Björn Rissiek
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brissiek.bsky.social
Björn Rissiek
@brissiek.bsky.social
Immunologist at the Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf in Hamburg, Germany. Does Nanobody Discovery, interested in neuroinflammation and purinergic signalling. My opinion are my own.
Hey #IUIS2025 participants, check out our poster on Wednesday, August 20, 12:15 - 13:45 | Poster Area (Hall X5) #neuroimmunology. We brought data from our new "BrEndO" mouse model for cerebral vasculitis #CD8 #Tcells #immunology
August 19, 2025 at 7:12 AM
Reposted by Björn Rissiek
Pretty certain running a lab is mostly about making signs to avoid inconveniences & minor catastrophes. 😊
August 10, 2025 at 2:34 AM
Today, our blood sample preparation container arrived. Still needs to be filled with equipment 😊 then we are ready for the first blood samples in October #nanobodies #vhh #antibodies #immunology
July 29, 2025 at 4:14 PM
Boost #1 of Campaign #1: done 🦙😊
July 24, 2025 at 4:18 PM
Rest in peace Ozzy 🥲 www.youtube.com/watch?v=zY5n... one of my favorite Black Sabbath songs
BLACK SABBATH - "War Pigs" from 'The End' (Live Video)
YouTube video by Black Sabbath
www.youtube.com
July 22, 2025 at 6:52 PM
Reposted by Björn Rissiek
#HotFromThePress !!

What if instead of analyzing 4-6 pathology markers you could check >100 in the *same* sample?

@maltekuehl.com & co @puellesv.bsky.social lab introduce #PathoPlex, method that could even predict disease

Full www.nature.com/articles/s41...
@focalplane.bsky.social @nature.com 🧪🔬
July 18, 2025 at 1:14 PM
Reposted by Björn Rissiek
It’s hard being a scientist these days and I’ve captured that indescribable feeling that we are all facing in a new word!!

open.substack.com/pub/profkap/...
Wissenschaftweltschmerz!
If you're a scientist, it's what you're feeling.
open.substack.com
July 14, 2025 at 2:48 AM
Today, we startet our first #nanobody discovery campaign by immunizing two of our alpacas, one by s.c. protein injection and one by gene gun. Crossing our fingers for a good HcAb response 🤞🏻💪🏻
July 10, 2025 at 9:10 PM
A warm welcome to our newest #nanobody discovery team member! “Occi” arrived this weekend and smothly joined the herd. Soon, she will help us generating new #nanobodies against antigen targets used in research and/or for medical application
July 6, 2025 at 7:18 PM
Should I check this #alpaca for #nanobodies conferring resistance to electric shock? … or should I first check the electric fence energiser 😆 #vhh #antibody
June 24, 2025 at 6:06 AM
Our alpaca mares have their summer coat since yesterday. Ethics are approved, antigen production is ongoing, and we hope to start the first round of immunization in July. Super excited!!! 🦙🧬🔬👨‍🔬
May 31, 2025 at 5:54 PM
Reposted by Björn Rissiek
Opinion | The Science I Would Be Doing if I Weren’t in ICE Detention
www.nytimes.com
May 13, 2025 at 12:56 PM
Reposted by Björn Rissiek
What does a science PhD really teach you? The ability to say “I don’t know, but I can find out.”
open.substack.com/pub/profkap/...
I have a particular set of skills
The first step to using them is saying “I don’t know”
open.substack.com
April 28, 2025 at 3:59 AM
Reposted by Björn Rissiek
Vaccines have saved 154 million lives in the past 50 years. A reminder of what is #HumanlyPossible. Science saves lives.
#VaccinesWork

bit.ly/wiw2025
April 27, 2025 at 1:46 PM
It is always a pleasure to get young students enthusiastic about science! A few days ago we had a whole class in our department, showcasing #Nanobody research. What can I say - it was fun! Hope to see some of you around on campus some time! #sfb1328
April 14, 2025 at 11:54 AM
I am happy to report that our chapter on "Flow Cytometric Analysis of Mouse Brain CD8+ T Cell Activation" is out now! It is part of a book on "T cell activation" curated and edited by Björn-Philipp Diercks of #sfb1328
link.springer.com/protocol/10....
Flow Cytometric Analysis of Mouse Brain CD8+ T Cell Activation
Cytotoxic CD8+ T cell lymphocytes are pivotal for fighting infections with intracellular pathogens, e.g., viruses. Moreover, recent studies have elucidated the role of CD8+ T cells in various neuroinf...
link.springer.com
April 14, 2025 at 11:43 AM
Reposted by Björn Rissiek
Not good.

