Anchel de Jaime-Soguero
@ancheldjs.bsky.social
Cell and developmental biology enthusiast studying cellular communication. Group leader at IRIBHM-ULB, Belgium
Pinned
PhD Position — IRIBHM Jacques E. Dumont
Anchel De Jaime Soguero Lab: PhD position in cellular and developmental biology
www.iribhm.org
🚨 PhD opportunity
Interested in stem cells, mammalian development, and omics?
The Migeotte & De Jaime-Soguero labs are recruiting a PhD student with bioinformatics background to work on embryonic and extraembryonic development.
🗓 Deadline April 2026
👇 Details below
www.iribhm.org/open-positio...
Interested in stem cells, mammalian development, and omics?
The Migeotte & De Jaime-Soguero labs are recruiting a PhD student with bioinformatics background to work on embryonic and extraembryonic development.
🗓 Deadline April 2026
👇 Details below
www.iribhm.org/open-positio...
🚨 PhD opportunity
Interested in stem cells, mammalian development, and omics?
The Migeotte & De Jaime-Soguero labs are recruiting a PhD student with bioinformatics background to work on embryonic and extraembryonic development.
🗓 Deadline April 2026
👇 Details below
www.iribhm.org/open-positio...
Interested in stem cells, mammalian development, and omics?
The Migeotte & De Jaime-Soguero labs are recruiting a PhD student with bioinformatics background to work on embryonic and extraembryonic development.
🗓 Deadline April 2026
👇 Details below
www.iribhm.org/open-positio...
PhD Position — IRIBHM Jacques E. Dumont
Anchel De Jaime Soguero Lab: PhD position in cellular and developmental biology
www.iribhm.org
January 29, 2026 at 9:49 AM
🚨 PhD opportunity
Interested in stem cells, mammalian development, and omics?
The Migeotte & De Jaime-Soguero labs are recruiting a PhD student with bioinformatics background to work on embryonic and extraembryonic development.
🗓 Deadline April 2026
👇 Details below
www.iribhm.org/open-positio...
Interested in stem cells, mammalian development, and omics?
The Migeotte & De Jaime-Soguero labs are recruiting a PhD student with bioinformatics background to work on embryonic and extraembryonic development.
🗓 Deadline April 2026
👇 Details below
www.iribhm.org/open-positio...
Reposted by Anchel de Jaime-Soguero
🚨 Paper alert! The final version of our latest manuscript is published. We are excited to share this new resource for the zebrafish community and beyond: doi.org/10.7554/eLif... Congratulations to all authors! 🥳
A single-cell transcriptomic atlas reveals resident dendritic-like cells in the zebrafish brain parenchyma
The zebrafish brain combines a conserved heterogeneity of immune cells with a unique dendritic cell-like population.
doi.org
December 13, 2025 at 5:14 PM
🚨 Paper alert! The final version of our latest manuscript is published. We are excited to share this new resource for the zebrafish community and beyond: doi.org/10.7554/eLif... Congratulations to all authors! 🥳
Reposted by Anchel de Jaime-Soguero
Beautiful, thorough, personal in places, memoir of John Gurdon from Eddy de Robertis, disciple and friend. Å #MustRead about a generation and a time from which we have moved on but that laid the foundation for contemporary biology.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
December 23, 2025 at 5:59 AM
Beautiful, thorough, personal in places, memoir of John Gurdon from Eddy de Robertis, disciple and friend. Å #MustRead about a generation and a time from which we have moved on but that laid the foundation for contemporary biology.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Cellular signaling (BMP/SMAD) at the helm of chromosomal instability in cancer, similar as what we described during development and lineage specification. Congrats to our collaborators at the Bastians lab.
SMAD4 loss drives cancer chromosomal instability through transcription-replication conflict-induced replication stress https://www.biorxiv.org/content/10.64898/2025.12.17.694873v1
December 20, 2025 at 8:43 PM
Cellular signaling (BMP/SMAD) at the helm of chromosomal instability in cancer, similar as what we described during development and lineage specification. Congrats to our collaborators at the Bastians lab.
‼️‼️📢📢 Job Alert!
Our lab at @iribhm.bsky.social - @ulbruxelles.bsky.social is seeking for a PhD student to work on the proteostasis of early mammalian development using stem cell models and the embryo. If you are enthusiastic about cell and dev biology, please apply!
Our lab at @iribhm.bsky.social - @ulbruxelles.bsky.social is seeking for a PhD student to work on the proteostasis of early mammalian development using stem cell models and the embryo. If you are enthusiastic about cell and dev biology, please apply!
July 16, 2025 at 8:48 AM
‼️‼️📢📢 Job Alert!
