Amélie Joly
@ameliejoly.bsky.social
Postdoctoral researcher at the @Crick.ac.uk in the lab of @irenemiguel-aliaga.bsky.social| Intestinal physiology, sex differences & metabolism in 🐁| #ForWomenInScience2024 France Young Talent
Reposted by Amélie Joly
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
Induction of menstruation in mice reveals the regulation of menstrual shedding
During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...
www.biorxiv.org
October 10, 2025 at 12:50 PM
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
Reposted by Amélie Joly
Delighted to have given our annual prizes to these two rising stars in Neuroendocrinology 👏🏻
Congratulations to Amélie Joly and Geoffrey Canet, winners of this year’s SNE Annual Prize! 🏆👏
#SNE2025
#SNE2025
October 10, 2025 at 12:10 PM
Delighted to have given our annual prizes to these two rising stars in Neuroendocrinology 👏🏻
What an honour to receive the 2025 Thesis prize of @sneuroendo.bsky.social 🤩
Huge thanks to the scientific committee, to the Fondation Obélisque and to my incredible PhD supervisors @francoisleulier.bsky.social and @filipedevadder.bsky.social 🙏
Huge thanks to the scientific committee, to the Fondation Obélisque and to my incredible PhD supervisors @francoisleulier.bsky.social and @filipedevadder.bsky.social 🙏
#ProudPI 🎓
Thrilled to share that @ameliejoly.bsky.social received the thesis prize of the @sneuroendo.bsky.social, huge congratulations! 👏
And @lucasrebiffe.bsky.social is presenting the follow-up of the project in a great poster. Exciting to see the team’s work shining! 💪
#SNE25
Thrilled to share that @ameliejoly.bsky.social received the thesis prize of the @sneuroendo.bsky.social, huge congratulations! 👏
And @lucasrebiffe.bsky.social is presenting the follow-up of the project in a great poster. Exciting to see the team’s work shining! 💪
#SNE25
October 10, 2025 at 12:07 PM
What an honour to receive the 2025 Thesis prize of @sneuroendo.bsky.social 🤩
Huge thanks to the scientific committee, to the Fondation Obélisque and to my incredible PhD supervisors @francoisleulier.bsky.social and @filipedevadder.bsky.social 🙏
Huge thanks to the scientific committee, to the Fondation Obélisque and to my incredible PhD supervisors @francoisleulier.bsky.social and @filipedevadder.bsky.social 🙏
Reposted by Amélie Joly
Congratulations to first authors @ameliejoly.bsky.social and @lucasrebiffe.bsky.social for taking this project forward.
A big thanks to @frm-officiel.bsky.social and @agencerecherche.bsky.social for funding this work, and @igflyon.bsky.social for making the right environment for the research.
A big thanks to @frm-officiel.bsky.social and @agencerecherche.bsky.social for funding this work, and @igflyon.bsky.social for making the right environment for the research.
October 9, 2025 at 4:09 PM
Congratulations to first authors @ameliejoly.bsky.social and @lucasrebiffe.bsky.social for taking this project forward.
A big thanks to @frm-officiel.bsky.social and @agencerecherche.bsky.social for funding this work, and @igflyon.bsky.social for making the right environment for the research.
A big thanks to @frm-officiel.bsky.social and @agencerecherche.bsky.social for funding this work, and @igflyon.bsky.social for making the right environment for the research.
Reposted by Amélie Joly
In normally growing juveniles, semaglutide improves glucose control without affecting growth.
But in stunted mice, it further impairs linear growth, revealing a key interplay between energy metabolism and the somatotropic axis during development.
Mechanistic, not clinical!
But in stunted mice, it further impairs linear growth, revealing a key interplay between energy metabolism and the somatotropic axis during development.
Mechanistic, not clinical!
October 9, 2025 at 4:09 PM
In normally growing juveniles, semaglutide improves glucose control without affecting growth.
But in stunted mice, it further impairs linear growth, revealing a key interplay between energy metabolism and the somatotropic axis during development.
