Nath Jones
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drnathjones.bsky.social
Nath Jones
@drnathjones.bsky.social
Researches parasites and how to kill them. Leishmania epigenetics & transcriptional regulation. Currently in York.
Reposted by Nath Jones
🚨Attention prospective PhD students🚨
Are you interested in molecular mechanisms, RNA viruses, structural biology or biophysics? 🧬🦠🧪

We have THREE fully-funded PhD projects available for October 2026 entry:
www.findaphd.com/phds/?Keywor...

Please share/repost, and get in touch if you're interested
chris hill PhD Projects, Programmes & Scholarships - 3 PhDs Listed
FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in chris hill. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.
www.findaphd.com
November 13, 2025 at 7:54 PM
Reposted by Nath Jones
We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM.

Please get in touch if you are interested in joining this amazing team! 🔬🧬🤩
#RNA #cryoEM
September 27, 2025 at 11:07 AM
Reposted by Nath Jones
[We are Hiring!]

The Weiss Lab at Albert Einstein College of Medicine (NY) is hiring a Postdoc Scientist to explore the Toxoplasma gondii cyst wall using XL-MS, Split TurboID, & U-ExM.

This project aims to unlock new strategies for treating toxoplasmosis.

DM for more info!
September 17, 2025 at 4:28 PM
Reposted by Nath Jones
📣 Open postdoc position in my lab to investigate how Toxoplasma acquires nutrients. Join me at the University of Edinburgh. Closing date 14th August. More details below ⬇️

elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Postdoctoral Research Associate
We are looking for a talented and enthusiastic Postdoctoral researcher to join the Maclean lab to investigate the metabolism of the human parasite Toxoplasma gondii.
elxw.fa.em3.oraclecloud.com
July 23, 2025 at 10:00 AM
Reposted by Nath Jones
Better late than never, but I am thrilled to share our newest research from the Treeck lab!!! www.nature.com/articles/s41...
The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound - Nature Microbiology
FIKK effector kinases underwent rapid evolutionary expansion and are a druggable target in Plasmodium falciparum.
www.nature.com
June 23, 2025 at 1:28 PM
Reposted by Nath Jones
So happy to share the first preprint from our lab on post-transcriptional regulation at the VSG expression-site body in trypanosomes. @ybri-uoy.bsky.social @york.ac.uk
Specialised RNA decay fine-tunes monogenic antigen expression in African trypanosomes
Antigenic variation is a sophisticated immune evasion strategy employed by many pathogens. Trypanosoma brucei expresses a single Variant-Surface-Glycoprotein (VSG) from a large genetic repertoire, whi...
www.biorxiv.org
May 27, 2025 at 10:28 AM
Reposted by Nath Jones
Our latest collaborative work with Keith Matthews’ lab using synthetic DNA binding proteins to explore the chromatin protein contexts of repetitive sequences in Trypanosoma brucei in now on bioRxiv - thanks to all involved! 2025.04.22.649942; doi: doi.org/10.1101/2025...
Defining the chromatin-associated protein landscapes on Trypanosoma brucei repetitive elements using synthetic TALE proteins
Kinetoplastids, such as Trypansoma brucei, are eukaryotes that likely separated from the main lineage at an exceptionally early point in evolution. Consequently, many aspects of kinetoplastid biology ...
doi.org
April 24, 2025 at 12:11 PM
Reposted by Nath Jones
We have a 3-year PDRA post in Cancer Immunogenomics. Ideal to use and strengthen your bioinformatics skills to discover how cancer transcriptome quirks shape immunotherapy outcomes. Funded by @cancerresearchuk.org. It’ll be fun!
jobs.york.ac.uk/vacancy/rese...
@hyms.ac.uk
@ybri-uoy.bsky.social
Jobs - The University of York
jobs.york.ac.uk
April 22, 2025 at 9:56 AM
Reposted by Nath Jones
Keep VEuPathDB open-access to all by subscribing today! veupathdb.org/veupathdb/ap...
April 21, 2025 at 2:58 PM
Reposted by Nath Jones
Glad this is finally out. Using pharmacokinetic modeling we show that #nitisinone, an FDA-approved drug 4 #Tyrosinemia & #Alkaptonuria, kills #Anopheles mosquitoes, outperforming #Ivermectin. Grateful to all primary author’s & fantastic collaborators!

www.science.org/doi/10.1126/...
Anopheles mosquito survival and pharmacokinetic modeling show the mosquitocidal activity of nitisinone
Nitisinone reduces survival of the malaria-transmitting mosquito Anopheles gambiae by blocking tyrosine catabolism.
www.science.org
March 26, 2025 at 8:21 PM
New preprint: results from a collaborative project funded by the GCRF Global Network for NTDs investigating Leishmania deubiquitinase 16 as a potential drug target. @ybri-uoy.bsky.social @mottramlab.bsky.social www.biorxiv.org/content/10.1...
Structure and Activity of the Essential UCH Family Deubiquitinase DUB16 from Leishmania donovani
In Leishmania parasites, as for their hosts, the ubiquitin proteasome system is important for cell viability. As part of a systematic gene deletion study, it was discovered that four cysteine protease...
www.biorxiv.org
March 4, 2025 at 11:03 AM
Reposted by Nath Jones
🥁🥁 Job alertttt!! Interested in weird biology of malaria parasites? Inducible genetic screens? Single-cell RNAseq? Come postdoc with us - www.parafugelab.com ! International applicants or applicants just finishing up their PhD, both welcome!!

www.jobs.gla.ac.uk/job/research...
Research Assistant/Associate
Job Purpose We are seeking to recruit a motivated and creative Research Assistant/Associate (postdoctoral researcher) to work within an MRC-funded research programme https://gtr.ukri.org/projects?...
www.jobs.gla.ac.uk
January 17, 2025 at 11:50 AM
Reposted by Nath Jones
Is there a way to download all of NIH Bioart (in case it is taken offline by the current regime in the USA)?

bioart.niaid.nih.gov/discover
Bioart
bioart.niaid.nih.gov
January 22, 2025 at 10:14 PM
Reposted by Nath Jones
MRC- funded PhD project at the interface between biology & physics to investigate the segregation of an antibiotic resistant plasmid. Interdisciplinary training with super supportive supervisors.

In the beautiful historic city of York.

Please re-post, thanks! #microsky
🦠🧫🧪
📆17 December
December 3, 2023 at 9:06 AM
Happy to see this now online at ACS Infectious Diseases . Catherine & the team did a great job on the initial structural & biophysical assessment of BDF5 bromodomains as potential drug targets in Leishmania. #parasite #epigenetics

t.co/UoI9i1NSux
November 1, 2023 at 8:19 PM
Hello Bluesky
October 25, 2023 at 6:58 PM