Amanda Oakie
@aoakie.bsky.social
Postdoctoral fellow, Nostro Lab, McEwen Stem Cell Institute. Islet biology enthusiast.
Reposted by Amanda Oakie
🌟 New opportunity - Fourteen summer studentships are available for undergraduate and med students to carry out summer research in diabetes under the supervision of a member of the BBDC. Learn more! bbdc.org/funding/fund...
November 6, 2025 at 5:21 PM
🌟 New opportunity - Fourteen summer studentships are available for undergraduate and med students to carry out summer research in diabetes under the supervision of a member of the BBDC. Learn more! bbdc.org/funding/fund...
Congratulations, Cristina, well deserved!
Congratulations to Dr. Cristina Nostro from @uhn.ca’s McEwen Stem Cell Institute on winning the prestigious 2025 Till & McCulloch Award! 🎉
Her impactful research in #diabetes and #RegenerativeMedicine brings us closer to #AHealthierWorld every day.
🔗 Read more: www.uhnresearch.ca/news/honouri...
Her impactful research in #diabetes and #RegenerativeMedicine brings us closer to #AHealthierWorld every day.
🔗 Read more: www.uhnresearch.ca/news/honouri...
November 5, 2025 at 7:27 PM
Congratulations, Cristina, well deserved!
Reposted by Amanda Oakie
Congratulations to Dr. Cristina Nostro from @uhn.ca’s McEwen Stem Cell Institute on winning the prestigious 2025 Till & McCulloch Award! 🎉
Her impactful research in #diabetes and #RegenerativeMedicine brings us closer to #AHealthierWorld every day.
🔗 Read more: www.uhnresearch.ca/news/honouri...
Her impactful research in #diabetes and #RegenerativeMedicine brings us closer to #AHealthierWorld every day.
🔗 Read more: www.uhnresearch.ca/news/honouri...
November 5, 2025 at 4:00 PM
Congratulations to Dr. Cristina Nostro from @uhn.ca’s McEwen Stem Cell Institute on winning the prestigious 2025 Till & McCulloch Award! 🎉
Her impactful research in #diabetes and #RegenerativeMedicine brings us closer to #AHealthierWorld every day.
🔗 Read more: www.uhnresearch.ca/news/honouri...
Her impactful research in #diabetes and #RegenerativeMedicine brings us closer to #AHealthierWorld every day.
🔗 Read more: www.uhnresearch.ca/news/honouri...
Reposted by Amanda Oakie
(1/2) 🇨🇦 Canada changed the world with the discovery of insulin — and 40 years later, with #StemCells, launched #RegenerativeMedicine.
Today, another breakthrough is within reach.
Today, another breakthrough is within reach.
(1/2) A century after discovering insulin, Canadian innovation is once again poised to change the world — this time through #RegenerativeMedicine and advanced therapeutics.
In an op-ed with Jessica Diniz, President & CEO of @breakthrought1dca.bsky.social,
In an op-ed with Jessica Diniz, President & CEO of @breakthrought1dca.bsky.social,
Curing Type 1 diabetes could be Canada’s legacy
From insulin to regenerative therapy, Canada’s contribution to diabetes research is unmatched. The question is whether we’ll continue to lead or watch others cross the finish line.
www.hilltimes.com
October 30, 2025 at 7:15 PM
(1/2) 🇨🇦 Canada changed the world with the discovery of insulin — and 40 years later, with #StemCells, launched #RegenerativeMedicine.
Today, another breakthrough is within reach.
Today, another breakthrough is within reach.
Reposted by Amanda Oakie
📢 Exciting job opportunity!
The Epelman Lab at University Health Network is hiring a Postdoctoral Researcher in #Cardiology to study engineered heart tissue, tissue regeneration, and macrophage biology. 🫀
Learn more and apply! ➡️ stemcellnetwork.ca/career-oppor...
