Elisabetta Mereu
@elimereu.bsky.social
Group leader at the Josep Carreras Leukemia Research Institute. Passionate of single-cell genomics and ML! Advancing personalized therapies for cancer and beyond. #singlecellgenomics #Immunotherapy
Pinned
Elisabetta Mereu
@elimereu.bsky.social
· Mar 10
📖 Too tired to read? No problem! 🎧 Listen to the #NotebookLM podcast at the end of the post here: www.mereulab.org/post/do-we-r...
Reposted by Elisabetta Mereu
The Berlin crew Ashley Sanders @simonhaas.bsky.social @leifludwig.bsky.social @stefaniegrosswendt.bsky.social is passing the torch to our co-organizers and partners in crime @elimereu.bsky.social @larsplus.bsky.social @alejofraticelli.bsky.social for ISCO 2026 in Barcelona
www.isco-conference.eu
www.isco-conference.eu
May 13, 2025 at 9:16 PM
The Berlin crew Ashley Sanders @simonhaas.bsky.social @leifludwig.bsky.social @stefaniegrosswendt.bsky.social is passing the torch to our co-organizers and partners in crime @elimereu.bsky.social @larsplus.bsky.social @alejofraticelli.bsky.social for ISCO 2026 in Barcelona
www.isco-conference.eu
www.isco-conference.eu
Reposted by Elisabetta Mereu
The Innovations in Single Cell Omics conference in Berlin was amazing! Great talks and we even had a Night Science workshop! 🙏 @stefaniegrosswendt.bsky.social, Ashley Sanders, @simonhaas.bsky.social, @leifludwig.bsky.social, @elimereu.bsky.social, @larsplus.bsky.social & @alejofraticelli.bsky.social
Just wrapped up 2 inspiring days at ISCO – Innovations in Single Cell Omics! A great community came together to share science and fun. A big THANK YOU to all our fantastic speakers and interactive participants
May 13, 2025 at 9:52 PM
The Innovations in Single Cell Omics conference in Berlin was amazing! Great talks and we even had a Night Science workshop! 🙏 @stefaniegrosswendt.bsky.social, Ashley Sanders, @simonhaas.bsky.social, @leifludwig.bsky.social, @elimereu.bsky.social, @larsplus.bsky.social & @alejofraticelli.bsky.social
Reposted by Elisabetta Mereu
Meet Alessia Buratin 👩🔬
She focuses on Single Cell Multi Omics and Deep Learning Approach to reverse immunosuppression in Multiple Myeloma, under the supervision of Dra @elimereu.bsky.social at @carrerasijc.bsky.social.
Read about Alessia and her project: carrerasleaders.eu/postdoctoral...
She focuses on Single Cell Multi Omics and Deep Learning Approach to reverse immunosuppression in Multiple Myeloma, under the supervision of Dra @elimereu.bsky.social at @carrerasijc.bsky.social.
Read about Alessia and her project: carrerasleaders.eu/postdoctoral...
May 8, 2025 at 2:02 PM
Meet Alessia Buratin 👩🔬
She focuses on Single Cell Multi Omics and Deep Learning Approach to reverse immunosuppression in Multiple Myeloma, under the supervision of Dra @elimereu.bsky.social at @carrerasijc.bsky.social.
Read about Alessia and her project: carrerasleaders.eu/postdoctoral...
She focuses on Single Cell Multi Omics and Deep Learning Approach to reverse immunosuppression in Multiple Myeloma, under the supervision of Dra @elimereu.bsky.social at @carrerasijc.bsky.social.
Read about Alessia and her project: carrerasleaders.eu/postdoctoral...
Reposted by Elisabetta Mereu
We're pleased to announce that Dr Ari Melnick has been appointed new Director of the Josep Carreras Institute.
Dr Melnick will lead IJC in our mission to advance #research in #leukaemia and other malignant blood diseases.
Read the full release here: www.carrerasresearch.org/en/news/dr-a...
Dr Melnick will lead IJC in our mission to advance #research in #leukaemia and other malignant blood diseases.
Read the full release here: www.carrerasresearch.org/en/news/dr-a...
April 22, 2025 at 2:05 PM
We're pleased to announce that Dr Ari Melnick has been appointed new Director of the Josep Carreras Institute.
Dr Melnick will lead IJC in our mission to advance #research in #leukaemia and other malignant blood diseases.
Read the full release here: www.carrerasresearch.org/en/news/dr-a...
Dr Melnick will lead IJC in our mission to advance #research in #leukaemia and other malignant blood diseases.
Read the full release here: www.carrerasresearch.org/en/news/dr-a...
