Dave Grainger
@degrainger.bsky.social
Developmental biologist studying endothelial cell differentiation and heterogeneity
Postdoc in the Stone Lab - Institute of Developmental and Regenerative Medicine, Oxford, UK
Postdoc in the Stone Lab - Institute of Developmental and Regenerative Medicine, Oxford, UK
Pinned
Dave Grainger
@degrainger.bsky.social
· Jan 13
Direct specification of lymphatic endothelium from mesenchymal progenitors - Nature Cardiovascular Research
Lupu, Grainger, Kirschnick et al. show that, contrary to prevailing belief, the initial specification of mammalian lymphatic endothelial cells primarily occurs from previously unidentified mesenchymal...
doi.org
A huge thank you to all my co-authors, particularly Irina Lupu, Nils Kirschnick, @oliverastone.bsky.social and Friedemann Kiefer
I am grateful to have been part of a project that opens so many exciting questions for the field
For more details, please read our paper:
doi.org/10.1038/s441...
I am grateful to have been part of a project that opens so many exciting questions for the field
For more details, please read our paper:
doi.org/10.1038/s441...
Reposted by Dave Grainger
Yesterday it was cows using tools, today its penguins using satellite imagery.
January 20, 2026 at 6:44 PM
Yesterday it was cows using tools, today its penguins using satellite imagery.
Reposted by Dave Grainger
Please check out our job post @biologists.bsky.social!
We are recruiting a Postdoc Scientist to develop cutting-edge tools and techniques for bioengineering human lymphatic networks, as part of an interdisciplinary collaboration with the group of Prof Dame Molly Stevens!
bit.ly/3La9idq
We are recruiting a Postdoc Scientist to develop cutting-edge tools and techniques for bioengineering human lymphatic networks, as part of an interdisciplinary collaboration with the group of Prof Dame Molly Stevens!
bit.ly/3La9idq
Postdoctoral position in vascular bioengineering in Oxford, UK - the Node
The Stone Group at the Institute of Developmental and Regenerative Medicine, University of Oxford, is looking for a motivated Postdoctoral Research Scientist to develop tools and techniques that enabl...
bit.ly
December 20, 2025 at 9:39 AM
Please check out our job post @biologists.bsky.social!
We are recruiting a Postdoc Scientist to develop cutting-edge tools and techniques for bioengineering human lymphatic networks, as part of an interdisciplinary collaboration with the group of Prof Dame Molly Stevens!
bit.ly/3La9idq
We are recruiting a Postdoc Scientist to develop cutting-edge tools and techniques for bioengineering human lymphatic networks, as part of an interdisciplinary collaboration with the group of Prof Dame Molly Stevens!
bit.ly/3La9idq
Reposted by Dave Grainger
Today’s #ScientificImage — “Where Vessels Begin,” comes from @degrainger.bsky.social, a postdoctoral researcher in IDRM's Stone group.
💬"We are working to understand how blood and lymphatic vessels form during embryonic development and how organ-specific characteristics of these vessels arise."
💬"We are working to understand how blood and lymphatic vessels form during embryonic development and how organ-specific characteristics of these vessels arise."
November 6, 2025 at 10:06 AM
Today’s #ScientificImage — “Where Vessels Begin,” comes from @degrainger.bsky.social, a postdoctoral researcher in IDRM's Stone group.
💬"We are working to understand how blood and lymphatic vessels form during embryonic development and how organ-specific characteristics of these vessels arise."
💬"We are working to understand how blood and lymphatic vessels form during embryonic development and how organ-specific characteristics of these vessels arise."
Our Institute for Desperately Regrowing Moustaches @idrm.ox.ac.uk is raising money for men’s mental health, suicide prevention, and prostate and testicular cancer awareness by growing moustaches. Please donate on our Movember page if you're able!
movember.com/t/institute-...
movember.com/t/institute-...
