Jessica Hartman
@drjhartman.bsky.social
Assistant Prof @ MUSC Biochemistry studying metabolism! Personal account.
So excited to share our new work led by my awesome PhD student Hyland Gonzalez. She shows transcriptional effects of CYP2E1 deletion in alcohol naive mice and then goes on to show that mice lacking CYP2E1 drink more at baseline and escalate their drinking more after CIE compared to WT mice. 🍸🐁
Check out my new paper on how Cyp2e1 deletion results in increased sensitivity to ethanol-induced motor impairment and increased drinking escalation in a CIE model:
doi.org/10.1111/acer...
doi.org/10.1111/acer...
Cyp2e1 deletion in mice increases sensitivity to ethanol‐induced motor impairment and escalation of drinking behavior in the chronic intermittent ethanol model
This study investigates the impact of global Cyp2e1 knockout and wild-type mice to explore the effect of altered ethanol metabolism on behavior and gene expression. Knockout mice demonstrated altered...
doi.org
November 6, 2025 at 11:58 PM
So excited to share our new work led by my awesome PhD student Hyland Gonzalez. She shows transcriptional effects of CYP2E1 deletion in alcohol naive mice and then goes on to show that mice lacking CYP2E1 drink more at baseline and escalate their drinking more after CIE compared to WT mice. 🍸🐁
Reposted by Jessica Hartman
“It actually doesn’t take much to be considered a difficult woman. That’s why there are so many of us.”
― Jane Goodall
💙 RIP to a real one. My childhood hero
― Jane Goodall
💙 RIP to a real one. My childhood hero
October 2, 2025 at 2:56 AM
“It actually doesn’t take much to be considered a difficult woman. That’s why there are so many of us.”
― Jane Goodall
💙 RIP to a real one. My childhood hero
― Jane Goodall
💙 RIP to a real one. My childhood hero
Reposted by Jessica Hartman
"Our observations should prompt an essential re-evaluation of the literature concerning astrocyte-neuron mitochondrial transfer" www.biorxiv.org/content/10.1...
MitoTracker transfers from astrocytes to neurons independently of mitochondria
The neuroprotective transfer of mitochondria from astrocytes to neurons has been primarily investigated by labelling astrocytic mitochondria with the dye MitoTracker. Here we report that MitoTracker transfers to neurons from both astrocytes and astrocyte-conditioned media, independently of mitochondrial transfer. Our observations should prompt an essential re-evaluation of the literature concerning astrocyte-neuron mitochondrial transfer and in other systems in which contact-independent transfer has been observed using mitochondrial dyes. ### Competing Interest Statement The authors have declared no competing interest. MSD (United Kingdom), https://ror.org/004nn4n27, PRJ_20446 DEVINE MSD MRC The Francis Crick Institute, https://ror.org/04tnbqb63, CC2206
www.biorxiv.org
July 8, 2025 at 10:45 PM
"Our observations should prompt an essential re-evaluation of the literature concerning astrocyte-neuron mitochondrial transfer" www.biorxiv.org/content/10.1...
Reposted by Jessica Hartman
For #worm25, here are updated lists of 200+ researchers for the #Celegans community to easily follow:
C. elegans #1 (150 full) - go.bsky.app/HP1h3nW
C. elegans #2 (50+) - go.bsky.app/J7soTHG
==> Reply to this if you'd like to be added!
cc: @genetics-gsa.bsky.social
#CeleganSky 🪱 🧪 1/n
C. elegans #1 (150 full) - go.bsky.app/HP1h3nW
C. elegans #2 (50+) - go.bsky.app/J7soTHG
==> Reply to this if you'd like to be added!
cc: @genetics-gsa.bsky.social
#CeleganSky 🪱 🧪 1/n
June 29, 2025 at 7:20 PM
For #worm25, here are updated lists of 200+ researchers for the #Celegans community to easily follow:
C. elegans #1 (150 full) - go.bsky.app/HP1h3nW
C. elegans #2 (50+) - go.bsky.app/J7soTHG
==> Reply to this if you'd like to be added!
cc: @genetics-gsa.bsky.social
#CeleganSky 🪱 🧪 1/n
C. elegans #1 (150 full) - go.bsky.app/HP1h3nW
C. elegans #2 (50+) - go.bsky.app/J7soTHG
==> Reply to this if you'd like to be added!
cc: @genetics-gsa.bsky.social
#CeleganSky 🪱 🧪 1/n
June 30, 2025 at 11:58 PM
Reposted by Jessica Hartman
The Spencer Foundation is offering rapid response bridge funding for those who lost NSF research grants.
www.spencer.org/grant_types/...
www.spencer.org/grant_types/...
Rapid Response Bridge Funding Program
In the face of recent abrupt shifts in federal funding for education research, including large-scale terminations of National Science Foundation (NSF) research grant awards, we have developed a rap...
www.spencer.org
May 2, 2025 at 9:07 PM
The Spencer Foundation is offering rapid response bridge funding for those who lost NSF research grants.
www.spencer.org/grant_types/...
www.spencer.org/grant_types/...