Our lab at @iribhm.bsky.social - @ulbruxelles.bsky.social is seeking for a PhD student to work on the proteostasis of early mammalian development using stem cell models and the embryo. If you are enthusiastic about cell and dev biology, please apply!
Our lab at @iribhm.bsky.social - @ulbruxelles.bsky.social is seeking for a PhD student to work on the proteostasis of early mammalian development using stem cell models and the embryo. If you are enthusiastic about cell and dev biology, please apply!
Excited to present our work tomorrow online at Social DNAing series.
18.00PM CEST time following the link below.
18.00PM CEST time following the link below.
Are you ready for the 2nd half of 2025? Social DNAing is ready. Check out the speaker list and schedule! Sign up at www.cancer.columbia.edu/research/pro...
July 2, 2025 at 10:24 AM
Excited to present our work tomorrow online at Social DNAing series.
18.00PM CEST time following the link below.
18.00PM CEST time following the link below.
Reposted by Anchel de Jaime-Soguero
The modularity of the mammalian #embryo in display. Controlled assembly of classic #gastruloids and uncommitted precursors in #hypoxia, patterns the AP axis
www.biorxiv.org/content/10.1...
Beautiful & insightful from @bulutkarslioglu.bsky.social group. Building models to learn and learning.
www.biorxiv.org/content/10.1...
Beautiful & insightful from @bulutkarslioglu.bsky.social group. Building models to learn and learning.
June 23, 2025 at 3:06 PM
The modularity of the mammalian #embryo in display. Controlled assembly of classic #gastruloids and uncommitted precursors in #hypoxia, patterns the AP axis
www.biorxiv.org/content/10.1...
Beautiful & insightful from @bulutkarslioglu.bsky.social group. Building models to learn and learning.
www.biorxiv.org/content/10.1...
Beautiful & insightful from @bulutkarslioglu.bsky.social group. Building models to learn and learning.
Reposted by Anchel de Jaime-Soguero
Crick researchers have developed a new stem cell model of the mature amniotic sac development.
The team is now exploring the potential for using these new 3D models in clinical applications, such as cornea reconstruction and treating ulcers.
www.crick.ac.uk/news/2025-05...
The team is now exploring the potential for using these new 3D models in clinical applications, such as cornea reconstruction and treating ulcers.
www.crick.ac.uk/news/2025-05...
New stem cell model sheds light on human amniotic sac development
Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four wee...
www.crick.ac.uk
May 15, 2025 at 4:11 PM
Crick researchers have developed a new stem cell model of the mature amniotic sac development.
The team is now exploring the potential for using these new 3D models in clinical applications, such as cornea reconstruction and treating ulcers.
www.crick.ac.uk/news/2025-05...
The team is now exploring the potential for using these new 3D models in clinical applications, such as cornea reconstruction and treating ulcers.
www.crick.ac.uk/news/2025-05...
Reposted by Anchel de Jaime-Soguero
Join us tomorrow for our next seminar:
🗓️ Thursday, May 08
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET
🗓️ Thursday, May 08
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET
Next Western 🌙 VGZT coming up:
🗓️ Thursday, May 08
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET
👉 @ancheldjs.bsky.social (Regulation of chromosome segregation fidelity across lineage specification)
👉 @emmanuelhaillot.bsky.social (Mesoderm and endoderm formation in Nematostella)
🗓️ Thursday, May 08
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET
👉 @ancheldjs.bsky.social (Regulation of chromosome segregation fidelity across lineage specification)
👉 @emmanuelhaillot.bsky.social (Mesoderm and endoderm formation in Nematostella)
May 7, 2025 at 2:25 PM
Join us tomorrow for our next seminar:
🗓️ Thursday, May 08
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET
🗓️ Thursday, May 08
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET
Looking forward to giving this talk next week!
Next Western 🌙 VGZT coming up:
🗓️ Thursday, May 08
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET
👉 @ancheldjs.bsky.social (Regulation of chromosome segregation fidelity across lineage specification)
👉 @emmanuelhaillot.bsky.social (Mesoderm and endoderm formation in Nematostella)
🗓️ Thursday, May 08
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET
👉 @ancheldjs.bsky.social (Regulation of chromosome segregation fidelity across lineage specification)
👉 @emmanuelhaillot.bsky.social (Mesoderm and endoderm formation in Nematostella)
May 2, 2025 at 3:27 PM
Looking forward to giving this talk next week!
Reposted by Anchel de Jaime-Soguero
Aneuploidy is the leading cause of pregnancy loss. In work led by @saracarioscia.bsky.social and @aabiddanda.bsky.social, we reanalyzed genetic testing data from 139,416 IVF embryos to discover variants associated with recombination phenotypes and aneuploidy risk. www.medrxiv.org/content/10.1...
