Anthony Mathelier
@amathelier.bsky.social
Computational biologist interested in gene expression regulation.
Associate Director and Group Leader at Norwegian Centre for Molecular Biosciences and Medicine, University of Oslo, Nordic EMBL Partnership for Molecular Medicine.
https://mathelierlab.com
Associate Director and Group Leader at Norwegian Centre for Molecular Biosciences and Medicine, University of Oslo, Nordic EMBL Partnership for Molecular Medicine.
https://mathelierlab.com
Pinned
Anthony Mathelier
@amathelier.bsky.social
· Nov 18
🧵 Bioinformatics faces a critical challenge: despite its importance, software quality often falls short due to the lack of proper development practices.
In our latest paper, we advocate for improving software quality in bioinformatics through teamwork.
academic.oup.com/bioinformati...
In our latest paper, we advocate for improving software quality in bioinformatics through teamwork.
academic.oup.com/bioinformati...
Reposted by Anthony Mathelier
Great opportunity to join the IGBMC as a Group Leader in Computational Biology ! Happy to discuss it if you like. Please share !
The IGBMC is recruiting a new Computational Biology Group Leader through the ENACT AI Chair for Scientific Discoveries, covering cancer, developmental, and structural biology. Join one of Europe’s leading life science centers!
cluster-ia-enact.ai/appels-a-pro...
Deadline: Jan 7, 2026
cluster-ia-enact.ai/appels-a-pro...
Deadline: Jan 7, 2026
November 13, 2025 at 12:54 PM
Great opportunity to join the IGBMC as a Group Leader in Computational Biology ! Happy to discuss it if you like. Please share !
This recognition by the community through citations truly belongs to all trainees, collaborators, and the community driving our work forward. A recognition of the importance of keeping open resources like JASPAR strong, which depends on shared effort and open scientific values.🙌
🎉 Congratulations to @amathelier.bsky.social for being recognised as being in the top 1% on the world's most highly cited researchers by @clarivate.com!
This highlights the contribution he has made to Biology and Biochemistry over the past 11 years!
@nordicembl.bsky.social @embl.org @uio.no
This highlights the contribution he has made to Biology and Biochemistry over the past 11 years!
@nordicembl.bsky.social @embl.org @uio.no
November 13, 2025 at 8:55 AM
This recognition by the community through citations truly belongs to all trainees, collaborators, and the community driving our work forward. A recognition of the importance of keeping open resources like JASPAR strong, which depends on shared effort and open scientific values.🙌
Reposted by Anthony Mathelier
📜 It's @ncmbm.bsky.social Newsletter time! You can now find out what we have been up to this past month; enjoy the read!
🧷 You can read it here 👉https://pub.dialogapi.no/v/c08f518b-1810-4084-848f-a29ba87d6fd0
@nordicembl.bsky.social @embl.org
🧷 You can read it here 👉https://pub.dialogapi.no/v/c08f518b-1810-4084-848f-a29ba87d6fd0
@nordicembl.bsky.social @embl.org
October 31, 2025 at 7:36 AM
📜 It's @ncmbm.bsky.social Newsletter time! You can now find out what we have been up to this past month; enjoy the read!
🧷 You can read it here 👉https://pub.dialogapi.no/v/c08f518b-1810-4084-848f-a29ba87d6fd0
@nordicembl.bsky.social @embl.org
🧷 You can read it here 👉https://pub.dialogapi.no/v/c08f518b-1810-4084-848f-a29ba87d6fd0
@nordicembl.bsky.social @embl.org
Reposted by Anthony Mathelier
gReLU: a comprehensive framework for DNA sequence modeling and design www.nature.com/articles/s4...
October 19, 2025 at 2:15 PM
gReLU: a comprehensive framework for DNA sequence modeling and design www.nature.com/articles/s4...
Is academia research becoming too competitive?
Grant applications success rates are falling!
search.app/Lvgp6
Grant applications success rates are falling!
search.app/Lvgp6
Is academic research becoming too competitive? Nature examines the data
Applications for European research grants increased in 2025. Scientists say they’re feeling the competition.
search.app
October 18, 2025 at 2:41 PM
Is academia research becoming too competitive?
Grant applications success rates are falling!
search.app/Lvgp6
Grant applications success rates are falling!
search.app/Lvgp6
Reposted by Anthony Mathelier
NCMBM marking Black History Month as part of its Tuesday Seminar series with Melaku Tadesse.
@uio.no @embl.org @nordicembl.bsky.social @amathelier.bsky.social
@uio.no @embl.org @nordicembl.bsky.social @amathelier.bsky.social
October 14, 2025 at 10:21 AM
NCMBM marking Black History Month as part of its Tuesday Seminar series with Melaku Tadesse.