Institute of Developmental and Regenerative Medicine (IDRM)'s Mo Space
Movember, the month formerly known as November, is a moustache growing charity event held during November each year that raises funds and awareness for men's health.
movember.com
November 2, 2025 at 2:50 PM
Our Institute for Desperately Regrowing Moustaches @idrm.ox.ac.uk is raising money for men’s mental health, suicide prevention, and prostate and testicular cancer awareness by growing moustaches. Please donate on our Movember page if you're able!
movember.com/t/institute-...
movember.com/t/institute-...
Reposted by Dave Grainger
Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcoding
The formation of neural circuits depends on the precise spatial and temporal organisation of neuronal populations during development. In the vertebrate spinal cord, progenitors are patterned into mole...
www.biorxiv.org
October 26, 2025 at 5:15 PM
Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
BBC News - Pictured: Winning entries for Wildlife Photographer of the Year 2025 - BBC News
www.bbc.co.uk/news/article...
www.bbc.co.uk/news/article...
Pictured: Winning entries for Wildlife Photographer of the Year 2025
South African photographer Wim van den Heever takes the main prize for his shot
www.bbc.co.uk
October 15, 2025 at 6:01 PM
BBC News - Pictured: Winning entries for Wildlife Photographer of the Year 2025 - BBC News
www.bbc.co.uk/news/article...
www.bbc.co.uk/news/article...
Reposted by Dave Grainger
Do zebrafish regenerate their hearts equally? In our new paper at the @tillymommersteeg.bsky.social lab we uncovered variations in the regenerative response of 7 wt zebrafish strains leading us to identify a critical role of oxidative phosphorylation in long-term heart regeneration.
rdcu.be/eI1v5
rdcu.be/eI1v5
Oxidative phosphorylation is required for cardiomyocyte re-differentiation and long-term fish heart regeneration
Nature Cardiovascular Research - Lekkos et al. show that a metabolic switch toward oxidative phosphorylation is required for cardiomyocyte re-differentiation and heart regeneration after injury in...
rdcu.be
October 1, 2025 at 11:26 AM
Do zebrafish regenerate their hearts equally? In our new paper at the @tillymommersteeg.bsky.social lab we uncovered variations in the regenerative response of 7 wt zebrafish strains leading us to identify a critical role of oxidative phosphorylation in long-term heart regeneration.
rdcu.be/eI1v5
rdcu.be/eI1v5
Reposted by Dave Grainger
See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
October 1, 2025 at 6:21 PM
See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
Whether you're into photography or not there's something here for everyone. Some amazing shots
www.britishphotographyawards.org/2025-shortli...
www.britishphotographyawards.org/2025-shortli...
British Photography Awards
The British Photography Awards is a charity oriented photography prize open to all UK residents and British photographers the world over
www.britishphotographyawards.org
September 24, 2025 at 11:09 PM
Whether you're into photography or not there's something here for everyone. Some amazing shots
www.britishphotographyawards.org/2025-shortli...
www.britishphotographyawards.org/2025-shortli...
Whew the most amazing I've ever seen the sea. Off the coast of Kerry, Ireland
September 10, 2025 at 9:41 PM
Whew the most amazing I've ever seen the sea. Off the coast of Kerry, Ireland
Reposted by Dave Grainger
ICYMI – Our featured image was this beautiful colour-coded depth projection of the blood endothelial cells of the mouse embryonic thymus & surrounding structures.
The image was acquired by David Grainger. Find out about David’s research⤵️
focalplane.biologists.com/2025/08/29/f...
#SciArt
The image was acquired by David Grainger. Find out about David’s research⤵️
focalplane.biologists.com/2025/08/29/f...
#SciArt
Featured image with David Grainger - FocalPlane
Featured image with David Grainger - News
focalplane.biologists.com
September 4, 2025 at 12:12 PM
ICYMI – Our featured image was this beautiful colour-coded depth projection of the blood endothelial cells of the mouse embryonic thymus & surrounding structures.
The image was acquired by David Grainger. Find out about David’s research⤵️
focalplane.biologists.com/2025/08/29/f...
#SciArt
The image was acquired by David Grainger. Find out about David’s research⤵️
focalplane.biologists.com/2025/08/29/f...
