous congratulations to this years exceptional member of our community Kivanc Birsoy
Reposted by Gary Patti
Deaths from heart disease down 75%, that’s NIH.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
April 28, 2025 at 5:20 PM
Deaths from heart disease down 75%, that’s NIH.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
Reposted by Gary Patti
A beautiful day in Princeton @princeton.bsky.social to host our Ludwig Distinguished speaker Dr Kivanc Birsoy from Rockefeller @ludwigcancer.bsky.social
April 24, 2025 at 1:41 PM
A beautiful day in Princeton @princeton.bsky.social to host our Ludwig Distinguished speaker Dr Kivanc Birsoy from Rockefeller @ludwigcancer.bsky.social