Alex Carll, PhD, MSPH
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cardiocarll.bsky.social
Alex Carll, PhD, MSPH
@cardiocarll.bsky.social
19 followers 23 following 11 posts
Associate Professor of physiology passionately studying how environmental stressors harm the heart. Environmental cardiologist. 🔥 🫁 🧠🫀
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Reposted by Alex Carll, PhD, MSPH
bpdelisle.bsky.social
🚨🆕🧪🔬on 💓🕒 Delisle et al. 😉show the circadian clock gene BMAL1 drives sex-specific daily patterns in cardiac ion channels ⚡️❤️‍🔥 in 🐭, shaping when arrhythmias may strike in males vs females 🧠➡️❤️
#Circadian #Physiology #Heart #Arrhythmia #Sex #Science #Cardiosky
www.sciencedirect.com/science/arti...
BMAL1 mediates sex-specific circadian regulation of cardiac ion channels and temporal arrhythmia vulnerability
www.sciencedirect.com
November 9, 2025 at 1:01 PM
cardiocarll.bsky.social
Congrats to Brittany Reynolds of @cardiometabosci.bsky.social for successfully defending her dissertation today! Way to represent the team with a straightforward talk and meaningful insights how e-cig exposures evoke arrhythmias! Now to get this last cherry on the top submitted and published!
October 28, 2025 at 8:55 PM
cardiocarll.bsky.social
Today’s nanosecond pause in the news cycle 🥱 is a great excuse to hop on over to the AJP-Heart podcast about Brittany Reynolds’ concerning findings that vaping may increase postpartum arrhythmias 😱

E-cigs Promote Arrhythmias During Labor and Postpartum www.podbean.com/ew/pb-9t76s-...
E-cigs Promote Arrhythmias During Labor and Postpartum
In our latest episode, Associate Editor Dr. Jason Carter (Baylor University, Robbins College of Health and Human Sciences) interviews authors Dr. Alex Carll and Brittany Reynolds (University of Louisv...
www.podbean.com
October 27, 2025 at 4:10 PM
Reposted by Alex Carll, PhD, MSPH
cardioob.bsky.social
Pregnancy-Related CV Complications Are High & Rising

@emilyswlau.bsky.social @drklindley.bsky.social @abraguo.bsky.social
#CardioObstetrics #ACCRepOB #ACCCardioOB

@accintouch.bsky.social 🔗: www.acc.org/Latest-in-Ca...

@ahajournals.bsky.social 🔗: www.ahajournals.org/doi/10.1161/...
October 25, 2025 at 1:33 AM
Reposted by Alex Carll, PhD, MSPH
natureportfolio.nature.com
A single dose of psilocybin reduced pain, pain-induced anxiety and depression-like behaviors in mice, according to a study published in Nature Neuroscience. 🧪
Single-dose psilocybin rapidly and sustainably relieves allodynia and anxiodepressive-like behaviors in mouse models of chronic pain - Nature Neuroscience
Hammo et al. show that a single dose of psilocybin rapidly and sustainably relieves both chronic pain and anxiodepressive-like behaviors in mice by restoring prefrontal activity through partial agonism at 5-HT2A and 5-HT1A receptors.
go.nature.com
October 15, 2025 at 8:00 PM
cardiocarll.bsky.social
Recent interview about cardiopulmonary risks of vaping:

