@gbadegesinlab.bsky.social
Pediatric Kidney Doc, Kidney Genomics, Physician Scientist & Associate Dean for Physician Scientist Development @DukeMedSchool.bsky.social
Harnessing genomic tools to uncover safe, effective & durable therapies for nephrotic syndrome
Harnessing genomic tools to uncover safe, effective & durable therapies for nephrotic syndrome
Pinned
The final version of our paper www.nejm.org/doi/10.1056/... One APOL1 risk variant is associated with CKD & FSGS. We have a solid basis for new mechanistic studies in our journey to find durable cure for APOL1 KD @opeyemiolabisi.bsky.social @kidneyomicsamps.bsky.social @genetickidneydoc.bsky.social
Reposted
Thank you @opeyemiolabisi.bsky.social and the whole @dukekidney.bsky.social , @gbadegesinlab.bsky.social , Laura Barisoni et al!
It was a great couple of days of scientific excellence mixed with pleasant company and nice weather.
#APOL1 #FSGS #rFSGS #genetics #pediatrics #NephSky #SkyNeph #Medsky
It was a great couple of days of scientific excellence mixed with pleasant company and nice weather.
#APOL1 #FSGS #rFSGS #genetics #pediatrics #NephSky #SkyNeph #Medsky
It was a pleasure to have Dr. Sanna-Cherchi @genetickidneydoc.bsky.social give an excellent, well-attended, Renal Grand Rounds at @dukekidney.bsky.social He is an embodiment of collaborative excellence💪🏾 @columbiakidney.bsky.social
August 18, 2025 at 9:38 PM
Thank you @opeyemiolabisi.bsky.social and the whole @dukekidney.bsky.social , @gbadegesinlab.bsky.social , Laura Barisoni et al!
It was a great couple of days of scientific excellence mixed with pleasant company and nice weather.
#APOL1 #FSGS #rFSGS #genetics #pediatrics #NephSky #SkyNeph #Medsky
It was a great couple of days of scientific excellence mixed with pleasant company and nice weather.
#APOL1 #FSGS #rFSGS #genetics #pediatrics #NephSky #SkyNeph #Medsky
We have the momentum, let’s solve the problems of rFSGS, first step is to have critical mass of patients’ derived biomaterials to start answering fundamental questions that will lead us to better understanding of disease mechanisms and durable therapy🙏🏽
Our #rFSGS biobank is growing and we welcome patients from all over the world! Please reach out to us if you are a patient or a physician caring for one. We are creating a resource for everyone to use with the goal of resolving this disease and find new cures.
#KidneyMonth2025 #RareDisease #genetics
#KidneyMonth2025 #RareDisease #genetics
Building a biobank is key to finding new treatments for Recurrent Focal Segmental Glomerulosclerosis. If you or someone you know has #rFSGS and you want to learn how you can help by providing a biosample, email mb5150@cumc.columbia.edu.
#KidneyMonth #KidneyTransplant #nephsky #medsky #skyneph
#KidneyMonth #KidneyTransplant #nephsky #medsky #skyneph
March 18, 2025 at 10:34 PM
We have the momentum, let’s solve the problems of rFSGS, first step is to have critical mass of patients’ derived biomaterials to start answering fundamental questions that will lead us to better understanding of disease mechanisms and durable therapy🙏🏽
Happy to share this excellent editorial on our recent NEJM paper www.nejm.org/doi/10.1056/... by Simone @genetickidneydoc.bsky.social Simone you nailed it! www.nejm.org/doi/10.1056/... 🙏🏽
APOL1 Kidney Disease Variants — Information from West Africa at Last | NEJM
Chronic kidney disease (CKD) has a devastating effect on populations of African ancestry
worldwide and disproportionately affects persons in West African countries,1 in whom
CKD, once present, ofte...
www.nejm.org
January 17, 2025 at 5:43 PM
Happy to share this excellent editorial on our recent NEJM paper www.nejm.org/doi/10.1056/... by Simone @genetickidneydoc.bsky.social Simone you nailed it! www.nejm.org/doi/10.1056/... 🙏🏽
Our initial observations in @dukepump.bsky.social a program addressing the workforce crisis in uronephrology. journals.lww.com/cjasn/fullte... Take home: program is feasible, student feelings of id as BioMed researcher up!! We are excited with these baby steps #NIDDK @asnkidney.bsky.social #ASPN 👏
Addressing the Workforce Crisis in Uronephrology: Design... : Clinical Journal of the American Society of Nephrology
An abstract is unavailable.
