Sebastian Bruchmann
@doktorbasti.bsky.social
Assistant Research Professor @ University of Cambridge / HLRI
Functional Genomics, AMR and Host Pathogen Interactions of Klebsiella pneumoniae and Pseudomonas aeruginosa
https://sebbruchmann.github.io/
Functional Genomics, AMR and Host Pathogen Interactions of Klebsiella pneumoniae and Pseudomonas aeruginosa
https://sebbruchmann.github.io/
Reposted by Sebastian Bruchmann
We are hiring! 🎓🧫 🧬
#PhD studentship available in #Immunology at #CambridgeUniversity to investigate a new killer function of human T cells.
📅 Application deadline: 3rd December 2025
more information: lnkd.in/dxq6yMay
#findaPhD @ERC_Research
#PhD studentship available in #Immunology at #CambridgeUniversity to investigate a new killer function of human T cells.
📅 Application deadline: 3rd December 2025
more information: lnkd.in/dxq6yMay
#findaPhD @ERC_Research
November 5, 2025 at 9:22 AM
We are hiring! 🎓🧫 🧬
#PhD studentship available in #Immunology at #CambridgeUniversity to investigate a new killer function of human T cells.
📅 Application deadline: 3rd December 2025
more information: lnkd.in/dxq6yMay
#findaPhD @ERC_Research
#PhD studentship available in #Immunology at #CambridgeUniversity to investigate a new killer function of human T cells.
📅 Application deadline: 3rd December 2025
more information: lnkd.in/dxq6yMay
#findaPhD @ERC_Research
Reposted by Sebastian Bruchmann
🚨 Another funded PhD alert🚨
We are recruiting again! For a PhD student to start with us in the @langridgelab.bsky.social October 2026 - please share 👀
If you are interested in foodborne pathogens, public health and phage, look no further 🦠🏥🧬
➡️ tinyurl.com/3zvavp2t ⬅️
Apply by 6 Jan 2026 🗓️
We are recruiting again! For a PhD student to start with us in the @langridgelab.bsky.social October 2026 - please share 👀
If you are interested in foodborne pathogens, public health and phage, look no further 🦠🏥🧬
➡️ tinyurl.com/3zvavp2t ⬅️
Apply by 6 Jan 2026 🗓️
October 28, 2025 at 1:17 PM
🚨 Another funded PhD alert🚨
We are recruiting again! For a PhD student to start with us in the @langridgelab.bsky.social October 2026 - please share 👀
If you are interested in foodborne pathogens, public health and phage, look no further 🦠🏥🧬
➡️ tinyurl.com/3zvavp2t ⬅️
Apply by 6 Jan 2026 🗓️
We are recruiting again! For a PhD student to start with us in the @langridgelab.bsky.social October 2026 - please share 👀
If you are interested in foodborne pathogens, public health and phage, look no further 🦠🏥🧬
➡️ tinyurl.com/3zvavp2t ⬅️
Apply by 6 Jan 2026 🗓️
Fantastic paper: "Dual transposon sequencing profiles the genetic interaction landscape in bacteria" out now in Science www.science.org/doi/10.1126/...
September 26, 2025 at 11:42 AM
Fantastic paper: "Dual transposon sequencing profiles the genetic interaction landscape in bacteria" out now in Science www.science.org/doi/10.1126/...
Reposted by Sebastian Bruchmann
Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols.
Thread 1/n
Thread 1/n
September 25, 2025 at 9:29 PM
Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols.
Thread 1/n
Thread 1/n
Reposted by Sebastian Bruchmann
OK, here it is. Come work with me at the University of Liverpool making ALL THE AI models from ALL THE prokaryote pangenome data. Heck, we will make models from ALL the pangenomes, even eukaryotes!!! (link below👇) 1/4
September 25, 2025 at 9:49 AM
OK, here it is. Come work with me at the University of Liverpool making ALL THE AI models from ALL THE prokaryote pangenome data. Heck, we will make models from ALL the pangenomes, even eukaryotes!!! (link below👇) 1/4
Reposted by Sebastian Bruchmann
PLEASE RETWEET.
The lab github is here: github.com/mol-evol/ so you can get an idea of what we have been working on recently (several projects are private at the moment, so this will be bigger soon) and the job ad is here: www.jobs.ac.uk/job/DOU184/p...
Postdoctoral Research Associate - Grade 7 at University of Liverpool
Apply now for the Postdoctoral Research Associate - Grade 7 role on jobs.ac.uk - the leading job board for higher education jobs. View details.
www.jobs.ac.uk
September 25, 2025 at 10:08 AM
PLEASE RETWEET.
