Silvia De Rubeis
@derubeislab.bsky.social
Neuroscientist & geneticist studying neurodevelopment, autism, and DDX3X | Immigrant | 2x mom | #firstgen | #Humboldtian (she/her)
Born and raised in 🇮🇹, had fun in 🇧🇪, transplanted in 🇺🇸
Views my own
https://labs.icahn.mssm.edu/derubeislab/
Born and raised in 🇮🇹, had fun in 🇧🇪, transplanted in 🇺🇸
Views my own
https://labs.icahn.mssm.edu/derubeislab/
Pinned
Silvia De Rubeis
@derubeislab.bsky.social
· May 18
Sex-specific perturbations of neuronal development caused by mutations in the autism risk gene DDX3X - Nature Communications
Genetic mutations in the DDX3X gene are associated with a neurodevelopmental disorder primarily affecting females. Here authors show that Ddx3x mediates sexual dimorphisms during brain development at ...
www.nature.com
🧪 New paper alert!
In new work led by Adele Mossa out now in @natcomms.nature.com, we find that the #autism risk gene #DDX3X is a critical regulator of sexual dimorphisms in neuronal neurodevelopment 🧬 🧠
www.nature.com/articles/s41...
In new work led by Adele Mossa out now in @natcomms.nature.com, we find that the #autism risk gene #DDX3X is a critical regulator of sexual dimorphisms in neuronal neurodevelopment 🧬 🧠
www.nature.com/articles/s41...
Reposted by Silvia De Rubeis
I'm looking to hire a postgraduate research associate in Computational Psychiatry for my new lab at Yale. Please see link below for details & help RT 🙏
postdocs.yale.edu/posts/2026-0...
postdocs.yale.edu/posts/2026-0...
Postgraduate Associate Position in Computational Psychiatry — Department of Psychiatry, School of Medicine
postdocs.yale.edu
January 13, 2026 at 1:49 PM
I'm looking to hire a postgraduate research associate in Computational Psychiatry for my new lab at Yale. Please see link below for details & help RT 🙏
postdocs.yale.edu/posts/2026-0...
postdocs.yale.edu/posts/2026-0...
Reposted by Silvia De Rubeis
Announcing the 2026 edition of the EMBO workshop on RNA localization and local translation! This meeting will be held June 30 - July 4 near Porto, Portugal. Come for exciting updates in the field from both established investigators and trainees. See the link below for details!
December 8, 2025 at 4:40 PM
Announcing the 2026 edition of the EMBO workshop on RNA localization and local translation! This meeting will be held June 30 - July 4 near Porto, Portugal. Come for exciting updates in the field from both established investigators and trainees. See the link below for details!
We are thrilled (and not nervous at all 🤪) to announce that our very own Lauren Dierdorff 💫 will defend her PhD on Dec 10!
Lauren’s research examines the circuits underlying motor deficits in #DDX3X syndrome 🧠
Go Lauren!🍀💪
Lauren’s research examines the circuits underlying motor deficits in #DDX3X syndrome 🧠
Go Lauren!🍀💪
December 6, 2025 at 8:21 PM
We are thrilled (and not nervous at all 🤪) to announce that our very own Lauren Dierdorff 💫 will defend her PhD on Dec 10!
Lauren’s research examines the circuits underlying motor deficits in #DDX3X syndrome 🧠
Go Lauren!🍀💪
Lauren’s research examines the circuits underlying motor deficits in #DDX3X syndrome 🧠
Go Lauren!🍀💪
So excited about the 2026 DDX3X International Conference in Genova, Italy🐬
Looking forward to meet many #DDX3X families and share our research!
Stay tuned for the program!
@ddx3x-es.bsky.social
#raredisease
@sinaibrain.bsky.social
Looking forward to meet many #DDX3X families and share our research!
Stay tuned for the program!
@ddx3x-es.bsky.social
#raredisease
@sinaibrain.bsky.social
December 6, 2025 at 8:03 PM
So excited about the 2026 DDX3X International Conference in Genova, Italy🐬
Looking forward to meet many #DDX3X families and share our research!
Stay tuned for the program!
@ddx3x-es.bsky.social
#raredisease
@sinaibrain.bsky.social
Looking forward to meet many #DDX3X families and share our research!
Stay tuned for the program!