#SciArt
Have a look at my featured image with FocalPlane. It's a thymus, I swear 🦋
ICYMI – Our featured image was this beautiful colour-coded depth projection of the blood endothelial cells of the mouse embryonic thymus & surrounding structures.
The image was acquired by David Grainger. Find out about David’s research⤵️
focalplane.biologists.com/2025/08/29/f...
#SciArt
The image was acquired by David Grainger. Find out about David’s research⤵️
focalplane.biologists.com/2025/08/29/f...
#SciArt
Featured image with David Grainger - FocalPlane
Featured image with David Grainger - News
focalplane.biologists.com
September 5, 2025 at 9:04 AM
Have a look at my featured image with FocalPlane. It's a thymus, I swear 🦋
Reposted by Dave Grainger
“I’m not sure I want to give way to the right”
From the new Private Eye, in shops now.
From the new Private Eye, in shops now.
September 3, 2025 at 10:54 AM
“I’m not sure I want to give way to the right”
From the new Private Eye, in shops now.
From the new Private Eye, in shops now.
Reposted by Dave Grainger
Wow
'Here, we present a high-speed blockface volumetric imaging system with an optimized workflow of whole-body clearing, capable of imaging the entire adult mouse at micrometer resolution within 40 h.'
www.cell.com/cell/fulltex...
'Here, we present a high-speed blockface volumetric imaging system with an optimized workflow of whole-body clearing, capable of imaging the entire adult mouse at micrometer resolution within 40 h.'
www.cell.com/cell/fulltex...
High-speed mapping of whole-mouse peripheral nerves at subcellular resolution
A high-speed pipeline enables whole-mouse imaging and mesoscopic analysis of peripheral
nerves using transgenic, immunostaining, and viral labeling, providing an effective
means to map body-wide struc...
www.cell.com
August 25, 2025 at 5:40 AM
Wow
'Here, we present a high-speed blockface volumetric imaging system with an optimized workflow of whole-body clearing, capable of imaging the entire adult mouse at micrometer resolution within 40 h.'
www.cell.com/cell/fulltex...
'Here, we present a high-speed blockface volumetric imaging system with an optimized workflow of whole-body clearing, capable of imaging the entire adult mouse at micrometer resolution within 40 h.'
www.cell.com/cell/fulltex...
Giant fiancée took me out for my nearly-birthday
August 16, 2025 at 9:06 PM
Giant fiancée took me out for my nearly-birthday
Reposted by Dave Grainger
Thrilled that our paper is in print @science.org!!
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
August 15, 2025 at 5:37 AM
Thrilled that our paper is in print @science.org!!
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
Looking forward to the Spa GP this weekend. Ferrari sharing some cool artwork this week
July 23, 2025 at 3:32 PM
Looking forward to the Spa GP this weekend. Ferrari sharing some cool artwork this week
Reposted by Dave Grainger
Excited to share our new collaborative preprint between @uclnews.bsky.social and @sickkidsto.bsky.social 🥳
We found that kidney lymphatic vessels, an emerging target in kidney diseases, partly arises from the same group of cells that give rise to the kidney
www.biorxiv.org/content/10.1...
(1/4)
We found that kidney lymphatic vessels, an emerging target in kidney diseases, partly arises from the same group of cells that give rise to the kidney
www.biorxiv.org/content/10.1...
(1/4)
Genetic lineage tracing identifies intermediate mesoderm as a novel contributor to mammalian kidney lymphatics
The lymphatic vasculature is essential for fluid homeostasis, immune regulation and possesses diverse organ-specific functions. During development, lymphatic endothelial cells (LEC) arise from multipl...
www.biorxiv.org
July 22, 2025 at 8:17 PM
Excited to share our new collaborative preprint between @uclnews.bsky.social and @sickkidsto.bsky.social 🥳
We found that kidney lymphatic vessels, an emerging target in kidney diseases, partly arises from the same group of cells that give rise to the kidney
www.biorxiv.org/content/10.1...