Reposted by Sebastian Bruchmann
Come and work with Nicole Stoesser and I in Oxford with the fantastic team @modmedmicro.bsky.social - great opportunity for a postdoc in microbial genomics to do some creative research with great datasets as part of our HPRU.
my.corehr.com/pls/uoxrecru...
my.corehr.com/pls/uoxrecru...
Job Details
my.corehr.com
September 23, 2025 at 9:47 AM
Come and work with Nicole Stoesser and I in Oxford with the fantastic team @modmedmicro.bsky.social - great opportunity for a postdoc in microbial genomics to do some creative research with great datasets as part of our HPRU.
my.corehr.com/pls/uoxrecru...
my.corehr.com/pls/uoxrecru...
Had a brilliant time in Liverpool at Edge Hill University for the Galleria mellonella Workshop 🐛
Grateful to be invited as a speaker, the great chats and new connections. Amazing to see the wide range of applications, hope our time lapse imaging work can add to the field!
Grateful to be invited as a speaker, the great chats and new connections. Amazing to see the wide range of applications, hope our time lapse imaging work can add to the field!
September 16, 2025 at 10:03 AM
Had a brilliant time in Liverpool at Edge Hill University for the Galleria mellonella Workshop 🐛
Grateful to be invited as a speaker, the great chats and new connections. Amazing to see the wide range of applications, hope our time lapse imaging work can add to the field!
Grateful to be invited as a speaker, the great chats and new connections. Amazing to see the wide range of applications, hope our time lapse imaging work can add to the field!
Reposted by Sebastian Bruchmann
Willing to join us @pasteur.fr for a PhD for a project on how interactions between mobile genetic elements shape bacterial adaptation? Subject to be tailored to candidates with keen interest in evolution, genomics, computational biology, microbiology. Check www.pasteur.fr/en/education...
September 8, 2025 at 8:56 AM
Willing to join us @pasteur.fr for a PhD for a project on how interactions between mobile genetic elements shape bacterial adaptation? Subject to be tailored to candidates with keen interest in evolution, genomics, computational biology, microbiology. Check www.pasteur.fr/en/education...
Reposted by Sebastian Bruchmann
Our latest preprint is out describing amr.watch - a platform for monitoring AMR trends from global genomics data: www.biorxiv.org/content/10.1... (1/6)
April 22, 2025 at 9:54 AM
Our latest preprint is out describing amr.watch - a platform for monitoring AMR trends from global genomics data: www.biorxiv.org/content/10.1... (1/6)
Reposted by Sebastian Bruchmann
Our review on recent advances in #PhageTherapy against Klebsiella pneumoniae is out!
We analyze KP-phage interactions from an eco-evo perspective, summarize many lab and clinical trials, and discuss novel approaches like genetic engineering & machine learning.
#microsky
doi.org/10.1371/jour...
We analyze KP-phage interactions from an eco-evo perspective, summarize many lab and clinical trials, and discuss novel approaches like genetic engineering & machine learning.
#microsky
doi.org/10.1371/jour...
Phage therapy for Klebsiella pneumoniae: Understanding bacteria–phage interactions for therapeutic innovations
Klebsiella pneumoniae (KP) is a Gram-negative bacterium that commonly resides in the human gastrointestinal tract and can also act as an opportunistic pathogen and cause extra-intestinal infections. K...
doi.org
April 9, 2025 at 10:10 AM
Our review on recent advances in #PhageTherapy against Klebsiella pneumoniae is out!
We analyze KP-phage interactions from an eco-evo perspective, summarize many lab and clinical trials, and discuss novel approaches like genetic engineering & machine learning.
#microsky
doi.org/10.1371/jour...
We analyze KP-phage interactions from an eco-evo perspective, summarize many lab and clinical trials, and discuss novel approaches like genetic engineering & machine learning.
#microsky
doi.org/10.1371/jour...
Reposted by Sebastian Bruchmann
I've spent some time updating my two Nextflow-based bacterial QC pipelines (bacQC and bacQC-ONT). It'd be great to get some feedback.
github.com/avantonder/b...
github.com/avantonder/b...
github.com/avantonder/b...
github.com/avantonder/b...
GitHub - avantonder/bacQC-ONT: QC pipeline for ONT data
QC pipeline for ONT data. Contribute to avantonder/bacQC-ONT development by creating an account on GitHub.
github.com
March 6, 2025 at 10:47 AM
I've spent some time updating my two Nextflow-based bacterial QC pipelines (bacQC and bacQC-ONT). It'd be great to get some feedback.
github.com/avantonder/b...
github.com/avantonder/b...
github.com/avantonder/b...
github.com/avantonder/b...