Mechanistic, not clinical!
But in stunted mice, it further impairs linear growth, revealing a key interplay between energy metabolism and the somatotropic axis during development.
Mechanistic, not clinical!
Delighted to share that our work has just been accepted in the Journal of the Endocrine Society 🤩
Ever wondered if semaglutide can interfere with growth? Check it out!
👇👇
Ever wondered if semaglutide can interfere with growth? Check it out!
👇👇
Our new study, just accepted in the Journal of the Endocrine Society
👉 doi.org/10.1210/jend...
We found that semaglutide, beyond its metabolic effects, can exacerbate growth stunting in juvenile mice by reducing energy metabolism, a context-dependent effect of GLP-1 signaling.
👉 doi.org/10.1210/jend...
We found that semaglutide, beyond its metabolic effects, can exacerbate growth stunting in juvenile mice by reducing energy metabolism, a context-dependent effect of GLP-1 signaling.
pendingpublications
Pending Publication
doi.org
October 9, 2025 at 4:16 PM
Delighted to share that our work has just been accepted in the Journal of the Endocrine Society 🤩
Ever wondered if semaglutide can interfere with growth? Check it out!
👇👇
Ever wondered if semaglutide can interfere with growth? Check it out!
👇👇
Reposted by Amélie Joly
Impressive talks from our ECRs for a symposium that they organized at our annual conference #SNE2025 🤩😍.
Many thanks @jne-editor.bsky.social!
Many thanks @jne-editor.bsky.social!
October 9, 2025 at 4:09 PM
Impressive talks from our ECRs for a symposium that they organized at our annual conference #SNE2025 🤩😍.
Many thanks @jne-editor.bsky.social!
Many thanks @jne-editor.bsky.social!
Reposted by Amélie Joly
👩🔬J'ai commencé un kit de démarrage "chercheuses en France" go.bsky.app/TBEzKC #FemmesEnScience
J'ai besoin de votre aide pour le remplir et donner de la visibilité aux chercheuses que vous connaissez et qui sont sur Bluesky !
▶️Taguez celles que vous connaissez, je les ajoute !
J'ai besoin de votre aide pour le remplir et donner de la visibilité aux chercheuses que vous connaissez et qui sont sur Bluesky !
▶️Taguez celles que vous connaissez, je les ajoute !
September 23, 2025 at 2:22 PM
👩🔬J'ai commencé un kit de démarrage "chercheuses en France" go.bsky.app/TBEzKC #FemmesEnScience
J'ai besoin de votre aide pour le remplir et donner de la visibilité aux chercheuses que vous connaissez et qui sont sur Bluesky !
▶️Taguez celles que vous connaissez, je les ajoute !
J'ai besoin de votre aide pour le remplir et donner de la visibilité aux chercheuses que vous connaissez et qui sont sur Bluesky !
▶️Taguez celles que vous connaissez, je les ajoute !
📢 We are looking for a sandwich student to join the lab of @irenemiguel-aliaga.bsky.social at the @crick.ac.uk for a 12-month placement starting July 2025!
Interested in how the 🐁 gut changes during pregnancy? Check the project and eligibility criteria here: www.crick.ac.uk/careers-stud...
Interested in how the 🐁 gut changes during pregnancy? Check the project and eligibility criteria here: www.crick.ac.uk/careers-stud...
The sex and reproductive plasticity of the intestine
www.crick.ac.uk
September 11, 2025 at 1:38 PM
📢 We are looking for a sandwich student to join the lab of @irenemiguel-aliaga.bsky.social at the @crick.ac.uk for a 12-month placement starting July 2025!
Interested in how the 🐁 gut changes during pregnancy? Check the project and eligibility criteria here: www.crick.ac.uk/careers-stud...
Interested in how the 🐁 gut changes during pregnancy? Check the project and eligibility criteria here: www.crick.ac.uk/careers-stud...
Reposted by Amélie Joly
Congratulations to @carovinuesa.bsky.social on receiving the 2026 FEBS | @embo.org Women in Science Award.