75% of US scientists who answered Nature poll consider leaving www.nature.com/articles/d41...
March 27, 2025 at 5:22 PM
Reposted by Björn Rissiek
I received one of the 232 NIH grant "terminations" sent to scientists at Columbia last night. My research focuses on improving maternal and child health in the US. Also affected: ongoing clinical trials, research training programs, and research centers that aim to improve the health of Americans.
Hundreds of research grants at Columbia canceled following Trump edict, administrator says
The National Institutes of Health is terminating 232 grants for scientific research at Columbia University Irving Medical Center, according to an email an administrator sent to faculty.
gothamist.com
March 11, 2025 at 9:05 PM
Reposted by Björn Rissiek
Texas measles outbreak update: 124 cases, 18 hospitalized, & now the first death of a child, who was not vaccinated.

Tragic, preventable, & a direct consequence of the deadly lies spread by anti-vaxx grifters, one of whom is now the most powerful health official in the US.
February 26, 2025 at 5:34 PM
Exciting special issue coming up in 2025: #purinergic signaling is a fascinating cellular communication hub in many different organ and tissue systems…including the immune system. The special issue is curated and edited by colleagues from #SFB1328.

pubs.acs.org/doi/10.1021/...
Call for Papers – Purinergic Signaling: Medicinal Chemistry, Biology, Pharmacology, and Translation into Diagnostic and Therapeutic Drugs
OR SEARCH CITATIONS
pubs.acs.org
February 22, 2025 at 9:34 PM
Reposted by Björn Rissiek
Come and join our team at St. Jude Children's Research Hospital! We are seeking a Sr Scientist to advance our research on immune responses to infection/vaccination. This is a financially stable position offering a highly competitive salary and excellent benefits.
talent.stjude.org/careers/jobs...
Senior Scientist-Immunology, Vaccinology, Infection in Memphis, Tennessee | St. Jude Careers
St. Jude Careers is hiring a Senior Scientist-Immunology, Vaccinology, Infection in Memphis, Tennessee. Review all of the job details and apply today!
talent.stjude.org
January 17, 2025 at 2:10 PM
Reposted by Björn Rissiek
New approach: Nanobody inhibitors that target Ebolavirus are under development at Univ of Minnesota. Nanobodies are tiny antibodies from animals like alpacas allowing access to viral regions too small for larger antibodies. This one blocks EBV's ability to enter human cells phys.org/news/2025-01...
Scientists develop nanobody inhibitors to target deadly Ebola virus
Ebola virus, one of the deadliest pathogens, has a fatality rate of about 50%, posing a serious threat to global health and safety. To address this challenge, researchers at the University of Minnesot...
phys.org
January 8, 2025 at 11:12 AM
Reposted by Björn Rissiek
Our paper on nurturing a #PositiveResearchCulture within your #research #team published by @wellcometrust.bsky.social gives useful tips for your lab. As well as making you a good team leader, nurturing culture pays off in building your science: 1/11

wellcomeopenresearch.org/articles/9-3...
wellcomeopenresearch.org
January 14, 2025 at 9:55 AM
Reposted by Björn Rissiek
Excited to share our first paper of 2025, just published in @naturecomms.bsky.social 🧪🦠

Fantastic work by first author Zhao-Shan Chen and great collaboration with Qiyun Zhu and colleagues at Lanzhou Veterinary Research Institute.

Short thread below 🧵
rdcu.be/d5JEL

#ViroSky
Influenza A Virus H7 nanobody recognizes a conserved immunodominant epitope on hemagglutinin head and confers heterosubtypic protection
Nature Communications - H7N9 influenza A virus circulates in poultry but can also infect humans with often fatal outcome. Here, Chen et al. identify a novel nanobody that cross-reacts between H7N9...
rdcu.be
January 9, 2025 at 2:58 PM
2024 is ending ....and we are excited to start our own nanobody discovery campaigns in 2025! 👇👇👇👇
December 30, 2024 at 9:46 PM