@ddx3x-es.bsky.social
#raredisease
@sinaibrain.bsky.social
Reposted by Silvia De Rubeis
Apply! It's a great experience and you get to meet very cool people. Let me know if you want to know more 🧪
Apply for our Pathway to Independence (PI) programme, supporting postdocs in #devbio and #stemcell research during the transition to their first group leader position: www.biologists.com/grants/devel...
Application deadline: 2 February 2026.
Application deadline: 2 February 2026.
December 2, 2025 at 6:02 PM
Apply! It's a great experience and you get to meet very cool people. Let me know if you want to know more 🧪
Reposted by Silvia De Rubeis
NIH Study Sections are on hold...again. drugmonkey.wordpress.com/2025/10/13/n...
NIH Study Sections are on hold…again.
The primary input to deciding on the merit of proposals submitted to the NIH for potential funding, as most of my remaining blog audience well knows, is the outcome of the initial peer-review proce…
drugmonkey.wordpress.com
October 13, 2025 at 9:20 PM
NIH Study Sections are on hold...again. drugmonkey.wordpress.com/2025/10/13/n...
Reposted by Silvia De Rubeis
Last year, we helped 100 students save $31K in grad school app fees, giving students from underserved communities the freedom to apply widely.
This year we lost 16 partners = $8.2K setback = 110 fewer dreams.
🎓 You can change that.
💸 Donate to open 110 new doors.
givebutter.com/supportCL
This year we lost 16 partners = $8.2K setback = 110 fewer dreams.
🎓 You can change that.
💸 Donate to open 110 new doors.
givebutter.com/supportCL
October 13, 2025 at 7:17 PM
Last year, we helped 100 students save $31K in grad school app fees, giving students from underserved communities the freedom to apply widely.
This year we lost 16 partners = $8.2K setback = 110 fewer dreams.
🎓 You can change that.
💸 Donate to open 110 new doors.
givebutter.com/supportCL
This year we lost 16 partners = $8.2K setback = 110 fewer dreams.
🎓 You can change that.
💸 Donate to open 110 new doors.
givebutter.com/supportCL
Reposted by Silvia De Rubeis
DDX3X can cause a neurodevelopmental disorder in males. 🧬
📢 A new cohort of affected males broadens the spectrum. ⬇️
www.nature.com/articles/s41...
📢 A new cohort of affected males broadens the spectrum. ⬇️
www.nature.com/articles/s41...
DDX3X-related neurodevelopmental disorder in males – presenting a new cohort of 19 males and a literature review - European Journal of Human Genetics
European Journal of Human Genetics - DDX3X-related neurodevelopmental disorder in males – presenting a new cohort of 19 males and a literature review
www.nature.com
August 26, 2025 at 10:25 AM
DDX3X can cause a neurodevelopmental disorder in males. 🧬
📢 A new cohort of affected males broadens the spectrum. ⬇️
www.nature.com/articles/s41...
📢 A new cohort of affected males broadens the spectrum. ⬇️
www.nature.com/articles/s41...
Reposted by Silvia De Rubeis
✨ Applying for fellowships?
Check out 40+ successful sample applications from:
NSF-GRFP, PD Soros, HHMI Gilliam, Ford, NIH F31 …and more!
Get inspired and strengthen your own application by learning from winners in your field.
🔗 cientificolatino.com/writing-center
Check out 40+ successful sample applications from:
NSF-GRFP, PD Soros, HHMI Gilliam, Ford, NIH F31 …and more!
Get inspired and strengthen your own application by learning from winners in your field.
🔗 cientificolatino.com/writing-center
September 2, 2025 at 4:47 PM
✨ Applying for fellowships?
Check out 40+ successful sample applications from:
NSF-GRFP, PD Soros, HHMI Gilliam, Ford, NIH F31 …and more!
Get inspired and strengthen your own application by learning from winners in your field.
🔗 cientificolatino.com/writing-center
Check out 40+ successful sample applications from:
NSF-GRFP, PD Soros, HHMI Gilliam, Ford, NIH F31 …and more!
Get inspired and strengthen your own application by learning from winners in your field.
🔗 cientificolatino.com/writing-center
Reposted by Silvia De Rubeis
“How does a brain take shape?” Neurobiologist @bassemh.bsky.social on the embryonic cells that fold into the neural tube and become the brain.
Discover more in The Brain’s Secret.
#Biology #Neuroscience #Brain #Education #ReliableKnowledge #PublicEngagement
Discover more in The Brain’s Secret.