@uio.no @embl.org @nordicembl.bsky.social @amathelier.bsky.social
@uio.no @embl.org @nordicembl.bsky.social @amathelier.bsky.social
Reposted by Anthony Mathelier
I'm very pleased to announce the official publication of our lab's paper "DNA mutagenesis driven by transcription factor competition with mismatch repair" in today's issue of Cell! www.cell.com/cell/abstrac...
DNA mutagenesis driven by transcription factor competition with mismatch repair
Competition between transcription factors and mismatch repair machinery drives localized
hypermutation at regulatory elements, with implications for cancer and genome evolution.
www.cell.com
October 2, 2025 at 11:37 PM
I'm very pleased to announce the official publication of our lab's paper "DNA mutagenesis driven by transcription factor competition with mismatch repair" in today's issue of Cell! www.cell.com/cell/abstrac...
Reposted by Anthony Mathelier
Activity of most genes is controlled by multiple enhancers, but is there activation coordinated? We leveraged Nanopore to identify a specific set of elements that are simultaneously accessible on the same DNA molecules and are coordinated in their activation. www.biorxiv.org/content/10.1...
August 18, 2025 at 12:23 PM
Activity of most genes is controlled by multiple enhancers, but is there activation coordinated? We leveraged Nanopore to identify a specific set of elements that are simultaneously accessible on the same DNA molecules and are coordinated in their activation. www.biorxiv.org/content/10.1...
Reposted by Anthony Mathelier
This is not a HiC map! Ever wondered if multiple enhancers get activated simultaneously? We measured chromatin accessibility on thousands of molecules by nanopore to create genome-wide co-accessibility maps. Proud of @mathias-boulanger.bsky.social @kasitc.bsky.social Biology in the thread👇
August 18, 2025 at 1:00 PM
This is not a HiC map! Ever wondered if multiple enhancers get activated simultaneously? We measured chromatin accessibility on thousands of molecules by nanopore to create genome-wide co-accessibility maps. Proud of @mathias-boulanger.bsky.social @kasitc.bsky.social Biology in the thread👇
Reposted by Anthony Mathelier
Reposted by Anthony Mathelier
Meet our newest Research Group Leader: Jess Ewald @ewaldlab.org 🇨🇦
Jess’s group takes a multi-disciplinary approach to identify and characterise chemical hazards to humans and ecosystems, using cell profiling data, machine learning, and integrative data analysis.
www.ebi.ac.uk/about/news/p...
🖥️🧬
Jess’s group takes a multi-disciplinary approach to identify and characterise chemical hazards to humans and ecosystems, using cell profiling data, machine learning, and integrative data analysis.
www.ebi.ac.uk/about/news/p...
🖥️🧬
Welcome: Jess Ewald
Jess Ewald, Research Group Leader at EMBL-EBI, uses cell profiling and AI to find and characterise chemical hazards to humans and ecosysystems.
www.ebi.ac.uk
September 3, 2025 at 9:07 AM
Meet our newest Research Group Leader: Jess Ewald @ewaldlab.org 🇨🇦
Jess’s group takes a multi-disciplinary approach to identify and characterise chemical hazards to humans and ecosystems, using cell profiling data, machine learning, and integrative data analysis.
www.ebi.ac.uk/about/news/p...
🖥️🧬
Jess’s group takes a multi-disciplinary approach to identify and characterise chemical hazards to humans and ecosystems, using cell profiling data, machine learning, and integrative data analysis.
www.ebi.ac.uk/about/news/p...
🖥️🧬
Great talk by Kata Ferenc on improving bioinformatics software quality through teamwork, sharing how we’ve approached this at @ncmbm.bsky.social
It sparked discussion on taking action within our Bioinformatics in Life Science initiative at @uio.no @biovitenskap.bsky.social
doi.org/10.1093/bioi...
It sparked discussion on taking action within our Bioinformatics in Life Science initiative at @uio.no @biovitenskap.bsky.social
doi.org/10.1093/bioi...
September 3, 2025 at 12:59 PM
Great talk by Kata Ferenc on improving bioinformatics software quality through teamwork, sharing how we’ve approached this at @ncmbm.bsky.social
It sparked discussion on taking action within our Bioinformatics in Life Science initiative at @uio.no @biovitenskap.bsky.social
doi.org/10.1093/bioi...
It sparked discussion on taking action within our Bioinformatics in Life Science initiative at @uio.no @biovitenskap.bsky.social
doi.org/10.1093/bioi...
Great read:
Beyond AlphaFold: how AI is decoding the grammar of the genome
www.nature.com/articles/d41...