She is recognised for her scientific achievements and her impact as a role model within the life sciences community.
www.crick.ac.uk/news/2025-09...
She is recognised for her scientific achievements and her impact as a role model within the life sciences community.
www.crick.ac.uk/news/2025-09...
Carola Vinuesa receives FEBS | EMBO Women in Science Award
Carola Vinuesa, Principal Group Leader and Assistant Research Director at the Francis Crick Institute is to receive the 2026 FEBS | EMBO Women in Science Award for her scientific achievements as well ...
www.crick.ac.uk
September 9, 2025 at 3:49 PM
Congratulations to @carovinuesa.bsky.social on receiving the 2026 FEBS | @embo.org Women in Science Award.
She is recognised for her scientific achievements and her impact as a role model within the life sciences community.
www.crick.ac.uk/news/2025-09...
She is recognised for her scientific achievements and her impact as a role model within the life sciences community.
www.crick.ac.uk/news/2025-09...
Learning about the latest findings in neurogastroenterology and gut motility at #NeuroGastro2025 ! 🧠🥪
September 5, 2025 at 3:48 PM
Learning about the latest findings in neurogastroenterology and gut motility at #NeuroGastro2025 ! 🧠🥪
Happy and proud to share this story! 🎉
We show that, when it comes to juvenile malnutrition, sex really matters ♂️♀️🐁
We also uncover a crucial, sexually dimorphic role of FGF21 in these adaptations 💥
👇👇👇
We show that, when it comes to juvenile malnutrition, sex really matters ♂️♀️🐁
We also uncover a crucial, sexually dimorphic role of FGF21 in these adaptations 💥
👇👇👇
📢 New preprint:
“Liver FGF21 mediates sex-specific adaptation to juvenile protein malnutrition”
Led by @ameliejoly.bsky.social, co-supervised with @francoisleulier.bsky.social.
We’re proud to share this story.
👉 www.biorxiv.org/content/10.1...
“Liver FGF21 mediates sex-specific adaptation to juvenile protein malnutrition”
Led by @ameliejoly.bsky.social, co-supervised with @francoisleulier.bsky.social.
We’re proud to share this story.
👉 www.biorxiv.org/content/10.1...
Liver FGF21 mediates sex-specific adaptation to juvenile protein malnutrition
Dietary protein sufficiency during childhood is essential for healthy growth and tissue development. Chronic protein deficiency leads to stunting, height-for-age more than two standard deviations belo...
www.biorxiv.org
July 14, 2025 at 9:50 AM
Happy and proud to share this story! 🎉
We show that, when it comes to juvenile malnutrition, sex really matters ♂️♀️🐁
We also uncover a crucial, sexually dimorphic role of FGF21 in these adaptations 💥
👇👇👇
We show that, when it comes to juvenile malnutrition, sex really matters ♂️♀️🐁
We also uncover a crucial, sexually dimorphic role of FGF21 in these adaptations 💥
👇👇👇
Live from international Fondation L'Oréal- UNESCO For Women In Science award ceremony 🎉 Congratulations to the five inspiring laureates ✨
June 12, 2025 at 7:58 PM
Live from international Fondation L'Oréal- UNESCO For Women In Science award ceremony 🎉 Congratulations to the five inspiring laureates ✨
Reposted by Amélie Joly
Very happy to share our latest lab publication!
The hard work of @bboumard.bsky.social, Gwenn Le Meur and collaborators!
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila: Developmental Cell
authors.elsevier.com/a/1lDFi_Yv6z...
The hard work of @bboumard.bsky.social, Gwenn Le Meur and collaborators!
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila: Developmental Cell
authors.elsevier.com/a/1lDFi_Yv6z...
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila
Boumard et al. demonstrate gap-junction-dependent tissue-scale nucleotide sharing,
which impacts cellular sensitivity to perturbation of nucleotide homeostasis and replication
stress. Drosophila wing ...
www.cell.com
June 5, 2025 at 4:47 PM
Very happy to share our latest lab publication!
