Gabrielle Brewer
@gabriellebrewer.bsky.social
Senior Editor at Nature Reviews Cancer.
@natrevcancer.bsky.social
🇨🇦 in Berlin,
part-time DIY fashion enthusiast 🧵
& full-time cat mom. 😸😸
Views are mine.
@natrevcancer.bsky.social
🇨🇦 in Berlin,
part-time DIY fashion enthusiast 🧵
& full-time cat mom. 😸😸
Views are mine.
October 27, 2025 at 9:21 AM
Reposted by Gabrielle Brewer
🚨 In light of the #NobelPrize recognizing discoveries in peripheral immune tolerance, our article "Regulatory T cells in the tumour microenvironment" is now free to read.
Discover how #Tregs shape cancer immunity 📖 👇
Discover how #Tregs shape cancer immunity 📖 👇
Regulatory T cells in the tumour microenvironment - Nature Reviews Cancer
This Review by Imianowski et al. outlines the various contributions that regulatory T cells, present in the tumour microenvironment, make towards tumour progression and highlight the ways in which they represent attractive next-generation immunotherapeutic targets.
bit.ly
October 17, 2025 at 3:25 PM
🚨 In light of the #NobelPrize recognizing discoveries in peripheral immune tolerance, our article "Regulatory T cells in the tumour microenvironment" is now free to read.
Discover how #Tregs shape cancer immunity 📖 👇
Discover how #Tregs shape cancer immunity 📖 👇
I am currently at BER waiting to board my flight to Portugal for #ESHAML2025! If you're attending too, I'd love to chat about
@natrevcancer.nature.com, editorial work in general or just to say hi 👋
@natrevcancer.nature.com, editorial work in general or just to say hi 👋
October 15, 2025 at 10:27 AM
I am currently at BER waiting to board my flight to Portugal for #ESHAML2025! If you're attending too, I'd love to chat about
@natrevcancer.nature.com, editorial work in general or just to say hi 👋
@natrevcancer.nature.com, editorial work in general or just to say hi 👋
Happy Thanksgiving to my fellow Canadians! 🍁🦃🥧
October 13, 2025 at 2:31 PM
Happy Thanksgiving to my fellow Canadians! 🍁🦃🥧
Even after finishing a PhD, the advise still resonated.
As an Editor, my advise: read A LOT🤓.
You don't need to reinvent the wheel to write a good paper... but you definitely need to slow down & think. Reading helps you contextualize findings, make good experimental plans & explain your science.
As an Editor, my advise: read A LOT🤓.
You don't need to reinvent the wheel to write a good paper... but you definitely need to slow down & think. Reading helps you contextualize findings, make good experimental plans & explain your science.
What's one piece of advice you'd give to someone considering a PhD?
We asked 3785 doctoral candidates across 107 countries for their hard-won wisdom
go.nature.com/4nDjJ7t
We asked 3785 doctoral candidates across 107 countries for their hard-won wisdom
go.nature.com/4nDjJ7t
27 things we wish we’d known when we started our PhDs
Nature’s survey of PhD candidates reveals hard-won wisdom on choosing supervisors, managing mental health and surviving academic culture.
go.nature.com
October 7, 2025 at 11:16 AM
Even after finishing a PhD, the advise still resonated.
As an Editor, my advise: read A LOT🤓.
You don't need to reinvent the wheel to write a good paper... but you definitely need to slow down & think. Reading helps you contextualize findings, make good experimental plans & explain your science.
As an Editor, my advise: read A LOT🤓.
You don't need to reinvent the wheel to write a good paper... but you definitely need to slow down & think. Reading helps you contextualize findings, make good experimental plans & explain your science.
T-ALL is notoriously hard to treat due to the difficulty in distinguishing normal and malignant T cells. Now Fuentes et al. identify the pre-TCR as a biomarker for leukemia-initiating cells and develop a targeted immunotherapy for it.