UofL scientist and physician discuss the health effects of e-cigarettes
Q&A with Alex Carll and Rodrigo Cavallazzi
@uoflenvirome.bsky.social @cardiometabosci.bsky.social @ciehs.bsky.social
www.uoflnews.com/section/scie...
UofL scientist and physician discuss the health effects of e-cigarettes | UofL News
Many people believe that electronic cigarettes are less harmful than traditional cigarettes, but research at the University of Louisville School of Medicine has shown that electronic cigarettes have a...
www.uoflnews.com
October 2, 2025 at 4:27 PM
Reposted by Alex Carll, PhD, MSPH
cardiometabosci.bsky.social
Don’t go vaping my heart, especially when pregnant💨 🫀🤰 Want to know why? Find out more in the latest publication by the Alex Carll, PhD, lab in AJP-Heart, led by PhD student, Brittany Reynolds. journals.physiology.org/doi/abs/10.1...
September 9, 2025 at 2:57 PM
cardiocarll.bsky.social
Proud of Anand Ramalingam for coalescing this data to show repeat e-cigarette exposure transiently evokes arrhythmias via the beta1 adrenoceptor, consistently increases BP, changes the cardiac proteome, and persistently depresses HR and ventricular repolarization. www.ahajournals.org/doi/full/10....
Acute and Persistent Cardiovascular Effects of Menthol E‐Cigarettes in Mice | Journal of the American Heart Association
www.ahajournals.org
April 30, 2025 at 6:00 PM
cardiocarll.bsky.social
Either the baristas at Heart Rhythm Society are superhuman, or they’re cheating. Either way, kudos #HRS2025
April 24, 2025 at 8:16 PM
Reposted by Alex Carll, PhD, MSPH
alice.soragnilab.com
The NCI grant supporting the Columbia comprehensive cancer center was terminated. Tell me how terminating support for cancer research helps the economy.

taggs.hhs.gov/Content/Data...
March 18, 2025 at 10:28 PM
Reposted by Alex Carll, PhD, MSPH
cardiometabosci.bsky.social
Tomorrow at #SOT25, Brittany Reynolds, a PhD student in the lab of Dr. Alex Carll, will present her current research on the effects of maternal e-cigarette exposure on cardiac electrophysiology and arrhythmia susceptibility. @sotoxicology.bsky.social @cardiocarll.bsky.social
March 18, 2025 at 9:34 PM
Reposted by Alex Carll, PhD, MSPH
cardiometabosci.bsky.social
Tomorrow at #SOT25, Romith Paily, a student in the lab of Dr. Alex Carll, will present his current findings on the effects of heat stress on cardiac electrophysiology and arrhythmia susceptibility. @cardiocarll.bsky.social @sotoxicology.bsky.social
March 16, 2025 at 2:28 PM
Reposted by Alex Carll, PhD, MSPH
drhelenecollin1.bsky.social
We need to make pregnancy and the postpartum period safe for all women. Currently, maternal mortality rates are at an all time high in the US. In order to make things safer, we need more funding, research, and representation. pubmed.ncbi.nlm.nih.gov/39832282/
Maternal cardiovascular research and education should be prioritized in the United States - PubMed
Maternal cardiovascular research and education should be prioritized in the United States
pubmed.ncbi.nlm.nih.gov
February 22, 2025 at 4:57 PM
Reposted by Alex Carll, PhD, MSPH
bpdelisle.bsky.social
🚨🫀🔬 Little et al reveal cardiac fibroblasts as major producers of high molecular weight hyaluronan post-heart attack heart ❤️‍🩹 Driven by HAS2- this ECM component accumulates but doesn’t impact fibroblast function 👉 journals.physiology.org/doi/abs/10.1...
#CardioSky #Physiology #Science
February 22, 2025 at 12:58 PM
Reposted by Alex Carll, PhD, MSPH
ciehs.bsky.social
Interested in moving environmental health research to policy? Join us for the John P. Wyatt Environment and Health Symposium, hosted by the University of Kentucky Center for the Environment.

