Aisling Brady
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aislingbrady.bsky.social
Aisling Brady
@aislingbrady.bsky.social
Postdoctoral researcher at the University of Liverpool 👩‍🔬 you’ll probably find me talking about Salmonella and phages 🧫 or running 🏃‍♀️ or drinking coffee ☕️ or a beer 🍺 she/her 👩🏻‍🦰
Reposted by Aisling Brady
🚨#PhD studentship opportunity! Plasmids provide bacteria with antimicrobial resistance, but do they have more fundamental effects on behaviour? 🧫🦠💫🧟‍♂️

Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
MRC DiMeN Doctoral Training Partnership: Resistant zombies: how drug-resistance plasmids manipulate the behaviour of the opportunistic pathogen Pseudomonas aeruginosa at University of Liverpool on Fin...
PhD Project - MRC DiMeN Doctoral Training Partnership: Resistant zombies: how drug-resistance plasmids manipulate the behaviour of the opportunistic pathogen Pseudomonas aeruginosa at University of Li...
www.findaphd.com
November 18, 2025 at 9:38 AM
Reposted by Aisling Brady
Theres still time to apply for our PhD project on UPEC/immune cell interactions. Deadline December 4th
If you are interested in researching how drug resistant bacteria evade killing by our immune system, them this PhD project is for you. Come join the our team at Newcastle, in collaboration with University of Liverpool, and lead research at the interface of microbiology, immunology and metabolomics.
MRC DiMeN Doctoral Training Partnership: Hiding in plain sight: How multi-drug resistant pathogens evade detection and killing by human neutrophils at Newcastle University on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Hiding in plain sight: How multi-drug resistant pathogens evade detection and killing by human neutrophils at Newcastle University, listed on Fin...
www.findaphd.com
November 16, 2025 at 8:22 PM
Reposted by Aisling Brady
Final call! Abstract submissions for Annual Conference 2026 close at 23:59 GMT tonight. Submit your work and join us in Belfast: microb.io/AC26Abstracts #Microbio26
November 11, 2025 at 9:01 AM
Reposted by Aisling Brady
Excited to share our latest work, where we create Salmonella mutants deficient for cohorts of SPI-2 T3SS effectors. These strains can be used to efficiently identify particular effectors that contribute to SPI-2 phenotypes doi.org/10.1038/s414...
Salmonella multimutants enable efficient identification of SPI-2 effector protein function in gut inflammation and systemic colonization - Nature Communications
Intracellular Salmonella enterica uses a type III secretion system to secrete more than 30 effector proteins into host cells. Here, Newson et al. generate six mutant strains deficient in different set...
doi.org
November 10, 2025 at 8:02 AM
Reposted by Aisling Brady
Intracellular Salmonella hijacks the mitochondrial citrate carrier to evade host oxidative defenses
www.nature.com/articles/s41...
Intracellular Salmonella hijacks the mitochondrial citrate carrier to evade host oxidative defenses - Nature Communications
In this study, the authors show that Salmonella enterica serovar Typhimurium co-opts the host mitochondrial citrate carrier (CIC) to regulate the redox state of its vacuole, facilitating intracellular...
www.nature.com
November 6, 2025 at 11:54 PM
Reposted by Aisling Brady
One week to go! Abstract submissions for Annual Conference 2026 close at 23:59 GMT on Tuesday 11 November. If you study microbes, there’s a home for your work at #Microbio26
Submit your work to one of >20 available sessions at: microb.io/AC26Abstracts
November 4, 2025 at 11:01 AM
Reposted by Aisling Brady
🆕 | @uofgsii.bsky.social postgrad researchers have taken top honours in the @microbiologysociety.org Sir Howard Dalton Early Career Microbiologist of the Year competition.

Emma Davies (@cvrinfo.bsky.social) was named winner, with Phoebe Crossley (Microbiology) 3rd.

🔗 www.gla.ac.uk/schools/infe...
October 28, 2025 at 11:44 AM
Reposted by Aisling Brady
I am delighted to be a co-investigator on this newly funded Wellcome Discovery Award. Excited to begin work with the team (including those not on Bluesky!)
@jayhinton.bsky.social @roygoodacre.bsky.social @lisamaierlab.bsky.social @blancaps.bsky.social
NEWS | Professor @jayhinton.bsky.social and an international team have been awarded £4.56M Wellcome Discovery Award to investigate natural human resistance to Salmonella

🔗 bit.ly/4hujsRG

@livuninews.bsky.social | #TeamLivUni
October 27, 2025 at 3:30 PM
Reposted by Aisling Brady
NEWS | Professor @jayhinton.bsky.social and an international team have been awarded £4.56M Wellcome Discovery Award to investigate natural human resistance to Salmonella