📖👇
📖👇
October 3, 2025 at 9:20 AM
T-ALL is notoriously hard to treat due to the difficulty in distinguishing normal and malignant T cells. Now Fuentes et al. identify the pre-TCR as a biomarker for leukemia-initiating cells and develop a targeted immunotherapy for it.
📖👇
📖👇
In a rare bout of personal news… I’m finally ready to be active on Bluesky again! Outside of my work-hours, I was a little busy planning a wedding with my cats’ dad 🐈🐈.
Photo evidence below 🤭
Photo evidence below 🤭
September 30, 2025 at 2:27 PM
In a rare bout of personal news… I’m finally ready to be active on Bluesky again! Outside of my work-hours, I was a little busy planning a wedding with my cats’ dad 🐈🐈.
Photo evidence below 🤭
Photo evidence below 🤭
Reposted by Gabrielle Brewer
Our FOCUS issue on #Ageing and Cancer is live!
It features articles on:
- age-induced metabolic reprogramming in cancer progression
- modelling ageing-related cancer evolution
- stromal senescence in age-related cancer
Read it now: http://bit.ly/48uIDB...
It features articles on:
- age-induced metabolic reprogramming in cancer progression
- modelling ageing-related cancer evolution
- stromal senescence in age-related cancer
Read it now: http://bit.ly/48uIDB...
September 24, 2025 at 2:02 PM
Our FOCUS issue on #Ageing and Cancer is live!
It features articles on:
- age-induced metabolic reprogramming in cancer progression
- modelling ageing-related cancer evolution
- stromal senescence in age-related cancer
Read it now: http://bit.ly/48uIDB...
It features articles on:
- age-induced metabolic reprogramming in cancer progression
- modelling ageing-related cancer evolution
- stromal senescence in age-related cancer
Read it now: http://bit.ly/48uIDB...
Reposted by Gabrielle Brewer
Our SEPTEMBER issue is live! 🌤️🍂🌻🍂
It features articles on:
- ER stress responses in anti-cancer immunity
- Regulatory T cells in the TME
- Metabolic adaptations of brain metastasis
- Engineering strategies for nanoparticles
Read it now👇
bit.ly/4mW1JnQ
It features articles on:
- ER stress responses in anti-cancer immunity
- Regulatory T cells in the TME
- Metabolic adaptations of brain metastasis
- Engineering strategies for nanoparticles
Read it now👇
bit.ly/4mW1JnQ
August 27, 2025 at 2:23 PM
Our SEPTEMBER issue is live! 🌤️🍂🌻🍂
It features articles on:
- ER stress responses in anti-cancer immunity
- Regulatory T cells in the TME
- Metabolic adaptations of brain metastasis
- Engineering strategies for nanoparticles
Read it now👇
bit.ly/4mW1JnQ
It features articles on:
- ER stress responses in anti-cancer immunity
- Regulatory T cells in the TME
- Metabolic adaptations of brain metastasis
- Engineering strategies for nanoparticles
Read it now👇
bit.ly/4mW1JnQ
Put on Tom & Jerry so my lil sidekick Leonard would let me work in peace. She was more into it than I thought she'd be 😹
August 19, 2025 at 11:14 AM
Put on Tom & Jerry so my lil sidekick Leonard would let me work in peace. She was more into it than I thought she'd be 😹
🤩 It was a pleasure handling this article, and I am equally excited to see it out! Congrats!!!
It’s out!!!!! We hope our review on aging, immunity, and cancer is helpful.
Such a rewarding group effort led by Melissa Dolan, with Kendra Libby, Alison Ringle, and @vangalenlab.bsky.social
So grateful to @gabriellebrewer.bsky.social @natrevcancer.nature.com for her efforts and support
Such a rewarding group effort led by Melissa Dolan, with Kendra Libby, Alison Ringle, and @vangalenlab.bsky.social
So grateful to @gabriellebrewer.bsky.social @natrevcancer.nature.com for her efforts and support
NEW content online!
