Alessandro Nascimento
@asnascimento.bsky.social
Associate Professor @ University of Sao Paulo. Structural biologist. Protein crystallographer. Interested in protein-ligand interactions and modeling
Interesting….
Google presents PaperBanana
Automating Academic Illustration for AI Scientists
huggingface.co/papers/2601....
Automating Academic Illustration for AI Scientists
huggingface.co/papers/2601....
February 3, 2026 at 9:08 PM
Interesting….
Thought of the day. From Richard Feynman @proffeynman.bsky.social in “Surely you’re joking, Mr Feynman!”
January 21, 2026 at 5:59 PM
Thought of the day. From Richard Feynman @proffeynman.bsky.social in “Surely you’re joking, Mr Feynman!”
This is something I've been thinking about for a couple of years now. Let's do better science and it doesn't (necessarily) mean publishing tons of papers....
I’m going to halve my publication output. You should consider slow science, too
If we don’t slow down, the research enterprise is going to crash, argues Adrian Barnett.
www.nature.com
January 19, 2026 at 12:56 PM
This is something I've been thinking about for a couple of years now. Let's do better science and it doesn't (necessarily) mean publishing tons of papers....
🙋♂️🙋♂️🙋♂️
January 8, 2026 at 3:54 PM
🙋♂️🙋♂️🙋♂️
Not wrong….
January 7, 2026 at 9:48 PM
Not wrong….
This is what acknowledgments are for!
PS: the paper is also super cool!
Paper: www.pnas.org/doi/pdf/10.1...
PS: the paper is also super cool!
Paper: www.pnas.org/doi/pdf/10.1...
January 7, 2026 at 6:11 PM
This is what acknowledgments are for!
PS: the paper is also super cool!
Paper: www.pnas.org/doi/pdf/10.1...
PS: the paper is also super cool!
Paper: www.pnas.org/doi/pdf/10.1...
So true….
January 3, 2026 at 11:28 PM
So true….
😅😅😅😅
I love this!
I love this!
January 1, 2026 at 10:16 PM
😅😅😅😅
I love this!
I love this!
😅😅😅
December 22, 2025 at 11:33 AM
😅😅😅
Reposted by Alessandro Nascimento
Are quantum computers the next revolution in drug discovery?
Please, take some time to read this great paper from my very good friend Mohammad Ghazi Vakili and supervised by the visionary @aspuru.bsky.social !
PS: I loved the cover image!
Please, take some time to read this great paper from my very good friend Mohammad Ghazi Vakili and supervised by the visionary @aspuru.bsky.social !
PS: I loved the cover image!
Excited to share that our January paper, “Quantum-computing-enhanced algorithm unveils potential KRAS inhibitors” has been recognized by Nature Biotechnology as one of the journal’s Top 10 research articles of 2025, and selected as the December cover article.
📜 www.nature.com/articles/s41...
[1/9]
📜 www.nature.com/articles/s41...
[1/9]
December 15, 2025 at 5:30 PM
Are quantum computers the next revolution in drug discovery?
Please, take some time to read this great paper from my very good friend Mohammad Ghazi Vakili and supervised by the visionary @aspuru.bsky.social !
PS: I loved the cover image!
Please, take some time to read this great paper from my very good friend Mohammad Ghazi Vakili and supervised by the visionary @aspuru.bsky.social !
PS: I loved the cover image!
Reposted by Alessandro Nascimento
If you are an AI researcher (in academia or industry) outside of Canada and willing to move to Canada, there is a great opportunity: www.canada.ca/en/impact-pl... please get in touch! We would love to hear from people who apply AI in health and neuroscience too!
December 10, 2025 at 5:16 PM
If you are an AI researcher (in academia or industry) outside of Canada and willing to move to Canada, there is a great opportunity: www.canada.ca/en/impact-pl... please get in touch! We would love to hear from people who apply AI in health and neuroscience too!
Reposted by Alessandro Nascimento
University is only fee free in a small handful of countries. Source: buff.ly/PAuDqrF
December 7, 2025 at 4:30 PM
University is only fee free in a small handful of countries. Source: buff.ly/PAuDqrF
Reposted by Alessandro Nascimento
Picard management tip: If you only play to your strengths you may look competent but ultimately you will stagnate. Play to your weaknesses as well. Improve with practice. There is so much more to learn.