🔗 bit.ly/4hujsRG

@livuninews.bsky.social | #TeamLivUni
October 27, 2025 at 3:17 PM
Reposted by Aisling Brady
New paper with my (amazing) friend and mentor @jrpenades.bsky.social
Really looking forward to see what plasmid aficionados think of this one!!
With @asantoslopez.bsky.social @wfigueroac3.bsky.social Akshay Sabins and others
www.cell.com/cell-reports...
Non-conjugative plasmids limit their mobility to persist in nature
Sabnis et al. explain why non-conjugative plasmids move at a low rate in nature. While increased mobility can easily evolve by incorporating phage DNA into plasmids, this is disadvantageous because it...
www.cell.com
October 22, 2025 at 1:12 PM
Reposted by Aisling Brady
After being with the journal since its very inception, the time has come for me to step back from Microbial Genomics. This is a wonderful opportunity to have a leadership role in one of the leading journals for microbial genomics research

microbiologysociety.org/news/society...
<i>Microbial Genomics </i> Deputy Editor-in-Chief: Call for Expressions of interest
microbiologysociety.org
October 7, 2025 at 8:44 AM
Reposted by Aisling Brady
Why not apply for a Microbiology Society grant to support your attendance at @shigellameeting.bsky.social?

microbiologysociety.org/grants/all-g...
microbiologysociety.org
September 26, 2025 at 11:24 AM
Reposted by Aisling Brady
Happy Postdoc Appreciation Week! 💙

To celebrate postdocs we've teamed up with @proteintech.bsky.social to organise free social events for staff and students at universities.

Register for a free event near you:
pintofscience.co.uk/paw/

#NPAW2025 #CelebratePostdocs
September 15, 2025 at 8:38 AM
cf-PICIs make their own capsids, steal phage tails and jump across species 😱
We discovered a new horizontal gene transfer mechanism: tail-less cf-PICIs hijack free phage tails extracellularly, forming infectious chimeric virions that drive both intra- and inter-species transfer among bacteria. @jonaszpatkowski.bsky.social @tcostalab.bsky.social @jrpenades.bsky.social
September 10, 2025 at 6:53 AM
What is everyone's favourite review on anti-phage/defence systems? Ideally as an introduction to the concept/key systems for undergraduate level without expertise in phage biology #MicroSky #PhageSky
August 27, 2025 at 10:29 AM
Back to work this week after a fantastic time in New Hampshire for the GRS/GRC Salmonella 2025! My head is absolutely buzzing with new ideas 🤩💡 #GRC #Salmonella #MicroSky
August 19, 2025 at 3:13 PM
Reposted by Aisling Brady
#phagesky

I am looking for phages infecting Streptococcus pneumoniae to test a phenotype - does anyone have some and willing to share ?

Repost appreciated :)
August 19, 2025 at 8:11 AM
Reposted by Aisling Brady
Delighted to have this review out with @jpjhall.bsky.social!

We discuss the risk of transmission of antimicrobial resistance in the hospital sink drain microbiome, highlight studies providing evidence of transfer, and consider strategies to mitigate these risks 🪠🦠

doi.org/10.1038/s442...
The hospital sink drain microbiome as a melting pot for AMR transmission to nosocomial pathogens - npj Antimicrobials and Resistance
npj Antimicrobials and Resistance - The hospital sink drain microbiome as a melting pot for AMR transmission to nosocomial pathogens
doi.org
July 30, 2025 at 8:14 AM
Reposted by Aisling Brady
There are half a million cases of invasive non-Typhoidal Salmonella (iNTS) every year and while you might know S. Typhimurim and Enteritidis, you may not have heard of S. Panama 💩 🩸 🧫 💊 Check out our latest in @lancetmicrobe.bsky.social doi.org/10.1016/j.la... and the 🧵 below to find out more 1/n
July 27, 2025 at 8:35 AM
Reposted by Aisling Brady
#phage #phagesky

A bacterial host factor confines phage localization for excluding the infected compartment through cell division: www.cell.com/cell-reports...
A bacterial host factor confines phage localization for excluding the infected compartment through cell division
Pollak Fiyaksel et al. describe YjbH, a helix-turn-helix DNA-binding protein in Bacillus subtilis, conserved among gram-positive bacteria. YjbH binds the incoming phage genome, confines phage producti...
www.cell.com
July 17, 2025 at 1:08 PM
Reposted by Aisling Brady
Congratulations to Dr Tessa Cornell, a Postdoctoral Research Associate, who has recently been awarded a Soulsby Fellowship for her project which responds to national One Health priorities and evidence gaps in The Gambia, West Africa.

➡️ bit.ly/3TUwuNv

#TeamLivUni
July 4, 2025 at 3:11 PM
For anyone who missed it earlier this year, I really recommend giving this a listen! @halllab.bsky.social has been doing some really amazing public engagement work 🌟
Peter Wildy Prize Lecture and Interview with Prof. Lindsay Hall from Annual Conference 2025 is now available on YouTube. Watch the full interview and lecture: 'Guardians of the Gut Bringing Microbiome Science to Life through Public Engagement' microb.io/40s1zvB #Microbio25
July 3, 2025 at 11:27 AM
Reposted by Aisling Brady
Reposted by Aisling Brady
📣 Position available: Research tech in microbial experimental evolution! Working alongside postdoc Louise Flanagan (@flanagella.bsky.social) on understanding how Pseudomonas evolves resistance to antibiotics. 🦠🧫
Closing 9 July #Microsky
www.jobs.manchester.ac.uk/Job/JobDetai...
Research Technician :Oxford Road
www.jobs.manchester.ac.uk
June 26, 2025 at 3:32 PM