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foodallergyscience.org
Food Allergy Science Initiative
@foodallergyscience.org
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We accelerate the discovery of life-saving food allergy treatments.
A research engine uniting top scientists to bring breakthrough discoveries from bench to bedside. Powered by collaboration, driven by impact.

foodallergyscience.org
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Food Allergy Science Initiative @foodallergyscience.org · Apr 11
At FASI, we unite experts from top institutions to uncover the root causes of food allergies. By bridging immunology and neurobiology, we aim to stop allergic reactions before they start.

#foodallergy #research #neuroimmunology #prevention
foodallergyscience.org
Plot Twist: Food Allergies Might Not Start with Food
open.substack.com/pub/theunbia...
Plot Twist: Food Allergies Might Not Start with Food
Skin as Ground Zero: How a Broken Barrier Sparks Food Allergies
open.substack.com
November 19, 2025 at 3:05 PM
foodallergyscience.org
Thank you for highlighting this important discovery @snacksafely.bsky.social #foodallergy #immunosky #microbiomesky #medsky #pedsky #science
snacksafely.bsky.social SnackSafely @snacksafely.bsky.social · Aug 8
Exciting, potentially game-changing news in food allergy treatment! Researchers have found that an already FDA-approved drug for asthma blocked anaphylaxis in mice via a newly discovered pathway. #foodallergies
Asthma drug shows promise in blocking food allergy reactions
Study finds a new biological trigger for anaphylaxis and a drug that stops it
snacksafely.com
August 8, 2025 at 3:28 PM
Reposted by Food Allergy Science Initiative
science.org
In a recent #ScienceImmunology Review, researchers discuss how interactions between the nervous and immune systems could impact neurological disorders and allergy-related behaviors like food avoidance.

Learn more: scim.ag/4mpgzE5
A graphic showing that interactions between the nervous system and type 2 immunity occur across multiple organs depending on the context of allergic triggers or injury.
July 28, 2025 at 8:22 PM
Reposted by Food Allergy Science Initiative
erictopol.bsky.social
What is the mechanism of food-induced anaphylaxis?
Today @science.org unravelled
www.science.org/doi/full/10....
Gut mast cell leukotriene release
@rmedzhitov.bsky.social
August 7, 2025 at 8:06 PM
foodallergyscience.org
Why do some allergic reactions turn deadly—while others stay mild?

Two new @science.org papers, funded by @FASI and led by our researchers, uncover the gut–immune connection that may hold the answer. 🧵👇

#FoodAllergy #Anaphylaxis #immunosky #GutHealth #allergysky #medsky #microbiomesky
August 7, 2025 at 7:22 PM
Reposted by Food Allergy Science Initiative
cea01.bsky.social
Siglecs may hold the key to safer, more effective food allergy therapy. New findings show how targeting these immune receptors could reduce allergic reactions at the source. #FoodAllergy #Immunology #Siglecs

doi.org/10.1111/cea....
Exploring Siglecs: Potential Modulators of Immune Cells in Food Allergy and Therapeutic Applications
Sialic acid-binding immunoglobulin-type lectins (Siglecs) are inhibitory receptors present on all immune cells involved in the allergic reaction. Currently, research is mostly focussed on targeting S....
doi.org
July 31, 2025 at 2:19 PM
foodallergyscience.org
We are thrilled to have Dr. Nicholas Betley, Assistant Professor of Biology University of Pennsylvania join us at our 2025 Symposium.

Register today: foodallergyscience.org/fasi-symposi...

#immunosky #medsky #allergysky #science
August 1, 2025 at 9:14 PM
Reposted by Food Allergy Science Initiative
natureportfolio.nature.com
The Global Grants for Gut Health are now open. If your research explores how nutrition affects the gut #microbiome or barrier function, you may be eligible to apply for one of three grants each offering up to USD$100K. Apply here: go.nature.com/4kb9cO1 #Academicsky 🍎📃
July 16, 2025 at 4:00 PM
foodallergyscience.org
Join us on Friday, September 12th, 2025 for FASI’s 2025 Symposium!

To Register and view the agenda, Click Here: foodallergyscience.org/fasi-symposi...

#foodallergy #immunosky #allergysky #medsky
July 18, 2025 at 3:15 PM
Reposted by Food Allergy Science Initiative
drvantilburg.bsky.social
Big win for early allergen introduction! 🥜🍳👶 New guidelines on introducing allergenic foods to babies have drastically reduced food allergies—from 12% down to just 4% in high-risk infants. #FoodAllergy #PediatricHealth #EarlyFeeding #ParentingTips www.jaci-inpractice.org/article/S221...
www.jaci-inpractice.org
July 11, 2025 at 1:17 PM
Reposted by Food Allergy Science Initiative
lancetgastrohep.bsky.social
Our August issue is out now at www.thelancet.com/gastrohep!

Content includes Crohn’s disease, MASLD, faecal incontinence, variceal bleeding, food allergies, and more…

#GastroSky #LiverSky #MedSky #IBDSky
July 10, 2025 at 5:21 AM
Reposted by Food Allergy Science Initiative
boron110.bsky.social
In the latest ep of the @science.org Podcast I'm joined by researcher Sarita Patil. We talk about how "convergent” antibodies may underlie the growing number of people allergic to peanuts.

www.science.org/content/podc...
June 17, 2025 at 4:46 PM
foodallergyscience.org
We are thrilled to have Dr. Bradford Lowell, Professor of Medicine Beth Israel Deaconess Medical Center join us at our 2025 Symposium on September 12, 2025 at The Broad Institute of MIT and Harvard.

Register today: foodallergyscience.org/fasi-symposi...

