Alissa Rothchild
@alissarothchild.bsky.social
UMass Amherst Assistant Professor | alveolar macrophage and TB immunologist | transcriptome wrangler | New England bike commuter and hiker
#immunology #Tuberculosis #macrophages
Lab website: https://rothchildlab.com/
#immunology #Tuberculosis #macrophages
Lab website: https://rothchildlab.com/
Reposted by Alissa Rothchild
First impressions count in #TB. Andrea Cooper @uniofleicester.bsky.social discusses studies by @wjbranchett.bsky.social et al. (rupress.org/jem/article/...) and @bengern.bsky.social et al. (rupress.org/jem/article/...), in Insights: rupress.org/jem/article/...
November 4, 2025 at 2:45 PM
First impressions count in #TB. Andrea Cooper @uniofleicester.bsky.social discusses studies by @wjbranchett.bsky.social et al. (rupress.org/jem/article/...) and @bengern.bsky.social et al. (rupress.org/jem/article/...), in Insights: rupress.org/jem/article/...
Reposted by Alissa Rothchild
Donald Trump is weak. He’s a bully. And when we won’t bow down to kings or to bullies, they start to lose their power.
The American people do not bow down.
The American people do not bow down.
October 18, 2025 at 7:52 PM
Donald Trump is weak. He’s a bully. And when we won’t bow down to kings or to bullies, they start to lose their power.
The American people do not bow down.
The American people do not bow down.
🚨Job posting! #UMassAmherst Department of Veterinary and Animal Sciences is hiring a TT faculty member in #Immunology. Both fundamental and translational areas considered. Please spread the word!
careers.umass.edu/amherst/en-u...
careers.umass.edu/amherst/en-u...
Details - Assistant Professor - Immunology | Human Resources | UMass Amherst
careers.umass.edu
October 15, 2025 at 9:07 PM
🚨Job posting! #UMassAmherst Department of Veterinary and Animal Sciences is hiring a TT faculty member in #Immunology. Both fundamental and translational areas considered. Please spread the word!
careers.umass.edu/amherst/en-u...
careers.umass.edu/amherst/en-u...
Reposted by Alissa Rothchild
UMass Amherst Microbiology is hiring a tenure-track virologist. Come work with me! 🦠🧪
careers.umass.edu/amherst/en-u...
careers.umass.edu/amherst/en-u...
Details - Assistant Professor - Virology | Human Resources | UMass Amherst
careers.umass.edu
October 2, 2025 at 2:51 PM
UMass Amherst Microbiology is hiring a tenure-track virologist. Come work with me! 🦠🧪
careers.umass.edu/amherst/en-u...
careers.umass.edu/amherst/en-u...
Reposted by Alissa Rothchild
We are hiring! Please circulate in your networks. Join us in beautiful warm and wonderful KZN to answer some important questions about asymptomatic / subclinical TB.
#TBsky #IDsky 🧪
#TBsky #IDsky 🧪
📢 AHRI is #hiring for 2️⃣ key roles for an exciting new study on asymptomatic TB transmission.
Successful candidates will join the leadership of the study, working closely with our director for clinical trials Limakatso Lebina & @emilybethwong.bsky.social
More ➡️ ahri.wd3.myworkdayjobs.com/AHRI1
Successful candidates will join the leadership of the study, working closely with our director for clinical trials Limakatso Lebina & @emilybethwong.bsky.social
More ➡️ ahri.wd3.myworkdayjobs.com/AHRI1
August 21, 2025 at 3:25 PM
Reposted by Alissa Rothchild
We are hiring! The Dept of Microbiology and Molecular Genetics is looking for faculty at the Assistant or Associate professor level (tenure track). Please consider joining our vibrant microbiology and immunology community at the University of Pittsburgh School of medicine
August 20, 2025 at 7:41 PM
We are hiring! The Dept of Microbiology and Molecular Genetics is looking for faculty at the Assistant or Associate professor level (tenure track). Please consider joining our vibrant microbiology and immunology community at the University of Pittsburgh School of medicine
Happy to share our new pre-print, led by PhD student Linh Pham! We examine inhibition of MHC II expression by NRF2 during Mtb infection and its impact on innate-adaptive crosstalk. Special thanks to the Behar lab who helped us set up a T cell co-culture system for the project! #TB #immunology
NRF2 inhibition of alveolar macrophage MHC II expression during Mycobacterium tuberculosis infection https://www.biorxiv.org/content/10.1101/2025.08.16.670319v1
August 18, 2025 at 8:53 PM
Happy to share our new pre-print, led by PhD student Linh Pham! We examine inhibition of MHC II expression by NRF2 during Mtb infection and its impact on innate-adaptive crosstalk. Special thanks to the Behar lab who helped us set up a T cell co-culture system for the project! #TB #immunology
Reposted by Alissa Rothchild
Tragically, the NIH is finding any reason it can to cancel grants, including critical research into the nature and function of mycobacterium tuberculosis. www.washingtonpost.com/science/2025...
