Giovanni D’Angelo
@giodang.bsky.social
Lipid cell biologist @EPFL
Reposted by Giovanni D’Angelo
#CellBio community, this one is for you! Applications are open for the #LakeConference on Modeling Life from Cells to Tissues – co-hosted with Circuit Neuroscience Basel!
📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.
Apply to attend by 12/12: alleninstitute.org/events/aics-...
📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.
Apply to attend by 12/12: alleninstitute.org/events/aics-...
2026 Lake Conference: Modeling Life from Cells to Tissues
Join the Allen Institute for Cell Science and Circuit Neuroscience Basel in Seattle, Washington, April 20–22, 2026, for a 3 day conference, Modeling...
alleninstitute.org
October 20, 2025 at 9:33 PM
#CellBio community, this one is for you! Applications are open for the #LakeConference on Modeling Life from Cells to Tissues – co-hosted with Circuit Neuroscience Basel!
📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.
Apply to attend by 12/12: alleninstitute.org/events/aics-...
📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.
Apply to attend by 12/12: alleninstitute.org/events/aics-...
Very interesting paper… congratulations
Proud to share a preprint of our paper on how bridge-like lipid transport protein VPS13C senses lysosomal membrane tension in anticipation of membrane lesions to initiate net ER-to-lysosome lipid transfer for efficient lysosomal repair www.biorxiv.org/content/10.1...
VPS13C/PARK23 initiates lipid transfer and membrane remodeling for efficient lysosomal repair
Perturbations in lysosome integrity are tightly linked to neurological disorders and ageing, but the underlying pathogenic mechanisms are incompletely understood. Using an unbiased proteomic approach,...
www.biorxiv.org
October 25, 2025 at 3:13 PM
Very interesting paper… congratulations
Reposted by Giovanni D’Angelo
Proud to share a preprint of our paper on how bridge-like lipid transport protein VPS13C senses lysosomal membrane tension in anticipation of membrane lesions to initiate net ER-to-lysosome lipid transfer for efficient lysosomal repair www.biorxiv.org/content/10.1...
VPS13C/PARK23 initiates lipid transfer and membrane remodeling for efficient lysosomal repair
Perturbations in lysosome integrity are tightly linked to neurological disorders and ageing, but the underlying pathogenic mechanisms are incompletely understood. Using an unbiased proteomic approach,...
www.biorxiv.org
October 25, 2025 at 1:11 PM
Proud to share a preprint of our paper on how bridge-like lipid transport protein VPS13C senses lysosomal membrane tension in anticipation of membrane lesions to initiate net ER-to-lysosome lipid transfer for efficient lysosomal repair www.biorxiv.org/content/10.1...
Reposted by Giovanni D’Angelo
Lipid imaging on the cover of @nature.com! Great times for lipid cell biology indeed. And a fantastic recognition of all the hard work by the team, especially Juan M. Iglesias-Artola and Kristin Böhlig (who made the cover). Link to article: www.nature.com/articles/s41...
October 9, 2025 at 9:01 AM
Lipid imaging on the cover of @nature.com! Great times for lipid cell biology indeed. And a fantastic recognition of all the hard work by the team, especially Juan M. Iglesias-Artola and Kristin Böhlig (who made the cover). Link to article: www.nature.com/articles/s41...
Reposted by Giovanni D’Angelo
Happy to finally see The Lipid Brain Atlas out! Lipids are not boring at all so, check it out!
Amazing team effort between computational and experimental work, led by @lucafusarbassini.bsky.social with @gioelelamanno.bsky.social and @giodang.bsky.social labs. Proud to be part of it.
Lipids rule!
Amazing team effort between computational and experimental work, led by @lucafusarbassini.bsky.social with @gioelelamanno.bsky.social and @giodang.bsky.social labs. Proud to be part of it.
Lipids rule!
🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution.
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
October 16, 2025 at 12:32 PM
Happy to finally see The Lipid Brain Atlas out! Lipids are not boring at all so, check it out!
