Delaney Sullivan
@delaneyksull.bsky.social
UCLA-Caltech MD/PhD student
Stanford ‘16
Stanford ‘16
Reposted by Delaney Sullivan
Super excited to get this out. This collab started a few years ago and is the first paper from it. Here, with experimental and computational approaches we:
1. establish that cell villages can be just as accurate (one might argue more accurate!) than arrayed-based designs
bsky.app/profile/bior...
1. establish that cell villages can be just as accurate (one might argue more accurate!) than arrayed-based designs
bsky.app/profile/bior...
Cell villages and Dirichlet modeling map human cell fitness genetics https://www.biorxiv.org/content/10.1101/2025.09.26.678880v1
September 29, 2025 at 4:47 PM
Super excited to get this out. This collab started a few years ago and is the first paper from it. Here, with experimental and computational approaches we:
1. establish that cell villages can be just as accurate (one might argue more accurate!) than arrayed-based designs
bsky.app/profile/bior...
1. establish that cell villages can be just as accurate (one might argue more accurate!) than arrayed-based designs
bsky.app/profile/bior...
Reposted by Delaney Sullivan
Super excited to have this out. Thanks very much to the reviewers who helped improve this manuscript. Congrats to @jingyour.bsky.social!
bsky.app/profile/bioi...
bsky.app/profile/bioi...
🧩 Recently published in Bioinformatics Advances: “Rosace-AA: Enhancing interpretation of deep mutational scanning data with amino acid substitution and position-specific insights”
Full article available: https://doi.org/10.1093/bioadv/vbaf218
Full article available: https://doi.org/10.1093/bioadv/vbaf218
September 22, 2025 at 5:35 PM
Super excited to have this out. Thanks very much to the reviewers who helped improve this manuscript. Congrats to @jingyour.bsky.social!
bsky.app/profile/bioi...
bsky.app/profile/bioi...
Reposted by Delaney Sullivan
Happy to see the ENCODE4 long-read RNA tracks now up on UCSC! Thank you to Jeltje, Mark, and any others at UCSC for working to make this happen 🤩
👉 Read the preprint: www.biorxiv.org/content/10.1...
👉 Read the preprint: www.biorxiv.org/content/10.1...
July 18, 2025 at 12:06 PM
Happy to see the ENCODE4 long-read RNA tracks now up on UCSC! Thank you to Jeltje, Mark, and any others at UCSC for working to make this happen 🤩
👉 Read the preprint: www.biorxiv.org/content/10.1...
👉 Read the preprint: www.biorxiv.org/content/10.1...
Reposted by Delaney Sullivan
Suspension of all grants to UCLA www.latimes.com/california/s...
Trump freezes $200 million in UCLA science and medical research funding, citing antisemitism
The Trump administration has frozen roughly $200 million in National Science Foundation, National Institutes of Health and other federal agency-funded research at UCLA, citing allegations the school d...
www.latimes.com
August 1, 2025 at 4:27 AM
Suspension of all grants to UCLA www.latimes.com/california/s...
Reposted by Delaney Sullivan
Many proteins bind RNA, yet we still don’t know what RNAs most bind because methods map one RBP at a time. In @cp-cell.bsky.social, with the Jovanovic lab, we describe SPIDR – a method for mapping the RNA binding sites of dozens of RBPs in a single experiment. www.sciencedirect.com/science/arti...
July 26, 2025 at 7:15 PM
Many proteins bind RNA, yet we still don’t know what RNAs most bind because methods map one RBP at a time. In @cp-cell.bsky.social, with the Jovanovic lab, we describe SPIDR – a method for mapping the RNA binding sites of dozens of RBPs in a single experiment. www.sciencedirect.com/science/arti...
Reposted by Delaney Sullivan
Super proud of my first student, @jingyour.bsky.social! Well done! Looking forward to the amazing work you will do in the future 🥲 bsky.app/profile/jing...
Thrilled to share that I just successfully defended my PhD! Thanks to my committee, collaborators, and everyone who’d supported me throughout my seven years at UCLA. A special thank you to my PI Harold for his incredible mentorship! @hjp.bsky.social
July 21, 2025 at 11:15 PM
Super proud of my first student, @jingyour.bsky.social! Well done! Looking forward to the amazing work you will do in the future 🥲 bsky.app/profile/jing...
