Diego García González
@diegoconcalma.bsky.social
Developmental neurobiologist.
Neurogenesis, neurodevelopmental disorders & evolution.
Group leader in a hotel named IBIS. I'm serious.
https://neurogenesis-lab.org/
Neurogenesis, neurodevelopmental disorders & evolution.
Group leader in a hotel named IBIS. I'm serious.
https://neurogenesis-lab.org/
Reposted by Diego García González
If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle rather than an afterthought, writes @suthanalab.bsky.social.
#neuroskyence
www.thetransmitter.org/animal-model...
#neuroskyence
www.thetransmitter.org/animal-model...
Neuroscience has a species problem
If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle.
www.thetransmitter.org
February 16, 2026 at 8:57 PM
If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle rather than an afterthought, writes @suthanalab.bsky.social.
#neuroskyence
www.thetransmitter.org/animal-model...
#neuroskyence
www.thetransmitter.org/animal-model...
Reposted by Diego García González
𝗨𝗻𝗱𝗲𝗿𝘀𝘁𝗮𝗻𝗱𝗶𝗻𝗴 𝗰𝗼𝗿𝘁𝗶𝗰𝗮𝗹 𝗲𝘃𝗼𝗹𝘂𝘁𝗶𝗼𝗻 sounds straightforward:
compare species, identify differences, explain them.
In reality, it 𝗶𝘀 𝗼𝗻𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗵𝗮𝗿𝗱𝗲𝘀𝘁 𝗽𝗿𝗼𝗯𝗹𝗲𝗺𝘀 𝗶𝗻 𝗻𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲.
𝘞𝘩𝘺?
#CorticalEvolution2026
compare species, identify differences, explain them.
In reality, it 𝗶𝘀 𝗼𝗻𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗵𝗮𝗿𝗱𝗲𝘀𝘁 𝗽𝗿𝗼𝗯𝗹𝗲𝗺𝘀 𝗶𝗻 𝗻𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲.
𝘞𝘩𝘺?
#CorticalEvolution2026
February 12, 2026 at 10:44 AM
𝗨𝗻𝗱𝗲𝗿𝘀𝘁𝗮𝗻𝗱𝗶𝗻𝗴 𝗰𝗼𝗿𝘁𝗶𝗰𝗮𝗹 𝗲𝘃𝗼𝗹𝘂𝘁𝗶𝗼𝗻 sounds straightforward:
compare species, identify differences, explain them.
In reality, it 𝗶𝘀 𝗼𝗻𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗵𝗮𝗿𝗱𝗲𝘀𝘁 𝗽𝗿𝗼𝗯𝗹𝗲𝗺𝘀 𝗶𝗻 𝗻𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲.
𝘞𝘩𝘺?
#CorticalEvolution2026
compare species, identify differences, explain them.
In reality, it 𝗶𝘀 𝗼𝗻𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗵𝗮𝗿𝗱𝗲𝘀𝘁 𝗽𝗿𝗼𝗯𝗹𝗲𝗺𝘀 𝗶𝗻 𝗻𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲.
𝘞𝘩𝘺?
#CorticalEvolution2026
Reposted by Diego García González
🧠 Cortical Evolution 2026
📍 Bilbao, Spain | 🗓 June 15–17, 2026
Join us for an international meeting on the evolution, development & organization of the cerebral cortex.
More information coming soon 👀
🔗 www.ventricular.org/corticalevolution26
#CorEvo26
📍 Bilbao, Spain | 🗓 June 15–17, 2026
Join us for an international meeting on the evolution, development & organization of the cerebral cortex.
More information coming soon 👀
🔗 www.ventricular.org/corticalevolution26
#CorEvo26
January 19, 2026 at 8:57 AM
🧠 Cortical Evolution 2026
📍 Bilbao, Spain | 🗓 June 15–17, 2026
Join us for an international meeting on the evolution, development & organization of the cerebral cortex.
More information coming soon 👀
🔗 www.ventricular.org/corticalevolution26
#CorEvo26
📍 Bilbao, Spain | 🗓 June 15–17, 2026
Join us for an international meeting on the evolution, development & organization of the cerebral cortex.
More information coming soon 👀
🔗 www.ventricular.org/corticalevolution26
#CorEvo26
Reposted by Diego García González
2025 was an exceptional year for the Earth's climate
⬆️ Warmest ocean heat content
⬆️ Tied as second warmest surface temps
⬆️ Second warmest troposphere
⬆️ Record high sea level and GHGs
⬇️ Record low winter Arctic ice
New State of the Climate over at Carbon Brief: www.carbonbrief.org/...
⬆️ Warmest ocean heat content
⬆️ Tied as second warmest surface temps
⬆️ Second warmest troposphere
⬆️ Record high sea level and GHGs
⬇️ Record low winter Arctic ice
New State of the Climate over at Carbon Brief: www.carbonbrief.org/...
