Noah F. Greenwald
@noahgreenwald.bsky.social
Current postdoc at UCSF with @willowcoyote.bsky.social studying membrane proteins; PhD at Stanford developing spatial tools to study breast cancer with Mike Angelo & Christina Curtis
Pinned
Temporal and spatial composition of the tumor microenvironment predicts response to immune checkpoint inhibition
Immune checkpoint inhibition (ICI) has fundamentally changed cancer treatment. However, only a minority of patients with metastatic triple negative breast cancer (TNBC) benefit from ICI, and the deter...
www.biorxiv.org
I’m super excited to share what I’ve been working on for the last (many) years: a spatial + genomic + transcriptomic characterization of how the breast cancer microenvironment evolves through immunotherapy! (1/x) 🧪🧬 🖥️ #AcademicSky #MLSky #ImmunoSky www.biorxiv.org/content/10.1...
Reposted by Noah F. Greenwald
Happy to share a preprint from the Angelo lab many years in the making. Read on for a saga of multiplexed imaging, immunometabolism, and TB granulomas with some fun side quests into the realms of geographical information sciences and transcriptomics… (1/20) doi.org/10.1101/2025...
The immunometabolic topography of tuberculosis granulomas governs cellular organization and bacterial control
Despite being heavily infiltrated by immune cells, tuberculosis (TB) granulomas often subvert the host response to Mycobacterium tuberculosis (Mtb) infection and support bacterial persistence. We prev...
doi.org
February 24, 2025 at 10:16 PM
Happy to share a preprint from the Angelo lab many years in the making. Read on for a saga of multiplexed imaging, immunometabolism, and TB granulomas with some fun side quests into the realms of geographical information sciences and transcriptomics… (1/20) doi.org/10.1101/2025...
Reposted by Noah F. Greenwald
The Curtis Lab’s latest study on the genomic architecture of breast cancer from the pre-invasive to metastatic setting is now out in Nature! www.nature.com/articles/s41...
Complex rearrangements fuel ER+ and HER2+ breast tumours - Nature
A study identifies three dominant genomic archetypes of breast cancer induced by discrete mutational processes, describing a continuum of genomic profiles and detailing the mechanisms underlying the p...
www.nature.com
January 8, 2025 at 10:58 PM
The Curtis Lab’s latest study on the genomic architecture of breast cancer from the pre-invasive to metastatic setting is now out in Nature! www.nature.com/articles/s41...
I’m super excited to share what I’ve been working on for the last (many) years: a spatial + genomic + transcriptomic characterization of how the breast cancer microenvironment evolves through immunotherapy! (1/x) 🧪🧬 🖥️ #AcademicSky #MLSky #ImmunoSky www.biorxiv.org/content/10.1...
Temporal and spatial composition of the tumor microenvironment predicts response to immune checkpoint inhibition
Immune checkpoint inhibition (ICI) has fundamentally changed cancer treatment. However, only a minority of patients with metastatic triple negative breast cancer (TNBC) benefit from ICI, and the deter...
www.biorxiv.org
January 29, 2025 at 4:17 PM
I’m super excited to share what I’ve been working on for the last (many) years: a spatial + genomic + transcriptomic characterization of how the breast cancer microenvironment evolves through immunotherapy! (1/x) 🧪🧬 🖥️ #AcademicSky #MLSky #ImmunoSky www.biorxiv.org/content/10.1...
Reposted by Noah F. Greenwald
I wanted to write briefly about a very pleasant experience we recently had coordinating and collaborating closely on competing publications with 2 other teams. 1/
January 24, 2025 at 7:36 PM
I wanted to write briefly about a very pleasant experience we recently had coordinating and collaborating closely on competing publications with 2 other teams. 1/
Reposted by Noah F. Greenwald
Reposting our Penn Postdoctoral Fellowship in Genetics!
www.med.upenn.edu/apps/my/bpp_...
www.med.upenn.edu/apps/my/bpp_...
December 12, 2023 at 4:20 PM
Reposting our Penn Postdoctoral Fellowship in Genetics!
www.med.upenn.edu/apps/my/bpp_...
www.med.upenn.edu/apps/my/bpp_...
Hi all, I just joined! I’m a PhD student at Stanford studying tumor immunology. Excited to try this thing out #HiSciSky #AcademicSky
October 1, 2023 at 7:19 PM
Hi all, I just joined! I’m a PhD student at Stanford studying tumor immunology. Excited to try this thing out #HiSciSky #AcademicSky