Duong Bui
duongtbui.bsky.social
Duong Bui
@duongtbui.bsky.social
native mass spectrometry, glycobiology, SLOMO
Reposted by Duong Bui
Save the date for #GIA2026 (Nov. 5-6, 2026) which will feature free #glycotime talks by @carolynbertozzi.bskyverified.social , Dr. Mia Huang and more!
November 8, 2025 at 12:38 AM
Reposted by Duong Bui
The countdown is on! With GIA2025 less than 3 weeks away, we’d like to introduce our Keynote Speakers that we will have the privilege of hosting this year. First is Dr. Sriram Neelameghan from the University at Buffalo whose lab studies the area of Systems Glycobiology. @neel-lab.bsky.social
October 20, 2025 at 9:57 PM
Excited to share that our latest paper is now published in JASMS!
pubs.acs.org/doi/10.1021/...
October 20, 2025 at 8:09 PM
Reposted by Duong Bui
#glycotime alert! Zhiyong synthesized O-acetylated GD3 gangliosides, which were used to examine viral receptor specificities in a cellular context by @LiangRuonan great work by @zeshi_li and @TheBoonsGroup @uu-cbdd.bsky.social www.biorxiv.org/content/10.1...
Chemoenzymatically Synthesized O-Acetylated GD3 Gangliosides to Examine Viral Receptor Specificities in a Cellular Context
Gangliosides are a class of sialic acid-containing glycosphingolipids involved in a wide range of biological processes. The terminal sialic acid of gangliosides can be O -acetylated at C7 and/or C9 hy...
www.biorxiv.org
August 26, 2025 at 12:20 PM
Reposted by Duong Bui
Preprint: upregulation by #miRNA conserved for millions of yrs. Site on #OGT in multiple CLIP studies- upregulates protein. 8th gene in lit where we identified upreg. sites. Proud of Zainab Ali, @faezehjame.bsky.social, Hallie Ng, and Thu Chu #RNAsky #RNA #glycotime
www.biorxiv.org/content/10.1...
Analyzing the miRNA regulatory landscape of OGT identifies evolutionarily conserved upregulation.
O-GlcNAc transferase (OGT) is the key enzyme involved in post-translationally modifying cytoplasmic and nuclear proteins with O-GlcNAc. Maintenance of cellular O-GlcNAcylation levels is critical to ce...
www.biorxiv.org
August 25, 2025 at 4:17 PM
#TeamMassSpec — Ever wondered what governs mass transport and mixing inside nanoESI emitters?
📢 Here, we report the first quantitative investigation of the factors driving solution mixing and analyte transport in a nanoESI emitter:
chemrxiv.org/engage/chemr...
Going with the Flow: Mechanistic Insights into Slow Mixing Mode Native Mass Spectrometry
Slow mixing mode native mass spectrometry (SLOMO-nMS), which monitors the mixing of layered solutions within a nanoflow electrospray ionization (nanoESI) emitter, enables robust quantification of biom...
chemrxiv.org
July 15, 2025 at 4:47 PM
🚨 Just published in Mass Spectrometry Reviews! 🚨
Thrilled to share our latest review, summarizing over 20 years of work from the Klassen lab —plus insights from my own PhD research on COIN-nMS, SLOMO-nMS, and charge detection MS.
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
Interactions between glycan-binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan i...
analyticalsciencejournals.onlinelibrary.wiley.com
June 30, 2025 at 4:57 PM
Reposted by Duong Bui
When glycan recognition is linked to immune response, you need fine tuning! 😎

Here ⬇️ we show how human Siglecs act as molecular precision tools, recognising the glycan and also the biological environment (or context) these glycans are found in. A 1/5 #glycotime🧵 ⬇️

doi.org/10.1101/2025...
June 22, 2025 at 10:42 AM
Reposted by Duong Bui
By deep characterisation of 186 N-glycan standards, we @thencfg.bsky.social have made the most comprehensive targeted LC-MS glycomic assay to date.
Non-reduced native glycan analysis is key.
We hope this enables anyone with QqQ and interest in #glycotime to measure specific N-glycan structures.
June 10, 2025 at 1:11 PM
#ASMS2025 was a wonderful #TeamMassSpec experience. Our session chaired by @lingjun2025.bsky.social was awesome with great talks. Having the shuttle buses arranged was an incredibly thoughtful touch.
My personal version of Faces of MS this year:
June 6, 2025 at 2:03 PM
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Mass spectrometrist looking for a postdoc? Why not in Switzerland 🇨🇭
We are reinforcing our team in Geneva ⤵️
www.linkedin.com/posts/valeri...
Mass spectrometry post-doc position in Switzerland | Valerie Gabelica
🔊 Mass spectrometry post-doc position in Switzerland Join our dynamic and interdisciplinary team for a post-doc in Geneva, Switzerland, where we develop advanced mass spectrometry methods for biophysi...
www.linkedin.com
April 10, 2025 at 7:54 PM