April 7, 2025 at 2:01 PM
Aneuploidy is the leading cause of pregnancy loss. In work led by @saracarioscia.bsky.social and @aabiddanda.bsky.social, we reanalyzed genetic testing data from 139,416 IVF embryos to discover variants associated with recombination phenotypes and aneuploidy risk. www.medrxiv.org/content/10.1...
Last few months have been of change. I finished my postdoc at @cosheidelberg.bsky.social and moved to Belgium to begin my research group at @iribhm.bsky.social. I will reflect here my thoughts about the last years experience.
March 30, 2025 at 2:41 PM
Last few months have been of change. I finished my postdoc at @cosheidelberg.bsky.social and moved to Belgium to begin my research group at @iribhm.bsky.social. I will reflect here my thoughts about the last years experience.
Reposted by Anchel de Jaime-Soguero
In this Review, @eliananehme.bsky.social, @amiteshp.bsky.social, Isabelle Migeotte and @pasquelab.bsky.social give an overview of the embryonic origin and function of extra-embryonic mesoderm in vertebrates from in vivo studies.
journals.biologists.com/dev/article/...
journals.biologists.com/dev/article/...
March 17, 2025 at 4:29 PM
In this Review, @eliananehme.bsky.social, @amiteshp.bsky.social, Isabelle Migeotte and @pasquelab.bsky.social give an overview of the embryonic origin and function of extra-embryonic mesoderm in vertebrates from in vivo studies.
journals.biologists.com/dev/article/...
journals.biologists.com/dev/article/...
Reposted by Anchel de Jaime-Soguero
Do you want to illuminate your studies on innate immune responses? Our new biosensor monitors mtDNA from apoptosis, viral infections, other sources of dsDNA and environmental cGAMP. We also show that micro nuclei are poor activators of the #STING response
SIRF: Sergio Acebron @acebronsp.bsky.social @cosheidelberg.bsky.social and colleagues develop a new #biosensor reporting on functional interactions between dsDNA sensor STING and #IRF3, allowing to capture STING activation upon various triggers
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
February 26, 2025 at 7:44 AM
Do you want to illuminate your studies on innate immune responses? Our new biosensor monitors mtDNA from apoptosis, viral infections, other sources of dsDNA and environmental cGAMP. We also show that micro nuclei are poor activators of the #STING response
Reposted by Anchel de Jaime-Soguero
SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).
www.embl.org/about/info/c...
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).
www.embl.org/about/info/c...
DNA replication and genome maintenance: from basic biology to disease
www.embl.org
February 26, 2025 at 3:22 PM
SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).
www.embl.org/about/info/c...
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).
www.embl.org/about/info/c...
Design of a STING fluorescent real time biosensor. Tour de force of my colleague #Steve under Sergio @acebronsp.bsky.social supervision. 👏👏👏
SIRF: Sergio Acebron @acebronsp.bsky.social @cosheidelberg.bsky.social and colleagues develop a new #biosensor reporting on functional interactions between dsDNA sensor STING and #IRF3, allowing to capture STING activation upon various triggers
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
February 22, 2025 at 2:44 PM
Design of a STING fluorescent real time biosensor. Tour de force of my colleague #Steve under Sergio @acebronsp.bsky.social supervision. 👏👏👏
Novel insights on cellular signaling regulation of DNA replicative dynamics.
BMP signaling not only prevents from replicative stress in pluripotency, as we described recently (www.nature.com/articles/s41...) but also drives regeneration through same mechanisms.
www.nature.com/articles/s41...
BMP signaling not only prevents from replicative stress in pluripotency, as we described recently (www.nature.com/articles/s41...) but also drives regeneration through same mechanisms.
www.nature.com/articles/s41...
BMP signaling promotes zebrafish heart regeneration via alleviation of replication stress - Nature Communications
Zebrafish show robust heart regeneration after injury. Here they show that zebrafish cardiomyocytes experience replication stress, which BMP signaling alleviates via a conserved mechanism of replicati...
www.nature.com
February 19, 2025 at 3:49 PM
Novel insights on cellular signaling regulation of DNA replicative dynamics.
BMP signaling not only prevents from replicative stress in pluripotency, as we described recently (www.nature.com/articles/s41...) but also drives regeneration through same mechanisms.
www.nature.com/articles/s41...
BMP signaling not only prevents from replicative stress in pluripotency, as we described recently (www.nature.com/articles/s41...) but also drives regeneration through same mechanisms.
www.nature.com/articles/s41...
Reposted by Anchel de Jaime-Soguero
Surprisingly we find that as few as 2 starting p53KO cells will compete in an environment of @300 WT cells. Also, see an input for BMP & Wnt signalling that mirrors work on the control of chromosomal segregation in stem cells www.nature.com/articles/s41...
