Arthur Lensen
@arthurlensen.bsky.social
PhD student in Enninga lab, Institut Pasteur. Shigella, microscopy and cytoskeleton 🦠🔬🧫
Reposted by Arthur Lensen
Time for some insights into our latest #preprint
Using cryo–electron tomography, we peeked inside different #Mtuberculosis strains, and a couple of other mycobacteria.🧐 Surprise: some species, especially the host-adapted ones, build intracytoplasmic membranes (we call them MIMs)! 🦠
Using cryo–electron tomography, we peeked inside different #Mtuberculosis strains, and a couple of other mycobacteria.🧐 Surprise: some species, especially the host-adapted ones, build intracytoplasmic membranes (we call them MIMs)! 🦠
🦠 Mycobacteria aren't just tough, they're interior designers! 🦠 Check out our latest #preprint 🚨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity 🤫
Thread coming soon!
Thread coming soon!
Nitrate-responsive Mycobacterial Intracytoplasmic Membranes dampen Inflammation during Mycobacterium tuberculosis Infection https://www.biorxiv.org/content/10.1101/2025.09.17.676823v1
September 22, 2025 at 7:25 PM
Time for some insights into our latest #preprint
Using cryo–electron tomography, we peeked inside different #Mtuberculosis strains, and a couple of other mycobacteria.🧐 Surprise: some species, especially the host-adapted ones, build intracytoplasmic membranes (we call them MIMs)! 🦠
Using cryo–electron tomography, we peeked inside different #Mtuberculosis strains, and a couple of other mycobacteria.🧐 Surprise: some species, especially the host-adapted ones, build intracytoplasmic membranes (we call them MIMs)! 🦠
After years of hard work and months of growing MTB @camimille.bsky.social submitted her story ! Check this out if you wanna discover new intrabacterial structures and their function ! 🦠🔬✨
🦠 Mycobacteria aren't just tough, they're interior designers! 🦠 Check out our latest #preprint 🚨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity 🤫
Thread coming soon!
Thread coming soon!
Nitrate-responsive Mycobacterial Intracytoplasmic Membranes dampen Inflammation during Mycobacterium tuberculosis Infection https://www.biorxiv.org/content/10.1101/2025.09.17.676823v1
September 18, 2025 at 5:52 PM
After years of hard work and months of growing MTB @camimille.bsky.social submitted her story ! Check this out if you wanna discover new intrabacterial structures and their function ! 🦠🔬✨
Very happy to have participated in #ETOX2025 ! Very nice science, amazing crowd and wonderful place ! I was happy to present a poster of my work to a lot of old and new friends and colleagues. Thanks to the organizer for all their work and I hope to come back in two years !
July 8, 2025 at 10:22 PM
Very happy to have participated in #ETOX2025 ! Very nice science, amazing crowd and wonderful place ! I was happy to present a poster of my work to a lot of old and new friends and colleagues. Thanks to the organizer for all their work and I hope to come back in two years !
Reposted by Arthur Lensen
A massive thank you to all the incredible participants and speakers who made ETOX 2025 in the Basque Country an unforgettable event! Your insights, discussions, and passion for bacterial protein toxins have truly advanced the field. We're already looking forward to next time! #ETOX2025
July 6, 2025 at 6:30 PM
A massive thank you to all the incredible participants and speakers who made ETOX 2025 in the Basque Country an unforgettable event! Your insights, discussions, and passion for bacterial protein toxins have truly advanced the field. We're already looking forward to next time! #ETOX2025
Reposted by Arthur Lensen
Zoom into a human cell infected by Shigella, the bacteria behind dysentery. Using cryo-EM, @leaswistak.bsky.social and team revealed how it pierces cells with molecular syringes. Stunning science at the nanoscale.
@enningalab.bsky.social @jytinevez.bsky.social @nanoimaging.bsky.social
#CryoEM
@enningalab.bsky.social @jytinevez.bsky.social @nanoimaging.bsky.social
#CryoEM
May 26, 2025 at 9:39 AM
Zoom into a human cell infected by Shigella, the bacteria behind dysentery. Using cryo-EM, @leaswistak.bsky.social and team revealed how it pierces cells with molecular syringes. Stunning science at the nanoscale.
@enningalab.bsky.social @jytinevez.bsky.social @nanoimaging.bsky.social
#CryoEM
@enningalab.bsky.social @jytinevez.bsky.social @nanoimaging.bsky.social
#CryoEM
Reposted by Arthur Lensen
How do intracellular #bacteria breach vacuoles to enter the host cytosol? @leaswistak.bsky.social @matthijnvos.bsky.social @enningalab.bsky.social &co show that #Shigella uses its T3SS system to damage endomembranes via mechanoporation to initiate cytosolic access @plosbiology.org 🧪 plos.io/4jXrr9Z
May 6, 2025 at 12:46 PM
How do intracellular #bacteria breach vacuoles to enter the host cytosol? @leaswistak.bsky.social @matthijnvos.bsky.social @enningalab.bsky.social &co show that #Shigella uses its T3SS system to damage endomembranes via mechanoporation to initiate cytosolic access @plosbiology.org 🧪 plos.io/4jXrr9Z
Reposted by Arthur Lensen
1/5 🚀 Excited to share our latest preprint from: 𝗦𝗶𝗥-𝗫𝗔𝗰𝘁𝗶𝗻: 𝗔 𝗳𝗹𝘂𝗼𝗿𝗲𝘀𝗰𝗲𝗻𝘁 𝗽𝗿𝗼𝗯𝗲 𝗳𝗼𝗿 𝗶𝗺𝗮𝗴𝗶𝗻𝗴 𝗮𝗰𝘁𝗶𝗻 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 𝗶𝗻 𝗹𝗶𝘃𝗲 𝗰𝗲𝗹𝗹𝘀 on #bioRxiv!
www.biorxiv.org/content/10.1...
