#APOL1
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jwaitz.bsky.social
Povetacicept! I’m excited to see some new IgA data from everyone at #kidneywk but ApoL1 is still my one true love

#nephjc
October 29, 2025 at 1:07 AM
jenna-m-norton.bsky.social
On 20 March 2025, Trump’s NIH terminated a grant exploring structural racism as a second hit on APOL1 in kidney disease.

The majority of the patients on the study’s stakeholder advisory board heard this as: ‘Your life does not matter to us’.

www.nature.com/articles/s41...
Harms of terminating NIH grants for kidney disease - Nature Reviews Nephrology
In early 2025, nearly 2,100 research projects funded by the US National Institutes of Health (NIH) were terminated. Numerous calls for depoliticization of the NIH’s scientific mission culminated in th...
www.nature.com
October 21, 2025 at 4:01 AM
genetickidneydoc.bsky.social
Exciting expansion!!
#FSGS #APOL1
October 3, 2025 at 1:35 PM
hswapnil.medsky.social
Absolutely

Off topic - but Glipination, flozination, IgA treatments APOL1 progress are way more exciting than immune tolerance right now

#NephJC
October 1, 2025 at 1:15 AM
oalavijeh.bsky.social
🚨 New paper alert 🚨

Proud to share our work in AJKD: “Quantifying APOL1, HLA, and other genetic contributions to unexplained kidney failure”

What drives kidney failure when the cause is unknown? 🧵

www.ajkd.org/article/S027...
Quantifying APOL1, Human Leukocyte Antigen, and Other Genetic Contributions to Unexplained Kidney Failure
Unexplained kidney failure (uKF) affects 15% of individuals needing kidney replacement therapy. The lack of a clear diagnosis creates uncertainty about recurrence, familial risk, and trial eligibility...
www.ajkd.org
September 28, 2025 at 9:58 PM
glomcon.org
Join GlomCon this Sunday

APOL1 Kidney Disease: Genetic Basis and its Modifications by Dr. Simone Sanna-Cherchi

ID: 875 5077 1266
Passcode 202122

sign up 👉 bit.ly/signup-glomcon

#GlomCon
March 4, 2025 at 4:18 PM
jenniejlin.bsky.social
High impact papers
On renal APOL1
Could win big this year

#NephMadness #MedHaiku
@NephMadness @AJKDonline
November 23, 2024 at 1:32 AM
jenniejlin.bsky.social
First up is Dr. Reidy, who is discussing "#APOL1 from a Prenatal, Perinatal, and Pediatric Perspective." #KidneyWk
November 21, 2024 at 7:59 PM
nephroseeker.medsky.social
4/Prevalence of APOL1 HRG
~50% in some of African countries
📍Variable other regions but considerably higher than
13% in AAs
#kidnewk
November 16, 2024 at 2:38 PM
kristalentine.bsky.social
Honored to join w/ @CoachDC_32 in sharing 🙌🏾 w/ our community on 2 projects related to #APOL1 gene underway at @SLUHospital🏥
1⃣ @midamtransplant-supported study in our #Nephrology clinics
2⃣ @NIH-supported #APOLLO #kidneytransplant study
🙏🏾Learn more 📢 https://t.co/a4Ywj1dFey https://t.co/aKp9qr3Mnl
November 28, 2024 at 7:38 AM
kristalentine.bsky.social
🙏🏾Honored to talk w/@drebjournalist on @stlpublicradio🎙️about racial #disparities in #KidneyTransplant outcomes➕how studies like @NIDDKgov-funded #APOLLO (#APOL1 #KidneyTransplant Outcomes) seek to understand & inform ways to improve those outcomes🙌🏾
•📲

news.stlpublicradio.org/health-science…
SLU doctors urge Black people to enter kidney research to boost transplant outcomes
Members of the kidney transplant team at St. Louis University Hospital say including more Black people in kidney research and as donors could help address racial disparities in transplant outcomes.
news.stlpublicradio.org
November 28, 2024 at 8:32 AM
kristalentine.bsky.social
🙏🏾@SRTRNews for collaboration –‘How Long is Wait Worthwhile? Cost-effectiveness 💰of accepting a Kidney from a Donor w/ #APOL1 High-Risk Genotype’ available on #SRTR channel
• #ATC2021Virtual | #Kidney #DonorSelection | @SuhsinChang | @SLUHospital
📲▶️