Trump officials halt ‘dangerous’ research, overriding NIH career scientists
The Trump administration’s actions on NIH gain-of-function research have raised concerns among scientists, who argue the move could block experiments that are safe and potentially lead to new treatmen...
www.washingtonpost.com
July 18, 2025 at 3:45 PM
Tragically, the NIH is finding any reason it can to cancel grants, including critical research into the nature and function of mycobacterium tuberculosis. www.washingtonpost.com/science/2025...
Reposted by Alissa Rothchild
NEW: In an unprecedented move, the NIH will soon disinvite dozens of scientists about to take positions on advisory councils that make final decisions on grant funding.
NIH staff were told to select others aligned with the Trump administration and told to expect placements by political appointees.
NIH staff were told to select others aligned with the Trump administration and told to expect placements by political appointees.
Exclusive: NIH to dismiss dozens of grant reviewers to align with Trump priorities
The move would undo years of work, leaving advisory councils understaffed, and without the full expertise needed for reviews.
www.nature.com
July 14, 2025 at 11:25 PM
NEW: In an unprecedented move, the NIH will soon disinvite dozens of scientists about to take positions on advisory councils that make final decisions on grant funding.
NIH staff were told to select others aligned with the Trump administration and told to expect placements by political appointees.
NIH staff were told to select others aligned with the Trump administration and told to expect placements by political appointees.
Reposted by Alissa Rothchild
‼️ Save the date! ‼️ Tuberculosis: Understanding the Disease Across Scales Keystone 2026 on March 23-26 in Cape Town, South Africa 🇿🇦 Very excited to organise this meeting with Digby, Bree and Margarida
Short Talk Abstract Deadline: Nov. 24, 2025
www.keystonesymposia.org/conferences/...
Short Talk Abstract Deadline: Nov. 24, 2025
www.keystonesymposia.org/conferences/...
June 16, 2025 at 3:19 PM
‼️ Save the date! ‼️ Tuberculosis: Understanding the Disease Across Scales Keystone 2026 on March 23-26 in Cape Town, South Africa 🇿🇦 Very excited to organise this meeting with Digby, Bree and Margarida
Short Talk Abstract Deadline: Nov. 24, 2025
www.keystonesymposia.org/conferences/...
Short Talk Abstract Deadline: Nov. 24, 2025
www.keystonesymposia.org/conferences/...
Reposted by Alissa Rothchild
WOW!.. 8500+ supporting cast heroes (that's us!) have already signed our Letter of Support for the brave NIH heroes who laid down their case in the historic #BethesdaDeclaration.
Add your name here actionnetwork.org/forms/add-na... & stand up to save science & health in America.
#StandUpForScience
Add your name here actionnetwork.org/forms/add-na... & stand up to save science & health in America.
#StandUpForScience
ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff
Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.
actionnetwork.org
June 10, 2025 at 3:38 PM
WOW!.. 8500+ supporting cast heroes (that's us!) have already signed our Letter of Support for the brave NIH heroes who laid down their case in the historic #BethesdaDeclaration.
Add your name here actionnetwork.org/forms/add-na... & stand up to save science & health in America.
#StandUpForScience
Add your name here actionnetwork.org/forms/add-na... & stand up to save science & health in America.
#StandUpForScience
Reposted by Alissa Rothchild
How bad will it be? Catastrophic.
Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come.
But, this is the WH's *proposed* budget.
Speak up now before it is too late.
(inflation adjusted $-s below)
Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come.
But, this is the WH's *proposed* budget.
Speak up now before it is too late.
(inflation adjusted $-s below)
May 31, 2025 at 2:50 AM
Reposted by Alissa Rothchild
Delighted to see this piece with Victor Ambros, @carlbergstrom.com, Carol Greider, @michaelemann.bsky.social, and @briannosek.bsky.social in the wild.