Reposted by Jessica Hartman
‘Kennedy told reporters that there were "many, many good ways to treat measles and doctors need to know that and to know those methods.’
One problem; there is no treatment for measles. Signed, a doctor who’s been forced to deal with measles because of this stupid fraud.
One problem; there is no treatment for measles. Signed, a doctor who’s been forced to deal with measles because of this stupid fraud.
RFK Jr. asks CDC for new measles treatment guidance amid his unfounded claims
Kennedy claimed that drugs like budesonide and clarithromycin "have been shown very effective" for measles, but doctors say they don't fight the infection itself.
www.cbsnews.com
May 2, 2025 at 3:11 AM
‘Kennedy told reporters that there were "many, many good ways to treat measles and doctors need to know that and to know those methods.’
One problem; there is no treatment for measles. Signed, a doctor who’s been forced to deal with measles because of this stupid fraud.
One problem; there is no treatment for measles. Signed, a doctor who’s been forced to deal with measles because of this stupid fraud.
Reposted by Jessica Hartman
RFK Jr. is very loud and very WRONG about Autism.
1. It’s not a disease
2. There are thousands of people with Autism Spectrum Disorder who pay taxes, have jobs, can use the bathroom on their own, and are thriving in life.
1. It’s not a disease
2. There are thousands of people with Autism Spectrum Disorder who pay taxes, have jobs, can use the bathroom on their own, and are thriving in life.
April 17, 2025 at 6:10 PM
RFK Jr. is very loud and very WRONG about Autism.
1. It’s not a disease
2. There are thousands of people with Autism Spectrum Disorder who pay taxes, have jobs, can use the bathroom on their own, and are thriving in life.
1. It’s not a disease
2. There are thousands of people with Autism Spectrum Disorder who pay taxes, have jobs, can use the bathroom on their own, and are thriving in life.
Reposted by Jessica Hartman
I have tariffed
the penguins
that are on
Heard Island
and which
you were probably
assuming
did not export goods
forgive me
they were taking advantage of us
so cunning
and so cold
the penguins
that are on
Heard Island
and which
you were probably
assuming
did not export goods
forgive me
they were taking advantage of us
so cunning
and so cold
April 3, 2025 at 7:45 PM
I have tariffed
the penguins
that are on
Heard Island
and which
you were probably
assuming
did not export goods
forgive me
they were taking advantage of us
so cunning
and so cold
the penguins
that are on
Heard Island
and which
you were probably
assuming
did not export goods
forgive me
they were taking advantage of us
so cunning
and so cold
Reposted by Jessica Hartman
I’ve taken the Senate floor and will speak for as long as I’m physically able to lift the voices of Americans who are being harmed and not being heard in this moment of crisis. Watch here:
Live: Speaking on Trump, Musk, and America’s Moral Moment on the Senate Floor | Senator Cory Booker
YouTube video by Senator Cory Booker
youtube.com
March 31, 2025 at 11:00 PM
I’ve taken the Senate floor and will speak for as long as I’m physically able to lift the voices of Americans who are being harmed and not being heard in this moment of crisis. Watch here:
Reposted by Jessica Hartman
Would not have thought that the first person in congress to strongly defend researh would be a republican but more powerful that it is. www.washingtonpost.com/opinions/202...
Opinion | Funding for R&D isn’t a gift to academia
Investing in scientific research and development is vital to U.S. security.
www.washingtonpost.com
March 30, 2025 at 10:32 PM
Would not have thought that the first person in congress to strongly defend researh would be a republican but more powerful that it is. www.washingtonpost.com/opinions/202...
Reposted by Jessica Hartman
🚨 Attention NIH & NSF grantees!
AAAS is hosting a rapid response webinar this Friday, 12-1 pm ET, on responding to federal research grant terminations.
NIH and NSF will be case examples.
Register here: aaas.zoom.us/webinar/regi...
AAAS is hosting a rapid response webinar this Friday, 12-1 pm ET, on responding to federal research grant terminations.
NIH and NSF will be case examples.
Register here: aaas.zoom.us/webinar/regi...
March 25, 2025 at 6:44 PM
🚨 Attention NIH & NSF grantees!
AAAS is hosting a rapid response webinar this Friday, 12-1 pm ET, on responding to federal research grant terminations.
NIH and NSF will be case examples.
Register here: aaas.zoom.us/webinar/regi...
AAAS is hosting a rapid response webinar this Friday, 12-1 pm ET, on responding to federal research grant terminations.
NIH and NSF will be case examples.
Register here: aaas.zoom.us/webinar/regi...
Reposted by Jessica Hartman
We've been tracking unlawful NIH grant terminations for 3 weeks. Spread the word👇!
Fellow PIs: what can you do upon termination?
✅ Email PO + document questions
✅ Submit FOIA
✅ Advocate to your OCG/OSP for appeal + litigation
✅ Consider outside litigation
✅ Donate to state AGs + legal orgs
1/🧵
Fellow PIs: what can you do upon termination?
✅ Email PO + document questions
✅ Submit FOIA
✅ Advocate to your OCG/OSP for appeal + litigation
✅ Consider outside litigation
✅ Donate to state AGs + legal orgs
1/🧵
Cancelled NIH grant information submission form
Please use this form to submit information identifying specific NIH grants that have been cancelled for any reason after January 20, 2025.
