Zha Lab
@zhalab.bsky.social
#scientist #mom interested in #DNA repair #mouse genetics #hematopoiesis #immunodeficiency #lymphoma, and #leukemia. opinions are my own.
Due to unforeseen reason, Tomorrow’s Social DNAing ( Oct.9 ) will be cancelled and we will see each other next week on Oct 16th. Thank you for your understanding.
October 8, 2025 at 2:49 PM
Due to unforeseen reason, Tomorrow’s Social DNAing ( Oct.9 ) will be cancelled and we will see each other next week on Oct 16th. Thank you for your understanding.
Reposted by Zha Lab
Co-organizing a one day FREE conference on Genome Instability- Discovery to Personalized Medicine 11/1/25. Please join us! Short talks available. https//noncredit.t...
September 3, 2025 at 3:36 PM
Co-organizing a one day FREE conference on Genome Instability- Discovery to Personalized Medicine 11/1/25. Please join us! Short talks available. https//noncredit.t...
Reposted by Zha Lab
I spoke with Jade Hindmon, host of @kpbssandiego.bsky.social Midday Edition, about the consequences of the current administration’s cuts to science funding. Please share to help spread the word and raise awareness.
www.kpbs.org/podcasts/kpb...
www.kpbs.org/podcasts/kpb...
Nobel laureate on how Trump's cuts are hurting science
Neuroscientist, biologist and 2021 Nobel Prize winner Ardem Patapoutian joined Midday Edition to talk about how the Trump administration's effort to cut back on science spending is impacting researche...
www.kpbs.org
June 19, 2025 at 12:27 AM
I spoke with Jade Hindmon, host of @kpbssandiego.bsky.social Midday Edition, about the consequences of the current administration’s cuts to science funding. Please share to help spread the word and raise awareness.
www.kpbs.org/podcasts/kpb...
www.kpbs.org/podcasts/kpb...
Please join us celebrate the 5th year birthday of Social DNAing! Dr. Chapman will take the stage in the coming week. Sign up at cancer.columbia.edu/research/progr…
June 15, 2025 at 1:57 AM
Please join us celebrate the 5th year birthday of Social DNAing! Dr. Chapman will take the stage in the coming week. Sign up at cancer.columbia.edu/research/progr…
Here is a super productive PAR lab.
A postdoc position is available in our lab to study ADP-ribosylation and ubiquitylation signalling! We are looking for someone with experience in structural biology and biochemistry. The application deadline is June 20th.
my.corehr.com/pls/uoxrecru...
my.corehr.com/pls/uoxrecru...
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my.corehr.com
June 6, 2025 at 2:48 PM
Here is a super productive PAR lab.
Are you ready for the 2nd half of 2025? Social DNAing is ready. Check out the speaker list and schedule! Sign up at www.cancer.columbia.edu/research/pro...
May 20, 2025 at 2:58 AM
Are you ready for the 2nd half of 2025? Social DNAing is ready. Check out the speaker list and schedule! Sign up at www.cancer.columbia.edu/research/pro...
Excited to share our new paper on Nature - how Ku accommodates Alu expansion in primates by binding to dsRNA, providing a clue for both the high levels of Ku and its essentiality in human cells. Thank @chaolinzhang @hchung03 @LenaSteckelberg More to come www.nature.com/articles/s41...
Ku limits RNA-induced innate immunity to allow Alu-expansion in primates - Nature
Nature - Ku limits RNA-induced innate immunity to allow Alu-expansion in primates
www.nature.com
May 16, 2025 at 11:11 PM
Excited to share our new paper on Nature - how Ku accommodates Alu expansion in primates by binding to dsRNA, providing a clue for both the high levels of Ku and its essentiality in human cells. Thank @chaolinzhang @hchung03 @LenaSteckelberg More to come www.nature.com/articles/s41...
Exciting results! Using AID-Degron system, Dr. Yimeng Zhu in the lab found that Ku suppresses RNA-mediated innate immunity to accommodate Alu-expansion in primates - solving the misery of Ku essentiality in human cell and uncover 94r^2 for co evolution www.biorxiv.org/content/10.1...
Ku suppresses RNA-mediated innate immune responses in human cells to accommodate primate-specific Alu expansion
Ku70 and Ku80 form Ku, a ring-shaped protein that initiates the non-homologous end-joining (NHEJ) DNA repair pathway.[1][1] Specifically, Ku binds to double-stranded DNA (dsDNA) ends and recruits othe...
www.biorxiv.org
February 10, 2025 at 4:13 PM
Exciting results! Using AID-Degron system, Dr. Yimeng Zhu in the lab found that Ku suppresses RNA-mediated innate immunity to accommodate Alu-expansion in primates - solving the misery of Ku essentiality in human cell and uncover 94r^2 for co evolution www.biorxiv.org/content/10.1...