Manuel Irimia
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mirimiam.bsky.social
Manuel Irimia
@mirimiam.bsky.social
ICREA Evolutionary Biologist working on transcriptomics of development and evolution at @upf.edu and @crg.eu. Coordinator of the @evomg-bcn.bsky.social Joint Program.

Lab website: http://transdevolab.com
Reposted by Manuel Irimia
#Transfer
UPF’s SPLICE-BETA project receives an ERC Proof of Concept Grant to develop a new treatment targeting the root cause of #Diabetes

Congrats to the team led by @mirimiam.bsky.social & Jonas Juan cc @erc.europa.eu @upf.edu @prbb.org
tuit.cat/7kLHr
UPF’s SPLICE-BETA project receives an ERC Proof of Concept Grant to develop a new treatment targeting the root cause of diabetes
El projecte obté 150.000 euros del Consell Europeu de Recerca per impulsar un possible tractament capaç de restaurar la funció de les cèl·lules del pàncrees encarregades de produir insulina. Un pas en...
tuit.cat
February 3, 2026 at 10:49 AM
Reposted by Manuel Irimia
We are delighted to announce that @mirimiam.bsky.social (@melisupf.bsky.social) has been awarded one Proof of Concept Grant to work on RNA splicing therapeutics for beta cell dysfunction and diabetes.
300 Proof of Concept Grants awarded under the ERC 2025 work programme, with an overall budget of €45 million, following the selection of a further 136 grantees.
👉 erc.europa.eu/news-events/...
January 27, 2026 at 1:40 PM
Reposted by Manuel Irimia
January 25, 2026 at 12:32 PM
Reposted by Manuel Irimia
Reposted by Manuel Irimia
0/10
🥳 our #exocyst paper out in @cp-cell.bsky.social, led by Marta, Sebas & @sasmeek.bsky.social in collab with @jonasries.bsky.social, @cmanzo.bsky.social & Castaño-Díez labs #Quantitative_Cell_Biology

Continuum architecture dynamics of vesicle tethering in exocytosis
www.cell.com/cell/fulltex...
Continuum architecture dynamics of vesicle tethering in exocytosis
Data from complementary imaging techniques were integrated into a model that resolves the dynamic exocyst ensemble and membrane architecture during exocytosis, an essential cellular pathway. Sec18 med...
www.cell.com
January 16, 2026 at 5:28 PM
Reposted by Manuel Irimia
We are looking for a Bioinformatician (both graduate and postdoctoral levels) to join our lab. Please help us spread the word about this opportunity!

Applicants should submit their motivation letter, full CV and academic record to Juan R. Martínez-Morales: jrmarmor@upo.es
January 12, 2026 at 10:35 AM
Reposted by Manuel Irimia
Our work on the evolution of the regulatory genome of echinoderms is now out in @natecoevo.nature.com. Led by my former PhD Marta Magri, Danila Voronov & Saoirse Foley. Great collaboration of Arnone, Hinman & Maeso labs, started long time ago with our missed José Luis Gomez-Skarmeta: rdcu.be/eXX8l
Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes
Nature Ecology & Evolution - Analysis of the 3D chromatin architecture and cis-regulatory elements in a sea urchin and a sea star reveals mechanisms of 3D chromatin organization in echinoderms...
rdcu.be
January 7, 2026 at 7:33 PM
Reposted by Manuel Irimia
Exciting news to start the new year! We’re thrilled to see this work finally out in @natecoevo.nature.com, the result of a major collaboration between my lab and the labs of Veronica Hinman and Nacho Maeso, began many years ago with the dear José Luis Gómez-Skarmeta.
www.nature.com/articles/s41...
January 7, 2026 at 10:17 AM
Reposted by Manuel Irimia
Open Senior Bioinformatician position at
@sangerinstitute.bsky.social
Tree of Life, to work on the Biodiversity Cell Atlas initiative with @marakat.bsky.social and me.

📅 Apply by January 18
🔗 sanger.wd103.myworkdayjobs.com/en-US/Wellco...

Please share with anyone who might be interested!
Senior Bioinformatician - Biodiversity Cell Atlas
Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenge...
sanger.wd103.myworkdayjobs.com
January 2, 2026 at 1:12 PM
🚨🚨🚨

We're looking for a research tech to work on alt splicing, pancreatic islets and diabetes. The goal is to set a high-throughput platform to investigate the role of alternative exons in beta cell biology!

Interested in joining our lab at @melisupf.bsky.social? 👇

www.upf.edu/documents/d/...
www.upf.edu
December 23, 2025 at 12:36 PM
Reposted by Manuel Irimia
Canada is launching a new funding program for PhD students and postdoctoral scientists.

Reach out to me if you are interested in studying gene regulation, RNA splicing and/or cancer immunotherapy using computational and/or experimental approaches.

#PhD #Postdoc
Launch of new Canada Impact+ Research Training Awards
As announced in Budget 2025 -
nserc-crsng.canada.ca
December 19, 2025 at 8:18 PM
Reposted by Manuel Irimia
2️⃣ #InvestigadorsICREA seleccionats a la convocatòria @caixaresearch.bsky.social d'Investigació en Salut.

