Enrique Gabandé Rodríguez
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enriquegab.bsky.social
Enrique Gabandé Rodríguez
@enriquegab.bsky.social
30 followers 70 following 2 posts
Senior postdoctoral researcher at María Mittelbrunn's lab., Centro de Biología Molecular Severo Ochoa (CBMSO) @cbm-csic-uam.bsky.social.

https://www.scopus.com/authid/detail.uri?authorId=56019409600
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Reposted by Enrique Gabandé Rodríguez
cbm-csic-uam.bsky.social
📢¡Oferta de trabajo en el CBM!
El grupo de César Cobaleda busca postdoc para estudiar cómo se origina la leucemia infantil (B-ALL).
💡 Proyecto “la Caixa” Research Health 2025
🧬 Modelos murinos, epigenética, célula única
📅 Deadline: 5 dic 2025
www.cbm.uam.es/index.php/jo...
@cjchcm.bsky.social
Molecular Mechanisms of Childhood Leukemia Development - Centro de Biología Molecular Severo Ochoa
Job Description We are seeking a highly motivated postdoctoral researcher to join our laboratory to study the early steps of development of childhood B-cell Acute Lymphoblastic Leukemia (B-ALL). The p...
www.cbm.uam.es
November 12, 2025 at 7:44 PM
Reposted by Enrique Gabandé Rodríguez
analechugavieco.bsky.social
🌟 Barcelona scientists, don’t miss out!
Tomorrow we host Dr. María Mittelbrunn for our plenary seminar. It is going to be a great one! @irbbarcelona.org

mmittelbrunnlab.cbm.uam.es
October 23, 2025 at 8:02 PM
Reposted by Enrique Gabandé Rodríguez
manuel-collado.bsky.social
Sad to hear about the passing of John Gurdon, a titan and pioneer of developmental biology and much more. Winner of the Nobel Prize in Medicine or Physiology, shared with Shinya Yamanaka, who actually was inspired by his work
www.cam.ac.uk/research/new...
Nobel Laureate Professor Sir John Gurdon dies aged 92
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the Gurdon Institute.
www.cam.ac.uk
October 7, 2025 at 4:41 PM
Reposted by Enrique Gabandé Rodríguez
labwaggoner.bsky.social
Review @sciimmunology.bsky.social @platten-lab.bsky.social
@dkfz.bsky.social
The immunology of brain tumors
www.science.org/doi/10.1126/...
October 3, 2025 at 7:32 PM
Reposted by Enrique Gabandé Rodríguez
natcomms.nature.com
Diabetes-induced senescence of endothelial cells shown to promote pancreatic cancer progression doi.org/10.1038/s414...
October 2, 2025 at 4:35 PM
Reposted by Enrique Gabandé Rodríguez
alejofraticelli.bsky.social
O M G
johanduchene.bsky.social Johan Duchêne @johanduchene.bsky.social · Sep 29
PARKIN labels damaged mitochondria for recycling
No PARKIN → no cleanup → neurodegeneration
Mutations in PARK2 are common in Parkinson’s disease

Accurate detection of PARKIN is crucial

Problem:
The most used antibodies are not selective
In contrast, some very specific antibodies are not used
Parkin antibody screening by immunoblot. Lysates of SH-SY5Y (WT and PRKN KO) were prepared and 50 μg of protein were processed for immunoblot with the indicated Parkin antibodies. The Ponceau stained transfers of each blot are shown. Antibody dilution used: 702785 at 1/200; 711820 at 1/200; 39-0900 at 1/500; ab77924 at 1/200; ab15954 at 1/500; 14060-1-AP at 1/1000; MAB1438 at 1/250; MAB14381 at 1/500; GTX39745 at 1/1000; GTX65811 at 1/1000. Predicted band size: 52 kDa. Which antibody should you choose then?
September 29, 2025 at 7:23 PM
Reposted by Enrique Gabandé Rodríguez
cbm-csic-uam.bsky.social
🎥🔬 50 años descodificando la vida.
Descubre en este video cómo el CBM ha marcado la biomedicina en España y el mundo, formando talento y generando ciencia de impacto.
#CincuentenarioCBM #DecodingLife youtu.be/7bzJOIW5kyM
Cincuentenario del Centro Biología Molecular Severo Ochoa - Decoding life
YouTube video by Centro de Biología Molecular Severo Ochoa
youtu.be
September 29, 2025 at 1:02 PM
Reposted by Enrique Gabandé Rodríguez
nature.com
Nature research paper: Rewiring of cortical glucose metabolism fuels human brain cancer growth