journals.lww.com
January 17, 2025 at 1:02 AM
Our initial observations in @dukepump.bsky.social a program addressing the workforce crisis in uronephrology. journals.lww.com/cjasn/fullte... Take home: program is feasible, student feelings of id as BioMed researcher up!! We are excited with these baby steps #NIDDK @asnkidney.bsky.social #ASPN 👏
Happynew year College Students!! We are accepting applications for tthe Duke PUMP. A summer research and immersion program to address the workforce crisis and diversify the workforce in Uronephrology. Spend & enjoy a summer of science at Duke. Link for application duke.qualtrics.com/jfe/form/SV_...
January 6, 2025 at 10:27 PM
Happynew year College Students!! We are accepting applications for tthe Duke PUMP. A summer research and immersion program to address the workforce crisis and diversify the workforce in Uronephrology. Spend & enjoy a summer of science at Duke. Link for application duke.qualtrics.com/jfe/form/SV_...
Reposted
Just saw this paper which says that APOL1 channel activity drives podocyte injury, and that small molecule APOL1 inhibitors are beneficial in a mouse model of APOL1-mediated CKD...intriguing: www.nature.com/articles/s41...
Small molecule APOL1 inhibitors as a precision medicine approach for APOL1-mediated kidney disease - Nature Communications
Apolipoprotein L1 genetic variants contribute to a subtype of proteinuric kidney disease referred to as APOL1-mediated kidney disease (AMKD). Here the authors report the discovery and characterization...
www.nature.com
January 3, 2025 at 7:00 PM
Just saw this paper which says that APOL1 channel activity drives podocyte injury, and that small molecule APOL1 inhibitors are beneficial in a mouse model of APOL1-mediated CKD...intriguing: www.nature.com/articles/s41...
Reposted
Glucose metabolism pathway
December 27, 2024 at 4:45 AM
Glucose metabolism pathway
Reposted
Welcome @dukepump.bsky.social
Please welcome Duke PUMP to Bluesky. This is a summer research program set up to address workforce crisis in uronephrology @dukeopsd.bsky.social @opeyemiolabisi.bsky.social @kidneyomicsamps.bsky.social @genetickidneydoc.bsky.social #NIDDK #ASPN @dukectsi.bsky.social
December 23, 2024 at 10:14 PM
Welcome @dukepump.bsky.social
Duke PUMP is our effort to address the workforce crisis in Nephrology& urology. We are accepting applications for our 3rd cohort. Only 37% of positions filled in Peds Neph this year!! We should engage young folks in career in Neph from elementary school!! #NIDDK #ASPN @asnkidney.bsky.social
December 19, 2024 at 8:11 PM
Duke PUMP is our effort to address the workforce crisis in Nephrology& urology. We are accepting applications for our 3rd cohort. Only 37% of positions filled in Peds Neph this year!! We should engage young folks in career in Neph from elementary school!! #NIDDK #ASPN @asnkidney.bsky.social
Amazing, the story of the humble beginning of Congressman Shri Thanedar of Michigan @shrithanedar.bsky.social The only Pharmaceutics researcher in Congress. In him we have a huge champion for #rFSGS @rfsgsinitiative.bsky.social @kidneyomicsamps.bsky.social @genetickidneydoc.bsky.social
December 9, 2024 at 8:13 PM
Amazing, the story of the humble beginning of Congressman Shri Thanedar of Michigan @shrithanedar.bsky.social The only Pharmaceutics researcher in Congress. In him we have a huge champion for #rFSGS @rfsgsinitiative.bsky.social @kidneyomicsamps.bsky.social @genetickidneydoc.bsky.social
Great meeting!! Tough problem(s) requiring great minds and stakeholders with “can do attitude”. Amazing listening to Congresswoman Haley Stevens of Michigan linking biomedical research and workforce development to National defense!! @rfsgsinitiative.bsky.social
The epitome of a Physician-Scientist. @gbadegesinlab.bsky.social swoops in to DC this morning from being on call last night in North Carolina to moderate an early session here at @rfsgsinitiative.bsky.social
December 9, 2024 at 5:37 PM
Great meeting!! Tough problem(s) requiring great minds and stakeholders with “can do attitude”. Amazing listening to Congresswoman Haley Stevens of Michigan linking biomedical research and workforce development to National defense!! @rfsgsinitiative.bsky.social
Reposted
Three must read papers for PhD students. #scisky #PhD #science #research #academicsky
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
November 24, 2024 at 1:54 PM
Three must read papers for PhD students. #scisky #PhD #science #research #academicsky
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
Match day!! Huge workforce crisis in Peds Nephrology, only 20% of program filled second to the last overall. We need urgent intervention #ASPN #NIDDK #AAP #ASN @atomickidney.bsky.social @jostflynnmd.bsky.social @asouth-neph.bsky.social @kidneyomicsamps.bsky.social @rheaultm.bsky.social
December 7, 2024 at 2:23 AM
Match day!! Huge workforce crisis in Peds Nephrology, only 20% of program filled second to the last overall. We need urgent intervention #ASPN #NIDDK #AAP #ASN @atomickidney.bsky.social @jostflynnmd.bsky.social @asouth-neph.bsky.social @kidneyomicsamps.bsky.social @rheaultm.bsky.social
Reposted
Writing a scientific article: A step-by-step guide for beginners
Main sections that an average article should contain; the elements that should appear in these sections, and some pointers for making the overall result attractive and acceptable for publication.