January 26, 2025 at 4:36 PM
Surprisingly we find that as few as 2 starting p53KO cells will compete in an environment of @300 WT cells. Also, see an input for BMP & Wnt signalling that mirrors work on the control of chromosomal segregation in stem cells www.nature.com/articles/s41...
Great work on cell competition during mammalian gastrulation. It aligns with our observations on chromosome stability-driven by morphogens and open further questions on the relation of cellular fitness and genome integrity. Congrats!
1/3 Embryogenesis requires fit cells. Here, following work from @miguel-torres-1963.bsky.social & @tristanrodriguez72.bsky.social and led by @joshifrenster.bsky.social we develop a #gastruloid model of #CellCompetition
www.biorxiv.org/content/10.1...
showing it recapitulates much of the embryo 🧵
www.biorxiv.org/content/10.1...
showing it recapitulates much of the embryo 🧵
January 27, 2025 at 7:51 AM
Great work on cell competition during mammalian gastrulation. It aligns with our observations on chromosome stability-driven by morphogens and open further questions on the relation of cellular fitness and genome integrity. Congrats!
Great city, great environment and cool projects (including stem cell modelling, development, homeostasis and cancer biology).
Have a look to the research groups offer and do not hesitate to apply!
Have a look to the research groups offer and do not hesitate to apply!
🎉 We’re pleased to announce the launch of the IRIBHM Jacques E. Dumont International PhD Programme 2025! A great opportunity to shape the future of biomedical sciences by preparing the next generation of leaders. 🚀 Don’t miss your chance to be part of this innovative adventure! iribhmphd.ulb.be
January 20, 2025 at 4:17 PM
Great city, great environment and cool projects (including stem cell modelling, development, homeostasis and cancer biology).
Have a look to the research groups offer and do not hesitate to apply!
Have a look to the research groups offer and do not hesitate to apply!
Reposted by Anchel de Jaime-Soguero
Great opportunity for a PhD in Brussels. Outstanding mentor and project addressing bottlenecks in human development
🚨 🚨 Job Alert!
I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!
I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!
January 12, 2025 at 9:10 AM
Great opportunity for a PhD in Brussels. Outstanding mentor and project addressing bottlenecks in human development
⚠️📢 Few weeks to close the call. If you love cell & devbio, and are interested on doing a PhD in stress resilisence, please APPLY!
🚨 🚨 Job Alert!
I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!
I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!
January 5, 2025 at 8:15 AM
⚠️📢 Few weeks to close the call. If you love cell & devbio, and are interested on doing a PhD in stress resilisence, please APPLY!
Gracias a Pilar Perla y @heraldo.es por la difusión de nuestro trabajo en el lab de Sergio Acebrón @acebronsp.bsky.social y mi opinión sobre la investigación básica en mi tierra, Aragón.
www.heraldo.es/noticias/ara...
www.heraldo.es/noticias/ara...
Anchel de Jaime Soguero: "Aragón necesita dar un impulso a la investigación básica"
Tras pasar por Alemania, el biomédico aragonés lidera su propio grupo en el Instituto Interdisciplinar de Biología Humana y Molecular, en Bruselas.
www.heraldo.es
December 20, 2024 at 2:13 PM
Gracias a Pilar Perla y @heraldo.es por la difusión de nuestro trabajo en el lab de Sergio Acebrón @acebronsp.bsky.social y mi opinión sobre la investigación básica en mi tierra, Aragón.
www.heraldo.es/noticias/ara...
www.heraldo.es/noticias/ara...
Reposted by Anchel de Jaime-Soguero
Registration is open for the 12th Advances in Stem Cell Biology Course #ASCBcourse at the @pasteur.fr
Hands-on training in different models, embryonic stem cells, iPS cells and much more on #StemCells.
🕘June23-July04, 2025
👉https://qrfy.io/VEcoKQpGfV
Hands-on training in different models, embryonic stem cells, iPS cells and much more on #StemCells.
🕘June23-July04, 2025
👉https://qrfy.io/VEcoKQpGfV
December 17, 2024 at 9:52 AM
Registration is open for the 12th Advances in Stem Cell Biology Course #ASCBcourse at the @pasteur.fr
Hands-on training in different models, embryonic stem cells, iPS cells and much more on #StemCells.
🕘June23-July04, 2025
👉https://qrfy.io/VEcoKQpGfV
Hands-on training in different models, embryonic stem cells, iPS cells and much more on #StemCells.
🕘June23-July04, 2025
👉https://qrfy.io/VEcoKQpGfV
Reposted by Anchel de Jaime-Soguero
🚨 🚨 Job Alert!
I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!
I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!
November 26, 2024 at 11:43 AM
🚨 🚨 Job Alert!
I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!
I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!