Reposted by Elisabetta Mereu
Proud of our new perspective describing the role of mathematical biology for immunotherapy www.nature.com/articles/s41... @natbiotech.nature.com
Virtual cells for predictive immunotherapy - Nature Biotechnology
Synergizing advances in artificial intelligence with mathematical modeling will improve our ability to computationally predict immunotherapy outcomes.
www.nature.com
April 15, 2025 at 2:17 AM
Proud of our new perspective describing the role of mathematical biology for immunotherapy www.nature.com/articles/s41... @natbiotech.nature.com
Reposted by Elisabetta Mereu
Epigenetic enhancement of adoptive T cell immunotherapy www.cell.com/cancer-cell...
March 30, 2025 at 2:15 PM
Epigenetic enhancement of adoptive T cell immunotherapy www.cell.com/cancer-cell...
Reposted by Elisabetta Mereu
On my way to #Ascona in Switzerland) for this exciting congress, where we will discuss about modern benchmarking strategies to advance molecular biology!! Happy also to present our findings on the latest systematic evaluation of #singlecell multimodal data integrations in complex tissues. 🧬🔬👩🏻💻👩🏻🔬
Quick update. We have a pretty exciting lineup of topics/speakers in and around benchmarking that will be presented in Ascona at the end of the month:
sites.google.com/view/ascona2...
There are few registration slots left, so if you are interested to join us, get in touch.
sites.google.com/view/ascona2...
There are few registration slots left, so if you are interested to join us, get in touch.
March 23, 2025 at 3:14 PM
On my way to #Ascona in Switzerland) for this exciting congress, where we will discuss about modern benchmarking strategies to advance molecular biology!! Happy also to present our findings on the latest systematic evaluation of #singlecell multimodal data integrations in complex tissues. 🧬🔬👩🏻💻👩🏻🔬
Reposted by Elisabetta Mereu
🔬 Curious about the impact of #singlecell multimodal data on cell-type discovery? Check out our latest study: www.mereulab.org/post/do-we-r... .
📖 Too tired to read? No problem! 🎧 Listen to the NotebookLM #podcast included at the end of the post instead!
📖 Too tired to read? No problem! 🎧 Listen to the NotebookLM #podcast included at the end of the post instead!
Do we really know the impact of multiple single-cell data types?
We often assume that single-cell sequencing gives us a complete picture of cellular diversity, but actually, we already saw in previous publications, like here and here, that one protocol is not reall...
www.mereulab.org
March 10, 2025 at 5:55 PM
🔬 Curious about the impact of #singlecell multimodal data on cell-type discovery? Check out our latest study: www.mereulab.org/post/do-we-r... .
📖 Too tired to read? No problem! 🎧 Listen to the NotebookLM #podcast included at the end of the post instead!
📖 Too tired to read? No problem! 🎧 Listen to the NotebookLM #podcast included at the end of the post instead!
Reposted by Elisabetta Mereu
Join us at "Innovations in Single Cell Omics" in Berlin 5.12-13 (+ night science workshop!)
www.isco-conference.eu
Organizers:
@stefaniegrosswendt.bsky.social, @simonhaas.bsky.social
@leifludwig.bsky.social, Ashley Sanders, @larsplus.bsky.social, @elimereu.bsky.social, @alejofraticelli.bsky.social
www.isco-conference.eu
Organizers:
@stefaniegrosswendt.bsky.social, @simonhaas.bsky.social
@leifludwig.bsky.social, Ashley Sanders, @larsplus.bsky.social, @elimereu.bsky.social, @alejofraticelli.bsky.social
March 13, 2025 at 2:08 PM
Join us at "Innovations in Single Cell Omics" in Berlin 5.12-13 (+ night science workshop!)
www.isco-conference.eu
Organizers:
@stefaniegrosswendt.bsky.social, @simonhaas.bsky.social
@leifludwig.bsky.social, Ashley Sanders, @larsplus.bsky.social, @elimereu.bsky.social, @alejofraticelli.bsky.social
www.isco-conference.eu
Organizers:
@stefaniegrosswendt.bsky.social, @simonhaas.bsky.social
@leifludwig.bsky.social, Ashley Sanders, @larsplus.bsky.social, @elimereu.bsky.social, @alejofraticelli.bsky.social
Reposted by Elisabetta Mereu
🚀 Join the #ISCO2025 community at @mdc-berlin.bsky.social on May 12-13! 🚀
Don't miss this incredible opportunity to connect with top #singlecell & #spatial omics experts and participate in a special Workshop led by @itaiyanai.bsky.social.