December 7, 2025 at 3:04 PM
Picard management tip: If you only play to your strengths you may look competent but ultimately you will stagnate. Play to your weaknesses as well. Improve with practice. There is so much more to learn.
Reposted by Alessandro Nascimento
Now in Science: Cracking quantum chemistry with quantum computers - a new perspective article by Philipp Schleich and @aspuru.bsky.social
🔗 www.science.org/doi/epdf/10....
[1/4]
🔗 www.science.org/doi/epdf/10....
[1/4]
Cracking chemistry with quantum simulations
Dynamic characteristics of complex chemical reactions can be accurately modeled by a quantum computer
www.science.org
December 5, 2025 at 9:04 PM
Now in Science: Cracking quantum chemistry with quantum computers - a new perspective article by Philipp Schleich and @aspuru.bsky.social
🔗 www.science.org/doi/epdf/10....
[1/4]
🔗 www.science.org/doi/epdf/10....
[1/4]
Reposted by Alessandro Nascimento
What coding with an LLM feels like sometimes.
December 3, 2025 at 9:29 AM
What coding with an LLM feels like sometimes.
Reposted by Alessandro Nascimento
Picard management tip: If they know their jobs, leave them alone. If they don't, help them learn.
November 11, 2025 at 7:22 PM
Picard management tip: If they know their jobs, leave them alone. If they don't, help them learn.
Reposted by Alessandro Nascimento
🚨 Three PDRA posts @imperialchemistry.bsky.social with me + collaborators to transform materials discovery.
Focus:
💻 Comp Chem
🤖 AI in Chem
🧠 Neurosymbolic Learning
🗓️ Apply by 11 Nov 2025
🔗 jobs.ac.uk/job/DPB378 (click "Apply" to find individual post details)
#chemsky #compchem #chempostdoc
Focus:
💻 Comp Chem
🤖 AI in Chem
🧠 Neurosymbolic Learning
🗓️ Apply by 11 Nov 2025
🔗 jobs.ac.uk/job/DPB378 (click "Apply" to find individual post details)
#chemsky #compchem #chempostdoc
Research Associate positions in Computational Chemistry, AI in Chemistry, and in Neurosymbolic Learning for Chemistry at Imperial College London
An opportunity for an academic position as a Research Associate positions in Computational Chemistry, AI in Chemistry, and in Neurosymbolic Learning for Chemistry is available, as advertised on jobs.a...
jobs.ac.uk
October 17, 2025 at 8:39 AM
🚨 Three PDRA posts @imperialchemistry.bsky.social with me + collaborators to transform materials discovery.
Focus:
💻 Comp Chem
🤖 AI in Chem
🧠 Neurosymbolic Learning
🗓️ Apply by 11 Nov 2025
🔗 jobs.ac.uk/job/DPB378 (click "Apply" to find individual post details)
#chemsky #compchem #chempostdoc
Focus:
💻 Comp Chem
🤖 AI in Chem
🧠 Neurosymbolic Learning
🗓️ Apply by 11 Nov 2025
🔗 jobs.ac.uk/job/DPB378 (click "Apply" to find individual post details)
#chemsky #compchem #chempostdoc
Reposted by Alessandro Nascimento
New paper out in PNAS Nexus!
Molecules aren’t flat — so why should our models be?🧬
Our latest work "Stereochemistry-aware string-based molecular generation,” explores how considering stereochemistry changes the way machine learning models design molecules.
Link: doi.org/10.1093/pnas...
[1/4]
Molecules aren’t flat — so why should our models be?🧬
Our latest work "Stereochemistry-aware string-based molecular generation,” explores how considering stereochemistry changes the way machine learning models design molecules.
Link: doi.org/10.1093/pnas...
[1/4]
Stereochemistry-aware string-based molecular generation
Abstract. This study investigates the impact of incorporating stereochemical information, a crucial aspect of computational drug discovery and materials de
doi.org
November 5, 2025 at 6:01 PM
New paper out in PNAS Nexus!
Molecules aren’t flat — so why should our models be?🧬
Our latest work "Stereochemistry-aware string-based molecular generation,” explores how considering stereochemistry changes the way machine learning models design molecules.