#JohnssonLab and #ArndtLab with valued collaborators
www.biorxiv.org/content/10.1...
#JohnssonLab and #ArndtLab with valued collaborators
February 6, 2025 at 8:00 PM
1/5 🚀 Excited to share our latest preprint from: 𝗦𝗶𝗥-𝗫𝗔𝗰𝘁𝗶𝗻: 𝗔 𝗳𝗹𝘂𝗼𝗿𝗲𝘀𝗰𝗲𝗻𝘁 𝗽𝗿𝗼𝗯𝗲 𝗳𝗼𝗿 𝗶𝗺𝗮𝗴𝗶𝗻𝗴 𝗮𝗰𝘁𝗶𝗻 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 𝗶𝗻 𝗹𝗶𝘃𝗲 𝗰𝗲𝗹𝗹𝘀 on #bioRxiv!
www.biorxiv.org/content/10.1...
#JohnssonLab and #ArndtLab with valued collaborators
www.biorxiv.org/content/10.1...
#JohnssonLab and #ArndtLab with valued collaborators
No one mourns the Wicked ! Some 🟢Elphaba🟢 colored actin and cytosolic 🟣Glinda magic🟣.
Steer all this with 🔵 Hoescht, Shigella and 🟡 Rab35 (PMID : 38568808 😉) and you get these sparkling cells, perfect for #FluorescenceFriday
Steer all this with 🔵 Hoescht, Shigella and 🟡 Rab35 (PMID : 38568808 😉) and you get these sparkling cells, perfect for #FluorescenceFriday
January 24, 2025 at 8:40 AM
No one mourns the Wicked ! Some 🟢Elphaba🟢 colored actin and cytosolic 🟣Glinda magic🟣.
Steer all this with 🔵 Hoescht, Shigella and 🟡 Rab35 (PMID : 38568808 😉) and you get these sparkling cells, perfect for #FluorescenceFriday
Steer all this with 🔵 Hoescht, Shigella and 🟡 Rab35 (PMID : 38568808 😉) and you get these sparkling cells, perfect for #FluorescenceFriday
Reposted by Arthur Lensen
The Institut Pasteur has decided to leave X (formerly Twitter) to join BlueSky! 🦋
The Institut Pasteur made this decision due to several serious issues observed on the X platform since its acquisition. Join us here to continue advocating for science. www.pasteur.fr/en/home/pres...
The Institut Pasteur made this decision due to several serious issues observed on the X platform since its acquisition. Join us here to continue advocating for science. www.pasteur.fr/en/home/pres...
Institut Pasteur decides to leave X
The Institut Pasteur, a research organization which for more than 130 years has been committed to tackling infectious diseases, sharing knowledge and defending science, has decided to leave X because ...
www.pasteur.fr
January 16, 2025 at 9:18 AM
The Institut Pasteur has decided to leave X (formerly Twitter) to join BlueSky! 🦋
The Institut Pasteur made this decision due to several serious issues observed on the X platform since its acquisition. Join us here to continue advocating for science. www.pasteur.fr/en/home/pres...
The Institut Pasteur made this decision due to several serious issues observed on the X platform since its acquisition. Join us here to continue advocating for science. www.pasteur.fr/en/home/pres...
Reposted by Arthur Lensen
Happy to share our latest preprint on dormant #Salmonella and the role of SifA for intravacuolar nutrition! Thanks to all the co-authors!
SifA-mediated Remodeling of the Salmonella-Containing Vacuole Prevents Bacterial Dormancy by Promoting Nutrient Accessibility https://www.biorxiv.org/content/10.1101/2025.01.08.631959v1
January 9, 2025 at 9:37 AM
Happy to share our latest preprint on dormant #Salmonella and the role of SifA for intravacuolar nutrition! Thanks to all the co-authors!
Reposted by Arthur Lensen
You want to learn about microbiology from a fantastic lineup of speakers on a beautiful Greek island? PhD students apply now for the @EMBO | @FEBSnews Lecture Course The New Microbiology!
Registration: 1 Apr 2025
Course: 03 – 11 Sep 2025 | Spetses, Greece
meetings.embo.org/event/25-new...
Registration: 1 Apr 2025
Course: 03 – 11 Sep 2025 | Spetses, Greece
meetings.embo.org/event/25-new...
December 16, 2024 at 8:43 AM
You want to learn about microbiology from a fantastic lineup of speakers on a beautiful Greek island? PhD students apply now for the @EMBO | @FEBSnews Lecture Course The New Microbiology!
Registration: 1 Apr 2025
Course: 03 – 11 Sep 2025 | Spetses, Greece
meetings.embo.org/event/25-new...
Registration: 1 Apr 2025
Course: 03 – 11 Sep 2025 | Spetses, Greece
meetings.embo.org/event/25-new...
Reposted by Arthur Lensen
Excited to share our study led by @SakenovaNazgul! We used chemical genetics to identify and understand cross-resistance & collateral-sensitivity (CS) between antibiotics and reduced AMR development with CS drug pairs @embl.org with @camille_goemans @EPFL_en www.nature.com/articles/s41...
Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics - Nature Microbiology
Resistance to one antibiotic can make bacteria resistant or sensitive to another antibiotic, opening paths for combinatorial treatments. This study presents an approach to systematically discover and ...
www.nature.com
December 2, 2024 at 10:33 AM
Excited to share our study led by @SakenovaNazgul! We used chemical genetics to identify and understand cross-resistance & collateral-sensitivity (CS) between antibiotics and reduced AMR development with CS drug pairs @embl.org with @camille_goemans @EPFL_en www.nature.com/articles/s41...