⏳Abstract submissions: March 21)
www.isco-conference.eu
Don't miss this incredible opportunity to connect with top #singlecell & #spatial omics experts and participate in a special Workshop led by @itaiyanai.bsky.social.
⏳Abstract submissions: March 21)
www.isco-conference.eu
ISCO - ISCO
www.isco-conference.eu
March 12, 2025 at 3:36 PM
🚀 Join the #ISCO2025 community at @mdc-berlin.bsky.social on May 12-13! 🚀
Don't miss this incredible opportunity to connect with top #singlecell & #spatial omics experts and participate in a special Workshop led by @itaiyanai.bsky.social.
⏳Abstract submissions: March 21)
www.isco-conference.eu
Don't miss this incredible opportunity to connect with top #singlecell & #spatial omics experts and participate in a special Workshop led by @itaiyanai.bsky.social.
⏳Abstract submissions: March 21)
www.isco-conference.eu
🚀 Join the #ISCO2025 community at @mdc-berlin.bsky.social on May 12-13! 🚀
Don't miss this incredible opportunity to connect with top #singlecell & #spatial omics experts and participate in a special Workshop led by @itaiyanai.bsky.social.
⏳Abstract submissions: March 21)
www.isco-conference.eu
Don't miss this incredible opportunity to connect with top #singlecell & #spatial omics experts and participate in a special Workshop led by @itaiyanai.bsky.social.
⏳Abstract submissions: March 21)
www.isco-conference.eu
ISCO - ISCO
www.isco-conference.eu
March 12, 2025 at 3:36 PM
🚀 Join the #ISCO2025 community at @mdc-berlin.bsky.social on May 12-13! 🚀
Don't miss this incredible opportunity to connect with top #singlecell & #spatial omics experts and participate in a special Workshop led by @itaiyanai.bsky.social.
⏳Abstract submissions: March 21)
www.isco-conference.eu
Don't miss this incredible opportunity to connect with top #singlecell & #spatial omics experts and participate in a special Workshop led by @itaiyanai.bsky.social.
⏳Abstract submissions: March 21)
www.isco-conference.eu
📖 Too tired to read? No problem! 🎧 Listen to the #NotebookLM podcast at the end of the post here: www.mereulab.org/post/do-we-r...
March 10, 2025 at 6:03 PM
📖 Too tired to read? No problem! 🎧 Listen to the #NotebookLM podcast at the end of the post here: www.mereulab.org/post/do-we-r...
🔬 Curious about the impact of #singlecell multimodal data on cell-type discovery? Check out our latest study: www.mereulab.org/post/do-we-r... .
📖 Too tired to read? No problem! 🎧 Listen to the NotebookLM #podcast included at the end of the post instead!
📖 Too tired to read? No problem! 🎧 Listen to the NotebookLM #podcast included at the end of the post instead!
Do we really know the impact of multiple single-cell data types?
We often assume that single-cell sequencing gives us a complete picture of cellular diversity, but actually, we already saw in previous publications, like here and here, that one protocol is not reall...
www.mereulab.org
March 10, 2025 at 5:55 PM
🔬 Curious about the impact of #singlecell multimodal data on cell-type discovery? Check out our latest study: www.mereulab.org/post/do-we-r... .
📖 Too tired to read? No problem! 🎧 Listen to the NotebookLM #podcast included at the end of the post instead!
📖 Too tired to read? No problem! 🎧 Listen to the NotebookLM #podcast included at the end of the post instead!
Reposted by Elisabetta Mereu
Ever wondered why we do all these #Omics?
Here is your answer: biorxiv.org/content/10.1... 📜
Multi-Omics integration of a Human Cell Atlas
@humancellatlas.org of the Kidney, coordinated by the #HCA Standards and Technology Working Group and co-led by
@elimereu.bsky.social.
Here is your answer: biorxiv.org/content/10.1... 📜
Multi-Omics integration of a Human Cell Atlas
@humancellatlas.org of the Kidney, coordinated by the #HCA Standards and Technology Working Group and co-led by
@elimereu.bsky.social.
Systematic evaluation of single-cell multimodal data integration for comprehensive human reference atlas.
The integration of multimodal single-cell data enables comprehensive organ reference atlases, yet its impact remains largely unexplored, particularly in complex tissues. We generated a benchmarking da...
biorxiv.org
March 7, 2025 at 7:01 PM
Ever wondered why we do all these #Omics?
Here is your answer: biorxiv.org/content/10.1... 📜
Multi-Omics integration of a Human Cell Atlas
@humancellatlas.org of the Kidney, coordinated by the #HCA Standards and Technology Working Group and co-led by
@elimereu.bsky.social.