#Biology #Neuroscience #Brain #Education #ReliableKnowledge #PublicEngagement
August 26, 2025 at 2:05 PM
“How does a brain take shape?” Neurobiologist @bassemh.bsky.social on the embryonic cells that fold into the neural tube and become the brain.
Discover more in The Brain’s Secret.
#Biology #Neuroscience #Brain #Education #ReliableKnowledge #PublicEngagement
Discover more in The Brain’s Secret.
#Biology #Neuroscience #Brain #Education #ReliableKnowledge #PublicEngagement
Reposted by Silvia De Rubeis
HAPPENING NOW! Visit the Icahn School of medicine #SURP4US Poster Session as @wellesley.edu's Kayla Quinlan, mentored by the DeRubeis Lab, presents her summer research project on “Characterizing olfactory bulb development in a mouse model of DDX3X syndrome”. @mountsinainyc.bsky.social NOT TO MISS!
August 8, 2025 at 5:02 PM
HAPPENING NOW! Visit the Icahn School of medicine #SURP4US Poster Session as @wellesley.edu's Kayla Quinlan, mentored by the DeRubeis Lab, presents her summer research project on “Characterizing olfactory bulb development in a mouse model of DDX3X syndrome”. @mountsinainyc.bsky.social NOT TO MISS!
Reposted by Silvia De Rubeis
To all post-docs: The Genome Biology dept @embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Group Leader - Genome Biology Unit
Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...
embl.wd103.myworkdayjobs.com
July 30, 2025 at 1:41 PM
To all post-docs: The Genome Biology dept @embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Reposted by Silvia De Rubeis
🎉 Big congratulations to GSMI-NYC 2022 scholar, @michae1flores.bsky.social, on being awarded the prestigious HHMI Gilliam Fellowship! 🌟 We are so proud of you leading the way for the next generation of scientists!
August 11, 2025 at 8:25 PM
🎉 Big congratulations to GSMI-NYC 2022 scholar, @michae1flores.bsky.social, on being awarded the prestigious HHMI Gilliam Fellowship! 🌟 We are so proud of you leading the way for the next generation of scientists!
Reposted by Silvia De Rubeis
A reminder that the mRNA vaccine technology saved millions of lives during the Covid pandemic and received the 2023 Nobel Prize for Medicine
August 10, 2025 at 12:26 AM
A reminder that the mRNA vaccine technology saved millions of lives during the Covid pandemic and received the 2023 Nobel Prize for Medicine
Incredibly proud to see our alumnus Michael Flores among the 2025 Gilliam Fellows 🥹
Congratulations to Michael and all other Fellows!
Congratulations to Michael and all other Fellows!
Congratulations 2025 Gilliam Fellows and Advisors! 🎉
The Gilliam Fellows Program launches promising PhD students into impactful scientific research careers while fostering inclusive training environments.
Through this program, HHMI supports both graduate students and their faculty thesis advisors.
The Gilliam Fellows Program launches promising PhD students into impactful scientific research careers while fostering inclusive training environments.
Through this program, HHMI supports both graduate students and their faculty thesis advisors.
August 7, 2025 at 1:49 PM
Incredibly proud to see our alumnus Michael Flores among the 2025 Gilliam Fellows 🥹
Congratulations to Michael and all other Fellows!
Congratulations to Michael and all other Fellows!
Reposted by Silvia De Rubeis
Reposted by Silvia De Rubeis
Today, SfN joins communities across the nation in celebrating #Juneteenth — a day that honors freedom, resilience, and progress.
We celebrate the remarkable contributions of Black neuroscientists whose research has expanded our understanding of the brain and improved lives worldwide.
#neurosky
We celebrate the remarkable contributions of Black neuroscientists whose research has expanded our understanding of the brain and improved lives worldwide.
#neurosky
June 19, 2025 at 12:27 PM
Today, SfN joins communities across the nation in celebrating #Juneteenth — a day that honors freedom, resilience, and progress.
We celebrate the remarkable contributions of Black neuroscientists whose research has expanded our understanding of the brain and improved lives worldwide.
#neurosky
We celebrate the remarkable contributions of Black neuroscientists whose research has expanded our understanding of the brain and improved lives worldwide.
#neurosky
Reposted by Silvia De Rubeis
What? Some good news on a Friday?
Parent Fellowship Notices of Funding Opportunities are up!
F30, F31, F32, F33
grants.nih.gov/grants/guide...