🔹Maria Macias @maciaslab.bsky.social @irbbarcelona.org
🔹Manuel Irimia @mirimiam.bsky.social @upf.edu

Enhorabona per aquest impuls per a la vostra carrera investigadora. 🚀
short.do/iLiUwr
34 projectes de recerca biomèdica amb potencial impacte social reben 26 milions en ajuts de la Fundació ”la Caixa” | MediaHub de la Fundació "la Caixa"
La convocatòria d'Investigació en Salut 2025 ha seleccionat 34 projectes de recerca biomèdica que han dotat amb un milió d'euros.
mediahub.fundacionlacaixa.org
December 9, 2025 at 8:54 AM
Reposted by Manuel Irimia
📣 Save the date!
On December 12th, The future of ART is now! The 6th symposium Catedra Eugin - @upf.edu will happen at the
@prbb.org

Registration is free - tuit.cat/l7reG
#AssistedReproduction #artificiallntelligence
December 3, 2025 at 9:37 AM
Reposted by Manuel Irimia
Several opportunities to join our group as a PhD candidate with bioinformatics or experimental background and interests in #microbiome, #Candida, or #evolution.

👉 IRB call:
www.irbbarcelona.org/en/careers/y...
👉 Inphinit call:
lacaixafoundation.org/en/doctoral-...
👉 EvoMG call
www.evomg-dn.eu
November 30, 2025 at 11:35 AM
Reposted by Manuel Irimia
We’re excited to introduce @mirimiam.bsky.social (@crg.eu ), one of our EvoMG-DN PIs!

Explore the project and PhD details on our website → www.evomg-dn.eu

#PhD #DoctoralTraining #ResearchCareers #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology #MSCA #HorizonEurope #EUResearch
November 25, 2025 at 1:04 PM
Reposted by Manuel Irimia
1/ 🩸 Diabetes occurs when the beta cells in the pancreas, which produce insulin, don't function or have been destroyed.

With a #Health Research grant ➕ BreakthroughT1D, @mirimiam.bsky.social seeks to improve the beta cells it has created in the lab for use as therapy.

https://tinyurl.com/sdhs5yrp
November 20, 2025 at 10:34 AM
Reposted by Manuel Irimia
Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9
Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes - Nature Genetics
Long-read sequencing in 18 unicellular eukaryotes reveals that 6mA is widespread across eukaryotes and is enriched at transcriptionally permissive regions, which are also marked by H3K4me3.
www.nature.com
November 18, 2025 at 12:00 PM
Reposted by Manuel Irimia
Still looking for our perfect doctoral candidate as part of @evomg-dn.bsky.social - come and join us to work on the evolutionary pressures that shape gene expression and disease in the uterus!

Please RT (or is it RB? not sure how our lingo has changed!)
November 14, 2025 at 10:22 AM
Reposted by Manuel Irimia
Hey, thanks to the @evomg-dn.bsky.social you can join the Developmental and Evolutionary Transcriptomics Laboratory led by Manuel Irimia ( @mirimiam.bsky.social ) with Jonàs Juan as PI to develop your PhD exploring the molecular adaptation of pancreatic islets. 🧬🦇

#PhDOffer #AcademicJobs @crg.eu
Meet our EvoMG-DN PI, Jonas Juan-Mateu from @melisupf.bsky.social -Barcelona

Interested in joining the network? Find out more about the PhD programme → www.evomg-dn.eu

#PhD #DoctoralTraining #ResearchCareers #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology #MSCA #HorizonEurope
November 14, 2025 at 10:22 AM
Reposted by Manuel Irimia
Meet our EvoMG-DN PI, Jonas Juan-Mateu from @melisupf.bsky.social -Barcelona

Interested in joining the network? Find out more about the PhD programme → www.evomg-dn.eu

#PhD #DoctoralTraining #ResearchCareers #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology #MSCA #HorizonEurope
November 13, 2025 at 12:43 PM
Reposted by Manuel Irimia
November 14, 2025 at 10:19 AM
Reposted by Manuel Irimia
Today we had a great EvoMG Seminar by Dario Valenzano @dvalenzano.bsky.social from FLI, who told us about some of their recent aging work using the fascinating short-lived killifish.

Hosted by @mirimiam.bsky.social

evomedgenomics.com/events/exter...
November 5, 2025 at 11:18 PM
Reposted by Manuel Irimia
1. Map evolutionary diversity to hack biomedical innovation
2. Revolutionize cancer therapy
3. Target the development of antimicrobial resistance
4. Address Anthropocene-related diseases
5. Support healthier behaviors
6. Improve pandemic responses
by Barbara Natterson-Horowitz & Dan Blumstein!
6 ways evolutionary medicine can transform our health
Evolutionary medicine is an emerging interdisciplinary field with huge potential to improve human health and tackle a broad scope of major health challenges.
www.weforum.org
November 4, 2025 at 5:03 PM