Amazing team effort between computational and experimental work, led by @lucafusarbassini.bsky.social with @gioelelamanno.bsky.social and @giodang.bsky.social labs. Proud to be part of it.
Lipids rule!
Amazing team effort between computational and experimental work, led by @lucafusarbassini.bsky.social with @gioelelamanno.bsky.social and @giodang.bsky.social labs. Proud to be part of it.
Lipids rule!
This is a massive undertaking by a courageous group of experimentalists and computational scientists. I am honored to have contributed to this. #lipidtime chenges time zone today
🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution.
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
October 16, 2025 at 7:35 AM
This is a massive undertaking by a courageous group of experimentalists and computational scientists. I am honored to have contributed to this. #lipidtime chenges time zone today
So deserved!!!
I am deeply honoured to have been recognized by the European Research Council with a #StartingGrant. @erc.europa.eu
With this support, my team and I will launch #MOVIOLA. Our goal is to understand how human neural progenitors decide their fate during brain development.
With this support, my team and I will launch #MOVIOLA. Our goal is to understand how human neural progenitors decide their fate during brain development.
Two life sciences ERC Starting Grants at EPFL
Milena Schuhmacher and Gioele La Manno at EPFL’s School of Life Sciences have received European Research Council (ERC) Starting Grants. Former EPFL researcher Can Aztekin (now at Max Planck), is also ...
actu.epfl.ch
September 5, 2025 at 7:54 AM
So deserved!!!
Congrats Milena… I wish I was there with you when this was announced….
So honored to be awarded the ERC Starting Grant! I am very grateful for this support and looking forward to more exciting #lipidtime 🥳
Also, we will have positions available next year. So stay tuned!
Also, we will have positions available next year. So stay tuned!
📣 The ERC Starting Grant call results are out!
Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!
➡️ buff.ly/IsafuFh
#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!
➡️ buff.ly/IsafuFh
#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
September 5, 2025 at 7:53 AM
Congrats Milena… I wish I was there with you when this was announced….
Reposted by Giovanni D’Angelo
uMAIA offers an analytical framework designed to enable construction of high-resolution metabolic atlases using mass spec imaging data. @gioelelamanno.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Unified mass imaging maps the lipidome of vertebrate development - Nature Methods
uMAIA is an analytical framework designed to enable the construction of metabolic atlases at high resolution using mass spectrometry imaging data.
www.nature.com
September 3, 2025 at 4:59 PM
uMAIA offers an analytical framework designed to enable construction of high-resolution metabolic atlases using mass spec imaging data. @gioelelamanno.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Giovanni D’Angelo
Proud of these advances, achieved in great company @EPFL : @giodang.bsky.social (co-PI), with Halima Schede & Leila Alieh leading the project, and the Oates lab bringing their zebrafish expertise [2/2]
September 3, 2025 at 4:16 PM
Proud of these advances, achieved in great company @EPFL : @giodang.bsky.social (co-PI), with Halima Schede & Leila Alieh leading the project, and the Oates lab bringing their zebrafish expertise [2/2]
Happy to share our work on uMAIA, a framework for building metabolomic atlases from mass spectrometry imaging.
With uMAIA, we mapped the lipidome of zebrafish development, uncovering spatially organized metabolic programs .
www.nature.com/articles/s41...
#developmentalbiology #MSI #lipidtime
With uMAIA, we mapped the lipidome of zebrafish development, uncovering spatially organized metabolic programs .
www.nature.com/articles/s41...
#developmentalbiology #MSI #lipidtime
Unified mass imaging maps the lipidome of vertebrate development
Nature Methods - uMAIA is an analytical framework designed to enable the construction of metabolic atlases at high resolution using mass spectrometry imaging data.
www.nature.com
September 3, 2025 at 10:40 AM
Happy to share our work on uMAIA, a framework for building metabolomic atlases from mass spectrometry imaging.
With uMAIA, we mapped the lipidome of zebrafish development, uncovering spatially organized metabolic programs .
www.nature.com/articles/s41...