The Epelman Lab at University Health Network is hiring a Postdoctoral Researcher in #Cardiology to study engineered heart tissue, tissue regeneration, and macrophage biology. 🫀
Learn more and apply! ➡️ stemcellnetwork.ca/career-oppor...
October 27, 2025 at 12:50 PM
📢 Exciting job opportunity!
The Epelman Lab at University Health Network is hiring a Postdoctoral Researcher in #Cardiology to study engineered heart tissue, tissue regeneration, and macrophage biology. 🫀
Learn more and apply! ➡️ stemcellnetwork.ca/career-oppor...
The Epelman Lab at University Health Network is hiring a Postdoctoral Researcher in #Cardiology to study engineered heart tissue, tissue regeneration, and macrophage biology. 🫀
Learn more and apply! ➡️ stemcellnetwork.ca/career-oppor...
Reposted by Amanda Oakie
📢 McGill University is hiring!
A tenure-track Assistant Professor position is open in Pluripotent Stem Cells in Regenerative Medicine, within the Department of Pharmacology and Therapeutics, in partnership with the Meakins-Christie Labs at the RI-MUHC.
Apply. ➡️ stemcellnetwork.ca/wp-content/u...
A tenure-track Assistant Professor position is open in Pluripotent Stem Cells in Regenerative Medicine, within the Department of Pharmacology and Therapeutics, in partnership with the Meakins-Christie Labs at the RI-MUHC.
Apply. ➡️ stemcellnetwork.ca/wp-content/u...
October 14, 2025 at 1:56 PM
📢 McGill University is hiring!
A tenure-track Assistant Professor position is open in Pluripotent Stem Cells in Regenerative Medicine, within the Department of Pharmacology and Therapeutics, in partnership with the Meakins-Christie Labs at the RI-MUHC.
Apply. ➡️ stemcellnetwork.ca/wp-content/u...
A tenure-track Assistant Professor position is open in Pluripotent Stem Cells in Regenerative Medicine, within the Department of Pharmacology and Therapeutics, in partnership with the Meakins-Christie Labs at the RI-MUHC.
Apply. ➡️ stemcellnetwork.ca/wp-content/u...
Reposted by Amanda Oakie
Yesterday we celebrated our 600th human research islet isolation in support of diabetes research (and then last night isolated the islets in the pic). I’m very fortunate to work with such a dedicated team! See more at www.isletcore.ca
September 30, 2025 at 1:09 PM
Yesterday we celebrated our 600th human research islet isolation in support of diabetes research (and then last night isolated the islets in the pic). I’m very fortunate to work with such a dedicated team! See more at www.isletcore.ca
Reposted by Amanda Oakie
I have gotten a bit behind at sharing the lab’s latest work - this paper is now published - check it out! www.cell.com/cell-reports... Long story short: insulin is the major determinant of female fat storage, with a relatively minor effect on males.
September 20, 2025 at 1:39 PM
I have gotten a bit behind at sharing the lab’s latest work - this paper is now published - check it out! www.cell.com/cell-reports... Long story short: insulin is the major determinant of female fat storage, with a relatively minor effect on males.
Reposted by Amanda Oakie
Save the date for the 2026 A-BC Islet Biology meeting! Looking forward to many fantastic presentations by trainees in islet biology from all over Canada as well as great keynote lectures. Please share widely! isletmeeting.weebly.com
September 18, 2025 at 10:56 PM
Save the date for the 2026 A-BC Islet Biology meeting! Looking forward to many fantastic presentations by trainees in islet biology from all over Canada as well as great keynote lectures. Please share widely! isletmeeting.weebly.com
Reposted by Amanda Oakie
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.
www.nature.com/naturecareer...
Please repost!
www.nature.com/naturecareer...
Please repost!
August 28, 2025 at 6:34 AM
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.
www.nature.com/naturecareer...
Please repost!
www.nature.com/naturecareer...
Please repost!
