Brooks Benard
@brooksbenard.bsky.social
Staff scientist in the Gentles group at Stanford Pathology
Reposted by Brooks Benard
New #majetilab publication!
Asiri identifies 3 human MPP subsets from adult bone marrow and evaluates their engraftment + differentiation potential. Bonus: a single-cell multi-omics resource.
Check it out here ➡️ bit.ly/4mFSBEa
@stanforddeptmed.bsky.social @cp-cellreports.bsky.social
Asiri identifies 3 human MPP subsets from adult bone marrow and evaluates their engraftment + differentiation potential. Bonus: a single-cell multi-omics resource.
Check it out here ➡️ bit.ly/4mFSBEa
@stanforddeptmed.bsky.social @cp-cellreports.bsky.social
A single-cell framework identifies functionally and molecularly distinct multipotent progenitors in adult human hematopoiesis
Ediriwickrema et al. conducted a systematic evaluation of human bone marrow cells
and provide an updated model of adult hematopoiesis, which includes distinct, immunophenotypically
defined, multipoten...
bit.ly
September 4, 2025 at 4:59 PM
New #majetilab publication!
Asiri identifies 3 human MPP subsets from adult bone marrow and evaluates their engraftment + differentiation potential. Bonus: a single-cell multi-omics resource.
Check it out here ➡️ bit.ly/4mFSBEa
@stanforddeptmed.bsky.social @cp-cellreports.bsky.social
Asiri identifies 3 human MPP subsets from adult bone marrow and evaluates their engraftment + differentiation potential. Bonus: a single-cell multi-omics resource.
Check it out here ➡️ bit.ly/4mFSBEa
@stanforddeptmed.bsky.social @cp-cellreports.bsky.social
Excited to share that, a decade after its initial release, PRECOG has an update!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
PRECOG update: An augmented resource of clinical outcome associations with gene expression for pediatric and immunotherapy cohorts
Gene expression can be used to define prognostic and predictive biomarkers across cancers and treatment modalities. PRECOG (https://precog.stanford.edu) is a compendium of datasets with gene expressio...
www.biorxiv.org
August 28, 2025 at 7:21 PM
Excited to share that, a decade after its initial release, PRECOG has an update!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Brooks Benard
Looking forward to celebrating 80 years of federally funded science, technology and innovation @standupforscience.bsky.social SF, March 7, Civic Center, 1-3 pm 🧪 🧫 🧬
March 3, 2025 at 6:55 PM
Looking forward to celebrating 80 years of federally funded science, technology and innovation @standupforscience.bsky.social SF, March 7, Civic Center, 1-3 pm 🧪 🧫 🧬
Reposted by Brooks Benard
Happy to share a preprint from the Angelo lab many years in the making. Read on for a saga of multiplexed imaging, immunometabolism, and TB granulomas with some fun side quests into the realms of geographical information sciences and transcriptomics… (1/20) doi.org/10.1101/2025...
The immunometabolic topography of tuberculosis granulomas governs cellular organization and bacterial control
Despite being heavily infiltrated by immune cells, tuberculosis (TB) granulomas often subvert the host response to Mycobacterium tuberculosis (Mtb) infection and support bacterial persistence. We prev...
doi.org
February 24, 2025 at 10:16 PM
Happy to share a preprint from the Angelo lab many years in the making. Read on for a saga of multiplexed imaging, immunometabolism, and TB granulomas with some fun side quests into the realms of geographical information sciences and transcriptomics… (1/20) doi.org/10.1101/2025...
Reposted by Brooks Benard
AI provides a universal framework that leverages data and compute at scale to uncover higher-order patterns
Today, @arcinstitute.org in collaboration with Nvidia releases Evo 2—a fully open source biological foundation model trained on genomes spanning the entire tree of life.
Today, @arcinstitute.org in collaboration with Nvidia releases Evo 2—a fully open source biological foundation model trained on genomes spanning the entire tree of life.
February 19, 2025 at 4:35 PM
AI provides a universal framework that leverages data and compute at scale to uncover higher-order patterns
Today, @arcinstitute.org in collaboration with Nvidia releases Evo 2—a fully open source biological foundation model trained on genomes spanning the entire tree of life.
Today, @arcinstitute.org in collaboration with Nvidia releases Evo 2—a fully open source biological foundation model trained on genomes spanning the entire tree of life.
Reposted by Brooks Benard
Excited to post my first #skySplain about our recent work published yesterday in Nature Genetics! www.nature.com/articles/s41.... One of the first authors of this study - Annika Vannan – actually wrote this breakdown, but she's not yet over here on bluesky and asked me to post!
Spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis - Nature Genetics
Xenium spatial transcriptomic profiling of pulmonary fibrosis characterizes cell composition dynamics and histopathological features associated with the disease.
www.nature.com
February 4, 2025 at 2:11 PM
Excited to post my first #skySplain about our recent work published yesterday in Nature Genetics! www.nature.com/articles/s41.... One of the first authors of this study - Annika Vannan – actually wrote this breakdown, but she's not yet over here on bluesky and asked me to post!
Reposted by Brooks Benard
I’m super excited to share what I’ve been working on for the last (many) years: a spatial + genomic + transcriptomic characterization of how the breast cancer microenvironment evolves through immunotherapy! (1/x) 🧪🧬 🖥️ #AcademicSky #MLSky #ImmunoSky www.biorxiv.org/content/10.1...
Temporal and spatial composition of the tumor microenvironment predicts response to immune checkpoint inhibition
Immune checkpoint inhibition (ICI) has fundamentally changed cancer treatment. However, only a minority of patients with metastatic triple negative breast cancer (TNBC) benefit from ICI, and the deter...
www.biorxiv.org
January 29, 2025 at 4:17 PM
I’m super excited to share what I’ve been working on for the last (many) years: a spatial + genomic + transcriptomic characterization of how the breast cancer microenvironment evolves through immunotherapy! (1/x) 🧪🧬 🖥️ #AcademicSky #MLSky #ImmunoSky www.biorxiv.org/content/10.1...