www.sciencedirect.com/science/arti...
Main sections that an average article should contain; the elements that should appear in these sections, and some pointers for making the overall result attractive and acceptable for publication.
www.sciencedirect.com/science/arti...
December 6, 2024 at 11:32 AM
Writing a scientific article: A step-by-step guide for beginners
Main sections that an average article should contain; the elements that should appear in these sections, and some pointers for making the overall result attractive and acceptable for publication.
www.sciencedirect.com/science/arti...
Main sections that an average article should contain; the elements that should appear in these sections, and some pointers for making the overall result attractive and acceptable for publication.
www.sciencedirect.com/science/arti...
Reposted
How to write a good scientific review article. #PhD #scisky #medsky
Open Access
febs.onlinelibrary.wiley.com/doi/10.1111/...
Open Access
febs.onlinelibrary.wiley.com/doi/10.1111/...
December 4, 2024 at 11:11 AM
How to write a good scientific review article. #PhD #scisky #medsky
Open Access
febs.onlinelibrary.wiley.com/doi/10.1111/...
Open Access
febs.onlinelibrary.wiley.com/doi/10.1111/...
Bluesky community, please welcome @dukeopsd.bsky.social This is an innovative centralized PSTP program @dukemedschool.bsky.social It leverage & extend access to research & career support for Trainees & Young Investigators. Please follow us🙏🏽
December 3, 2024 at 9:24 PM
Bluesky community, please welcome @dukeopsd.bsky.social This is an innovative centralized PSTP program @dukemedschool.bsky.social It leverage & extend access to research & career support for Trainees & Young Investigators. Please follow us🙏🏽
Nephrology and Transplant community please welcome Krista @kristalentine.bsky.social to bsky @kidneyomicsamps.bsky.social @rfsgsinitiative.bsky.social @rheaultm.bsky.social @nephrosparks.bsky.social @mcstarr1.bsky.social @atomickidney.bsky.social @mannonmom.bsky.social
Hello bsky community of biomedical researchers, nephrologists, transplant nephrologists, Please welcome and follow @kristalentine.bsky.social giant and thought leader in transplant research, #APOLLO @the-asci.bsky.social @asnkidney.bsky.social @opeyemiolabisi.bsky.social 🙏🏽
November 29, 2024 at 1:58 AM
Nephrology and Transplant community please welcome Krista @kristalentine.bsky.social to bsky @kidneyomicsamps.bsky.social @rfsgsinitiative.bsky.social @rheaultm.bsky.social @nephrosparks.bsky.social @mcstarr1.bsky.social @atomickidney.bsky.social @mannonmom.bsky.social
Hello bsky community of biomedical researchers, nephrologists, transplant nephrologists, Please welcome and follow @kristalentine.bsky.social giant and thought leader in transplant research, #APOLLO @the-asci.bsky.social @asnkidney.bsky.social @opeyemiolabisi.bsky.social 🙏🏽
November 28, 2024 at 8:39 PM
Hello bsky community of biomedical researchers, nephrologists, transplant nephrologists, Please welcome and follow @kristalentine.bsky.social giant and thought leader in transplant research, #APOLLO @the-asci.bsky.social @asnkidney.bsky.social @opeyemiolabisi.bsky.social 🙏🏽
Reposted
🚨 We are officially two weeks out from the #rFSGSConference! 🚨
Reserve your spot so you can join us in Washington, DC to discuss #rFSGS research, funding, and treatments. Register today: www.scgcorp.com/rFSGS2024/Re...