Here is your answer: biorxiv.org/content/10.1... 📜
Multi-Omics integration of a Human Cell Atlas
@humancellatlas.org of the Kidney, coordinated by the #HCA Standards and Technology Working Group and co-led by
@elimereu.bsky.social.
🚀 New Preprint Alert! 🚀 With the Standards and Technology Working Group of the @humancellatlas.org, we present a new preprint guiding multimodal #singlecell data integration and human organ atlas generation! 📄
Read the preprint: www.biorxiv.org/content/10.1...
Read the preprint: www.biorxiv.org/content/10.1...
Systematic evaluation of single-cell multimodal data integration for comprehensive human reference atlas.
The integration of multimodal single-cell data enables comprehensive organ reference atlases, yet its impact remains largely unexplored, particularly in complex tissues. We generated a benchmarking da...
www.biorxiv.org
March 7, 2025 at 9:54 AM
🚀 New Preprint Alert! 🚀 With the Standards and Technology Working Group of the @humancellatlas.org, we present a new preprint guiding multimodal #singlecell data integration and human organ atlas generation! 📄
Read the preprint: www.biorxiv.org/content/10.1...
Read the preprint: www.biorxiv.org/content/10.1...
Reposted by Elisabetta Mereu
Today, 2 postdoctoral researchers from #CarrerasLeaders have led our Young Researcher Seminars🙌
🧑🔬👩🔬 Gerard Martínez (@scuartero.bsky.social lab) has presented his work on myeloid leukemia of Down syndrome and Alessia Buratin ( @elimereu.bsky.social lab) on machine learning to enhance CAR-T therapies
🧑🔬👩🔬 Gerard Martínez (@scuartero.bsky.social lab) has presented his work on myeloid leukemia of Down syndrome and Alessia Buratin ( @elimereu.bsky.social lab) on machine learning to enhance CAR-T therapies
February 25, 2025 at 3:50 PM
Today, 2 postdoctoral researchers from #CarrerasLeaders have led our Young Researcher Seminars🙌
🧑🔬👩🔬 Gerard Martínez (@scuartero.bsky.social lab) has presented his work on myeloid leukemia of Down syndrome and Alessia Buratin ( @elimereu.bsky.social lab) on machine learning to enhance CAR-T therapies
🧑🔬👩🔬 Gerard Martínez (@scuartero.bsky.social lab) has presented his work on myeloid leukemia of Down syndrome and Alessia Buratin ( @elimereu.bsky.social lab) on machine learning to enhance CAR-T therapies
Reposted by Elisabetta Mereu
ResolVI - addressing noise and bias in spatial transcriptomics www.biorxiv.org/content/10....
January 27, 2025 at 2:45 PM
ResolVI - addressing noise and bias in spatial transcriptomics www.biorxiv.org/content/10....
Reposted by Elisabetta Mereu
🚨 New paper alert 🚨 Our Human Microglia Atlas (HuMicA) characterizes #microglia subpopulations across 6 distinct #neurologic diseases. www.nature.com/articles/s41...
The Human Microglia Atlas (HuMicA) unravels changes in disease-associated microglia subsets across neurodegenerative conditions - Nature Communications
The Human Microglia Atlas includes 91,716 brain immune cells covering six neurologic pathologies. It characterizes the signatures of nine populations and describes the expansion of GPNMB-high microgli...
www.nature.com
January 16, 2025 at 5:45 PM
🚨 New paper alert 🚨 Our Human Microglia Atlas (HuMicA) characterizes #microglia subpopulations across 6 distinct #neurologic diseases. www.nature.com/articles/s41...
Great work on characterizing human microglia in 6 😱 neurological disorders! In collaboration with my next door colleagues at @eballestar.bsky.social’s lab!!
🚨 New paper alert 🚨 Our Human Microglia Atlas (HuMicA) characterizes #microglia subpopulations across 6 distinct #neurologic diseases. www.nature.com/articles/s41...
The Human Microglia Atlas (HuMicA) unravels changes in disease-associated microglia subsets across neurodegenerative conditions - Nature Communications
The Human Microglia Atlas includes 91,716 brain immune cells covering six neurologic pathologies. It characterizes the signatures of nine populations and describes the expansion of GPNMB-high microgli...
www.nature.com
January 17, 2025 at 7:19 AM
Great work on characterizing human microglia in 6 😱 neurological disorders! In collaboration with my next door colleagues at @eballestar.bsky.social’s lab!!
Reposted by Elisabetta Mereu
Made a #short about my internal conflicts on academic publishing #AcademicSky #PhDlife
"Stop asking me where I want to publish our paper. I don't care...I just want people to read it. And maybe learn from it. Even build on it. Ok?"