Data from this form will be used to update the Rescinded NIH...
docs.google.com
March 21, 2025 at 10:38 AM
We've been tracking unlawful NIH grant terminations for 3 weeks. Spread the word👇!
Fellow PIs: what can you do upon termination?
✅ Email PO + document questions
✅ Submit FOIA
✅ Advocate to your OCG/OSP for appeal + litigation
✅ Consider outside litigation
✅ Donate to state AGs + legal orgs
1/🧵
Fellow PIs: what can you do upon termination?
✅ Email PO + document questions
✅ Submit FOIA
✅ Advocate to your OCG/OSP for appeal + litigation
✅ Consider outside litigation
✅ Donate to state AGs + legal orgs
1/🧵
Reposted by Jessica Hartman
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
March 22, 2025 at 10:44 AM
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
Reposted by Jessica Hartman
I still love teaching and think it matters, God help me
March 21, 2025 at 5:32 PM
I still love teaching and think it matters, God help me
Reposted by Jessica Hartman
chatgpt has fully broken-through to every facet of the corporate environment. I'm spending a not-insignificant amount of my time every week now explaining to people that just because chatgpt told you that something was possible doesn't mean that it a) is or b) even exists
March 21, 2025 at 1:44 PM
chatgpt has fully broken-through to every facet of the corporate environment. I'm spending a not-insignificant amount of my time every week now explaining to people that just because chatgpt told you that something was possible doesn't mean that it a) is or b) even exists
Reposted by Jessica Hartman
In 15 yrs of reporting, I've never had so many health & biomed researchers & outreach orgs tell me they're afraid to talk w/press or barred from speaking bc of new comms policies.
I understand the fear of losing funds. I don't know if silence does more harm than good. If you can speak up, pls do.
I understand the fear of losing funds. I don't know if silence does more harm than good. If you can speak up, pls do.
March 21, 2025 at 2:27 PM
In 15 yrs of reporting, I've never had so many health & biomed researchers & outreach orgs tell me they're afraid to talk w/press or barred from speaking bc of new comms policies.
I understand the fear of losing funds. I don't know if silence does more harm than good. If you can speak up, pls do.
I understand the fear of losing funds. I don't know if silence does more harm than good. If you can speak up, pls do.
Reposted by Jessica Hartman
NIH spending more than pays for itself. It generates about $2.5 for every $1 spent. In terms of research productivity, NIH funding dwarfs the rest of the world. The only long-term potential rival is China. Politicizing the NIH's scientific processes will hand China a huge strategic advantage.
March 20, 2025 at 1:11 PM
NIH spending more than pays for itself. It generates about $2.5 for every $1 spent. In terms of research productivity, NIH funding dwarfs the rest of the world. The only long-term potential rival is China. Politicizing the NIH's scientific processes will hand China a huge strategic advantage.
Reposted by Jessica Hartman
I now have multiple sources that say at least one round of NATIONAL ADVISORY COUNCIL MEETINGS will now be announced in the Federal Register.
a muppet news anchor says " and now a muppet news flash " while holding a piece of paper
ALT: a muppet news anchor says " and now a muppet news flash " while holding a piece of paper
media.tenor.com
March 14, 2025 at 9:52 PM
I now have multiple sources that say at least one round of NATIONAL ADVISORY COUNCIL MEETINGS will now be announced in the Federal Register.
Reposted by Jessica Hartman
Just thinking about what the US looked like before the EPA existed
March 13, 2025 at 2:47 PM
Just thinking about what the US looked like before the EPA existed
Reposted by Jessica Hartman
Meeting the person you suspect is reviewer #2 in a conference
March 13, 2025 at 9:11 PM
Meeting the person you suspect is reviewer #2 in a conference
Reposted by Jessica Hartman
Reposted by Jessica Hartman
Having had a kid die of measles in my arms as a doctor in the DR Congo, I respectfully disagree that this would be better. Vaccines save lives.
www.thedailybeast.com/rfk-jr-it-wo...
www.thedailybeast.com/rfk-jr-it-wo...
RFK Jr.: It Would Be Better if ‘Everybody Got Measles’
“The measles gave you lifetime protection against measles infection,” Robert F. Kennedy Jr. told Sean Hannity on Fox News.
www.thedailybeast.com
March 12, 2025 at 7:42 PM
Having had a kid die of measles in my arms as a doctor in the DR Congo, I respectfully disagree that this would be better. Vaccines save lives.
www.thedailybeast.com/rfk-jr-it-wo...
www.thedailybeast.com/rfk-jr-it-wo...
Reposted by Jessica Hartman
Terrific and sorrowful thread
🧪 The NSF director is lying to you.
Let’s fact check 7 claims from yesterday’s letter to the community, while pointing out 3 critical omissions. 🧵
Let’s fact check 7 claims from yesterday’s letter to the community, while pointing out 3 critical omissions. 🧵
March 12, 2025 at 4:46 PM
Terrific and sorrowful thread
Reposted by Jessica Hartman
