Carmen De Miguel, PhD, MS, FAHA
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carmendemigue12.bsky.social
Carmen De Miguel, PhD, MS, FAHA
@carmendemigue12.bsky.social
Kidney physiologist, biomedical researcher; investigating the role of inflammation in hypertensive and diabetic kidney disease; Assistant Professor
Twitter: @carmendemigue12
Reposted by Carmen De Miguel, PhD, MS, FAHA
Single-chain TS2/16 integrin β1-activating antibody as a soluble supplement

up to 10-fold ⏫ yields of 2D/3D Visceral (small intestine, colon, stomach, pancreas/liver) Organoids🤠

Impact on blood vessel organoids/assembloids?😆

@hansclevers.bsky.social #NatBiotech 2025
www.nature.com/articles/s41...
October 31, 2025 at 12:10 PM
Reposted by Carmen De Miguel, PhD, MS, FAHA
🚨 New study alert: The American Heart Association’s latest “Cardiovascular-Kidney-Metabolic Syndrome” (CKM) metrics reveal major implications for life expectancy in U.S. adults. Dive into the full life-table analysis 👉 https://ow.ly/MtOT50XkE9P
#CardioSky #MedSky
October 30, 2025 at 9:35 PM
Reposted by Carmen De Miguel, PhD, MS, FAHA
Mesenchymal thymic niche cells enable regeneration of the adult thymus and T cell immunity @natbiotech.nature.com
www.nature.com/articles/s41... www.nature.com/articles/s41...
Mesenchymal thymic niche cells enable regeneration of the adult thymus and T cell immunity - Nature Biotechnology
T cell immunity declines with thymic atrophy, but thymic cell grafts rescue T cell function.
www.nature.com
October 31, 2025 at 1:15 AM
Reposted by Carmen De Miguel, PhD, MS, FAHA
'Here, we present a multi-organ single-cell atlas encompassing 23 fetal and adult organs, integrating scRNA-seq & scTCR-seq fm over 2.8 million immune cells across 15 second-trimester fetal & 4 adult donors.'
#Immunology
Systemic immune activity occurs during human immune system maturation
Profiling of immune cells from consecutive developmental time points in second-trimester fetuses and adults reveals that immune activation, immune tolerance, and hematopoiesis occur in a systemic way ...
www.cell.com
October 30, 2025 at 10:26 PM
Reposted by Carmen De Miguel, PhD, MS, FAHA
We are accepting applications for the JAMA Editorial Fellowship Program.

This remote fellowship is an opportunity for early career researchers to immerse themselves in the editorial process of a top-tier medical journal and receive hands-on mentorship from a JAMA Editor.

ja.ma/48XuUmI
October 31, 2025 at 10:00 AM
Reposted by Carmen De Miguel, PhD, MS, FAHA
@lucianomartelotto, not on Bluesky, on a new Spatial RNA imaging method, PRISM. www.nature.com/articles/s41... Now added to #SingleCell #Spatial #Method bit.ly/scmethodstable
High-plex spatial RNA imaging in one round with conventional microscopes using color-intensity barcodes - Nature Biotechnology
The 64-plex fluorescence imaging of RNA in tissues is achieved in one imaging cycle
www.nature.com
October 31, 2025 at 10:08 AM
Reposted by Carmen De Miguel, PhD, MS, FAHA
#Alzeimer disease is more common in women than men.

Often attributed to the fact that women tend to live longer, research shows the sex gap likely stems from a complex mix of biological and sociocultural factors.

ja.ma/47fkQEw
Why Is Alzheimer Disease More Common in Women?
This Medical News article discusses the biological and sociocultural factors that may contribute to sex-based differences in Alzheimer disease prevalence and progression.
ja.ma
October 31, 2025 at 11:00 AM
Reposted by Carmen De Miguel, PhD, MS, FAHA
Top Cited Review Article: How and Why Does Metabolism Scale with Body Mass?

Craig R. White and Dustin J. Marshall
doi.org/10.1152/phys...
#MetabolicRate #Scaling #Constraint
October 31, 2025 at 12:00 PM
Reposted by Carmen De Miguel, PhD, MS, FAHA
𝗜𝗦𝗡 𝗩𝗜𝗗𝗘𝗢 𝗔𝗕𝗦𝗧𝗥𝗔𝗖𝗧 𝗦𝗘𝗥𝗜𝗘𝗦: Targeted delivery of IL-21 nanotherapeutics to lymph nodes and kidney allografts attenuates B cell alloimmunity. 2025 from
@kidneyint.bsky.social www.kidney-internati...

#VideoAbstract by @dilushiwijay.bsky.social
October 31, 2025 at 12:00 PM
Reposted by Carmen De Miguel, PhD, MS, FAHA
📣 ATTN, #NephFellows! Apply for the NIT Fellows' Debate at SCM26 in New Orleans! Selected fellows will receive complimentary registration.

Applications due: 12/1 at 11:59pm ET
👉 Apply today: bit.ly/4qp10y7

#Nephrology #MedEd @NephMadness
October 31, 2025 at 12:02 PM
Reposted by Carmen De Miguel, PhD, MS, FAHA
The latest empadata dump: @nephroseeker.medsky.social writes up a #NephJC short on the meta analysis

www.nephjc.com/news/2025/10...
Empagliflozin, the kidney, and what we still don’t understand — NephJC
NephJC short on an empagliflozin meta-analysis
www.nephjc.com
October 21, 2025 at 12:03 AM
Reposted by Carmen De Miguel, PhD, MS, FAHA
Huge congratulations to @bruder-thiago.bsky.social for his amazing body of work. Well-deserved recipient of the Harry Goldblatt award
@ahascience.bsky.social !!!
September 5, 2025 at 8:40 PM
Reposted by Carmen De Miguel, PhD, MS, FAHA
Great to see our UAB medical student MS3 Nicole Tyler to present at @AHAScience ❤️ #Hypertension25 #prediabetes #arterial stiffness in patients <35 years. @anastasiasmihaili.bsky.social @carmendemigue12.bsky.social @fjrios59.bsky.social
@spjuraschek.bsky.social
September 5, 2025 at 5:08 PM
Reposted by Carmen De Miguel, PhD, MS, FAHA
#ESCCongress 2025 with #WCCardio is this week & we can’t wait to welcome the global community for a career-defining experience.