The hard work of @bboumard.bsky.social, Gwenn Le Meur and collaborators!
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila: Developmental Cell
authors.elsevier.com/a/1lDFi_Yv6z...
The hard work of @bboumard.bsky.social, Gwenn Le Meur and collaborators!
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila: Developmental Cell
authors.elsevier.com/a/1lDFi_Yv6z...
Nothing like ending a day of stimulating science with beautiful live music performed directly at the @crick.ac.uk 🎶🔬✨
Who needs a concert hall when the concert comes to you?
Who needs a concert hall when the concert comes to you?
May 21, 2025 at 6:08 PM
Nothing like ending a day of stimulating science with beautiful live music performed directly at the @crick.ac.uk 🎶🔬✨
Who needs a concert hall when the concert comes to you?
Who needs a concert hall when the concert comes to you?
Reposted by Amélie Joly
Today in the USA, women are TWICE as likely to DIE giving birth than their mothers were a generation ago.
And TRUMP's War on Women continues with ending the landmark Women's Health Study: www.science.org/content/arti...
And TRUMP's War on Women continues with ending the landmark Women's Health Study: www.science.org/content/arti...
NIH cancels its first and largest study centered on women
The Women’s Health Initiative has produced numerous influential findings
www.science.org
April 23, 2025 at 4:47 PM
Today in the USA, women are TWICE as likely to DIE giving birth than their mothers were a generation ago.
And TRUMP's War on Women continues with ending the landmark Women's Health Study: www.science.org/content/arti...
And TRUMP's War on Women continues with ending the landmark Women's Health Study: www.science.org/content/arti...
It's the beginning of a new adventure: I just started as a postdoctoral researcher at the @crick.ac.uk in the group of @irenemiguel-aliaga.bsky.social 🎉
I'll be working on #SexDifferences and reproductive remodelling of the gastro-intestinal tract in 🐭
Excited and grateful for this opportunity!
I'll be working on #SexDifferences and reproductive remodelling of the gastro-intestinal tract in 🐭
Excited and grateful for this opportunity!
March 30, 2025 at 7:37 AM
It's the beginning of a new adventure: I just started as a postdoctoral researcher at the @crick.ac.uk in the group of @irenemiguel-aliaga.bsky.social 🎉
I'll be working on #SexDifferences and reproductive remodelling of the gastro-intestinal tract in 🐭
Excited and grateful for this opportunity!
I'll be working on #SexDifferences and reproductive remodelling of the gastro-intestinal tract in 🐭
Excited and grateful for this opportunity!
Reposted by Amélie Joly
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
March 19, 2025 at 5:31 PM
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
Reposted by Amélie Joly
Breaking news: Thousands of researchers and their supporters, including recently fired federal workers, have gathered across the U.S. in response to layoffs and funding cuts ordered by the Trump administration. scim.ag/41zlPv4
Thousands gather across U.S. in Stand Up for Science events
Scientists rally across the country in response to layoffs and funding cuts ordered by the Trump administration
scim.ag
March 7, 2025 at 6:27 PM
Breaking news: Thousands of researchers and their supporters, including recently fired federal workers, have gathered across the U.S. in response to layoffs and funding cuts ordered by the Trump administration. scim.ag/41zlPv4
Reposted by Amélie Joly
On #WorldObesityDay 2025 we present a special focus issue: "Decoding the complex systems of obesity”. We explore organ cooperation, metabolic health & environmental factors like diet in obesity. www.cell.com/cell-metabol...
March 4, 2025 at 7:41 PM
On #WorldObesityDay 2025 we present a special focus issue: "Decoding the complex systems of obesity”. We explore organ cooperation, metabolic health & environmental factors like diet in obesity. www.cell.com/cell-metabol...
