Debbie Bangasser
@bangasserlab.bsky.social
Neuroendocrinology & Behavior Lab| 3 parts neuro🧠 science🔬🧪 + 1 part Debbie’s weird hobbies 🐦💃🤿 | Debbie’s pronouns she/her/hers
Reposted by Debbie Bangasser
These are the final IBRO #grant calls for 2025 to help you boost your skills through #neuroscience #training or organize an internship program to support underrepresented students
🧠 Explore these open calls & apply before the deadlines!
👉 https://ibro.org/grants/?tab=open-calls
🧠 Explore these open calls & apply before the deadlines!
👉 https://ibro.org/grants/?tab=open-calls
November 3, 2025 at 1:02 PM
These are the final IBRO #grant calls for 2025 to help you boost your skills through #neuroscience #training or organize an internship program to support underrepresented students
🧠 Explore these open calls & apply before the deadlines!
👉 https://ibro.org/grants/?tab=open-calls
🧠 Explore these open calls & apply before the deadlines!
👉 https://ibro.org/grants/?tab=open-calls
Reposted by Debbie Bangasser
Excited to share our newest project using spatial transcriptomics with novel image analysis approaches to investigate the impact of biological risk factors for Alzheimer's disease (AD) - APOE haplotype, sex, and genomic ancestry - on molecular states in the locus coeruleus (LC 🔵) of the human 🧠.
Got with the times + made a BSky to share our new, large-scale spatial RNAseq study of adult human #locuscoeruleus! Co-1st auth and cryostat wizard @heenadivecha.bsky.social squeezed 85 tissue sections into 43 Visium arrays. (1/8)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Impact of Alzheimer's disease risk factors and local neuromelanin content on the transcriptomic landscape of the human locus coeruleus
The locus coeruleus (LC) is a small noradrenergic nucleus in the dorsal pons that sends projections across the brain regulating sleep, arousal, attention, stress responses, and some forms of cognition...
www.biorxiv.org
October 31, 2025 at 5:24 PM
Excited to share our newest project using spatial transcriptomics with novel image analysis approaches to investigate the impact of biological risk factors for Alzheimer's disease (AD) - APOE haplotype, sex, and genomic ancestry - on molecular states in the locus coeruleus (LC 🔵) of the human 🧠.
Reposted by Debbie Bangasser
Happy to share that the first data paper from my lab is out! We find that developmental exposure to PBDE flame retardants drives persistent and sex specific effects on mast cells in and ex vivo www.sciencedirect.com/science/arti...
Developmental PBDE exposure persistently impairs mast cell function in vivo and drives sex-specific morphological and transcriptional changes in bone marrow–derived mast cells
Polybrominated diphenyl ethers (PBDEs) are synthetic flame retardants once widely used in furniture, electronics, and other consumer products. Althoug…
www.sciencedirect.com
October 31, 2025 at 9:15 PM
Happy to share that the first data paper from my lab is out! We find that developmental exposure to PBDE flame retardants drives persistent and sex specific effects on mast cells in and ex vivo www.sciencedirect.com/science/arti...
From the archives, 8 yrs ago my grad student at the time Kim carved this for our department pumpkin 🎃 carving contest (guess what task she was doing)
October 31, 2025 at 9:49 PM
From the archives, 8 yrs ago my grad student at the time Kim carved this for our department pumpkin 🎃 carving contest (guess what task she was doing)
Halloween 🎃 in the lab
October 31, 2025 at 8:57 PM
Halloween 🎃 in the lab
Two of my lab members were super excited to show me their Halloween costumes today 🤣🤣🤣
I wish my hair was actually that fun
I wish my hair was actually that fun
October 29, 2025 at 11:35 PM
Two of my lab members were super excited to show me their Halloween costumes today 🤣🤣🤣
I wish my hair was actually that fun
I wish my hair was actually that fun
Our 2025-2026 Neuroendocrinology & Behavior Lab crew (most of them). I so honored to work with this brilliant team!!!! 🧠🧬🔬🧫🧪
October 23, 2025 at 12:34 PM
Our 2025-2026 Neuroendocrinology & Behavior Lab crew (most of them). I so honored to work with this brilliant team!!!! 🧠🧬🔬🧫🧪
Reposted by Debbie Bangasser
We've added even more to our Applying to Faculty Jobs 101! Follow the link below to find tips from @drnancypadilla.bsky.social and @moeneuro.bsky.social on everything from where to find job ads, how to advocate for yourself, what goes into a research statement, and more!
