Brooks Benard
brooksbenard.bsky.social
Brooks Benard
@brooksbenard.bsky.social
Staff scientist in the Gentles group at Stanford Pathology
All clinical and expression data, along with cell type proportion associations with outcomes, are publicly available at precog.stanford.edu.
Plots per-study MetaZ scores: Gene 1 (x) vs Gene 2 (y). Hover a point to see dataset + metadata.
precog.stanford.edu
August 28, 2025 at 7:21 PM
We integrated our existing pediatric data along with a newly curated ICI PRECOG resource into the PRECOG website, in addition to giving the site a UI overhaul.
August 28, 2025 at 7:21 PM
Additionally, the recent advent of immune checkpoint inhibitor (ICI) therapies in cancer nominates novel biomarkers of clinical response, and prompted us to update PRECOG for the immunotherapy age.
August 28, 2025 at 7:21 PM
Complimentary work from our group and others has provided similar expression-based biomarkers of outcomes in pediatric cancers (Pediatric PRECOG). However, this resource was never integrated into our online tool, limiting its accessibility and usefulness.

www.mdpi.com/2072-6694/13...
www.mdpi.com
August 28, 2025 at 7:21 PM
PRECOG has been a valuable resource for highlighting clinically relevant biomarkers across adult cancers. Additionally, it was one of the first comprehensive reports on the prognostic importance of the immune system in cancer.

www.nature.com/articles/nm....
The prognostic landscape of genes and infiltrating immune cells across human cancers - Nature Medicine
A searchable pan-cancer resource generated using data from nearly 18,000 human tumors reveals links between tumor infiltration by particular leukocyte subsets, tumor expression of particular gene sign...
www.nature.com
August 28, 2025 at 7:21 PM