go.nature.com/4lZtawb
Rewiring of cortical glucose metabolism fuels human brain cancer growth - Nature
The cortex fuels essential physiological processes with glucose-derived carbon, while gliomas fuel their aggressiveness by rerouting glucose carbon pathways and scavenging alternative carbon sources such as environmental amino acids, providing a potential therapeutic target.
go.nature.com
September 4, 2025 at 5:08 PM
Reposted by Enrique Gabandé Rodríguez
javierdn.bsky.social
José Antonio Marina (86 años), catedrático de filosofía: “Un amigo de verdad es el que te hace mejor. Y si no te hace mejor, no es un amigo, es otra cosa”

www.cuerpomente.com/psicologia/j...
José Antonio Marina (86 años), catedrático de filosofía: “Un amigo de verdad es el que te hace mejor. Y si no te hace mejor, no es un amigo, es otra cosa”
¿Qué significa tener un buen amigo? ¿Cuál es el verdadero valor de la amistad? ¿Y cómo deberíamos cultivar nuestras relaciones de amistad para hacerlas verdaderamente significativas? El filósofo José ...
www.cuerpomente.com
August 30, 2025 at 8:02 PM
Reposted by Enrique Gabandé Rodríguez
labwaggoner.bsky.social
Hematopoietic loss of Y chromosome leads to immune inhibitory receptor up-regulation, impairing senescent cell clearance
www.science.org/doi/10.1126/...
August 6, 2025 at 7:09 PM
Reposted by Enrique Gabandé Rodríguez
csic.es
🔬Un estudio del CSIC demuestra que el deterioro asociado a la edad de los linfocitos T CD4 debilita la barrera intestinal y favorece la inflamación crónica y el envejecimiento celular

💉 El trabajo también presenta una posible terapia

➡️ https://tinyurl.com/97ssrv74
August 4, 2025 at 8:02 AM
Reposted by Enrique Gabandé Rodríguez
jorgeoller.bsky.social
Our paper is here online! EHJ . Excessive glycosylation drives thoracic aortic aneurysm formation through integrated stress response url: academic.oup.com/eurheartj/ar...
Excessive glycosylation drives thoracic aortic aneurysm formation through integrated stress response
AbstractBackground and Aims. Thoracic aortic aneurysms and dissections (TAADs) are depicted by aortic medial degeneration characterized by glycan-rich matr
academic.oup.com
July 30, 2025 at 8:19 AM
enriquegab.bsky.social
Manu got the cover on our lab latest publication. Congratulations @mmgomezheras.bsky.social . So much deserved!
August 2, 2025 at 1:18 PM
Reposted by Enrique Gabandé Rodríguez
ecarrascouam.bsky.social
Especially excited to share this research led by @mmgomezheras.bsky.social ! 🤩 We show that a competent CD4+ T cell compartment is key to fostering host-microbiota mutualism and maintaining intestinal barrier integrity, becoming crucial to prevent inflammaging www.science.org/doi/10.1126/...
August 1, 2025 at 10:56 PM
Reposted by Enrique Gabandé Rodríguez
immunoeditor.bsky.social
The August issue of #Science #Immunology is out! This week: T peripheral helper cells expressing IGFL2 contribute to rheumatoid #arthritis; vagal TRPV1+ sensory #neurons protect against #influenza virus infection; & transfer of #Tregs alleviates #inflammaging in mice!