Applying for faculty jobs this cycle? Check out our latest special episode! @moeneuro.bsky.social and @drnancypadilla.bsky.social discuss when to apply, important considerations when preparing applications, and more! Listen below!
www.storiesofwin.org/profiles/202...
#AcademicBluesky #NeuroJobs
www.storiesofwin.org/profiles/202...
#AcademicBluesky #NeuroJobs
Applying to faculty jobs 101 — Stories of WiN
This episode features Dr. Monique Smith (Assistant Professor, UCSD) discussing faculty job applications with host Dr. Nancy Padilla-Coreano.
www.storiesofwin.org
October 21, 2025 at 2:24 PM
We've added even more to our Applying to Faculty Jobs 101! Follow the link below to find tips from @drnancypadilla.bsky.social and @moeneuro.bsky.social on everything from where to find job ads, how to advocate for yourself, what goes into a research statement, and more!
Reposted by Debbie Bangasser
Neuroscientists! This is a great opportunity to recognize excellent colleagues for a prize and linked to give a talk at the FENS Forum in 2026! Nominate or apply directly! Deadline: Oct 29th!
ALBA-Elsevier Award for Neuroscience - @network-alba.bsky.social
ALBA-Elsevier Award for Neuroscience - @network-alba.bsky.social
📣 Deadline extended to 29 Oct 2025! The ALBA–Elsevier Award Lecture honours neuroscientists from underrepresented regions (based on Elsevier authorship metrics & journal market share, & past conference speakers).
🏆 Special Lecture at #FENS2026
✅ Must have led own lab ≥5 years
👉🏽 loom.ly/FEG7E-w
🏆 Special Lecture at #FENS2026
✅ Must have led own lab ≥5 years
👉🏽 loom.ly/FEG7E-w
October 16, 2025 at 9:55 AM
Neuroscientists! This is a great opportunity to recognize excellent colleagues for a prize and linked to give a talk at the FENS Forum in 2026! Nominate or apply directly! Deadline: Oct 29th!
ALBA-Elsevier Award for Neuroscience - @network-alba.bsky.social
ALBA-Elsevier Award for Neuroscience - @network-alba.bsky.social
“Alright, Mr. DeMille, I'm ready for my close-up”
This Eastern phoebe was really for the photo shoot.
#birds #BirdsSeenIn2025 #BigDayOfBirding #Atl
This Eastern phoebe was really for the photo shoot.
#birds #BirdsSeenIn2025 #BigDayOfBirding #Atl
October 16, 2025 at 10:46 AM
“Alright, Mr. DeMille, I'm ready for my close-up”
This Eastern phoebe was really for the photo shoot.
#birds #BirdsSeenIn2025 #BigDayOfBirding #Atl
This Eastern phoebe was really for the photo shoot.
#birds #BirdsSeenIn2025 #BigDayOfBirding #Atl
Reposted by Debbie Bangasser
Congratulations to Rebekah Rashford and team, it’s finally out! We tagged early life stress-activated neurons in VTA and found that chromatin those cells was much more open, even into adulthood, and that open CREs predicted greater gene expression in response to stress later in life
rdcu.be/eLa9z
rdcu.be/eLa9z
Persistent open chromatin state in early-life stress-activated cells of the VTA
Scientific Reports - Persistent open chromatin state in early-life stress-activated cells of the VTA
rdcu.be
October 15, 2025 at 5:07 PM
Congratulations to Rebekah Rashford and team, it’s finally out! We tagged early life stress-activated neurons in VTA and found that chromatin those cells was much more open, even into adulthood, and that open CREs predicted greater gene expression in response to stress later in life
rdcu.be/eLa9z
rdcu.be/eLa9z
For #WildlifeWednesday one of my fav species: Yellow-billed cuckoo!!