Reposted by Amanda Oakie
Discover MyRoad, a platform dedicated to research training and mentorship in the fields of obesity, diabetes, and cardiometabolic diseases. New opportunities are available this fall, including cohort-based training, travel awards, and health research exchange competitions. www.myroadplatform.ca/en
August 13, 2025 at 1:32 AM
Discover MyRoad, a platform dedicated to research training and mentorship in the fields of obesity, diabetes, and cardiometabolic diseases. New opportunities are available this fall, including cohort-based training, travel awards, and health research exchange competitions. www.myroadplatform.ca/en
Reposted by Amanda Oakie
The @calvin-ke.bsky.social lab is hiring a Postdoctoral Fellow! Apply to join the team, where you will lead community-engaged, equity-focused type 2 diabetes research (qualitative & mixed-methods). jobs.smartrecruiters.com/UniversityHe...
August 6, 2025 at 8:22 PM
The @calvin-ke.bsky.social lab is hiring a Postdoctoral Fellow! Apply to join the team, where you will lead community-engaged, equity-focused type 2 diabetes research (qualitative & mixed-methods). jobs.smartrecruiters.com/UniversityHe...
Reposted by Amanda Oakie
Very proud to share the first review from the lab with contributions of all lab members. Writing this gave our new lab opportunity to read and discuss many papers and grow as a team. www.frontiersin.org/journals/imm...
www.frontiersin.org
August 4, 2025 at 1:22 PM
Very proud to share the first review from the lab with contributions of all lab members. Writing this gave our new lab opportunity to read and discuss many papers and grow as a team. www.frontiersin.org/journals/imm...
👇👇👇
Official posting coming soon, but here's a heads-up:
#Postdoc Opportunity for individuals with an interest in advancing the understanding of pancreatic islet hormones in health and #diabetes. Diverse backgrounds, skill sets and experiences are welcome!
www.bcell.org
#Postdoc Opportunity for individuals with an interest in advancing the understanding of pancreatic islet hormones in health and #diabetes. Diverse backgrounds, skill sets and experiences are welcome!
www.bcell.org
July 25, 2025 at 2:24 PM
👇👇👇
Reposted by Amanda Oakie
A regulated pathway through which glucagon modulates insulin release via alpha to beta cell communication and control of GLP-1R internalization and beta cell Ca2+ responses to high glucose @cp-cellmetabolism.bsky.social @daveyboyhod.bsky.social #islets www.cell.com/cell-metabol...
Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication
Tong et al. utilize advanced imaging approaches to reveal that beta cells located
next to alpha cells are specially adapted as glucagon sensors by virtue of their high
expression levels of GLP1R. Thes...
www.cell.com
July 15, 2025 at 9:43 PM
A regulated pathway through which glucagon modulates insulin release via alpha to beta cell communication and control of GLP-1R internalization and beta cell Ca2+ responses to high glucose @cp-cellmetabolism.bsky.social @daveyboyhod.bsky.social #islets www.cell.com/cell-metabol...
Reposted by Amanda Oakie
📣 Exciting opportunity!
The McEwen Stem Cell Institute at @uhnresearch.ca is hiring a Postdoc Researcher to join the Protze Lab. The project focuses on #HumanPluripotent stem cell-derived AVNLPCs and their application as a biological conduction bridge.
🔗 jobs.smartrecruiters.com/UniversityHe...
The McEwen Stem Cell Institute at @uhnresearch.ca is hiring a Postdoc Researcher to join the Protze Lab. The project focuses on #HumanPluripotent stem cell-derived AVNLPCs and their application as a biological conduction bridge.
🔗 jobs.smartrecruiters.com/UniversityHe...
July 11, 2025 at 6:13 PM
📣 Exciting opportunity!
The McEwen Stem Cell Institute at @uhnresearch.ca is hiring a Postdoc Researcher to join the Protze Lab. The project focuses on #HumanPluripotent stem cell-derived AVNLPCs and their application as a biological conduction bridge.
🔗 jobs.smartrecruiters.com/UniversityHe...