Beyond AlphaFold: how AI is decoding the grammar of the genome
www.nature.com/articles/d41...
Beyond AlphaFold: how AI is decoding the grammar of the genome
Scientists are seeking to decipher the role of non-coding DNA in the human genome, helped by a suite of artificial-intelligence tools.
www.nature.com
August 21, 2025 at 4:53 AM
Great read:
Beyond AlphaFold: how AI is decoding the grammar of the genome
www.nature.com/articles/d41...
Beyond AlphaFold: how AI is decoding the grammar of the genome
www.nature.com/articles/d41...
Reposted by Anthony Mathelier
Two days left to apply for a 3-year postdoc in #Chromatin #Cancer #Epigenetics at University of Oslo, Norway, co-supervised by @amathelier.bsky.social You will be part of @cancelluio.bosky.social. We focus on #Sarcoma #Epigenome #CRISPR and Drug screen studies. Find out more here: shorturl.at/DtLHM
Postdoctoral Research Fellowship in Chromatin Biology and Cancer Epigenetics (283381) | University of Oslo
Job title: Postdoctoral Research Fellowship in Chromatin Biology and Cancer Epigenetics (283381), Employer: University of Oslo, Deadline: Wednesday, August 20, 2025
shorturl.at
August 18, 2025 at 7:46 AM
Two days left to apply for a 3-year postdoc in #Chromatin #Cancer #Epigenetics at University of Oslo, Norway, co-supervised by @amathelier.bsky.social You will be part of @cancelluio.bosky.social. We focus on #Sarcoma #Epigenome #CRISPR and Drug screen studies. Find out more here: shorturl.at/DtLHM
Reposted by Anthony Mathelier
We are hiring! A 3-year postdoc in #Chromatin #Cancer #Epigenetics at University of Oslo, Norway and co-supervised by @amathelier.bsky.social You will be part of @cancelluio.bosky.social. We focus on #Sarcoma #Epigenome #CRISPR and Drug screen studies. Find out more and apply here: shorturl.at/DtLHM
Postdoctoral Research Fellowship in Chromatin Biology and Cancer Epigenetics (283381) | University of Oslo
Job title: Postdoctoral Research Fellowship in Chromatin Biology and Cancer Epigenetics (283381), Employer: University of Oslo, Deadline: Wednesday, August 20, 2025
shorturl.at
August 12, 2025 at 9:08 AM
We are hiring! A 3-year postdoc in #Chromatin #Cancer #Epigenetics at University of Oslo, Norway and co-supervised by @amathelier.bsky.social You will be part of @cancelluio.bosky.social. We focus on #Sarcoma #Epigenome #CRISPR and Drug screen studies. Find out more and apply here: shorturl.at/DtLHM
Reposted by Anthony Mathelier
Only one more week to apply to do a postdoc with our group and this of
@thomasdwkim.bsky.social
@ncmbm.bsky.social
@nordicembl.bsky.social
! If you are interested, contact us or apply directly to the add. Please RT.
www.jobbnorge.no/en/available...
@thomasdwkim.bsky.social
@ncmbm.bsky.social
@nordicembl.bsky.social
! If you are interested, contact us or apply directly to the add. Please RT.
www.jobbnorge.no/en/available...
August 7, 2025 at 6:30 AM
Only one more week to apply to do a postdoc with our group and this of
@thomasdwkim.bsky.social
@ncmbm.bsky.social
@nordicembl.bsky.social
! If you are interested, contact us or apply directly to the add. Please RT.
www.jobbnorge.no/en/available...
@thomasdwkim.bsky.social
@ncmbm.bsky.social
@nordicembl.bsky.social
! If you are interested, contact us or apply directly to the add. Please RT.
www.jobbnorge.no/en/available...
Reposted by Anthony Mathelier
We’re looking for curious, innovative science leaders at EMBL Heidelberg! 🔬🧬🦠
Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.
Take a look at these four open positions 👇
Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.
Take a look at these four open positions 👇
August 7, 2025 at 8:28 AM
We’re looking for curious, innovative science leaders at EMBL Heidelberg! 🔬🧬🦠
Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.
Take a look at these four open positions 👇
Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.
Take a look at these four open positions 👇
Reposted by Anthony Mathelier
🌟 Looking to launch your independent research career in an environment built for collaboration, clinical relevance, and scientific excellence?
🔗To apply👉 www.jobbnorge.no/en/available...
📅 Deadline: 8 September 2025
🔗To apply👉 www.jobbnorge.no/en/available...
📅 Deadline: 8 September 2025
www.jobbnorge.no
August 8, 2025 at 6:17 AM
🌟 Looking to launch your independent research career in an environment built for collaboration, clinical relevance, and scientific excellence?