So elusive! I’ve only seen them a few times.
Taken at Lullwater Preserve #ATL
#birds #BirdsSeenIn2025
So elusive! I’ve only seen them a few times.
Taken at Lullwater Preserve #ATL
#birds #BirdsSeenIn2025
October 8, 2025 at 12:54 PM
For #WildlifeWednesday one of my fav species: Yellow-billed cuckoo!!
So elusive! I’ve only seen them a few times.
Taken at Lullwater Preserve #ATL
#birds #BirdsSeenIn2025
So elusive! I’ve only seen them a few times.
Taken at Lullwater Preserve #ATL
#birds #BirdsSeenIn2025
Reposted by Debbie Bangasser
I’ve been around long enough to remember older children in my primary school who’d contracted polio. It was a scary time— & we placed such hope & trust in science (and the sugar cubes!). A great read ⬇️
The Polio Vaccine Was a Miracle—and We Must Not Forget It
open.substack.com/pub/thebulwa...
The Polio Vaccine Was a Miracle—and We Must Not Forget It
open.substack.com/pub/thebulwa...
The Polio Vaccine Was a Miracle—and We Must Not Forget It
As a polio survivor, I am a dinosaur today. My great hope is that our country’s living memory of the disease ends with my generation.
open.substack.com
October 6, 2025 at 5:42 PM
I’ve been around long enough to remember older children in my primary school who’d contracted polio. It was a scary time— & we placed such hope & trust in science (and the sugar cubes!). A great read ⬇️
The Polio Vaccine Was a Miracle—and We Must Not Forget It
open.substack.com/pub/thebulwa...
The Polio Vaccine Was a Miracle—and We Must Not Forget It
open.substack.com/pub/thebulwa...
Juvenile greater flamingos 🦩!!!!
How can you tell they’re juvenile? They haven’t eaten enough brine shrimp and crustaceans to become pink yet.
Taken in Cabo de Gata 🇪🇸
#EBPS2025 #BirdsSeenIn2025 #birds
How can you tell they’re juvenile? They haven’t eaten enough brine shrimp and crustaceans to become pink yet.
Taken in Cabo de Gata 🇪🇸
#EBPS2025 #BirdsSeenIn2025 #birds
September 30, 2025 at 1:32 PM
Juvenile greater flamingos 🦩!!!!
How can you tell they’re juvenile? They haven’t eaten enough brine shrimp and crustaceans to become pink yet.
Taken in Cabo de Gata 🇪🇸
#EBPS2025 #BirdsSeenIn2025 #birds
How can you tell they’re juvenile? They haven’t eaten enough brine shrimp and crustaceans to become pink yet.
Taken in Cabo de Gata 🇪🇸
#EBPS2025 #BirdsSeenIn2025 #birds
Reposted by Debbie Bangasser
Astrocytes functionally integrate multiple synapses via specialized leaflet domains
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Astrocytes functionally integrate multiple synapses via specialized leaflet domains
Volumetric high-resolution electron microscopy reveals thin astrocyte leaflets form
gap-junction-interconnected domains that contain minuscule endoplasmic reticulum saccules
and enwrap synapses in clu...
www.cell.com
September 25, 2025 at 10:20 AM
Astrocytes functionally integrate multiple synapses via specialized leaflet domains
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Reposted by Debbie Bangasser
Check out our new work from former undergrad Akash Shanmugam and team in Addiction Neuroscience directly comparing the rewarding and analgesic potencies of morphine and methadone. www.sciencedirect.com/science/arti...
Methadone and morphine have equivalent analgesic but not reward potency in female mice
Morphine is a potent opioid analgesic but carries high abuse potential. Some evidence indicates that the opioid methadone, used in maintenance therapy…
www.sciencedirect.com
September 24, 2025 at 7:31 PM
Check out our new work from former undergrad Akash Shanmugam and team in Addiction Neuroscience directly comparing the rewarding and analgesic potencies of morphine and methadone. www.sciencedirect.com/science/arti...
