David Albesa
@davidalbesa.bsky.social
Interested in structure-function studies of bacterial protein toxins (http://albesalab.org)
Pinned
David Albesa
@davidalbesa.bsky.social
· Jun 6
New research reveals the mode of action of the Pseudomonas aeruginosa #T6SS Tse4 toxin. Tse4 forms ion-selective, voltage-sensitive channels in bacterial membranes, coupling cell depolarization with K⁺ efflux. This highlights a key antibacterial strategy. #PFPsky
doi.org/10.1371/jour...
doi.org/10.1371/jour...
Reposted by David Albesa
I am thrilled to share with you the outcome of the first collaboration with Albesa-Jove's lab (albesalab.org), in which we characterised the molecular mechanisms underlying the binding of a T6SS adaptor-effector pair in P. putida, Tap3–Tke5. (🧵1/9). Read the full paper here: doi.org/10.1038/s443...
January 14, 2026 at 11:38 AM
I am thrilled to share with you the outcome of the first collaboration with Albesa-Jove's lab (albesalab.org), in which we characterised the molecular mechanisms underlying the binding of a T6SS adaptor-effector pair in P. putida, Tap3–Tke5. (🧵1/9). Read the full paper here: doi.org/10.1038/s443...
Reposted by David Albesa
We've got ISSUES. Literally.
We scraped >100k special issues & over 1 million articles to bring you a PISS-poor paper. We quantify just how many excess papers are published by guest editors abusing special issues to boost their CVs. How bad is it & what can we do?
arxiv.org/abs/2601.07563
A 🧵 1/n
We scraped >100k special issues & over 1 million articles to bring you a PISS-poor paper. We quantify just how many excess papers are published by guest editors abusing special issues to boost their CVs. How bad is it & what can we do?
arxiv.org/abs/2601.07563
A 🧵 1/n
January 13, 2026 at 8:27 AM
We've got ISSUES. Literally.
We scraped >100k special issues & over 1 million articles to bring you a PISS-poor paper. We quantify just how many excess papers are published by guest editors abusing special issues to boost their CVs. How bad is it & what can we do?
arxiv.org/abs/2601.07563
A 🧵 1/n
We scraped >100k special issues & over 1 million articles to bring you a PISS-poor paper. We quantify just how many excess papers are published by guest editors abusing special issues to boost their CVs. How bad is it & what can we do?
arxiv.org/abs/2601.07563
A 🧵 1/n
Reposted by David Albesa
We are starting 2026 by looking for candidates to apply for the Junta de Andalucía PhD fellowship. If you are interested in bacterial secretion systems and molecular biology, get in touch. More info about our work: personal.us.es/pbguzman/ & regarding the call www.investigacion.us.es/convocatoria...
January 4, 2026 at 6:50 PM
We are starting 2026 by looking for candidates to apply for the Junta de Andalucía PhD fellowship. If you are interested in bacterial secretion systems and molecular biology, get in touch. More info about our work: personal.us.es/pbguzman/ & regarding the call www.investigacion.us.es/convocatoria...
Reposted by David Albesa
Our paper, describing how the T6SSs of P. putida shape the tomato rhizosphere, is now in its final format in @isme-microbes.bsky.social ISME Communications. If you'd like to learn more, here is a thread (1/11) or read the Article doi.org/10.1093/isme....
October 6, 2025 at 6:22 PM
Our paper, describing how the T6SSs of P. putida shape the tomato rhizosphere, is now in its final format in @isme-microbes.bsky.social ISME Communications. If you'd like to learn more, here is a thread (1/11) or read the Article doi.org/10.1093/isme....