January 14, 2026 at 2:53 PM
2025 was an exceptional year for the Earth's climate
⬆️ Warmest ocean heat content
⬆️ Tied as second warmest surface temps
⬆️ Second warmest troposphere
⬆️ Record high sea level and GHGs
⬇️ Record low winter Arctic ice
New State of the Climate over at Carbon Brief: www.carbonbrief.org/...
⬆️ Warmest ocean heat content
⬆️ Tied as second warmest surface temps
⬆️ Second warmest troposphere
⬆️ Record high sea level and GHGs
⬇️ Record low winter Arctic ice
New State of the Climate over at Carbon Brief: www.carbonbrief.org/...
Reposted by Diego García González
🎉 Great news! Our paper is now published in @naturecomm
We identify a specific astrocyte ensemble that mediates THC-induced cognitive impairments during adolescence
Huge thanks to our collaborators @marsicanolab @khakhlab @grandeslab
🔗 rdcu.be/eY0Or
@jsromero.bsky.social @crismonteagudo.bsky.social
We identify a specific astrocyte ensemble that mediates THC-induced cognitive impairments during adolescence
Huge thanks to our collaborators @marsicanolab @khakhlab @grandeslab
🔗 rdcu.be/eY0Or
@jsromero.bsky.social @crismonteagudo.bsky.social
January 14, 2026 at 11:40 AM
🎉 Great news! Our paper is now published in @naturecomm
We identify a specific astrocyte ensemble that mediates THC-induced cognitive impairments during adolescence
Huge thanks to our collaborators @marsicanolab @khakhlab @grandeslab
🔗 rdcu.be/eY0Or
@jsromero.bsky.social @crismonteagudo.bsky.social
We identify a specific astrocyte ensemble that mediates THC-induced cognitive impairments during adolescence
Huge thanks to our collaborators @marsicanolab @khakhlab @grandeslab
🔗 rdcu.be/eY0Or
@jsromero.bsky.social @crismonteagudo.bsky.social
Reposted by Diego García González
NEW article by me!
We can now visualize pathogens down to atoms; design vaccines in weeks; manufacture them in microbial factories; engineer them more precise than ever before.
We're living through a golden age of vaccine development, but only if we continue to invest in them.
We can now visualize pathogens down to atoms; design vaccines in weeks; manufacture them in microbial factories; engineer them more precise than ever before.
We're living through a golden age of vaccine development, but only if we continue to invest in them.
The golden age of vaccine development - Works in Progress Magazine
The first vaccine was a lucky accident. Now we can design new vaccines in weeks, atom by atom.
worksinprogress.co
January 7, 2026 at 3:20 PM
NEW article by me!
We can now visualize pathogens down to atoms; design vaccines in weeks; manufacture them in microbial factories; engineer them more precise than ever before.
We're living through a golden age of vaccine development, but only if we continue to invest in them.
We can now visualize pathogens down to atoms; design vaccines in weeks; manufacture them in microbial factories; engineer them more precise than ever before.
We're living through a golden age of vaccine development, but only if we continue to invest in them.
Reposted by Diego García González
A study on 1.7 million people in Hong Kong shows superior hybrid immunity to Covid in people who got vaccinated before infection vs. people who got infected first. "Our findings are a direct rebuttal to arguments for natural immunity," the authors write. doi.org/10.1016/j.va...
Redirecting
doi.org
December 6, 2025 at 5:02 PM
A study on 1.7 million people in Hong Kong shows superior hybrid immunity to Covid in people who got vaccinated before infection vs. people who got infected first. "Our findings are a direct rebuttal to arguments for natural immunity," the authors write. doi.org/10.1016/j.va...
We are looking for a motivated and creative PhD student who wants to investigate neurogenesis and brain development in beautiful Seville. Do you want to join our team?
Please, check lacaixafoundation.org/en/doctoral-... and get in touch!
Please, check lacaixafoundation.org/en/doctoral-... and get in touch!
Doctoral INPhINIT fellowships
Fellowships for researchers of any nationality who wish to pursue a doctorate at a university or research centre in Spain or Portugal.
lacaixafoundation.org
December 4, 2025 at 5:41 PM
We are looking for a motivated and creative PhD student who wants to investigate neurogenesis and brain development in beautiful Seville. Do you want to join our team?
Please, check lacaixafoundation.org/en/doctoral-... and get in touch!
Please, check lacaixafoundation.org/en/doctoral-... and get in touch!
Reposted by Diego García González
How often have you heard that schizophrenia is “80% genetic”?
That number is almost certainly too high because it comes from twin studies that overestimate heritabilty.
Great explainer of this phenomenon👇
#neuroskyence #neuroscience #psychiatry
That number is almost certainly too high because it comes from twin studies that overestimate heritabilty.