🔗To apply👉 www.jobbnorge.no/en/available...
📅 Deadline: 8 September 2025
🔗To apply👉 www.jobbnorge.no/en/available...
📅 Deadline: 8 September 2025
Reposted by Anthony Mathelier
📢One month left to apply to our Group Leader position!
🌟A chance to be part of @nordicembl.bsky.social: “The Partnership connects us with an exceptional network of researchers, facilities, and complementary expertise. It opens doors to meaningful scientific exchange”, says @amathelier.bsky.social.
🌟A chance to be part of @nordicembl.bsky.social: “The Partnership connects us with an exceptional network of researchers, facilities, and complementary expertise. It opens doors to meaningful scientific exchange”, says @amathelier.bsky.social.
August 8, 2025 at 6:17 AM
📢One month left to apply to our Group Leader position!
🌟A chance to be part of @nordicembl.bsky.social: “The Partnership connects us with an exceptional network of researchers, facilities, and complementary expertise. It opens doors to meaningful scientific exchange”, says @amathelier.bsky.social.
🌟A chance to be part of @nordicembl.bsky.social: “The Partnership connects us with an exceptional network of researchers, facilities, and complementary expertise. It opens doors to meaningful scientific exchange”, says @amathelier.bsky.social.
Reposted by Anthony Mathelier
"criteria for retraction have long included major errors that undermine a paper’s findings, not just fabrication and falsification" <- important to emphasize this. Retraction=/ misconduct
July 24, 2025 at 7:40 PM
"criteria for retraction have long included major errors that undermine a paper’s findings, not just fabrication and falsification" <- important to emphasize this. Retraction=/ misconduct
Reposted by Anthony Mathelier
It was indeed fantastic! Thank you so much to all the organizers for supporting this community. 🙏
July 25, 2025 at 7:37 AM
It was indeed fantastic! Thank you so much to all the organizers for supporting this community. 🙏
What a fantastic #ISMBECCB2025 conference it has been, with an outstanding #RegSys @iscb-regsys.bsky.social COSI track!
Thanks, everyone, for submitting, attending, presenting, and organizing @iscb.bsky.social @eccb-europe.bsky.social
Thanks, everyone, for submitting, attending, presenting, and organizing @iscb.bsky.social @eccb-europe.bsky.social
July 24, 2025 at 7:00 PM
What a fantastic #ISMBECCB2025 conference it has been, with an outstanding #RegSys @iscb-regsys.bsky.social COSI track!
Thanks, everyone, for submitting, attending, presenting, and organizing @iscb.bsky.social @eccb-europe.bsky.social
Thanks, everyone, for submitting, attending, presenting, and organizing @iscb.bsky.social @eccb-europe.bsky.social
Reposted by Anthony Mathelier
#ISMBECCB2025 It is good to be at a conference in 2025 of a society that reminds us that “equity, diversity and inclusion are essential to how the Society operates, evolves and envisions the future”. www.iscb.org/iscb-news-it... @iscb.bsky.social
June 23, 2025: ISCB's June 2025 Newsletter
ISCB - International Society for Computational Biology
www.iscb.org
July 22, 2025 at 11:33 AM
#ISMBECCB2025 It is good to be at a conference in 2025 of a society that reminds us that “equity, diversity and inclusion are essential to how the Society operates, evolves and envisions the future”. www.iscb.org/iscb-news-it... @iscb.bsky.social
Reposted by Anthony Mathelier
Next is
@damlaob to talk about putting new Deep learning models of TFs into #Jaspardb #RegSys #ismbeccb2025 @amathelier.bsky.social
@damlaob to talk about putting new Deep learning models of TFs into #Jaspardb #RegSys #ismbeccb2025 @amathelier.bsky.social
July 23, 2025 at 11:50 AM
Next is
@damlaob to talk about putting new Deep learning models of TFs into #Jaspardb #RegSys #ismbeccb2025 @amathelier.bsky.social
@damlaob to talk about putting new Deep learning models of TFs into #Jaspardb #RegSys #ismbeccb2025 @amathelier.bsky.social
Our own Damla @damlaob.bsky.social making a great presentation of the upcoming updates of JASPAR and UniBind with BPnet DL models at #RegSys @iscb-regsys.bsky.social #ISMBECCB2025
Chat with her at her poster D-485.
Chat with her at her poster D-485.
July 23, 2025 at 11:55 AM
Our own Damla @damlaob.bsky.social making a great presentation of the upcoming updates of JASPAR and UniBind with BPnet DL models at #RegSys @iscb-regsys.bsky.social #ISMBECCB2025
Chat with her at her poster D-485.
Chat with her at her poster D-485.