Reposted by David Albesa
Thrilled to share that two of our papers with @jrpenades.bsky.social & GoogleDeepMind
are now out in @cellpress.bsky.social
1️⃣Microbial piracy: tinyurl.com/yvf6t3b3
2️⃣AI co-scientist mirrors experimental science: tinyurl.com/2dym92kj
@imperialcollegeldn.bsky.social
@imperiallifesci.bsky.social
are now out in @cellpress.bsky.social
1️⃣Microbial piracy: tinyurl.com/yvf6t3b3
2️⃣AI co-scientist mirrors experimental science: tinyurl.com/2dym92kj
@imperialcollegeldn.bsky.social
@imperiallifesci.bsky.social
September 9, 2025 at 3:06 PM
Thrilled to share that two of our papers with @jrpenades.bsky.social & GoogleDeepMind
are now out in @cellpress.bsky.social
1️⃣Microbial piracy: tinyurl.com/yvf6t3b3
2️⃣AI co-scientist mirrors experimental science: tinyurl.com/2dym92kj
@imperialcollegeldn.bsky.social
@imperiallifesci.bsky.social
are now out in @cellpress.bsky.social
1️⃣Microbial piracy: tinyurl.com/yvf6t3b3
2️⃣AI co-scientist mirrors experimental science: tinyurl.com/2dym92kj
@imperialcollegeldn.bsky.social
@imperiallifesci.bsky.social
Reposted by David Albesa
A bit late but it has been a fantastic ETOX25 conference organized by @pbernalt6ss.bsky.social and @davidalbesa.bsky.social A fantastic opportunity for @casandratan.bsky.social from @fillouxlab.bsky.social to attend and to reunite a whole crew of Imperial College London Alumni.
August 4, 2025 at 1:39 PM
A bit late but it has been a fantastic ETOX25 conference organized by @pbernalt6ss.bsky.social and @davidalbesa.bsky.social A fantastic opportunity for @casandratan.bsky.social from @fillouxlab.bsky.social to attend and to reunite a whole crew of Imperial College London Alumni.
📢 Job alert! The Structural Microbiology Laboratory (albesalab.org) has two new openings! We are looking for a PhD student and a Research Technician to join our team.
Project: "Structure-function studies of Type VI secretion system toxins".
www.biofisika.org/en/join-us
Apply before 30th September
Project: "Structure-function studies of Type VI secretion system toxins".
www.biofisika.org/en/join-us
Apply before 30th September
Albesa Lab – Structural Microbiology Laboratory
albesalab.org
August 7, 2025 at 8:03 AM
📢 Job alert! The Structural Microbiology Laboratory (albesalab.org) has two new openings! We are looking for a PhD student and a Research Technician to join our team.
Project: "Structure-function studies of Type VI secretion system toxins".
www.biofisika.org/en/join-us
Apply before 30th September
Project: "Structure-function studies of Type VI secretion system toxins".
www.biofisika.org/en/join-us
Apply before 30th September
Reposted by David Albesa
Last week was a fantastic opportunity for @lucasceseti.bsky.social to share his work on Xanthomonas and Dicty at #ETOX25 🦠
The Basque Country was the place to hear great science on toxins🤩
The Basque Country was the place to hear great science on toxins🤩
July 8, 2025 at 2:56 PM
Last week was a fantastic opportunity for @lucasceseti.bsky.social to share his work on Xanthomonas and Dicty at #ETOX25 🦠
The Basque Country was the place to hear great science on toxins🤩
The Basque Country was the place to hear great science on toxins🤩
Reposted by David Albesa
We absolutely had a great time discussing about toxins, effectors and secretion systems. It's amazing how life always finds a way to overcome obstacles. Thank you @pbernalt6ss.bsky.social and @davidalbesa.bsky.social for organising and giving us the opportunity to share our work!
Last week was a fantastic opportunity for @lucasceseti.bsky.social to share his work on Xanthomonas and Dicty at #ETOX25 🦠
The Basque Country was the place to hear great science on toxins🤩
The Basque Country was the place to hear great science on toxins🤩
July 9, 2025 at 7:44 AM
We absolutely had a great time discussing about toxins, effectors and secretion systems. It's amazing how life always finds a way to overcome obstacles. Thank you @pbernalt6ss.bsky.social and @davidalbesa.bsky.social for organising and giving us the opportunity to share our work!