Great explainer of this phenomenon👇
#neuroskyence #neuroscience #psychiatry
I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵
The missing heritability question is now (mostly) answered
Not with a bang but with a whimper
theinfinitesimal.substack.com
November 23, 2025 at 11:49 AM
How often have you heard that schizophrenia is “80% genetic”?
That number is almost certainly too high because it comes from twin studies that overestimate heritabilty.
Great explainer of this phenomenon👇
#neuroskyence #neuroscience #psychiatry
That number is almost certainly too high because it comes from twin studies that overestimate heritabilty.
Great explainer of this phenomenon👇
#neuroskyence #neuroscience #psychiatry
Relevant thread II
Today I am starting a weekly post titled "Autism: The Evidence". I hope it helps someone fight the colossal wave of misinformation that is drowning us. Part 1: I heard Autism prevalence has gone up. Is that true? If so why?
November 22, 2025 at 11:23 AM
Relevant thread II
Relevant thread
November 22, 2025 at 11:22 AM
Relevant thread
Reposted by Diego García González
Nature research paper: Rewiring an olfactory circuit by altering cell-surface combinatorial code
go.nature.com/3MbCoZT
go.nature.com/3MbCoZT
Rewiring an olfactory circuit by altering cell-surface combinatorial code - Nature
In Drosophila, changing the expression of a small set of cell-surface proteins in just one type of olfactory neuron rewires its connections almost entirely to a new postsynaptic partner neuron type, altering the fly’s odour response and courtship behaviour.
go.nature.com
November 21, 2025 at 11:12 AM
Nature research paper: Rewiring an olfactory circuit by altering cell-surface combinatorial code
go.nature.com/3MbCoZT
go.nature.com/3MbCoZT
Reposted by Diego García González
Where on earth is the best laboratory to demonstrate the beauty of fluid dynamics?
Actually, it’s not on earth. Here is the story of the soft cell.
And a longer read: www.maths.ox.ac.uk/node/74308
Actually, it’s not on earth. Here is the story of the soft cell.
And a longer read: www.maths.ox.ac.uk/node/74308
November 19, 2025 at 3:40 PM
Where on earth is the best laboratory to demonstrate the beauty of fluid dynamics?
Actually, it’s not on earth. Here is the story of the soft cell.
And a longer read: www.maths.ox.ac.uk/node/74308
Actually, it’s not on earth. Here is the story of the soft cell.
And a longer read: www.maths.ox.ac.uk/node/74308
Reposted by Diego García González
“Among the EU countries, the proportion of female scientists and engineers varied widely in 2023, with the highest shares registered in Denmark (50.8%), Spain (50.0 %,) and Bulgaria (49.1%), Latvia and Ireland (each 49%).”
Fuente: ec.europa.eu/eurostat/web...
Fuente: ec.europa.eu/eurostat/web...
November 15, 2025 at 4:06 PM
“Among the EU countries, the proportion of female scientists and engineers varied widely in 2023, with the highest shares registered in Denmark (50.8%), Spain (50.0 %,) and Bulgaria (49.1%), Latvia and Ireland (each 49%).”
Fuente: ec.europa.eu/eurostat/web...
Fuente: ec.europa.eu/eurostat/web...
Reposted by Diego García González
Our new manuscript, led by Emily Corrigan, examines inhibitory neuron diversity across approximately 160 million years of evolutionary divergence, as part of BRAIN Initiative Cell Atlas Network (BICAN) developing brain atlas package: www.nature.com/articles/s41...
Conservation and alteration of mammalian striatal interneurons - Nature
An analysis of cell-type diversity in brain samples from a variety of mammalian species, both during development and in adult animals, reveals that the TAC3 initial class of striatal interneurons is c...
www.nature.com
November 7, 2025 at 6:06 PM
Our new manuscript, led by Emily Corrigan, examines inhibitory neuron diversity across approximately 160 million years of evolutionary divergence, as part of BRAIN Initiative Cell Atlas Network (BICAN) developing brain atlas package: www.nature.com/articles/s41...
Reposted by Diego García González
New issue of Nature - with NINE studies on #brain #development from the BRAIN Initiative Cell Atlas Network (BICAN) 🧠🧪🔬
An amazing set of resources for all scientists working on the brain!
🧠 Immersive feature:
www.nature.com/immersive/d4...
🧠 Perspective:
www.nature.com/articles/s41...
An amazing set of resources for all scientists working on the brain!
🧠 Immersive feature:
www.nature.com/immersive/d4...
🧠 Perspective:
www.nature.com/articles/s41...
November 5, 2025 at 6:53 PM
New issue of Nature - with NINE studies on #brain #development from the BRAIN Initiative Cell Atlas Network (BICAN) 🧠🧪🔬
An amazing set of resources for all scientists working on the brain!