The McEwen Stem Cell Institute at @uhnresearch.ca is hiring a Postdoc Researcher to join the Protze Lab. The project focuses on #HumanPluripotent stem cell-derived AVNLPCs and their application as a biological conduction bridge.
🔗 jobs.smartrecruiters.com/UniversityHe...
Reposted by Amanda Oakie
We are launching a new initiative to support experimental design, data management/analysis and bioinformatics. Early days yet, but check it out here.
www.bcell.org/adi-datasci....
www.bcell.org/adi-datasci....
July 8, 2025 at 10:01 PM
We are launching a new initiative to support experimental design, data management/analysis and bioinformatics. Early days yet, but check it out here.
www.bcell.org/adi-datasci....
www.bcell.org/adi-datasci....
Reposted by Amanda Oakie
Come join us in Vancouver! Exciting opportunity for a more senior investigator researching new regenerative medicine approaches for Type 1 diabetes. $8M in funding for successful candidate research.ubc.ca/media/file/j...
research.ubc.ca
July 7, 2025 at 8:07 PM
Come join us in Vancouver! Exciting opportunity for a more senior investigator researching new regenerative medicine approaches for Type 1 diabetes. $8M in funding for successful candidate research.ubc.ca/media/file/j...
Reposted by Amanda Oakie
Very excited about our project aiming at advancing cell therapies for type 1 diabetes. and very thankful for receiving funding from @stemcellnetwork.ca
🚨 BIG NEWS! SCN announces $33M to advance 36 #RegenerativeMedicine research projects and #ClinicalTrials!
Learn more. ➡️ stemcellnetwork.ca/research/res...
Learn more. ➡️ stemcellnetwork.ca/research/res...
The Stem Cell Network Announces $33M to Advance Regenerative Medicine Research and Clinical Trials
YouTube video by Stem Cell Network - Réseau de cellules souches
youtu.be
June 27, 2025 at 11:13 AM
Very excited about our project aiming at advancing cell therapies for type 1 diabetes. and very thankful for receiving funding from @stemcellnetwork.ca
Reposted by Amanda Oakie
Review on metabolism in stem cell derived beta cells from former PhD student with us, Frank Lin. Cell Reports @cp-cellreports.bsky.social
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Glucose metabolism and regulation in establishing human stem cell-derived β cell maturation
Efforts to generate mature stem cell-derived β (SC-β) cells have been ongoing for decades, yet their functional performance still falls short of prima…
www.sciencedirect.com
June 25, 2025 at 9:49 AM
Review on metabolism in stem cell derived beta cells from former PhD student with us, Frank Lin. Cell Reports @cp-cellreports.bsky.social
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Amanda Oakie
There is still a spot for a PhD student or Postdoc in the Lim Lab! If you are interested in metabolism, 14-3-3 proteins, adipocytes, or beta-cells, please email me (details at www.limlab.ca). International applicants are welcome!
Positions are fully funded. Looking forward to working with you!
Positions are fully funded. Looking forward to working with you!
Lim Lab
Exploring how 14-3-3 proteins contribute to metabolism and metabolic diseases
www.limlab.ca
May 28, 2025 at 12:21 AM
There is still a spot for a PhD student or Postdoc in the Lim Lab! If you are interested in metabolism, 14-3-3 proteins, adipocytes, or beta-cells, please email me (details at www.limlab.ca). International applicants are welcome!
Positions are fully funded. Looking forward to working with you!
Positions are fully funded. Looking forward to working with you!
Congrats to @sarahcolpitts.bsky.social and the @sarahcrome.bsky.social lab! Check out the effects of ILC-islet co-tx below 👇👇
🧬 Excited to share our latest study now In Press: In this study led by rising star @sarahcolpitts.bsky.social, we show that IL-10⁺ #ILC2s prevent rejection and improve islet graft survival and function in humanized mouse models. Read more: doi.org/10.1016/j.aj... #Immunology #ImmunoSky #CellTherapy
Redirecting
doi.org
May 26, 2025 at 3:52 PM
Congrats to @sarahcolpitts.bsky.social and the @sarahcrome.bsky.social lab! Check out the effects of ILC-islet co-tx below 👇👇
Neat discussion below! 👇👇
📣 NEW PAPER ALERT! 🧵
I love kidney organoids - tiny nephron clusters grown in the lab from pluripotent stem cells. But can they treat kidney disease? New data suggests they can (in mice)!