Register now to attend online or in person: www.research.uky.edu/john-p-wyatt...
February 21, 2025 at 2:51 PM
Reposted by Alex Carll, PhD, MSPH
uoflenvirome.bsky.social
"The Healing Power of Trees": Read about the groundbreaking Green Heart Louisville Project in the latest issue of The Nature Conservancy Magazine. Green Heart is the first clinical trial to test a greening intervention the same way new drugs are tested. @nature.org

www.nature.org/en-us/magazi...
The Healing Power of Trees: A tree planting project improves the peoples' health
Adding 8,000 trees to a neighborhood in Louisville, Kentucky, improves health conditions that are linked to heart disease, stroke and some types of cancer.
www.nature.org
February 6, 2025 at 10:52 PM
Reposted by Alex Carll, PhD, MSPH
natureportfolio.nature.com
Temperature-related deaths in European cities could increase by up to 50% by the end of the century in the absence of climate change-mitigation policies, totalling up to 2.3 million additional deaths, suggests a paper published in Nature Medicine. https://go.nature.com/4glnYzU 🧪
This is figure 3, which shows city-level net changes in temperature-related excess death rates for each warming level under scenario SSP3-7.0 and no adaption to heat.
February 7, 2025 at 2:53 AM
cardiocarll.bsky.social
Taking Omega3s and VitD over three years slowed biological aging by 3-4 months when combined with exercise.

@ciehs.bsky.social @uoflenvirome.bsky.social
nature.com Nature @nature.com · Feb 3
Taking omega-3 and vitamin D supplements over a three-year period slowed biological ageing by three to four months, particularly when combined with exercise.

https://go.nature.com/4hjjGdO
Omega-3 supplements slow biological ageing
The anti-ageing effect was even greater when combined with vitamin D and exercise.
go.nature.com
February 3, 2025 at 6:52 PM
Reposted by Alex Carll, PhD, MSPH
natureportfolio.nature.com
A muscle patch developed using stem cells can help to repair failing hearts without adverse effects, according to a paper in Nature. #Medsky 🧪
Engineered heart muscle allografts for heart repair in primates and humans - Nature
Epicardial engineered heart muscle allografts from induced pluripotent stem cell-derived cardiomyocytes can safely and effectively remuscularize chronically failing hearts in rhesus macaques, leading to improved cardiac function and paving the way for human clinical trials.
go.nature.com
January 29, 2025 at 9:48 PM
Reposted by Alex Carll, PhD, MSPH
motherjones.com
The media has failed the public on a crucial matter: the derangement of Robert F. Kennedy Jr., writes @davidcorn.bsky.social.

News reports often describe him as a vaccine skeptic when he is far more dangerous than that.
The Madness of Robert F. Kennedy. Jr.
The depth of his extremism has not been fully conveyed to the public.
www.motherjones.com
January 29, 2025 at 1:19 PM
Reposted by Alex Carll, PhD, MSPH
bpdelisle.bsky.social
🚨🫀⏰ Delisle et al 😉 review circadian mechanisms and sudden cardiac death🧬 Day-night cycles in ion channel regulation and myocardial protection impact arrhythmia risk💓👉 www.jmcc-online.com/article/S002...
#IonChannels #Circadian #CardioSky #Arrhythmias #Physiology
Circadian influences on sudden cardiac death and cardiac electrophysiology
Cardiologists have analyzed daily patterns in the incidence of sudden cardiac death to identify environmental, behavioral, and physiological factors that trigger fatal arrhythmias. Recent studies have...
www.jmcc-online.com
January 28, 2025 at 1:04 AM
Reposted by Alex Carll, PhD, MSPH
nature.com
An extra 2.3 million people in European cities could die as a result of extreme temperatures — both hot and cold — by the end of the century

https://go.nature.com/42pFO1r
Extreme heat will kill millions of people in Europe without rapid action
Climate models predict that the number of heat-related deaths could soar in cities over the coming century, even when efforts are made to keep people safe.
go.nature.com
January 27, 2025 at 4:44 PM
cardiocarll.bsky.social
The thin silver lining of increasing job security for environmental health researchers may either tarnish or entirely evaporate over the next four years.

Trump administration halts proposed EPA limits on PFAS pollution www.ehn.org/trump-admini...
Trump administration halts proposed EPA limits on PFAS pollution
The Trump administration has withdrawn an EPA proposal to restrict PFAS discharges from industrial sites, prompting concern from environmental advocates about health risks and regulatory gaps.Shannon ...
www.ehn.org
January 27, 2025 at 2:13 PM