Reposted by David Albesa
The cryo-EM structure of an adaptor-effector complex reveals the mechanism of a widespread pore-forming toxin family https://www.biorxiv.org/content/10.1101/2025.07.04.663240v1
July 7, 2025 at 8:17 PM
The cryo-EM structure of an adaptor-effector complex reveals the mechanism of a widespread pore-forming toxin family https://www.biorxiv.org/content/10.1101/2025.07.04.663240v1
A massive thank you to all the incredible participants and speakers who made ETOX 2025 in the Basque Country an unforgettable event! Your insights, discussions, and passion for bacterial protein toxins have truly advanced the field. We're already looking forward to next time! #ETOX2025
July 6, 2025 at 6:30 PM
A massive thank you to all the incredible participants and speakers who made ETOX 2025 in the Basque Country an unforgettable event! Your insights, discussions, and passion for bacterial protein toxins have truly advanced the field. We're already looking forward to next time! #ETOX2025
Reposted by David Albesa
Picos de Europa was great!
July 6, 2025 at 7:00 AM
Picos de Europa was great!
Reposted by David Albesa
It's a wrap! Thank you
@davidalbesa.bsky.social @pbernalt6ss.bsky.social for organizing such an amazing conference and giving me the opportunity to present my PhD work😁 #ETOX2025
@davidalbesa.bsky.social @pbernalt6ss.bsky.social for organizing such an amazing conference and giving me the opportunity to present my PhD work😁 #ETOX2025
July 5, 2025 at 9:19 PM
It's a wrap! Thank you
@davidalbesa.bsky.social @pbernalt6ss.bsky.social for organizing such an amazing conference and giving me the opportunity to present my PhD work😁 #ETOX2025
@davidalbesa.bsky.social @pbernalt6ss.bsky.social for organizing such an amazing conference and giving me the opportunity to present my PhD work😁 #ETOX2025
Reposted by David Albesa
Check out our latest preprint! We show that the same antibacterial toxin requires different immunity proteins depending whether it’s intra or extracellular
Distinct immunity protein families mediate compartment-specificneutralisation of a bacterial toxin https://www.biorxiv.org/content/10.1101/2025.05.31.657152v1
June 1, 2025 at 7:37 AM
Check out our latest preprint! We show that the same antibacterial toxin requires different immunity proteins depending whether it’s intra or extracellular
Reposted by David Albesa
@pbernalt6ss.bsky.social and @davidalbesa.bsky.social opening #ETOX2025. Looking forward to some hot science in the next couple of days.
June 29, 2025 at 5:11 PM
@pbernalt6ss.bsky.social and @davidalbesa.bsky.social opening #ETOX2025. Looking forward to some hot science in the next couple of days.
Reposted by David Albesa
Reposted by David Albesa
Reposted by David Albesa
Heading home after a wonderful week in Bilbao and the Basque country for #ETOX25. Thank you @davidalbesa.bsky.social and @pbernalt6ss.bsky.social for organizing this lovely meeting!
July 5, 2025 at 11:46 AM
Heading home after a wonderful week in Bilbao and the Basque country for #ETOX25. Thank you @davidalbesa.bsky.social and @pbernalt6ss.bsky.social for organizing this lovely meeting!
New research reveals the mode of action of the Pseudomonas aeruginosa #T6SS Tse4 toxin. Tse4 forms ion-selective, voltage-sensitive channels in bacterial membranes, coupling cell depolarization with K⁺ efflux. This highlights a key antibacterial strategy. #PFPsky
doi.org/10.1371/jour...
doi.org/10.1371/jour...
June 6, 2025 at 9:49 PM
New research reveals the mode of action of the Pseudomonas aeruginosa #T6SS Tse4 toxin. Tse4 forms ion-selective, voltage-sensitive channels in bacterial membranes, coupling cell depolarization with K⁺ efflux. This highlights a key antibacterial strategy. #PFPsky
doi.org/10.1371/jour...
doi.org/10.1371/jour...