Trump’s new ‘gold standard’ rule will destroy American science as we know it
@standupforscience.bsky.social
www.theguardian.com/commentisfre...
Trump’s new ‘gold standard’ rule will destroy American science as we know it
@standupforscience.bsky.social
www.theguardian.com/commentisfre...
Trump’s new ‘gold standard’ rule will destroy American science as we know it | Colette Delawalla
The new executive order allows political appointees to undermine research they oppose, paving the way to state-controlled science
www.theguardian.com
May 29, 2025 at 1:41 PM
Delighted to see this piece with Victor Ambros, @carlbergstrom.com, Carol Greider, @michaelemann.bsky.social, and @briannosek.bsky.social in the wild.
Trump’s new ‘gold standard’ rule will destroy American science as we know it
@standupforscience.bsky.social
www.theguardian.com/commentisfre...
Trump’s new ‘gold standard’ rule will destroy American science as we know it
@standupforscience.bsky.social
www.theguardian.com/commentisfre...
Reposted by Alissa Rothchild
There’s been some “advice” coming from some quarters for scientists not to focus on DEI-related funding cuts.
I wholly reject this concept.
Cutting programs designed to reduce science and healthcare disparities is as detrimental to science as anything else, both morally and functionally.
I wholly reject this concept.
Cutting programs designed to reduce science and healthcare disparities is as detrimental to science as anything else, both morally and functionally.
May 17, 2025 at 2:37 PM
There’s been some “advice” coming from some quarters for scientists not to focus on DEI-related funding cuts.
I wholly reject this concept.
Cutting programs designed to reduce science and healthcare disparities is as detrimental to science as anything else, both morally and functionally.
I wholly reject this concept.
Cutting programs designed to reduce science and healthcare disparities is as detrimental to science as anything else, both morally and functionally.
Reposted by Alissa Rothchild
New NIH Notice "expiring" a large number of funding opportunities because
"We have identified a number of Notices of Funding Opportunities (NOFOs) that were not expired or reissued as indicated in the implementation plan outlined in NOT-OD-24-085."
grants.nih.gov/grants/guide...
"We have identified a number of Notices of Funding Opportunities (NOFOs) that were not expired or reissued as indicated in the implementation plan outlined in NOT-OD-24-085."
grants.nih.gov/grants/guide...
NOT-OD-25-113: Notice of Early Expiration of Notices of Funding Opportunities Related to the Simplified Review Framework for NIH Research Grant Applications
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Early Expiration of Notices of Funding Opportunities Related to the Simplified Review Framework for NIH Resea...
grants.nih.gov
May 16, 2025 at 1:58 PM
New NIH Notice "expiring" a large number of funding opportunities because
"We have identified a number of Notices of Funding Opportunities (NOFOs) that were not expired or reissued as indicated in the implementation plan outlined in NOT-OD-24-085."
grants.nih.gov/grants/guide...
"We have identified a number of Notices of Funding Opportunities (NOFOs) that were not expired or reissued as indicated in the implementation plan outlined in NOT-OD-24-085."
grants.nih.gov/grants/guide...
Congratulations @payalyokota.bsky.social! Fantastic work!
Excited to share our latest study
@cp-immunity.bsky.social. Heartfelt thanks to the editorial and review teams , to my co-first @yeungadventures.bsky.social, our co-authors, and to @khannakm.bsky.social
for his outstanding mentorship throughout! Pls read/share!👇
www.cell.com/immunity/ful...
@cp-immunity.bsky.social. Heartfelt thanks to the editorial and review teams , to my co-first @yeungadventures.bsky.social, our co-authors, and to @khannakm.bsky.social
for his outstanding mentorship throughout! Pls read/share!👇
www.cell.com/immunity/ful...
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung
infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential
role of nerve- and airway-associated...
www.cell.com
April 25, 2025 at 4:10 PM
Congratulations @payalyokota.bsky.social! Fantastic work!
Reposted by Alissa Rothchild
ACTION ITEM-----ACTION ITEM
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
the word alert is in a purple circle
ALT: the word alert is in a purple circle
media.tenor.com
April 23, 2025 at 6:03 PM
ACTION ITEM-----ACTION ITEM
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
Reposted by Alissa Rothchild
Updated funding curves...
Data downloaded today, but plotted through 4/15 to correct for NIH Reporter lag time).
New and Competitive Renewal Awards first
Awards being made but the rate remains lower than normal
1/2
Data downloaded today, but plotted through 4/15 to correct for NIH Reporter lag time).