🧠 Immersive feature:
www.nature.com/immersive/d4...
🧠 Perspective:
www.nature.com/articles/s41...
An amazing set of resources for all scientists working on the brain!
🧠 Immersive feature:
www.nature.com/immersive/d4...
🧠 Perspective:
www.nature.com/articles/s41...
Reposted by Diego García González
Paul Nurse describing the main job of a PI
(From ‘The Thinking Game’, 2024)
(From ‘The Thinking Game’, 2024)
October 31, 2025 at 8:45 AM
Paul Nurse describing the main job of a PI
(From ‘The Thinking Game’, 2024)
(From ‘The Thinking Game’, 2024)
Reposted by Diego García González
🤔 Is motile #cilia dysfunction a cause of #hydrocephalus ?
The answer depends on who you ask and which species you study. 🤔😕🧐
In mice, motile cilia dysfunction almost always leads to hydrocephalus. In humans, however, the link is far less clear. So why the difference?
The answer depends on who you ask and which species you study. 🤔😕🧐
In mice, motile cilia dysfunction almost always leads to hydrocephalus. In humans, however, the link is far less clear. So why the difference?
Exploring Ciliary Mechanisms in the Causation of Hydrocephalus in Humans—Similarities and Differences from Animal Models - Journal of Molecular Neuroscience
Hydrocephalus is a condition defined by excessive cerebrospinal fluid (CSF) relative to the brain volume. Congenital and infantile forms of hydrocephalus are both genetically and physiologically heter...
doi.org
October 30, 2025 at 8:43 PM
🤔 Is motile #cilia dysfunction a cause of #hydrocephalus ?
The answer depends on who you ask and which species you study. 🤔😕🧐
In mice, motile cilia dysfunction almost always leads to hydrocephalus. In humans, however, the link is far less clear. So why the difference?
The answer depends on who you ask and which species you study. 🤔😕🧐
In mice, motile cilia dysfunction almost always leads to hydrocephalus. In humans, however, the link is far less clear. So why the difference?
Reposted by Diego García González
More than two decades have passed since we discovered that rare disruptions of the FOXP2 gene disturb development of proficient speech/language skills. Today we know of multiple FOXP genes that are directly implicated in distinct brain-related conditions with differences in symptoms & severity.🧪 1/n
October 29, 2025 at 5:09 PM
More than two decades have passed since we discovered that rare disruptions of the FOXP2 gene disturb development of proficient speech/language skills. Today we know of multiple FOXP genes that are directly implicated in distinct brain-related conditions with differences in symptoms & severity.🧪 1/n
Reposted by Diego García González
Interested in understanding how new cell types evolve? Consider joining our group for a PhD!
2026 PhD recruitment is now open.
As well as our main PhD recruitment, which is open to all, we are pleased to be offering scholarships for candidates of Black or mixed Black heritage. Learn more and apply on our website:
www.crick.ac.uk/careers-stud...
As well as our main PhD recruitment, which is open to all, we are pleased to be offering scholarships for candidates of Black or mixed Black heritage. Learn more and apply on our website:
www.crick.ac.uk/careers-stud...
PhD student recruitment
PhD recruitment information.
www.crick.ac.uk
October 7, 2025 at 4:43 PM
Interested in understanding how new cell types evolve? Consider joining our group for a PhD!
Reposted by Diego García González
RIP John Gurdon
October 7, 2025 at 6:06 PM
RIP John Gurdon
Reposted by Diego García González
Vertebrate Genome Evolution. Annual Symposium of the @louisjeantetfdn.bsky.social Foundation in Geneva. Free access on site and on line. Great speakers for a super interesting topic. #SvantePaabo #HenrikKaessmann organisers 🙏 See you there! @biology-unige.bsky.social @genevunige.bsky.social
October 3, 2025 at 7:14 AM
Vertebrate Genome Evolution. Annual Symposium of the @louisjeantetfdn.bsky.social Foundation in Geneva. Free access on site and on line. Great speakers for a super interesting topic. #SvantePaabo #HenrikKaessmann organisers 🙏 See you there! @biology-unige.bsky.social @genevunige.bsky.social
Reposted by Diego García González
Reposted by Diego García González
I add that earlier and later diagnosed autism are not valid diagnostic terms and what we are looking at is (one) gradient. Also genetics explains only a fraction of the variance, with most studied factors explaining < 10%. We have FAQs in the Supplementary where we address common questions.
October 1, 2025 at 4:05 PM
I add that earlier and later diagnosed autism are not valid diagnostic terms and what we are looking at is (one) gradient. Also genetics explains only a fraction of the variance, with most studied factors explaining < 10%. We have FAQs in the Supplementary where we address common questions.