🌍 Join online and be part of Cardiology Beyond Borders, with access to the full Scientific Programme.
Register today: bit.ly/3HQqClX

29 August – 1 September
August 25, 2025 at 7:39 AM
Reposted by Carmen De Miguel, PhD, MS, FAHA
¿Has vivido o trabajado fuera de España?
🧪¿Conoces cómo se apoya el emprendimiento científico en otros países?
🗣️ ¡Queremos saberlo!
✨RAICEX lanza una encuesta abierta a todas las personas investigadoras.
🔗 docs.google.com/forms/d/e/1F...
📩 ciem@raicex.org
Encuesta informe emprendimiento RAICEX 2025
Desde la Comisión de Ciencia y Empresa de la Red de Asociaciones de Investigadores y Científicos Españoles en el Exterior (RAICEX) estamos elaborando un informe internacional sobre emprendimiento cien...
docs.google.com
August 7, 2025 at 8:23 AM
Reposted by Carmen De Miguel, PhD, MS, FAHA
New York Times story with profiles of researchers whose grants were terminated.

[Gift Link]

www.nytimes.com/2025/08/24/o...
Opinion | America First? Not When It Comes to Your Health.
www.nytimes.com
August 24, 2025 at 1:08 PM
Reposted by Carmen De Miguel, PhD, MS, FAHA
Research on effects of moderate-intensity #aerobic #exercise on #obesity induced changes in perivascular #adipose tissue in female mice shows partial restoration of the anti-contractile #vascular response and reduced #inflammation.
doi.org/10.14814/phy...
#Biomarkers #FemalePhysiology
August 25, 2025 at 9:15 AM
Reposted by Carmen De Miguel, PhD, MS, FAHA
Most viewed this week from JAMA: Restrictive platelet transfusion strategies are recommended to minimize adverse reactions, mitigate platelet shortages, reduce costs, and ensure patient-centric care.

ja.ma/45yYrkQ
August 25, 2025 at 11:00 AM
Reposted by Carmen De Miguel, PhD, MS, FAHA
CALL FOR PAPERS CLOSING SOON

Focusing on:
🔌 Brain circuitry
🫁 Cardiorespiratory control
⌛ Lifespan
🫀 Cardiorespiratory disease
🧠 (Mal)adaptive brain changes

⏰ Deadline: 31st August

For full information & how to submit🔗 buff.ly/11bN3Sm
August 25, 2025 at 11:01 AM
Reposted by Carmen De Miguel, PhD, MS, FAHA
The ISN Rare Kidney Diseases Toolkit offers concise, expert-led guidance to support timely recognition and informed decision-making in complex cases. Check out our latest tool on ADPKD and explore even more resources in the toolkit.

http://lite.spr.ly/6...
August 25, 2025 at 12:00 PM
Reposted by Carmen De Miguel, PhD, MS, FAHA
⏳@ahascience.bsky.social #Hypertension25 starting 13 d🙌

Very much looking fwd🔥#science & discussion of 2025 #BloodPressure #Hypertension #GLs & Debate🥊: Efficiency in #BloodPressure Measurement

@spjuraschek.bsky.social @daichishimbo.bsky.social @drwanpen.bsky.social @carmendemigue12.bsky.social
August 22, 2025 at 12:28 PM
Reposted by Carmen De Miguel, PhD, MS, FAHA
This conflation has irked me for years. People seem to think DEI and health disparities are synonymous. While DEI efforts may help with issues such as wealth inequality & educational attainment, which may help shrink health disparities in the long run, these are essentially two separate issues!
Post Sunday morning shows Bhattacharya email...
July 27, 2025 at 8:05 PM
Reposted by Carmen De Miguel, PhD, MS, FAHA
🧂Our controlled feeding pilot trial suggests potential sex differences in kidney responses to dietary salt. With a high salt diet, females may increase endothelin-1 excretion more. Endothelin-1 is a potent vasoconstrictor peptide and promotes salt excretion by the kidneys.
August 19, 2025 at 7:31 PM
Reposted by Carmen De Miguel, PhD, MS, FAHA
Calling all @apsphysiology.bsky.social members: let’s help raise some money to support ABRCMS student presentation awards! Goal is $1200/discipline to support 12 awards by Sept 30th! 🧪 abrcms.org/donate/stude...
ABRCMS Fundraising - Student Presentation Awards - ABRCMS
Judges – Help Us Raise Funds for Student Presentation Awards Thank you for your service as a judge at ABRCMS. Your dedication has helped shape the future of countless student scientists, and we’re dee...
abrcms.org
August 21, 2025 at 2:15 AM
Reposted by Carmen De Miguel, PhD, MS, FAHA
Join me in donating to ABRCMS. For many of us early in our careers (and for many of us now), this is THE conference. Let’s make sure future generations get the same experience.

I was told if each poster judge donated $25, their goal would be quickly met, but I think we can do better! 🙏🏾💪🏾
August 21, 2025 at 2:48 AM