youtu.be/OMrq5CkXfMA
How Long is the Wait Worthwhile?
Cost-Effectiveness of Accepting a Kidney from a Donor with Apolipoprotein L1 High-Risk Genotype
youtu.be
November 28, 2024 at 8:29 AM
albadocherty.bsky.social
Understanding Adaptive and Innate Immune Cell Dysfunction in Patients with PASC Purvesh Khatri Viral and Host Genomics Influences on the Phenotypic Expression of COVID-19 Infection and Its Sequelae in Children of Varied Genetic Ancestries Sindhu Mohandas Cerebral Vascular Pathology of COVID-19 Michal Toborek Cerebrospinal Fluid in PASC: A Window into the COVID Mind Serena S. Spudici Deciphering the Link Between Severe Acute Respiratory Coronavirus 2 Infection and Long-Term Neurological and Pulmonary Sequelae Xin Sun NOSI Elucidating Genetic and Environmental Second Hits in Racial and Ethnic Minorities with APOL1 High-Risk Genotypes Nadkarni Epigenetic Alterations and Phenotypes in Innate Immune Cells and Their Progenitors in PASC Steven Zvi JosefowiczFeatures and Functions of ACE2 Autoantibodies that Developed after SARS-CoV-2 Infection Bradley Imaging Neuroglial Mechanisms of Neuropathic Pain-Opioid Interaction in HIV Luciano Loggi Leptin Reduction as a Potent Mitigative Strategy
March 28, 2025 at 1:31 PM
taghivscience.bsky.social
APOL1 genotype and patient outcomes in US and South African transplant recipients with #HIV who received kidneys from donors with HIV www.medrxiv.org/content/10.1... (open access preprint) @medrxivpreprint.bsky.social
APOL1 genotype and patient outcomes in US and South African transplant recipients with HIV who received kidneys from donors with HIV
Importance Lower kidney allograft survival has been demonstrated in kidney transplant recipients (KTR) without HIV whose donors have two apolipoprotein L1 ( APOL1 ) renal risk variants (RRV). The effe...
www.medrxiv.org
May 5, 2025 at 2:34 PM
ooh, wow!, thanks!, that’s coool- I didn’t know that it was Apol1 awareness day!!, 👀🤓🙏💛
April 30, 2025 at 1:29 AM
infosalus.com
Un organoide renal revela la causa genética de la enfermedad renal crónica mediada por APOL1
Un organoide renal revela la causa genética de la enfermedad renal crónica mediada por APOL1
www.infosalus.com
October 3, 2025 at 3:06 PM
kristalentine.bsky.social
Honored to be part of the #APOLLO Consortium➕to participate in this #FacebookLive event panel 🎙️on clinical implications of #APOL1 genotyping in #transplantation 🙌🏾
•🙏🏾 @SLUHospital | @slusom | @SLUHealthNews | @SLUResearch | @itsglendar | @sylviaerosas | @NIDDKgov | @nkf 💙💚 https://t.co/jIiOErO44X
November 28, 2024 at 7:38 AM
grahamabra.bsky.social
sFLT is sorta like Steve Fisher at SDSU, good coach but greatness was a number of years ago. APOL1 FTW! #NephMadness
November 16, 2024 at 5:32 AM
grahamabra.bsky.social
Tsetse fly, Trypanosoma brucei rhodesiense, African sleeping sickness. FSGS/HIVAN. APOL1 dominates to the Elite8. #NephMadness
November 16, 2024 at 5:27 AM
kinetoplastpapers.bsky.social
Sodium-glucose co-transporter inhibitors for APOL1 kidney disease: A call for studies pubmed.ncbi.nlm.nih.gov/40038200/
March 5, 2025 at 3:10 PM
kidneyboy.bsky.social
This looks pretty good.

Diagnosing APOL1-Mediated Kidney Disease (AMKD) | HCP https://www.apol1ckd.com/
Access Denied
www.apol1ckd.com
November 24, 2024 at 8:10 AM
nephroseeker.medsky.social
4/ But how APOL1 can cause CKD?
The development of focal segmental glomerulosclerosis (FSGS), which is a leading cause of end-stage kidney disease (ESKD) in African Americans, characterizes APOL1-mediated nephropathy
#NephJC
https://pubmed.ncbi.nlm.nih.gov/35217848/
November 17, 2024 at 10:13 AM
hozzl.com
Bill Alert!
US House Bill HRES 360 - Expressing support for the designation of the last Tuesday of April each year as "APOL1-Mediated Kidney Disease (AMKD) Awareness Day".

Policy: Health

Full Details: https://hozzl.com/p/bill/119-hres-bill-number-360-expressing-support-for-the-designation-of-th...
May 9, 2025 at 6:25 PM
txkidneyfoundation.bsky.social
You can feel perfectly fine—and still have early, silent kidney damage.
APOL1 gene variants raise risk for Black, Afro-Caribbean & Afro-Latino communities.
Don’t wait for symptoms.
Ask your doctor for eGFR + uACR tests.
#AMKD #KidneyHealth #BlackHealthMatters
August 7, 2025 at 2:31 PM
dlingenfelter.bsky.social
COVID-19 can trigger severe kidney damage by indirectly injuring podocytes through systemic inflammation, especially in people with APOL1 high-risk genotypes.

This leads to collapsing glomerulopathy (COVAN), marked by rapid kidney failure and proteinuria.
gemini.google.com/share/b29476...
‎Gemini - COVID-19 Podocyte Injury and Proteinuria
Created with Gemini
gemini.google.com
September 14, 2025 at 3:39 PM