Parent Fellowship Notices of Funding Opportunities are up!
F30, F31, F32, F33
grants.nih.gov/grants/guide...
PA-25-422: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) PA-25-422. NI...
grants.nih.gov
June 13, 2025 at 11:06 PM
What? Some good news on a Friday?
Parent Fellowship Notices of Funding Opportunities are up!
F30, F31, F32, F33
grants.nih.gov/grants/guide...
Parent Fellowship Notices of Funding Opportunities are up!
F30, F31, F32, F33
grants.nih.gov/grants/guide...
Reposted by Silvia De Rubeis
Today is DDX3X Awareness Day!
12th June marks the fifth annual International DDX3X Day!
Share our expert-written guide, freely available online at bit.ly/3VlQ0D5
#DDX3X #RareChromo #GeneDisorder #ChromosomeX #AwarenessDay #Unique #FamilySupport
12th June marks the fifth annual International DDX3X Day!
Share our expert-written guide, freely available online at bit.ly/3VlQ0D5
#DDX3X #RareChromo #GeneDisorder #ChromosomeX #AwarenessDay #Unique #FamilySupport
June 12, 2025 at 11:22 AM
Today is DDX3X Awareness Day!
12th June marks the fifth annual International DDX3X Day!
Share our expert-written guide, freely available online at bit.ly/3VlQ0D5
#DDX3X #RareChromo #GeneDisorder #ChromosomeX #AwarenessDay #Unique #FamilySupport
12th June marks the fifth annual International DDX3X Day!
Share our expert-written guide, freely available online at bit.ly/3VlQ0D5
#DDX3X #RareChromo #GeneDisorder #ChromosomeX #AwarenessDay #Unique #FamilySupport
Reposted by Silvia De Rubeis
the reissued NOFO for theRuth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) is finally published! grants.nih.gov/grants/guide...
PA-25-425: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Par...
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without N...
grants.nih.gov
June 13, 2025 at 6:23 PM
the reissued NOFO for theRuth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) is finally published! grants.nih.gov/grants/guide...
Reposted by Silvia De Rubeis
Padilla: If this is how DHS responds to a senator with a question you can only imagine what they're doing to farm workers, to cooks, to day laborers out in the Los Angeles community and throughout California.
June 12, 2025 at 7:33 PM
Padilla: If this is how DHS responds to a senator with a question you can only imagine what they're doing to farm workers, to cooks, to day laborers out in the Los Angeles community and throughout California.
Reposted by Silvia De Rubeis
"Tanner, a chemist at the Univ. of Mississippi working to develop a novel approach for treating glioblastoma, was notified in April that the grant was terminated.
“I would like to cure brain cancer,” Dr. Tanner said. “I think that's not particularly controversial.”
www.nytimes.com/interactive/...
“I would like to cure brain cancer,” Dr. Tanner said. “I think that's not particularly controversial.”
www.nytimes.com/interactive/...
The Gutting of America’s Medical Research: Here Is Every Canceled or Delayed N.I.H. Grant
Some cuts have been starkly visible, but the country’s medical grant-making machinery has also radically transformed outside the public eye.
www.nytimes.com
June 8, 2025 at 6:12 PM
"Tanner, a chemist at the Univ. of Mississippi working to develop a novel approach for treating glioblastoma, was notified in April that the grant was terminated.
“I would like to cure brain cancer,” Dr. Tanner said. “I think that's not particularly controversial.”
www.nytimes.com/interactive/...
“I would like to cure brain cancer,” Dr. Tanner said. “I think that's not particularly controversial.”
www.nytimes.com/interactive/...
Reposted by Silvia De Rubeis
NEW STUDY from Adele Mossa, Lauren Dierdorff, Jeronimo Lukin, Silvia De Rubeis, et al. unveils sex-specific molecular signatures when Ddx3x is missing, impacting the neuronal proteome, protein synthesis machinery & nucleoli structure. Learn More @natcomms.nature.com 👉 www.nature.com/articles/s41...
June 2, 2025 at 12:00 AM
NEW STUDY from Adele Mossa, Lauren Dierdorff, Jeronimo Lukin, Silvia De Rubeis, et al. unveils sex-specific molecular signatures when Ddx3x is missing, impacting the neuronal proteome, protein synthesis machinery & nucleoli structure. Learn More @natcomms.nature.com 👉 www.nature.com/articles/s41...