Amazing session at #EBPS2025 on sex differences in SUD, mood, & AD. @christinadalla.bsky.social organized a great group.
September 20, 2025 at 3:04 PM
Amazing session at #EBPS2025 on sex differences in SUD, mood, & AD. @christinadalla.bsky.social organized a great group.
Agreed. Another tour-de-force talk from John! Love the new directions.
A brilliant keynote today by @jfcryan.bsky.social at the EBPS meeting on how the gut shapes behavior, including striking causal evidence for microbiome’s role in social behaviors. A masterclass of body-brain complexity! & with an impressive depth of data and the right dose of humor!
September 20, 2025 at 9:40 AM
Agreed. Another tour-de-force talk from John! Love the new directions.
Reposted by Debbie Bangasser
We showed previously that chemogenetic activation of the LC rescues spatial reversal learning in the TgF344-AD rat. New paper follows up and reports that optogenetic stimulation of LC terminals in CA1 also rescues cognitive deficits in 3xTg mouse model of AD. link.springer.com/article/10.1...
Photostimulation of locus coeruleus CA1 catecholaminergic terminals reversed Spatial memory impairment in an alzheimer’s disease mouse model - Psychopharmacology
Rationale One of the earliest changes associated with Alzheimer’s disease (AD) is the loss of catecholaminergic terminals in the cortex and hippocampus originating from the Locus Coeruleus (LC). This ...
link.springer.com
September 12, 2025 at 6:50 PM
We showed previously that chemogenetic activation of the LC rescues spatial reversal learning in the TgF344-AD rat. New paper follows up and reports that optogenetic stimulation of LC terminals in CA1 also rescues cognitive deficits in 3xTg mouse model of AD. link.springer.com/article/10.1...
Reposted by Debbie Bangasser
A new 🔥 Hot Topic 🔥 from @kundakoviclab.bsky.social is out now in @npp-journal.bsky.social
Thrilled to share our Hot Topics article just published @npp-journal.bsky.social :
"Leveraging high-resolution brain imaging & (epi)genomic approaches to improve women’s mental health"
Always huge pleasure to work w/ @cogneuroend.bsky.social on revolutionizing #WomensMentalHealth 🔥
rdcu.be/eCy6i
"Leveraging high-resolution brain imaging & (epi)genomic approaches to improve women’s mental health"
Always huge pleasure to work w/ @cogneuroend.bsky.social on revolutionizing #WomensMentalHealth 🔥
rdcu.be/eCy6i
Leveraging high-resolution brain imaging and (epi)genomic approaches to improve women’s mental health
Neuropsychopharmacology - Leveraging high-resolution brain imaging and (epi)genomic approaches to improve women’s mental health
rdcu.be
August 27, 2025 at 7:37 PM
A new 🔥 Hot Topic 🔥 from @kundakoviclab.bsky.social is out now in @npp-journal.bsky.social
Reposted by Debbie Bangasser
Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long-lasting behavioral abnormalities
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long-lasting behavioral abnormalities
Prenatal stress (PNS) is a well-established risk factor for psychiatric disorders, yet the underlying neurobiological mechanisms remain unclear. Here,…
www.sciencedirect.com
August 26, 2025 at 9:55 AM
Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long-lasting behavioral abnormalities
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Wrapped up my last of 6 tenure & promotion letters for the season. Absolutely, floored by the accomplishments of my colleagues especially given the pandemic. They persisted & made great discoveries that will improve human 🧠 health! Can’t wait to see the position update posts this spring
a cartoon llama holding a microphone with the words and that 's that
ALT: a cartoon llama holding a microphone with the words and that 's that
media.tenor.com
August 18, 2025 at 5:36 PM
Wrapped up my last of 6 tenure & promotion letters for the season. Absolutely, floored by the accomplishments of my colleagues especially given the pandemic. They persisted & made great discoveries that will improve human 🧠 health! Can’t wait to see the position update posts this spring
Reposted by Debbie Bangasser
I still get chills
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
August 10, 2025 at 6:23 PM
I still get chills
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...