wwwscience.org/toc/sciimmun...
August 1, 2025 at 8:21 PM
Reposted by Enrique Gabandé Rodríguez
immunoeditor.bsky.social
This week's cover, illustrated by the amazing Ashley Mastin, highlights work by @mmgomezheras.bsky.social & al.!
CD4 T cell therapy counteracts inflammaging and senescence by preserving gut barrier integrity
Treg cells safeguard the intestinal barrier to prevent inflammaging and senescence in a mouse model of premature aging.
www.science.org
August 1, 2025 at 8:29 PM
Reposted by Enrique Gabandé Rodríguez
adrover.bsky.social
I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...
Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature
Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.
www.nature.com
July 17, 2025 at 11:28 AM
Reposted by Enrique Gabandé Rodríguez
cbm-csic-uam.bsky.social
Hoy nos ha visitado Nina Cabezas-Wallscheid (ETH Zurich) para dar un seminario organizado por nuestro comité de Predocs & Postdocs. Nos ha hablado de cómo los componentes de la dieta influyen en la regulación metabólica y epigenética de las células madre hematopoyéticas en estado latente.
May 9, 2025 at 1:12 PM
Reposted by Enrique Gabandé Rodríguez
cbm-csic-uam.bsky.social
Investigadores del Hospital 12 de Octubre y del CBM, junto a otros colaboradores, descubren porqué aumenta el riesgo de padecer un grupo de enfermedades hematológicas crónicas como las leucemias. www.cbm.uam.es/index.php/20...
Descubren porqué aumenta el riesgo de padecer un grupo de enfermedades hematológicas crónicas. - Centro de Biología Molecular Severo Ochoa
Una investigación liderada por el Hospital público 12 de Octubre de la Comunidad de Madrid en colaboración con el Centro de Biología Molecular Severo Ochoa (CBM-CSIC-UAM), ha descubierto el motivo […]
www.cbm.uam.es
May 7, 2025 at 12:02 PM
Reposted by Enrique Gabandé Rodríguez
ecarrascouam.bsky.social
Check out the most recent publication of our team at @cbm-csic-uam.bsky.social. Thanks to #GonzaloSoto-Heredero @enriquegab.bsky.social and all the team! www.nature.com/articles/s43...
KLRG1 identifies regulatory T cells with mitochondrial alterations that accumulate with aging - Nature Aging
T cells undergo age-related changes that impair their organismal functions. Here Soto-Heredero et al. show that regulatory T cells characterized by the expression of KLRG1 accumulate with age in both ...
www.nature.com
May 3, 2025 at 6:37 AM
Reposted by Enrique Gabandé Rodríguez
cbm-csic-uam.bsky.social
Investigadores del grupo de Felipe X. Pimentel han identificado un mecanismo que podría potenciar la inmunoterapia frente al cáncer. Han hallado conexiones inesperadas entre la muerte celular programada y la autofagia o ‘autocanibalismo’ celular.
www.cbm.uam.es/index.php/20...
@csic.es @uam.es
Identificado un mecanismo que podría potenciar la inmunoterapia frente al cáncer - Centro de Biología Molecular Severo Ochoa
Un equipo del Centro de Biología Molecular Severo Ochoa (CBM-CSIC-UAM) ha hallado un mecanismo celular que podría potenciar la respuesta inmune del organismo frente al cáncer. La investigación, que ap...
www.cbm.uam.es
April 25, 2025 at 11:33 AM
Reposted by Enrique Gabandé Rodríguez
mariangelesmoro.bsky.social
Amazing talk on “New insights into the anatomy of ‘brainwashing’” by Jonathan Kipnis @jonykipnis.bsky.social from @washumedicinebsky.social at #CNIC today 🙇🏼‍♀️🙇🏼‍♀️👏🏻👏🏻👏🏻👏🏻
April 21, 2025 at 1:34 PM
Reposted by Enrique Gabandé Rodríguez
moorejh.bsky.social
The scientific community must take a strong and active stand against vaccine revisionism — the false narrative that there is insufficient evidence to support the safety and efficacy of vaccines www.nature.com/articles/s41... #vaccines #immunology #virology
Combating vaccine revisionism - Nature Medicine
The scientific community must take a strong and active stand against vaccine revisionism — the false narrative that there is insufficient evidence to support the safety and efficacy of vaccines.
www.nature.com
April 20, 2025 at 4:03 PM
Reposted by Enrique Gabandé Rodríguez
labwaggoner.bsky.social
NKG2D-mediated cytotoxicity of CD4 cytotoxic T cells in multiple myeloma @bloodjournal.bsky.social
doi.org/10.1182/bloo...
NKG2D-mediated cytotoxicity of CD4 cytotoxic T cells in multiple myeloma
Key Points. CD4 CTLs are significantly increased and clonally expanded in the bone marrow of patients with multiple myeloma.CD4 CTLs directly kill myeloma
doi.org
March 28, 2025 at 7:30 PM