Reposted by Sebastian Bruchmann
Free #bioinformatics toolkit for #biologists!
Master #Linux, basic scripting, and advanced Nextflow pipelines, with our #OnlineCourses that guide you through complete bioinformatics workflows.
Gain deeper insights from your biological research🚀
📎 Info: bit.ly/4aMV22B
Master #Linux, basic scripting, and advanced Nextflow pipelines, with our #OnlineCourses that guide you through complete bioinformatics workflows.
Gain deeper insights from your biological research🚀
📎 Info: bit.ly/4aMV22B
February 10, 2025 at 12:50 PM
Free #bioinformatics toolkit for #biologists!
Master #Linux, basic scripting, and advanced Nextflow pipelines, with our #OnlineCourses that guide you through complete bioinformatics workflows.
Gain deeper insights from your biological research🚀
📎 Info: bit.ly/4aMV22B
Master #Linux, basic scripting, and advanced Nextflow pipelines, with our #OnlineCourses that guide you through complete bioinformatics workflows.
Gain deeper insights from your biological research🚀
📎 Info: bit.ly/4aMV22B
Reposted by Sebastian Bruchmann
Brochado and Maier labs in Germany are looking for a PhD student to study horizontal gene transfer in bacteria. ENDAMR Marie Curie doctoral network (endamr.eu) - an amazing opportunity to work with top scientists in the field all around Europe!
www.cmfi.uni-tuebingen.de/mariecuriephd
www.cmfi.uni-tuebingen.de/mariecuriephd
endamr.eu
February 20, 2025 at 9:15 AM
Brochado and Maier labs in Germany are looking for a PhD student to study horizontal gene transfer in bacteria. ENDAMR Marie Curie doctoral network (endamr.eu) - an amazing opportunity to work with top scientists in the field all around Europe!
www.cmfi.uni-tuebingen.de/mariecuriephd
www.cmfi.uni-tuebingen.de/mariecuriephd
Reposted by Sebastian Bruchmann
We’ve just released a public Pathogenwatch collection of the MRSN Diversity Panel comprising 100 diverse K. pneumoniae clinical isolates: pathogen.watch/collection/8... #KlebClub
Pathogenwatch
A global platform for genomic surveillance.
pathogen.watch
February 12, 2025 at 10:08 AM
We’ve just released a public Pathogenwatch collection of the MRSN Diversity Panel comprising 100 diverse K. pneumoniae clinical isolates: pathogen.watch/collection/8... #KlebClub
Reposted by Sebastian Bruchmann
🚨 Job alert 🚨 — are you interested in understanding how mobile genetic elements and defence systems shape bacterial genome evolution? 🧬 🧪 🧫 🦠 2x 5-year research positions available in experimental evolution @mermanchester.bsky.social Join us! #microsky
www.jobs.manchester.ac.uk/Job/JobDetai...
www.jobs.manchester.ac.uk/Job/JobDetai...
Research Associate in Experimental Evolution:Manchester
www.jobs.manchester.ac.uk
February 6, 2025 at 9:15 AM
🚨 Job alert 🚨 — are you interested in understanding how mobile genetic elements and defence systems shape bacterial genome evolution? 🧬 🧪 🧫 🦠 2x 5-year research positions available in experimental evolution @mermanchester.bsky.social Join us! #microsky
www.jobs.manchester.ac.uk/Job/JobDetai...
www.jobs.manchester.ac.uk/Job/JobDetai...
Reposted by Sebastian Bruchmann
✨ Excited to share our work in the Journal of Extracellular Vesicles! ✨ We reveal a new family of virulence factors in gram-negative bacteria like P. aeruginosa that drive harmful OMV production. 🦠
isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
Uncovering a new family of conserved virulence factors that promote the production of host‐damaging outer membrane vesicles in gram‐negative bacteria
CprA is a short-chain dehydrogenase/reductase (SDR) that contributes to resistance against colistin and antimicrobial peptides. The cprA gene is conserved across Pseudomonas aeruginosa clades and its....