Reposted by Delaney Sullivan
Nature research paper: Mapping and engineering RNA-driven architecture of the multiphase nucleolus
https://go.nature.com/44Tib11
https://go.nature.com/44Tib11
Mapping and engineering RNA-driven architecture of the multiphase nucleolus - Nature
Spatially segregated rRNA processing dictates nucleolar morphology and drives outward progression of pre-ribosomal RNA through nucleolar phases.
go.nature.com
July 8, 2025 at 8:41 PM
Nature research paper: Mapping and engineering RNA-driven architecture of the multiphase nucleolus
https://go.nature.com/44Tib11
https://go.nature.com/44Tib11
Reposted by Delaney Sullivan
I wrote a review of a recent paper on false discovery and multiple testing correction. liorpachter.wordpress.com/2025/06/16/r...
Reply to: Reply to: False positives in the study of memory-related gene expression
In the Nature paper “Spatial transcriptomics reveal neuron–astrocyte synergy in long-term memory” published on March 14th, 2024, authors Sun et al. claimed to identify cell-type specifi…
liorpachter.wordpress.com
June 16, 2025 at 9:31 PM
I wrote a review of a recent paper on false discovery and multiple testing correction. liorpachter.wordpress.com/2025/06/16/r...
Reposted by Delaney Sullivan
Congratulations to Anne Kil on successful defense of her PhD! Her thesis focused on engineering solutions for saliva as a biomedical diagnostic, from improved collection asmedigitalcollection.asme.org/medicaldevic... to assessing the potential of saliva multiomics www.biorxiv.org/content/10.1...
May 4, 2025 at 11:56 PM
Congratulations to Anne Kil on successful defense of her PhD! Her thesis focused on engineering solutions for saliva as a biomedical diagnostic, from improved collection asmedigitalcollection.asme.org/medicaldevic... to assessing the potential of saliva multiomics www.biorxiv.org/content/10.1...
Reposted by Delaney Sullivan
Congratulations to @delaneyksull.bsky.social on successfully defending his PhD (photo below with his committee: Barbara Wold, @mitchguttman.bsky.social, and another of my former students @hjp.bsky.social).
His thesis is on software, tools, and methods development for single-cell transcriptomics.
His thesis is on software, tools, and methods development for single-cell transcriptomics.
May 5, 2025 at 12:14 AM
Congratulations to @delaneyksull.bsky.social on successfully defending his PhD (photo below with his committee: Barbara Wold, @mitchguttman.bsky.social, and another of my former students @hjp.bsky.social).
His thesis is on software, tools, and methods development for single-cell transcriptomics.
His thesis is on software, tools, and methods development for single-cell transcriptomics.
Reposted by Delaney Sullivan
Very excited to finally see this out! 🦠🧬
Huge thanks to all of my amazing co-authors! @lpachter.bsky.social @delaneyksull.bsky.social
Original paper thread: x.com/neuroluebber...
Free access link to the paper: rdcu.be/eiIWC
Huge thanks to all of my amazing co-authors! @lpachter.bsky.social @delaneyksull.bsky.social
Original paper thread: x.com/neuroluebber...
Free access link to the paper: rdcu.be/eiIWC
Detection of viral sequences at single-cell resolution identifies novel viruses associated with host gene expression changes - @lauraluebbert.com @lpachter.bsky.social go.nature.com/4lGrSY3
Detection of viral sequences at single-cell resolution identifies novel viruses associated with host gene expression changes - Nature Biotechnology
A workflow using conserved amino acid domains identifies viruses in sequence data at single-cell resolution.
go.nature.com
April 22, 2025 at 2:15 PM
Very excited to finally see this out! 🦠🧬
Huge thanks to all of my amazing co-authors! @lpachter.bsky.social @delaneyksull.bsky.social
Original paper thread: x.com/neuroluebber...
Free access link to the paper: rdcu.be/eiIWC
Huge thanks to all of my amazing co-authors! @lpachter.bsky.social @delaneyksull.bsky.social
Original paper thread: x.com/neuroluebber...