Let's dive in ⬇️
tinyurl.com/mr3sd6vu
#KidneyOrganoids #CellTherapy #ChronicKidneyDisease #AcuteKidneyInjury
I love kidney organoids - tiny nephron clusters grown in the lab from pluripotent stem cells. But can they treat kidney disease? New data suggests they can (in mice)!
Let's dive in ⬇️
tinyurl.com/mr3sd6vu
#KidneyOrganoids #CellTherapy #ChronicKidneyDisease #AcuteKidneyInjury
Human iPSC–derived nephron progenitor cells treat acute kidney injury and chronic kidney disease in mouse models
Expanded human iPSC–derived nephron progenitor cells secrete renoprotective factors that have therapeutic potential for AKI and CKD.
tinyurl.com
May 20, 2025 at 3:01 PM
Neat discussion below! 👇👇
Reposted by Amanda Oakie
📣 NEW PAPER ALERT! 🧵
I love kidney organoids - tiny nephron clusters grown in the lab from pluripotent stem cells. But can they treat kidney disease? New data suggests they can (in mice)!
Let's dive in ⬇️
tinyurl.com/mr3sd6vu
#KidneyOrganoids #CellTherapy #ChronicKidneyDisease #AcuteKidneyInjury
I love kidney organoids - tiny nephron clusters grown in the lab from pluripotent stem cells. But can they treat kidney disease? New data suggests they can (in mice)!
Let's dive in ⬇️
tinyurl.com/mr3sd6vu
#KidneyOrganoids #CellTherapy #ChronicKidneyDisease #AcuteKidneyInjury
Human iPSC–derived nephron progenitor cells treat acute kidney injury and chronic kidney disease in mouse models
Expanded human iPSC–derived nephron progenitor cells secrete renoprotective factors that have therapeutic potential for AKI and CKD.
tinyurl.com
May 20, 2025 at 12:48 PM
📣 NEW PAPER ALERT! 🧵
I love kidney organoids - tiny nephron clusters grown in the lab from pluripotent stem cells. But can they treat kidney disease? New data suggests they can (in mice)!
Let's dive in ⬇️
tinyurl.com/mr3sd6vu
#KidneyOrganoids #CellTherapy #ChronicKidneyDisease #AcuteKidneyInjury
I love kidney organoids - tiny nephron clusters grown in the lab from pluripotent stem cells. But can they treat kidney disease? New data suggests they can (in mice)!
Let's dive in ⬇️
tinyurl.com/mr3sd6vu
#KidneyOrganoids #CellTherapy #ChronicKidneyDisease #AcuteKidneyInjury
Reposted by Amanda Oakie
Excited to enroll our first participant for testing an agent (tolimidone) we hope will promote beta cell regeneration, building on preclinical work from Dr Jean Buteau at @albertadiabetes.bsky.social. Supported by Alberta Diabetes Foundation & biodexa pharmaceuticals www.ualberta.ca/en/folio/202...
Could a pill cure diabetes? A U of A researcher is working on it
A simple pill to treat or even cure diabetes could be possible, thanks to University of Alberta research — and funding that is laying vital groundwork.
www.ualberta.ca
May 15, 2025 at 5:42 PM
Excited to enroll our first participant for testing an agent (tolimidone) we hope will promote beta cell regeneration, building on preclinical work from Dr Jean Buteau at @albertadiabetes.bsky.social. Supported by Alberta Diabetes Foundation & biodexa pharmaceuticals www.ualberta.ca/en/folio/202...