#medsky #allergysky #immunosky
July 9, 2025 at 1:17 PM
Reposted by Food Allergy Science Initiative
drruth.bsky.social
🥜 Food Allergies may start in the Skin, not just the Gut🥜

Damaged skin (as with eczema) can let food proteins in, priming IgE responses that later trigger gut Mast Cells, which drives allergic reactions & anaphylaxis. buff.ly/Nfo06vB

#medsky #pedsky #foodallergy #immunosky 🛟🧪
Complex chart showing a peanut above the skin layer with S. Aureus bacteria. This triggers a chain of reaction in the skin and in the lymph nodes. When the baby eats the peanut, it triggers the tuft cells and SAP and this eventually causes mast cells to degranulate.
July 8, 2025 at 4:45 AM
foodallergyscience.org
We are thrilled to have Dr. Ivan de Araujo, FASI Principal Investigator and Director of the Max Planck Institute for Biological Cybernetics join us at our 2025 Symposium on September 12, 2025 at The Broad Institute of MIT and Harvard.

Register today: foodallergyscience.org/fasi-symposi...
June 28, 2025 at 2:47 AM
foodallergyscience.org
We are thrilled to have Dr. Christina Wierenga, Professor of Psychiatry University of California San Diego join us at our 2025 Symposium on September 12, 2025 at The Broad Institute of MIT and Harvard.

Register today: foodallergyscience.org/fasi-symposi...

#immunosky #allergysky #foodallergy
June 28, 2025 at 2:45 AM
foodallergyscience.org
FASI investigator Dr. Sarita Patil examined the structure of antibodies that bind peanut allergens & found a variety of antibodies that can bind peanut allergens!

www.science.org/doi/10.1126/...

#allergysky #pedsky #immunosky #medsky

Photo credit: Monica Fernández-Quintero/Johannes R. Loeffler
June 28, 2025 at 2:43 AM
foodallergyscience.org
Great Research spotlight! One of our FASI funded PIs @danmucida.bsky.social is one of the five papers! Stay tuned as we plan to share more about that work next month!
June 11, 2025 at 11:58 PM
Reposted by Food Allergy Science Initiative
natrevimmunol.nature.com
Not one, not two .... but FIVE recent papers highlighting a role for RORgt+ antigen-presenting cells in the gut in establishing tolerance to food antigens
#oraltolerance #immunosky #foodallergy
RORγt+ antigen-presenting cells mediate food tolerance - Nature Reviews Immunology
Five recent papers identify the RORγt+ antigen-presenting cells that induce food-antigen-specific regulatory T cells and establish food tolerance.
www.nature.com
May 29, 2025 at 3:46 PM
Reposted by Food Allergy Science Initiative
affinityborn.bsky.social
Our new Immunity paper is in print—and that an oil painting I made was chosen for the cover 😊

It visualizes “affinity birth,” the generative force of SHM creating new antibody specificities beyond V(D)J.

#Immunology #AffinityBirth #SciArt #Bcells #SHM
June 10, 2025 at 6:06 PM
Reposted by Food Allergy Science Initiative
maurogaya.bsky.social
Dr. Daniel Mucida from the The Rockefeller University 🇺🇸 will be presenting his work on "Immune-epithelial cell interactions during food allergy". Check his recent study on antigen-presenting cells and dietary allergens: pubmed.ncbi.nlm.nih.gov/39700315/

@danmucida.bsky.social

#EMBOBarrierTissues
May 21, 2025 at 11:43 AM
foodallergyscience.org
Great @science.org review on Neuroimmune--a lot of FASI PIs research is cited, and FASI is proud to have pioneered the field of neuroimmunology in Food Allergies. Follow us for the latest in food allergy research!

#immunosky #foodallergy #allergysky #micobiomesky
science.org Science Magazine @science.org · May 22
In a new #ScienceImmunology Review, researchers discuss how interactions between the nervous and immune systems could impact neurological disorders and allergy-related behaviors like food avoidance. scim.ag/4mpgzE5
The nervous system comprises the CNS and associated sensory nerves (blue) and the autonomic nervous system, which includes sympathetic and parasympathetic nerves (red) and the ENS (purple). The immune system is composed of cells that span the entire body. This includes the meningiocranial immune system, which comprises immune cells important for neural development, brain repair, and brain border protection. Repeated exposure to allergens at mucosal sites (for example, lung, skin, and gut) can trigger local type 2 immunity. Type 2 immune cells signal to neurons across the periphery and brain through cytokines, whereas neurons signal to immune cells via neurotransmitters and neuropeptides. This is not an exhaustive list of cellular players, given that other tissue resident cells (e.g., fibroblasts and glial cells) may also respond to these signals.
June 10, 2025 at 7:28 PM
foodallergyscience.org
New from FASI investigator Dr. Andrew Wang: T cells trained by the gut microbiome live in the brain and help keep it in balance—until the microbiome is disrupted.

This gut-brain-immune link may be key to food allergy tolerance. www.nature.com/articles/s41...

#Microbiomesky #allergysky #immunosky
June 10, 2025 at 7:19 PM
foodallergyscience.org
Three critical questions are at the core of our mission.

By delving into the science behind these questions, we are working to uncover new insights that can improve the lives of millions affected by food allergies.

#allergysky #immunosky #medsky
May 28, 2025 at 2:03 PM
Reposted by Food Allergy Science Initiative
foodallergyscience.org
Why do some allergic reactions turn deadly?

Research from FASI PI Dr. Stephanie Eisenbarth identifies a rare immune cell—TFH13—that triggers high-affinity IgE production, a key driver of anaphylaxis.

pubmed.ncbi.nlm.nih.gov/31371561

#immunosky #allergysky #pedsky #medsky #foodallergies
May 16, 2025 at 2:15 PM