New and Competitive Renewal Awards first
Awards being made but the rate remains lower than normal
1/2
April 23, 2025 at 12:36 PM
Updated funding curves...
Data downloaded today, but plotted through 4/15 to correct for NIH Reporter lag time).
New and Competitive Renewal Awards first
Awards being made but the rate remains lower than normal
1/2
Data downloaded today, but plotted through 4/15 to correct for NIH Reporter lag time).
New and Competitive Renewal Awards first
Awards being made but the rate remains lower than normal
1/2
Reposted by Alissa Rothchild
Faculty senates at Rutgers University, the University of Nebraska at Lincoln, the University of Indiana at Bloomington, and the University of Massachusetts at Amherst have passed resolutions calling for the creation of a mutual-defense compact. chroni.cl/4cBFrnu
These Faculty Senates Are Trying to Band Together to Stand Up to Trump
The idea of a compact among institutions is based on the idea that there’s strength in numbers, and it comes amid frustration that few presidents are speaking out against the administration’s actions ...
chroni.cl
April 15, 2025 at 1:40 PM
Faculty senates at Rutgers University, the University of Nebraska at Lincoln, the University of Indiana at Bloomington, and the University of Massachusetts at Amherst have passed resolutions calling for the creation of a mutual-defense compact. chroni.cl/4cBFrnu
Reposted by Alissa Rothchild
I'm taking action following the Trump administration's sudden revocation of international student visas in MA-02.
Their actions are unconstitutional, unconscionable, and unprecedented. We need answers.
Read more: mcgovern.house.gov/news/documen...
Their actions are unconstitutional, unconscionable, and unprecedented. We need answers.
Read more: mcgovern.house.gov/news/documen...
Press Releases | Congressman Jim McGovern
mcgovern.house.gov
April 14, 2025 at 4:46 PM
I'm taking action following the Trump administration's sudden revocation of international student visas in MA-02.
Their actions are unconstitutional, unconscionable, and unprecedented. We need answers.
Read more: mcgovern.house.gov/news/documen...
Their actions are unconstitutional, unconscionable, and unprecedented. We need answers.
Read more: mcgovern.house.gov/news/documen...
Reposted by Alissa Rothchild
An exciting finding for the TB community!
Erwin Schurr & team show people with HIV who are resistant to infection from Mycobacterium tuberculosis display activated alveolar macrophages and increased numbers of alveolar poly-cytotoxic T cells: buff.ly/xJ42sfP
Erwin Schurr & team show people with HIV who are resistant to infection from Mycobacterium tuberculosis display activated alveolar macrophages and increased numbers of alveolar poly-cytotoxic T cells: buff.ly/xJ42sfP
April 10, 2025 at 1:20 PM
An exciting finding for the TB community!
Erwin Schurr & team show people with HIV who are resistant to infection from Mycobacterium tuberculosis display activated alveolar macrophages and increased numbers of alveolar poly-cytotoxic T cells: buff.ly/xJ42sfP
Erwin Schurr & team show people with HIV who are resistant to infection from Mycobacterium tuberculosis display activated alveolar macrophages and increased numbers of alveolar poly-cytotoxic T cells: buff.ly/xJ42sfP
Cancellation of this TB "moonshot" would be devastating to the #TB research community, further reducing any chance for novel and innovative therapies to contain the global epidemic. On a personal note, I've learned so much from this amazing team. Just heartbreaking. #TBsky #Immunosky
Tuberculosis is not going away. If the cutting edge research goes away, #TB will rage on. Harvard is being targeted including the TB Immunology contract and that trickles down to all of us working on these studies. Progress will be halted. And TB will flourish. www.bostonglobe.com/2025/04/08/m...
‘This looks bad.’ A Harvard infectious disease researcher is targeted in Trump’s review. - The Boston Globe
Sarah Fortune’s tuberculosis research was the number one project on a list of threatened funding.
www.bostonglobe.com
April 8, 2025 at 9:00 PM
Cancellation of this TB "moonshot" would be devastating to the #TB research community, further reducing any chance for novel and innovative therapies to contain the global epidemic. On a personal note, I've learned so much from this amazing team. Just heartbreaking. #TBsky #Immunosky
Greenfield, MA #HandsOff #SocialJusticeSingout Standing room only!
April 5, 2025 at 7:02 PM
Greenfield, MA #HandsOff #SocialJusticeSingout Standing room only!