August 15, 2025 at 2:15 PM
🤩 It was a pleasure handling this article, and I am equally excited to see it out! Congrats!!!
Exercise induces microbiota to produce formate which in turn enhances CD8+ T cell anti-tumour functionality. 💪 #gains
Check out my research highlight below for more deets 🤓🐛🧫
Check out my research highlight below for more deets 🤓🐛🧫
August 5, 2025 at 12:02 PM
Exercise induces microbiota to produce formate which in turn enhances CD8+ T cell anti-tumour functionality. 💪 #gains
Check out my research highlight below for more deets 🤓🐛🧫
Check out my research highlight below for more deets 🤓🐛🧫
Reposted by Gabrielle Brewer
#REVIEW 🚨
#Nanoparticles can be engineered for targeted delivery of cancer therapies. Gomerdinger, Nabar & Hammond explore how surface chemistry drives delivery, targeting & localization.
📖 👇
#Nanoparticles can be engineered for targeted delivery of cancer therapies. Gomerdinger, Nabar & Hammond explore how surface chemistry drives delivery, targeting & localization.
📖 👇
Advancing engineering design strategies for targeted cancer nanomedicine - Nature Reviews Cancer
Nanoparticle surfaces can be engineered for targeted delivery of cancer therapies. In this Review, Gomerdinger, Nabar and Hammond outline the role of surface chemistry at all levels of nanoparticle trafficking, from administration route, to tissue accumulation, cellular targeting and ultimately subcellular localization. They emphasize the utility of non-covalent surface modifications for improving stealth and targeting abilities of nanoparticles for cancer.
www.nature.com
August 4, 2025 at 3:39 PM
#REVIEW 🚨
#Nanoparticles can be engineered for targeted delivery of cancer therapies. Gomerdinger, Nabar & Hammond explore how surface chemistry drives delivery, targeting & localization.
📖 👇
#Nanoparticles can be engineered for targeted delivery of cancer therapies. Gomerdinger, Nabar & Hammond explore how surface chemistry drives delivery, targeting & localization.
📖 👇
August?! How did that happen?! I am still waiting for summer to arrive in Berlin😫
In any case, this issue is a goodie. Give it a read!! 🤓📖✨
In any case, this issue is a goodie. Give it a read!! 🤓📖✨
Our AUGUST issue is live! 🥵 🏖️ 🌞
It features:
- A #roadmap on acquire resistance in cancer
- A #persepective on gender and sex in cancer phenotypes
- A #review on neuro-immune crosstalk in cancer
- A #review on γδT cell signaling for cancer immunotherapy
It features:
- A #roadmap on acquire resistance in cancer
- A #persepective on gender and sex in cancer phenotypes
- A #review on neuro-immune crosstalk in cancer
- A #review on γδT cell signaling for cancer immunotherapy
Nature Reviews Cancer - Volume 25 Issue 8, August 2025
Sex and gender as a spectrum, inspired by the Perspective on p634.
bit.ly
July 30, 2025 at 12:44 PM
August?! How did that happen?! I am still waiting for summer to arrive in Berlin😫
In any case, this issue is a goodie. Give it a read!! 🤓📖✨
In any case, this issue is a goodie. Give it a read!! 🤓📖✨
Reposted by Gabrielle Brewer
In this Comment, Grünwald & Khokha call for a shift in comprehension of tumour tissue organization; while tumour tissues are heterogeneous, they are not disordered, & instead, propagate their functions via a considerable level of self-organization.
📖 👇
https://bit.ly/4nZaQ...
📖 👇
https://bit.ly/4nZaQ...
July 22, 2025 at 2:15 PM
In this Comment, Grünwald & Khokha call for a shift in comprehension of tumour tissue organization; while tumour tissues are heterogeneous, they are not disordered, & instead, propagate their functions via a considerable level of self-organization.
📖 👇
https://bit.ly/4nZaQ...
📖 👇
https://bit.ly/4nZaQ...