#developmentalbiology #MSI #lipidtime
With uMAIA, we mapped the lipidome of zebrafish development, uncovering spatially organized metabolic programs .
www.nature.com/articles/s41...
#developmentalbiology #MSI #lipidtime
Reposted by Giovanni D’Angelo
We are proud to be a founding contributor to lipidinteractome.org, a repository developed by @tafesselab.bsky.social & Schultz lab to increase accessibility to proteomics data from multi-functionalized lipid analogs! Check out the website & preprint: arxiv.org/abs/2507.23101 #lipidtime
The Lipid Interactome Repository – Lipid Interactome Repository
lipidinteractome.org
August 5, 2025 at 1:06 PM
We are proud to be a founding contributor to lipidinteractome.org, a repository developed by @tafesselab.bsky.social & Schultz lab to increase accessibility to proteomics data from multi-functionalized lipid analogs! Check out the website & preprint: arxiv.org/abs/2507.23101 #lipidtime
Reposted by Giovanni D’Angelo
A no-miss opportunity to join EPFL. We are a vibrant (had to use it 😉) community working in all branches of basic sciences and engineering, and interdisciplinary studies are strongly encouraged.
If you want more information, contact the committee heads, or feel free to DM me.
tinyurl.com/bd27ky7p
If you want more information, contact the committee heads, or feel free to DM me.
tinyurl.com/bd27ky7p
Assistant/associate Professor of AI-assisted Biophysics at the Ecole polytechnique fédérale de Lausanne (EPFL) and Group Leader at the Paul Scherrer Institute (PSI)
The School of Basic Sciences (Physics, Chemistry and Mathematics) at EPFL and the Paul Scherrer Institute (PSI) jointly seek to appoint a Tenure Track Assistant or tenured Associate Professor in AI-As...
tinyurl.com
August 21, 2025 at 6:35 AM
A no-miss opportunity to join EPFL. We are a vibrant (had to use it 😉) community working in all branches of basic sciences and engineering, and interdisciplinary studies are strongly encouraged.
If you want more information, contact the committee heads, or feel free to DM me.
tinyurl.com/bd27ky7p
If you want more information, contact the committee heads, or feel free to DM me.
tinyurl.com/bd27ky7p
Reposted by Giovanni D’Angelo
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 21, 2025 at 5:19 AM
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
We , @lbm-epfl.bsky.social and @gisouvggoot.bsky.social #EPFL together with and tf Sean Munro and John Briggs have today released two complementary preprints on GOLPH3 mediated intra-Golgi recycling
#CellBiology #MembraneTrafficking
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
#CellBiology #MembraneTrafficking
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Molecular Regulation and Physiological Role of 1 GOLPH3-mediated Golgi retention
The Golgi complex serves as the central hub of the biosynthetic pathway, where anterograde and retrograde trafficking converge. How cargo and Golgi-resident proteins traverse this organelle has long b...
www.biorxiv.org
June 27, 2025 at 8:35 PM
We , @lbm-epfl.bsky.social and @gisouvggoot.bsky.social #EPFL together with and tf Sean Munro and John Briggs have today released two complementary preprints on GOLPH3 mediated intra-Golgi recycling
#CellBiology #MembraneTrafficking
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
#CellBiology #MembraneTrafficking
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Giovanni D’Angelo
The joint FEBS Special Meeting on Sphingolipid Biology & 13th International Ceramide Conference is just one month away!!
Make sure to submit your abstract and register before the deadlines to secure your spot!
www.linkedin.com/events/febss...
Make sure to submit your abstract and register before the deadlines to secure your spot!
www.linkedin.com/events/febss...
FEBS Special Meeting on Sphingolipid Biology: breaking boundaries | LinkedIn
www.linkedin.com
April 24, 2025 at 4:10 PM
The joint FEBS Special Meeting on Sphingolipid Biology & 13th International Ceramide Conference is just one month away!!
Make sure to submit your abstract and register before the deadlines to secure your spot!
www.linkedin.com/events/febss...
Make sure to submit your abstract and register before the deadlines to secure your spot!
www.linkedin.com/events/febss...