Free access link to the paper: rdcu.be/eiIWC
Reposted by Delaney Sullivan
New preprint out!
This is probably my most important paper. To my deep chagrin, it has no math.
XIST is a non-coding RNA exclusive to XX females. It silences one of the X chromosomes.
So what is it doing in male heart Schwann cells?
This is probably my most important paper. To my deep chagrin, it has no math.
XIST is a non-coding RNA exclusive to XX females. It silences one of the X chromosomes.
So what is it doing in male heart Schwann cells?
Male XIST expression in cardiac pseudo-glia does not induce X chromosome inactivation https://www.biorxiv.org/content/10.1101/2025.04.09.648005v1
April 15, 2025 at 7:40 PM
New preprint out!
This is probably my most important paper. To my deep chagrin, it has no math.
XIST is a non-coding RNA exclusive to XX females. It silences one of the X chromosomes.
So what is it doing in male heart Schwann cells?
This is probably my most important paper. To my deep chagrin, it has no math.
XIST is a non-coding RNA exclusive to XX females. It silences one of the X chromosomes.
So what is it doing in male heart Schwann cells?
Reposted by Delaney Sullivan
New lawsuit filed today in Massachusetts aginst NIH from many state Attorneys General
First, plaintiffs seek relief for the unreasonable and intentional delays currently plaguing the grant-application process
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First, plaintiffs seek relief for the unreasonable and intentional delays currently plaguing the grant-application process
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April 4, 2025 at 4:33 PM
New lawsuit filed today in Massachusetts aginst NIH from many state Attorneys General
First, plaintiffs seek relief for the unreasonable and intentional delays currently plaguing the grant-application process
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First, plaintiffs seek relief for the unreasonable and intentional delays currently plaguing the grant-application process
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Reposted by Delaney Sullivan
🚨 BREAKING: I'm suing #RFKJr @ #HHS & #JayBhattacharya @ #NIH
Canceling medical research grants threatens innovations benefiting ALL Americans, no matter your politics! 🇺🇸
Thanks to my lawyers @aclu.org @aclum.bsky.social @protectdemocracy.org & @cspi.bsky.social
Long 🧵 on why I'm suing 👇
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Canceling medical research grants threatens innovations benefiting ALL Americans, no matter your politics! 🇺🇸
Thanks to my lawyers @aclu.org @aclum.bsky.social @protectdemocracy.org & @cspi.bsky.social
Long 🧵 on why I'm suing 👇
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April 2, 2025 at 7:52 PM
🚨 BREAKING: I'm suing #RFKJr @ #HHS & #JayBhattacharya @ #NIH
Canceling medical research grants threatens innovations benefiting ALL Americans, no matter your politics! 🇺🇸
Thanks to my lawyers @aclu.org @aclum.bsky.social @protectdemocracy.org & @cspi.bsky.social
Long 🧵 on why I'm suing 👇
1/
Canceling medical research grants threatens innovations benefiting ALL Americans, no matter your politics! 🇺🇸
Thanks to my lawyers @aclu.org @aclum.bsky.social @protectdemocracy.org & @cspi.bsky.social
Long 🧵 on why I'm suing 👇
1/
Reposted by Delaney Sullivan
Reposted by Delaney Sullivan
Revoking Congressionally appropriated funds based on political ideology is not just undemocratic, it's illegal. It's a gross misuse of American tax dollars, and it recklessly endangers everyone.
Grateful to my colleagues for standing against this. Enough is enough.
Grateful to my colleagues for standing against this. Enough is enough.
April 2, 2025 at 7:10 PM
Revoking Congressionally appropriated funds based on political ideology is not just undemocratic, it's illegal. It's a gross misuse of American tax dollars, and it recklessly endangers everyone.
Grateful to my colleagues for standing against this. Enough is enough.
Grateful to my colleagues for standing against this. Enough is enough.
Reposted by Delaney Sullivan
F mechanisms (New and Competitive renewals)
Oof!
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Oof!
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March 29, 2025 at 12:58 PM
F mechanisms (New and Competitive renewals)
Oof!
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Oof!
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Reposted by Delaney Sullivan
I am livid that my student who submitted a diversity F31 and received an outstanding score, near the top of the fundable range, was told to submit again.