Reposted by Amélie Joly
Online now: An organism-level quantitative flux model of energy metabolism in mice
An organism-level quantitative flux model of energy metabolism in mice
Yuan et al. built an organism-level flux model of energy metabolism describing circulating nutrients’ oxidation, interconversion, release from storage, and storage fluxes. The model revealed that circulating nutrients present higher cycling than oxidation…
dlvr.it
February 20, 2025 at 4:42 PM
Online now: An organism-level quantitative flux model of energy metabolism in mice
Reposted by Amélie Joly
@physoc.bsky.social has a starter pack of physiologists. Hooray!! go.bsky.app/2KU1XD6
February 13, 2025 at 6:57 PM
@physoc.bsky.social has a starter pack of physiologists. Hooray!! go.bsky.app/2KU1XD6
Happy 10th International day of women and girls in science 🎉👩🏼🔬
I'm convinced that the contributions of scientific women are crucial to build an inclusive, resilient and sustainable future 🌍
Join the @unesco.org campaign #EveryVoiceInScience to spread the word! 📢
I'm convinced that the contributions of scientific women are crucial to build an inclusive, resilient and sustainable future 🌍
Join the @unesco.org campaign #EveryVoiceInScience to spread the word! 📢
February 11, 2025 at 7:26 AM
Happy 10th International day of women and girls in science 🎉👩🏼🔬
I'm convinced that the contributions of scientific women are crucial to build an inclusive, resilient and sustainable future 🌍
Join the @unesco.org campaign #EveryVoiceInScience to spread the word! 📢
I'm convinced that the contributions of scientific women are crucial to build an inclusive, resilient and sustainable future 🌍
Join the @unesco.org campaign #EveryVoiceInScience to spread the word! 📢
Reposted by Amélie Joly
Latest preprint from the Lab, co-led by Cathy Ramos, lecturer in the team and pushed to the final line by Longwei Bai, Ph’d candidate.
Deals with microbiome (what else… 😉), guts and steroid hormone in flies.
#MicroSky #MicrobiomeSky #SymbioSky #DevBio #Drosofeed
www.biorxiv.org/content/10.1...
Deals with microbiome (what else… 😉), guts and steroid hormone in flies.
#MicroSky #MicrobiomeSky #SymbioSky #DevBio #Drosofeed
www.biorxiv.org/content/10.1...
Drosophila larval gut transcriptome reveals a microbe-mediated intestinal tissue growth via Ecdysone during adaptive growth
Juvenile growth is an adaptive trait since chronic undernutrition leads to reduced growth rate and delayed maturation. Using Drosophila and mouse gnotobiotic models, we previously established the evol...
www.biorxiv.org
February 8, 2025 at 1:25 PM
Latest preprint from the Lab, co-led by Cathy Ramos, lecturer in the team and pushed to the final line by Longwei Bai, Ph’d candidate.
Deals with microbiome (what else… 😉), guts and steroid hormone in flies.
#MicroSky #MicrobiomeSky #SymbioSky #DevBio #Drosofeed
www.biorxiv.org/content/10.1...
Deals with microbiome (what else… 😉), guts and steroid hormone in flies.
#MicroSky #MicrobiomeSky #SymbioSky #DevBio #Drosofeed
www.biorxiv.org/content/10.1...
Honored to have been invited by my former high school to speak to over 300 young girls about my journey as a scientist 👩🔬
I hope my story inspired them to aim high and never doubt their potential.
Thanks @domilucky.bsky.social and Xavier Andrieu for making it happen 🙏
I hope my story inspired them to aim high and never doubt their potential.
Thanks @domilucky.bsky.social and Xavier Andrieu for making it happen 🙏
January 17, 2025 at 10:17 AM
Honored to have been invited by my former high school to speak to over 300 young girls about my journey as a scientist 👩🔬
I hope my story inspired them to aim high and never doubt their potential.
Thanks @domilucky.bsky.social and Xavier Andrieu for making it happen 🙏
I hope my story inspired them to aim high and never doubt their potential.
Thanks @domilucky.bsky.social and Xavier Andrieu for making it happen 🙏