(1/4)
We found that kidney lymphatic vessels, an emerging target in kidney diseases, partly arises from the same group of cells that give rise to the kidney
www.biorxiv.org/content/10.1...
(1/4)
I've seen a massive influx of bot-looking accounts following me on here. Almost all only posting about US politics. Hope it doesn't drown out why I joined this platform like it did on twitter
July 20, 2025 at 5:37 PM
I've seen a massive influx of bot-looking accounts following me on here. Almost all only posting about US politics. Hope it doesn't drown out why I joined this platform like it did on twitter
Reposted by Dave Grainger
Register now to attend our #DevPres webinar next week, featuring the winners of the @bsdb.bsky.social poster prize, @shifaant.bsky.social and @giuliapaci.bsky.social, and chaired by Abigail Tucker.
4 June at 15:00 BST
us02web.zoom.us/webinar/regi...
4 June at 15:00 BST
us02web.zoom.us/webinar/regi...
May 28, 2025 at 1:32 PM
Register now to attend our #DevPres webinar next week, featuring the winners of the @bsdb.bsky.social poster prize, @shifaant.bsky.social and @giuliapaci.bsky.social, and chaired by Abigail Tucker.
4 June at 15:00 BST
us02web.zoom.us/webinar/regi...
4 June at 15:00 BST
us02web.zoom.us/webinar/regi...
Reposted by Dave Grainger
🎓 The MRC/BHF Centre of Research Excellence in Advanced Cardiac Therapies (REACT) is inviting applications for a fully funded DPhil studentship, based at the IDRM.
Learn more and apply: lnkd.in/gb-mEX8K
@oxforddpag.bsky.social
Learn more and apply: lnkd.in/gb-mEX8K
@oxforddpag.bsky.social
May 28, 2025 at 2:00 PM
🎓 The MRC/BHF Centre of Research Excellence in Advanced Cardiac Therapies (REACT) is inviting applications for a fully funded DPhil studentship, based at the IDRM.
Learn more and apply: lnkd.in/gb-mEX8K
@oxforddpag.bsky.social
Learn more and apply: lnkd.in/gb-mEX8K
@oxforddpag.bsky.social
My entry SMILE made it into the top ten 😁
Alongside many great entries. My favourite is Minnie's Bow!
Alongside many great entries. My favourite is Minnie's Bow!
See the winners of the YEN Image Competition 2025. Thanks for everyone who sent us their amazing embryology images!
#yen2025
thenode.biologists.com/yen-image-co...
#yen2025
thenode.biologists.com/yen-image-co...
YEN Image Competition 2025 - the Node
The winners of the Young Embryologist Network (YEN) 2025 Image Competition announcement.
thenode.biologists.com
May 20, 2025 at 9:56 PM
My entry SMILE made it into the top ten 😁
Alongside many great entries. My favourite is Minnie's Bow!
Alongside many great entries. My favourite is Minnie's Bow!
Great evening of talks at #pint25 in Oxford Tech Me Out theme. Very interesting talks from Alex and Jorge from @alpinef1.bsky.social followed by Muhammed Waqas from JLB.
Alpine even brought a front wing from their 2024 F1 car!
@pintofscience.uk
Alpine even brought a front wing from their 2024 F1 car!
@pintofscience.uk
May 19, 2025 at 8:30 PM
Great evening of talks at #pint25 in Oxford Tech Me Out theme. Very interesting talks from Alex and Jorge from @alpinef1.bsky.social followed by Muhammed Waqas from JLB.
Alpine even brought a front wing from their 2024 F1 car!
@pintofscience.uk
Alpine even brought a front wing from their 2024 F1 car!
@pintofscience.uk
Great weekend celebrating @emmarose64.bsky.social's graduation with friends and family. Very proud! 😊
May 18, 2025 at 6:35 PM
Great weekend celebrating @emmarose64.bsky.social's graduation with friends and family. Very proud! 😊
Reposted by Dave Grainger
We indeed got many entries!
May 2, 2025 at 6:09 PM
We indeed got many entries!