Christian Peace
@cgpeace.bsky.social
Postdoc in Rabinowitz lab at Princeton
Reposted by Christian Peace
Very excited to announce that the first paper from the lab is now live @natcomms.nature.com #mitochondria #immunometabolism
This work was led by postdoc Eloise marques with many important contributions from all of our co-authors.
Please check it out!
www.nature.com/articles/s41...
This work was led by postdoc Eloise marques with many important contributions from all of our co-authors.
Please check it out!
www.nature.com/articles/s41...
An inherited mitochondrial DNA mutation remodels inflammatory cytokine responses in macrophages and in vivo in mice - Nature Communications
Inherited mitochondrial DNA mutations can result in diverse clinical phenotypes. Here, the authors characterise a heteroplasmic tRNAAla mutation (m.5019A>G) in mice and demonstrate that macrophages...
www.nature.com
November 20, 2025 at 4:09 PM
Very excited to announce that the first paper from the lab is now live @natcomms.nature.com #mitochondria #immunometabolism
This work was led by postdoc Eloise marques with many important contributions from all of our co-authors.
Please check it out!
www.nature.com/articles/s41...
This work was led by postdoc Eloise marques with many important contributions from all of our co-authors.
Please check it out!
www.nature.com/articles/s41...
Reposted by Christian Peace
This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥
www.nature.com/articles/s42...
www.nature.com/articles/s42...
The source of dietary fat influences anti-tumour immunity in obese mice - Nature Metabolism
This study shows that animal-based high-fat diets accelerate tumour growth and impair anti-tumour response to melanoma in obese mice, whereas plant-based high-fat diets do not.
www.nature.com
July 28, 2025 at 3:02 PM
This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted by Christian Peace
Are you interested in #immunometabolism but not sure where to start?
Introducing our new book “Metabolites as Signals in Immunity and Inflammation”, co-edited with Zbigniew Zasłona and @lukeanthonyoneill.bsky.social (@tcddublin.bsky.social), available now.
shop.elsevier.com/books/metabo...
(1/n)
Introducing our new book “Metabolites as Signals in Immunity and Inflammation”, co-edited with Zbigniew Zasłona and @lukeanthonyoneill.bsky.social (@tcddublin.bsky.social), available now.
shop.elsevier.com/books/metabo...
(1/n)
July 10, 2025 at 3:26 PM
Are you interested in #immunometabolism but not sure where to start?
Introducing our new book “Metabolites as Signals in Immunity and Inflammation”, co-edited with Zbigniew Zasłona and @lukeanthonyoneill.bsky.social (@tcddublin.bsky.social), available now.
shop.elsevier.com/books/metabo...
(1/n)
Introducing our new book “Metabolites as Signals in Immunity and Inflammation”, co-edited with Zbigniew Zasłona and @lukeanthonyoneill.bsky.social (@tcddublin.bsky.social), available now.
shop.elsevier.com/books/metabo...
(1/n)
Elegant work on complex I and ROS in macrophages
Great to see paper from Alva Casey out today in Nature Metabolism - from her PhD.
Well done Alva!
doi.org/10.1038/s422...
Well done Alva!
doi.org/10.1038/s422...
Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation - Nature Metabolism
Casey et al. explore the basic mechanisms of mitochondrial superoxide production and its impact on interleukin-1β production in LPS-treated macrophages.
doi.org
February 19, 2025 at 8:28 PM
Elegant work on complex I and ROS in macrophages
Reposted by Christian Peace
Hello aging/metabolism people. I have a preprint now available about metabolic fluxes in aged mice. Please read and feel free to share ^_^
papers.ssrn.com/sol3/papers....
papers.ssrn.com/sol3/papers....
Aged Mice Exhibit Widespread Metabolic Changes But Preserved Major Fluxes
Metabolic dysregulation is a hallmark of aging. Here we investigate age-induced metabolic alterations in mice using metabolomics and stable-isotope tracing. Cir
papers.ssrn.com
December 27, 2024 at 3:30 PM
Hello aging/metabolism people. I have a preprint now available about metabolic fluxes in aged mice. Please read and feel free to share ^_^
papers.ssrn.com/sol3/papers....
papers.ssrn.com/sol3/papers....
Reposted by Christian Peace
New studies from our lab by Tevis Vitale and Jason Liang in @naturecancer.bsky.social Selective deficiency of complex I subunits causes tumor immunogenicity via T cell surveillance and Immune Checkpoint Blockade responsiveness Collaboration with Widlund, Gygi and Wucherpfennig labs rdcu.be/d6BgJ
January 17, 2025 at 11:16 AM
New studies from our lab by Tevis Vitale and Jason Liang in @naturecancer.bsky.social Selective deficiency of complex I subunits causes tumor immunogenicity via T cell surveillance and Immune Checkpoint Blockade responsiveness Collaboration with Widlund, Gygi and Wucherpfennig labs rdcu.be/d6BgJ
Reposted by Christian Peace
Pro-inflammatory macrophage activation does not require inhibition of oxidative phosphorylation | EMBO reports
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
Pro-inflammatory macrophage activation does not require inhibition of oxidative phosphorylation | EMBO reports
imageimageA reduction in oxidation phosphorylation is considered to be a hallmark of pro-inflammatory
macrophage polarization. This study shows that respiratory inhibition is not required
for macropha...
www.embopress.org
January 6, 2025 at 3:58 PM
Pro-inflammatory macrophage activation does not require inhibition of oxidative phosphorylation | EMBO reports
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....