Link: doi.org/10.1093/pnas...
[1/4]
Molecules aren’t flat — so why should our models be?🧬
Our latest work "Stereochemistry-aware string-based molecular generation,” explores how considering stereochemistry changes the way machine learning models design molecules.
Link: doi.org/10.1093/pnas...
[1/4]
Reposted by Alessandro Nascimento
Last call - open til Oct 30!
Are you excited about #MachineLearning and developing new architectures for Molecular Biology? Joint us for the next chapter of BioEmu at @msftresearch.bsky.social AI for Science - Berlin DE or Cambridge UK.
aka.ms/bioemu-ml
Are you excited about #MachineLearning and developing new architectures for Molecular Biology? Joint us for the next chapter of BioEmu at @msftresearch.bsky.social AI for Science - Berlin DE or Cambridge UK.
aka.ms/bioemu-ml
Search Jobs | Microsoft Careers
aka.ms
October 27, 2025 at 6:58 PM
Last call - open til Oct 30!
Are you excited about #MachineLearning and developing new architectures for Molecular Biology? Joint us for the next chapter of BioEmu at @msftresearch.bsky.social AI for Science - Berlin DE or Cambridge UK.
aka.ms/bioemu-ml
Are you excited about #MachineLearning and developing new architectures for Molecular Biology? Joint us for the next chapter of BioEmu at @msftresearch.bsky.social AI for Science - Berlin DE or Cambridge UK.
aka.ms/bioemu-ml
😮😮😮😮
Baker lab builds a calcium channel entirely from scratch. This should enable cellular behaviors to be altered in entirely new ways.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Bottom-up design of Ca2+ channels from defined selectivity filter geometry - Nature
De novo design of Ca2+ channels with ion selectivity that can assemble appropriately and mediate Ca2+ conductance when expressed in cells is described.
www.nature.com
October 25, 2025 at 10:24 PM
😮😮😮😮
Reposted by Alessandro Nascimento
We’re Hiring Professor (all ranks) in Synthetic Biology and AI-Enabled Biodesign at the School of Biological and Health Systems Engineering, Arizona State University.📍 Tempe, Arizona
Apply here: apply.interfolio.com/175856
Apply here: apply.interfolio.com/175856
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 24, 2025 at 4:11 PM
We’re Hiring Professor (all ranks) in Synthetic Biology and AI-Enabled Biodesign at the School of Biological and Health Systems Engineering, Arizona State University.📍 Tempe, Arizona
Apply here: apply.interfolio.com/175856
Apply here: apply.interfolio.com/175856
Reposted by Alessandro Nascimento
Opportunity for computational chemist at Inductive Bio (USA: New York City, San Francisco, or Boston) #CompChem #cheminformatics #ADMET #ChemJobs #chemsky 🧪
www.inductive.bio/careers?ashb...
www.inductive.bio/careers?ashb...
We're Hiring | Inductive Bio
Inductive Bio is accelerating small molecule drug discovery with cutting-edge AI and proprietary data. Join our fast-growing team backed by top investors like a16z and Lux.
www.inductive.bio
October 23, 2025 at 6:14 AM
Opportunity for computational chemist at Inductive Bio (USA: New York City, San Francisco, or Boston) #CompChem #cheminformatics #ADMET #ChemJobs #chemsky 🧪
www.inductive.bio/careers?ashb...
www.inductive.bio/careers?ashb...
Reposted by Alessandro Nascimento
Opportunity in computational structural biology at ISTA (Vienna Austria) duration: 5 years with possibility of permanent contract #StructBiol #cryoEM #cryoET #chemsky 🧪
ista.ac.at/en/job/tenur...
ista.ac.at/en/job/tenur...
Tenure-based Research Staff Scientist Position in Computational Structural Biology
ISTA (www.ista.ac.at) is seeking a highly skilled Staff Scientist in Computational Structural Biology to support and advance the Institute’s structural biology research through the development and imp...
ista.ac.at
October 16, 2025 at 6:30 AM
Opportunity in computational structural biology at ISTA (Vienna Austria) duration: 5 years with possibility of permanent contract #StructBiol #cryoEM #cryoET #chemsky 🧪
ista.ac.at/en/job/tenur...
ista.ac.at/en/job/tenur...