This is very interesting
In today’s asymmetry news…
Why are biological membranes asymmetric, with different lipids in the two bilayer leaflets? Discovered in the 70s, lipid asymmetry is linked to many cellular processes, but why the cell needs it is largely unclear. @pavelbarahtjan.bsky.social addresses this question: www.biorxiv.org/content/10.1...
May 7, 2025 at 6:01 PM
This is very interesting
Wow
Thrilled to share LUNA🌕 – our new generative AI model that reassembles tissue structures from dissociated cells! LUNA learns spatial priors over existing spatially resolved datasets with the aim to predict cell locations de novo.
Check out our paper here: www.biorxiv.org/content/10.1...
Check out our paper here: www.biorxiv.org/content/10.1...
February 27, 2025 at 11:58 AM
Wow
Reposted by Giovanni D’Angelo
Round tables are an important part of the FEBS Sphingolipid meetings and we are very excited to announce that Nikon
will be sponsoring a "Women in Science" themed discussion at FEBS 2025/ICC 13. Let us know below what other subjects you would like to discuss!
will be sponsoring a "Women in Science" themed discussion at FEBS 2025/ICC 13. Let us know below what other subjects you would like to discuss!
February 13, 2025 at 2:43 PM
Round tables are an important part of the FEBS Sphingolipid meetings and we are very excited to announce that Nikon
will be sponsoring a "Women in Science" themed discussion at FEBS 2025/ICC 13. Let us know below what other subjects you would like to discuss!
will be sponsoring a "Women in Science" themed discussion at FEBS 2025/ICC 13. Let us know below what other subjects you would like to discuss!
Reposted by Giovanni D’Angelo
Amazing review to learn about single-cell lipid biology ! Congratulations to all authors @antonino-asaro.bsky.social @Agostina Crotta Asis @giodang.bsky.social published in @cp-trendscellbio.bsky.social !
www.cell.com/trends/cell-...
www.cell.com/trends/cell-...
Single cell lipid biology
Lipids are major cell constituents endowed with astonishing structural diversity.
The pathways responsible for the assembly and disposal of different lipid species
are energetically demanding, and gen...
www.cell.com
January 16, 2025 at 1:46 PM
Amazing review to learn about single-cell lipid biology ! Congratulations to all authors @antonino-asaro.bsky.social @Agostina Crotta Asis @giodang.bsky.social published in @cp-trendscellbio.bsky.social !
www.cell.com/trends/cell-...
www.cell.com/trends/cell-...
Reposted by Giovanni D’Angelo
Making news!😎 congrats guys!! www.rts.ch/info/science...
December 18, 2024 at 4:23 PM
Making news!😎 congrats guys!! www.rts.ch/info/science...
Reposted by Giovanni D’Angelo
Judith's magnum opus from her postdoc in our lab: a genome-integrated massively parallel reporter assay for quantitative insights into enhancer-promoter communication, AI benchmarking, variant dissection, & promoter motif characterization. It will be the foundation of her new lab @USC, Jan 2025! 🚀
Finally out! We present EXTRA-seq, a new EXTended Reporter Assay to quantify endogenous enhancer-promoter communication at kb scale!
www.biorxiv.org/content/10.1...
A 🧵about what it can do:
#SynBio #DeepLearning #GeneRegulation
www.biorxiv.org/content/10.1...
A 🧵about what it can do:
#SynBio #DeepLearning #GeneRegulation
EXTRA-seq: a genome-integrated extended massively parallel reporter assay to quantify enhancer-promoter communication
Precise control of gene expression is essential for cellular function, but the mechanisms by which enhancers communicate with promoters to coordinate this process are not fully understood. While seque...
biorxiv.org
December 17, 2024 at 12:58 PM
Judith's magnum opus from her postdoc in our lab: a genome-integrated massively parallel reporter assay for quantitative insights into enhancer-promoter communication, AI benchmarking, variant dissection, & promoter motif characterization. It will be the foundation of her new lab @USC, Jan 2025! 🚀