Fanny Le Blanc
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fannyleblanc.bsky.social
Fanny Le Blanc
@fannyleblanc.bsky.social
PhD candidate in the Engel lab, Biozentrum, using cryo-ET to study photosynthesis in green algae 🌱 #TeamTomo
Reposted by Fanny Le Blanc
We’re back with the next DinoSphere Online Seminar!

Join us on Nov 4th, we're hosting:

Edmée Royen (ULiège) - Symbiodinium

Nicolas dos Santos Pacheco (Cambridge) - Perkinsids

📅 Tue, Nov 4 - 4 PM CET/3 PM GMT

💻 Zoom link: sites.google.com/view/dinosphere

Please spread the word!
#protistonsky
October 28, 2025 at 3:29 PM
Reposted by Fanny Le Blanc
That’s a wrap of the 2nd edition of our one of a kind structural biology block course at the @biozentrum.unibas.ch! In just 6 short weeks students designed protein oligomers; rotated in cryo-ET, cryo-EM SPA, AFM, and NMR labs; and expressed, purified, and structurally characterized their designs
October 25, 2025 at 12:57 PM
Reposted by Fanny Le Blanc
How can we see the cells that make up a living organism? Membrane-localising tags can drive fluorescent proteins to the cell's outer membrane, making their outlines visible. But the tags don't work well in all organisms. How do you find one for your species of interest? 🧵

Check our latest preprint
A toolkit for testing membrane-localising tags across species
Transgenic markers and tools have revolutionised how we study cells and developing organisms. Some of the elements needed to construct those tools are universally applicable (e.g. fluorescent proteins...
www.biorxiv.org
October 23, 2025 at 8:16 AM
Reposted by Fanny Le Blanc
Last Friday (17th), we had an amazing first Young Swiss Tomo meeting in Bern, organized with Elda Bauda, Zanetta Kechagia, and @leonieanton.bsky.social!
Over 70 people from 🇨🇭 gathered to talk about cryo-electron tomography 🔬.
Huge thanks to the DCI for making the event possible! See you next year! 👋
October 19, 2025 at 9:16 AM
Reposted by Fanny Le Blanc
Pretty excited to share our new preprint!
Non-photosynthetic Plastid Replacement by a Primary Plastid in the Making
www.biorxiv.org/content/10.1...
October 10, 2025 at 3:34 AM
Reposted by Fanny Le Blanc
Nudibranchs as pictured by a Japanese illustrator named Kumataro Ito, artist for the USS Albatross’ Philippine Expedition, 1907–10. More of his stunning images here: publicdomainreview.org/collection/k...
September 30, 2025 at 4:47 PM
Reposted by Fanny Le Blanc
🌱 Using ‘compelling’ methods, including #CryoET, researchers mapped spinach thylakoid membranes at single-molecule precision, revealing how photosynthetic complexes are organised and settling long-standing debates on chloroplast architecture.
buff.ly/j3TSIkn
September 20, 2025 at 1:59 PM
Reposted by Fanny Le Blanc
New paper is out! We have studied the cute tiny Discocelia plataet sp. n. to obtain the first molecular data of the order Discocelida and clarify its cell structure. All this for a better understanding of the evolution of Cercozoa.

onlinelibrary.wiley.com/doi/epdf/10....
August 26, 2025 at 4:54 PM
Reposted by Fanny Le Blanc
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
August 21, 2025 at 5:19 AM
Reposted by Fanny Le Blanc

Our work, co-led by @alfredo0712.bsky.social and @nlue8.bsky.social is out in @natsmb.nature.com Shout out to coauthors P.Grob, B. Kaeser, J.Fang, and S. Kassube for their contributions and thanks to the reviewers for the suggestions that led to the final work.
www.nature.com/articles/s41...
Structural insights into transcriptional regulation by the helicase RECQL5 - Nature Structural & Molecular Biology
Florez Ariza and Lue et al. use cryo-electron microscopy to investigate how the RECQL5 helicase regulates transcription. Their structural findings suggest that RECQL5 can modulate RNA polymerase II’s ...
www.nature.com
July 7, 2025 at 10:35 AM
Reposted by Fanny Le Blanc
We’re kicking off the DinoSphere Online Seminar Series! Join us for our first session with Karel Mockaer (Heidelberg) & Yong Heng Phua (OIST)

📅 1 July 9AM CEST
🔗 tinyurl.com/4mjaverj

Spread the word!
@protistwtmostest.bsky.social @ehehenberger.bsky.social @chandnibhickta.bsky.social&Norico Yamada
June 4, 2025 at 4:34 AM
Reposted by Fanny Le Blanc
The final version of our work on the in-cell architecture of the mitochondrial respiratory chain is now online in @science.org 🎉
You can find the full story here www.science.org/doi/10.1126/...
@verenaresch.bsky.social did a wonderful job on the cover and animation, she really brought it to life 👩‍🎨
In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion.

Learn more in this week's issue: scim.ag/3FA3Ygq
March 20, 2025 at 6:20 PM
Reposted by Fanny Le Blanc
We (@cellarchlab.com peeps, @manondemulder.bsky.social @phaips.vd.st @fannyleblanc.bsky.social @computingcaitie.bsky.social and Ricardo) had a blast at the EMBO in situ meeting in Heidelberg! Meeting old friends and making new ones! Lots of cool science and new ideas to try 👨🏻‍🔬🔬
February 6, 2025 at 7:27 PM
Reposted by Fanny Le Blanc
This one was delayed for a while… apologies to the musicians. Collab with Matt, Will and Lorna (over on Twitter). And a great dev effort from Lorenz @lorenzlamm.bsky.social. Ofc @cellarchlab.com team. Comment if you want to help. #teamthylakoid

www.biorxiv.org/content/10.1...
Molecular architecture of thylakoid membranes within intact spinach chloroplasts
Thylakoid membranes coordinate the light reactions of photosynthesis across multiple scales, coupling the architecture of an elaborate membrane network to the spatial organization of individual protei...
www.biorxiv.org
November 27, 2024 at 6:55 AM
Feeling super grateful to have participated in the #EMBOStructBio workshop in Hamburg last week! The talks and tutorials were top-notch and it was great fun connecting with everyone :)
November 25, 2024 at 1:34 PM
Reposted by Fanny Le Blanc
November 22, 2024 at 1:06 PM
Reposted by Fanny Le Blanc
Say hi 👋 to @fannyleblanc.bsky.social! Five CellAchLab members on bsky💙 so far, including @computingcaitie.bsky.social @sofie-dot-rec.bsky.social @florentwaltz.bsky.social @wojwie.bsky.social. Science party!👩‍🔬🕺

#TeamTomo #CryoEM🧪🔬🧶🧬🌾
November 21, 2024 at 7:50 AM