I previously volunteered w men returning from prison, where I saw how often adolescent hardships shaped their paths. Incarceration should not make someone undeserving of care & denying medical treatment reflects societal bias + ignorance.
📖⬇️ the barriers to equitable care for those behind bars.
📖⬇️ the barriers to equitable care for those behind bars.
People in the USA who are incarcerated, or have a history of incarceration, face worse access to cancer care, leading to poorer outcomes. Zhao & colleagues highlight the need to address these inequities through coordinated action.
https://www.nature.c...
https://www.nature.c...
July 21, 2025 at 3:21 PM
I previously volunteered w men returning from prison, where I saw how often adolescent hardships shaped their paths. Incarceration should not make someone undeserving of care & denying medical treatment reflects societal bias + ignorance.
📖⬇️ the barriers to equitable care for those behind bars.
📖⬇️ the barriers to equitable care for those behind bars.
A super cool Perspective highlighting the intersection of metabolic hallmarks of both aging and cancer.
In it, they also explore how population-related metabolic differences associated with longevity may contribute to racial disparities in cancer risk & prognosis.
Give it a read!! 🤓
In it, they also explore how population-related metabolic differences associated with longevity may contribute to racial disparities in cancer risk & prognosis.
Give it a read!! 🤓
#Perspective 🚨
Lazure and Gomes argue that metabolic changes that occur as a result of #ageing may shape tumour initiation and progression and the development of metastatic disease.
⬇️ 📖
https://bit.ly/3IkNY...
@moffittnews.bsky.social
Lazure and Gomes argue that metabolic changes that occur as a result of #ageing may shape tumour initiation and progression and the development of metastatic disease.
⬇️ 📖
https://bit.ly/3IkNY...
@moffittnews.bsky.social
Cancer progression through the lens of age-induced metabolic reprogramming - Nature Reviews Cancer
In this Perspective, Lazure and Gomes argue that metabolic changes that occur as a result of ageing may shape tumour initiation and progression and the development of metastatic disease.
bit.ly
July 21, 2025 at 7:02 AM
A super cool Perspective highlighting the intersection of metabolic hallmarks of both aging and cancer.
In it, they also explore how population-related metabolic differences associated with longevity may contribute to racial disparities in cancer risk & prognosis.
Give it a read!! 🤓
In it, they also explore how population-related metabolic differences associated with longevity may contribute to racial disparities in cancer risk & prognosis.
Give it a read!! 🤓
pictured here is Leonard watching me watch AACR talks 😹
July 18, 2025 at 3:05 PM
pictured here is Leonard watching me watch AACR talks 😹
I will absolutely never understand why you would actively choose to turn off spell check on your Word document.😫
Look, we all make mistakes even with spell check on.... but I can tell you without a doubt that it would *defiantely* benefit you to keep it on.
Look, we all make mistakes even with spell check on.... but I can tell you without a doubt that it would *defiantely* benefit you to keep it on.
July 17, 2025 at 12:59 PM
I will absolutely never understand why you would actively choose to turn off spell check on your Word document.😫
Look, we all make mistakes even with spell check on.... but I can tell you without a doubt that it would *defiantely* benefit you to keep it on.
Look, we all make mistakes even with spell check on.... but I can tell you without a doubt that it would *defiantely* benefit you to keep it on.
Check out my latest research highlight 👇
While the presence of tertiary lymphoid structures (TLSs) in tumours is often linked with ⬆️response to IO, the maturation status can influence this. Now, Tang et al. uncover tryptophan metabolism as a factor determining TLS maturation status.
While the presence of tertiary lymphoid structures (TLSs) in tumours is often linked with ⬆️response to IO, the maturation status can influence this. Now, Tang et al. uncover tryptophan metabolism as a factor determining TLS maturation status.
July 16, 2025 at 9:05 AM
Check out my latest research highlight 👇
While the presence of tertiary lymphoid structures (TLSs) in tumours is often linked with ⬆️response to IO, the maturation status can influence this. Now, Tang et al. uncover tryptophan metabolism as a factor determining TLS maturation status.