Is this #hopecore or #hopelesscore
youtube.com/shorts/GV7NJ...
"Stop asking me where I want to publish our paper. I don't care...I just want people to read it. And maybe learn from it. Even build on it. Ok?"
Is this #hopecore or #hopelesscore
youtube.com/shorts/GV7NJ...
internal conflicts on academic publishing #shorts #hopelesscore #hopecore #phdlife
YouTube video by Prof. Jean Fan
youtube.com
January 8, 2025 at 6:47 PM
Made a #short about my internal conflicts on academic publishing #AcademicSky #PhDlife
"Stop asking me where I want to publish our paper. I don't care...I just want people to read it. And maybe learn from it. Even build on it. Ok?"
Is this #hopecore or #hopelesscore
youtube.com/shorts/GV7NJ...
"Stop asking me where I want to publish our paper. I don't care...I just want people to read it. And maybe learn from it. Even build on it. Ok?"
Is this #hopecore or #hopelesscore
youtube.com/shorts/GV7NJ...
Reposted by Elisabetta Mereu
Researchers from the Crick have found that over 40% of variation in the way kidney cancer behaves is due to non-genetic factors.
The findings were led by Angel Fernandez Sanroman with senior author Samra Turajlic
www.crick.ac.uk/news-and-rep...
The findings were led by Angel Fernandez Sanroman with senior author Samra Turajlic
www.crick.ac.uk/news-and-rep...
Over 40% of variation in kidney cancer behaviour is not due to changes in DNA
Researchers at the Francis Crick Institute have shown that over 40% of variation in kidney cancer behaviour is due to non-genetic factors. These could be targeted by new treatments or help doctors und...
www.crick.ac.uk
January 8, 2025 at 3:27 PM
Researchers from the Crick have found that over 40% of variation in the way kidney cancer behaves is due to non-genetic factors.
The findings were led by Angel Fernandez Sanroman with senior author Samra Turajlic
www.crick.ac.uk/news-and-rep...
The findings were led by Angel Fernandez Sanroman with senior author Samra Turajlic
www.crick.ac.uk/news-and-rep...
Reposted by Elisabetta Mereu
Excited to share our new study of #genomics🧬, #EHR📈 + treatment outcomes of 78K patients across 20 #cancers!
We identified >700 mutations predicting which drugs💊 are effective for individual patients. Our #ML model predicts who responds well to immunotherapies. #precisioncancer
We identified >700 mutations predicting which drugs💊 are effective for individual patients. Our #ML model predicts who responds well to immunotherapies. #precisioncancer
January 8, 2025 at 3:45 PM
Excited to share our new study of #genomics🧬, #EHR📈 + treatment outcomes of 78K patients across 20 #cancers!
We identified >700 mutations predicting which drugs💊 are effective for individual patients. Our #ML model predicts who responds well to immunotherapies. #precisioncancer
We identified >700 mutations predicting which drugs💊 are effective for individual patients. Our #ML model predicts who responds well to immunotherapies. #precisioncancer
Reposted by Elisabetta Mereu
scRepertoire 2: Enhanced and Efficient Toolkit for Single-Cell Immune Profiling
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
December 31, 2024 at 8:11 PM
scRepertoire 2: Enhanced and Efficient Toolkit for Single-Cell Immune Profiling
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Join us to decode the immune system with AI and advance immunotherapy research.
🌍 Part of RAMON LLULL - AIRA: 33 prestigious international postdoc fellowships.
📅 Apply by Feb 20. Start June 2025.
🔗 ramonllull-aira.eu
📩 emereu@carrerasresearch.org
#AI #Postdoc #Genomics #Immunotherapy #Research
🌍 Part of RAMON LLULL - AIRA: 33 prestigious international postdoc fellowships.
📅 Apply by Feb 20. Start June 2025.
🔗 ramonllull-aira.eu
📩 emereu@carrerasresearch.org
#AI #Postdoc #Genomics #Immunotherapy #Research
December 22, 2024 at 11:38 AM
Join us to decode the immune system with AI and advance immunotherapy research.
🌍 Part of RAMON LLULL - AIRA: 33 prestigious international postdoc fellowships.
📅 Apply by Feb 20. Start June 2025.
🔗 ramonllull-aira.eu
📩 emereu@carrerasresearch.org
#AI #Postdoc #Genomics #Immunotherapy #Research
🌍 Part of RAMON LLULL - AIRA: 33 prestigious international postdoc fellowships.
📅 Apply by Feb 20. Start June 2025.
🔗 ramonllull-aira.eu
📩 emereu@carrerasresearch.org
#AI #Postdoc #Genomics #Immunotherapy #Research