isevjournals.onlinelibrary.wiley.com
January 22, 2025 at 8:35 PM
✨ Excited to share our work in the Journal of Extracellular Vesicles! ✨ We reveal a new family of virulence factors in gram-negative bacteria like P. aeruginosa that drive harmful OMV production. 🦠
isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Sebastian Bruchmann
Sie suchen #Infektionsforscherinnen? Wir haben ein #StarterPack mit allen Infect-Net-Wissenschaftlerinnen auf BlueSky zusammengestellt:
🇬🇧 Curious about contributions of women in #infection research? We put together a StarterPack with all our Infect-Net experts on BlueSky 🦋
👉 go.bsky.app/JU8KaeQ
🇬🇧 Curious about contributions of women in #infection research? We put together a StarterPack with all our Infect-Net experts on BlueSky 🦋
👉 go.bsky.app/JU8KaeQ
January 24, 2025 at 10:08 AM
Sie suchen #Infektionsforscherinnen? Wir haben ein #StarterPack mit allen Infect-Net-Wissenschaftlerinnen auf BlueSky zusammengestellt:
🇬🇧 Curious about contributions of women in #infection research? We put together a StarterPack with all our Infect-Net experts on BlueSky 🦋
👉 go.bsky.app/JU8KaeQ
🇬🇧 Curious about contributions of women in #infection research? We put together a StarterPack with all our Infect-Net experts on BlueSky 🦋
👉 go.bsky.app/JU8KaeQ
Great collection of papers on adaptive evolution of AMR
Writing lecture slides on 'evolution of AMR' - what are your favourite experimental evolution papers?
Bonus points if not E. coli. #microsky
Bonus points if not E. coli. #microsky
January 15, 2025 at 2:43 PM
Great collection of papers on adaptive evolution of AMR
Reposted by Sebastian Bruchmann
Don't know who to follow for the best in microbial bioinformatics?
This is the Starter Pack you need!
bsky.app/starter-pack...
This is the Starter Pack you need!
bsky.app/starter-pack...
January 13, 2025 at 3:08 AM
Don't know who to follow for the best in microbial bioinformatics?
This is the Starter Pack you need!
bsky.app/starter-pack...
This is the Starter Pack you need!
bsky.app/starter-pack...
Reposted by Sebastian Bruchmann
Application review for the 2025 Gordon Research Conference on Microbial Population Biology begins on Jan 20. Maximize your chance of acceptance and $ support by submitting your application with a poster abstract before that date! Details: www.grc.org/microbial-po...
January 9, 2025 at 10:49 PM
Application review for the 2025 Gordon Research Conference on Microbial Population Biology begins on Jan 20. Maximize your chance of acceptance and $ support by submitting your application with a poster abstract before that date! Details: www.grc.org/microbial-po...
Reposted by Sebastian Bruchmann
I'm putting together a Microbial Bioinformatics starter pack to help get everyone connected in our community. Let me know if there are any bluesky users to be added and share so that twitter refugees can tune back in to the fantastic world microbes go.bsky.app/3ezLo7e
January 10, 2025 at 9:38 AM
I'm putting together a Microbial Bioinformatics starter pack to help get everyone connected in our community. Let me know if there are any bluesky users to be added and share so that twitter refugees can tune back in to the fantastic world microbes go.bsky.app/3ezLo7e
Reposted by Sebastian Bruchmann
Join us for a new season of #KlebCkub! @klebclub.bsky.social
New speakers & new research!
Registration is FREE but mandatory.
Abstracts due by February 16!
Please share !
Link below👇🏻👇🏻
New speakers & new research!
Registration is FREE but mandatory.
Abstracts due by February 16!
Please share !
Link below👇🏻👇🏻
It's that time of year! Registration and abstract submission for the 6th Klebsiella Seminar Series is now open. Participation is free and abstracts are due by February 16th. See the link below for details, and reach out to the organizers with any questions:
forms.gle/gxbvaC6FjzuS...
#KlebClub
forms.gle/gxbvaC6FjzuS...
#KlebClub
Klebsiella Seminar Series 2025
This form can be used to register only or register+submit an abstract for the 2025 Klebsiella Seminar Series. By registering, you will receive a Zoom Webinar link for attendance prior to the event. Re...
forms.gle
January 9, 2025 at 6:18 AM
Join us for a new season of #KlebCkub! @klebclub.bsky.social
New speakers & new research!
Registration is FREE but mandatory.
Abstracts due by February 16!
Please share !
Link below👇🏻👇🏻
New speakers & new research!
Registration is FREE but mandatory.
Abstracts due by February 16!
Please share !
Link below👇🏻👇🏻
Reposted by Sebastian Bruchmann
It’s official: The Microbiology Society is on Bluesky!
January 8, 2025 at 12:03 PM
It’s official: The Microbiology Society is on Bluesky!
Reposted by Sebastian Bruchmann
Letter sent in to the Editor of the Guardian on brain microbiome nonsense.
December 3, 2024 at 10:01 AM
Letter sent in to the Editor of the Guardian on brain microbiome nonsense.