Refusing to fund F31s from URMs while funding regular F31s from white/privileged students with worse scores is blatant discrimination.
Refusing to fund F31s from URMs while funding regular F31s from white/privileged students with worse scores is blatant discrimination.
March 18, 2025 at 7:13 PM
I am livid that my student who submitted a diversity F31 and received an outstanding score, near the top of the fundable range, was told to submit again.
Refusing to fund F31s from URMs while funding regular F31s from white/privileged students with worse scores is blatant discrimination.
Refusing to fund F31s from URMs while funding regular F31s from white/privileged students with worse scores is blatant discrimination.
Reposted by Delaney Sullivan
Just wanted to give a shoutout to @marimo.io (cc @akshaykagrawal.bsky.social ). If u have been using Jupyter Notebooks, u should REALLY try Marimo. It is such an upgrade. We have been actively developing on it in the lab (integration with NLP LLMs) as well & are huge fans. Strongly recommend.
March 5, 2025 at 10:29 PM
Just wanted to give a shoutout to @marimo.io (cc @akshaykagrawal.bsky.social ). If u have been using Jupyter Notebooks, u should REALLY try Marimo. It is such an upgrade. We have been actively developing on it in the lab (integration with NLP LLMs) as well & are huge fans. Strongly recommend.
Reposted by Delaney Sullivan
More great reporting from Judd Legum at Popular...Great in terms of getting the receipts, definitely not great in terms of what is happening...
popular.info/p/update-nih...
popular.info/p/update-nih...
UPDATE: NIH reimposes "DEI" funding freeze despite court order
The National Institutes of Health (NIH) is still blocking most ongoing scientific funding over concerns about "diversity, equity and inclusion" (DEI), according to NIH sources and internal NIH corresp...
popular.info
February 24, 2025 at 8:34 PM
More great reporting from Judd Legum at Popular...Great in terms of getting the receipts, definitely not great in terms of what is happening...
popular.info/p/update-nih...
popular.info/p/update-nih...
Reposted by Delaney Sullivan
for any others who applied to diversity-related NIH grants that are being affected by the DEIA ban, if you'd like to join a whatsapp group (for support + looking into legal options) reply to this post & i'll DM you a join link!
February 7, 2025 at 12:47 PM
for any others who applied to diversity-related NIH grants that are being affected by the DEIA ban, if you'd like to join a whatsapp group (for support + looking into legal options) reply to this post & i'll DM you a join link!
Reposted by Delaney Sullivan
And now back to our regularly scheduled $hitshow
The dismantling of NIH programs to increase diversity in the biomedical workforce and the abhorrent treatment of talented young scientists
The dismantling of NIH programs to increase diversity in the biomedical workforce and the abhorrent treatment of talented young scientists
a cartoon of homer simpson holding a card
ALT: a cartoon of homer simpson holding a card
media.tenor.com
February 9, 2025 at 12:51 PM
And now back to our regularly scheduled $hitshow
The dismantling of NIH programs to increase diversity in the biomedical workforce and the abhorrent treatment of talented young scientists
The dismantling of NIH programs to increase diversity in the biomedical workforce and the abhorrent treatment of talented young scientists
Reposted by Delaney Sullivan
ATTENTION
If you are someone who had an F31-Diversity (or similar) application submitted this cycle, please DM me here, contact me on signal (jeremymberg.78), or email me at jeremymberg@gmail.com.
I will keep all information confidential.
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If you are someone who had an F31-Diversity (or similar) application submitted this cycle, please DM me here, contact me on signal (jeremymberg.78), or email me at jeremymberg@gmail.com.
I will keep all information confidential.
2/n
February 7, 2025 at 4:06 PM
ATTENTION
If you are someone who had an F31-Diversity (or similar) application submitted this cycle, please DM me here, contact me on signal (jeremymberg.78), or email me at jeremymberg@gmail.com.
I will keep all information confidential.
2/n
If you are someone who had an F31-Diversity (or similar) application submitted this cycle, please DM me here, contact me on signal (jeremymberg.78), or email me at jeremymberg@gmail.com.
I will keep all information confidential.
2/n