Reserve your spot so you can join us in Washington, DC to discuss #rFSGS research, funding, and treatments. Register today: www.scgcorp.com/rFSGS2024/Re...
November 26, 2024 at 2:05 AM
🚨 We are officially two weeks out from the #rFSGSConference! 🚨
Reserve your spot so you can join us in Washington, DC to discuss #rFSGS research, funding, and treatments. Register today: www.scgcorp.com/rFSGS2024/Re...
Reserve your spot so you can join us in Washington, DC to discuss #rFSGS research, funding, and treatments. Register today: www.scgcorp.com/rFSGS2024/Re...
rFSGS is a major cause of kidney tx loss in FSGS. Join us on Dec 9th in DC with pts and other major stakeholders in the room to discuss how we can harness modern tools to address this area of need @kidneyomicsamps.bsky.social @genetickidneydoc.bsky.social #alessiafornoni @opeyemiolabisi.bsky.social
The Recurrent Focal Segmental Glomerulosclerosis (#rFSGS) Conference is on Dec. 9 in Washington, DC! The #rFSGSConference program is led by groundbreaking researchers in the field & designed for patients & advocates, to learn from & connect with one another! Register: www.scgcorp.com/rFSGS2024/Re...
November 24, 2024 at 9:47 PM
rFSGS is a major cause of kidney tx loss in FSGS. Join us on Dec 9th in DC with pts and other major stakeholders in the room to discuss how we can harness modern tools to address this area of need @kidneyomicsamps.bsky.social @genetickidneydoc.bsky.social #alessiafornoni @opeyemiolabisi.bsky.social
Check out the final version of this paper in AJT focusing on genetic evaluation of kidney transplant candidates. www.sciencedirect.com/science/arti... Thanks Christie Thomas #UniIowa for leading the efforts and all the Co-Authors.
Evaluation for genetic disease in kidney transplant candidates: A practice resource
The increasing availability of clinically approved genetic tests for kidney disease has spurred the growth in the use of these tests in kidney transpl…
www.sciencedirect.com
November 24, 2024 at 9:12 PM
Check out the final version of this paper in AJT focusing on genetic evaluation of kidney transplant candidates. www.sciencedirect.com/science/arti... Thanks Christie Thomas #UniIowa for leading the efforts and all the Co-Authors.
@altmetric.com please add @bsky.social mention to your journal article metrics. All researchers especially biomedical researchers, love this❤️ to send the message loud and clear. @opeyemiolabisi.bsky.social @genetickidneydoc.bsky.social @kidneydoc101.bsky.social
November 23, 2024 at 10:45 PM
@altmetric.com please add @bsky.social mention to your journal article metrics. All researchers especially biomedical researchers, love this❤️ to send the message loud and clear. @opeyemiolabisi.bsky.social @genetickidneydoc.bsky.social @kidneydoc101.bsky.social
Reposted
Ethylene glycol intoxication presents w/ anion gap metabolic acidosis & acute oxalate tubulopathy. Detection of urinary calcium oxalate monohydrate crystals helps in diagnosis [not classic dumbbell nor envelope shaped (dihydrate) but rather “cigar” shaped]. Slide courtesy of @jrseltzer.bsky.social
November 22, 2024 at 10:27 PM
Ethylene glycol intoxication presents w/ anion gap metabolic acidosis & acute oxalate tubulopathy. Detection of urinary calcium oxalate monohydrate crystals helps in diagnosis [not classic dumbbell nor envelope shaped (dihydrate) but rather “cigar” shaped]. Slide courtesy of @jrseltzer.bsky.social
@altmetric.com please add @bsky.app mention to your journal article metrics. All researchers especially biomedical researchers, love this❤️ to send the message loud and clear. @opeyemiolabisi.bsky.social @genetickidneydoc.bsky.social @kidneydoc101.bsky.social
November 23, 2024 at 10:09 PM
@altmetric.com please add @bsky.app mention to your journal article metrics. All researchers especially biomedical researchers, love this❤️ to send the message loud and clear. @opeyemiolabisi.bsky.social @genetickidneydoc.bsky.social @kidneydoc101.bsky.social