While the presence of tertiary lymphoid structures (TLSs) in tumours is often linked with ⬆️response to IO, the maturation status can influence this. Now, Tang et al. uncover tryptophan metabolism as a factor determining TLS maturation status.
Nature Cuteness 🥹
From Chief Editor of Nature Cuteness to Nap Quality Control Officer.
To give our colleagues a break to celebrate #SpringerNature10, we put the #PetsOfSN to work across our teams. All dogs, cats & bunnies were of course generously paid in tasty treats, belly rubs & cuddles.
#PetsOfSN10 🐶 🐱 🐰
To give our colleagues a break to celebrate #SpringerNature10, we put the #PetsOfSN to work across our teams. All dogs, cats & bunnies were of course generously paid in tasty treats, belly rubs & cuddles.
#PetsOfSN10 🐶 🐱 🐰
July 1, 2025 at 2:22 PM
Nature Cuteness 🥹
Reposted by Gabrielle Brewer
REVIEW🚨
Rodriguez, Cubillos-Ruiz &Co discuss how the #ERstress response affects intratumoural immune cells & highlight the potential of #UPR-targeted interventions to improve cancer outcomes.
👀⬇️
Rodriguez, Cubillos-Ruiz &Co discuss how the #ERstress response affects intratumoural immune cells & highlight the potential of #UPR-targeted interventions to improve cancer outcomes.
👀⬇️
Endoplasmic reticulum stress responses in anticancer immunity - Nature Reviews Cancer
The endoplasmic reticulum (ER) has a central role in mounting effective and durable antitumour immunity. In this Review, Hwang et al. outline how tumour-induced ER stress responses alter the function of intratumoural immune cells and the efficacy of immunotherapy, highlighting the potential of unfolded protein response-targeted interventions to improve cancer outcomes.
bit.ly
July 1, 2025 at 1:19 PM
A 'lil wknd readin' for ya 🤓🚨
Our July issue is LIVE! 🌞🥵🏖️
It features articles on:
- Targeted protein degradation for cancer therapy
- Advances in therapeutic cancer vaccines
- The TGFβ paradox in HPV-driven cancer
- The paths to metastasis
Happy reading! 👇 📖
https://www.nature.c...
It features articles on:
- Targeted protein degradation for cancer therapy
- Advances in therapeutic cancer vaccines
- The TGFβ paradox in HPV-driven cancer
- The paths to metastasis
Happy reading! 👇 📖
https://www.nature.c...
June 27, 2025 at 3:09 PM
A 'lil wknd readin' for ya 🤓🚨
Tbh, the Coral City Camera is easily my favourite account on bluesky. 😍
A nurse shark swerves at the last minute to avoid bonking the Cam! #nurseshark #sharksofcoralcity #shark #swerve #bonk #barbel #elasmobranch #coral #coralhead #coralcitycamera #miami #portmiami #biscaynebay #coralcity #civicpridethroughbiodiversity
June 16, 2025 at 9:33 AM
Tbh, the Coral City Camera is easily my favourite account on bluesky. 😍
Here's some Monday morning reading for you 🤓
🚨 In case you missed it... 🔁
In this #Review, Xiao & Puré outline the complexity of cancer-associated fibroinflammation and provide insights into its therapeutic targeting.
📖 👇
In this #Review, Xiao & Puré outline the complexity of cancer-associated fibroinflammation and provide insights into its therapeutic targeting.
📖 👇
The fibroinflammatory response in cancer - Nature Reviews Cancer
Fibroinflammation, a highly integrated fibrogenic and inflammatory response, is activated in response to tissue perturbation and thus contributes to tumour initiation, growth and metastasis. Here, Xiao and Puré outline the complexity of cancer-associated fibroinflammation and provide insights into its therapeutic targeting.
www.nature.com
June 16, 2025 at 8:18 AM
Here's some Monday morning reading for you 🤓